ANALYTICAL BIOCHEMISTRY
·
2018
·
IF 2.275
Fanjun Zhu,Guangying Zhao,Wenchao Dou
Herein, a non-enzymatic sandwich-type electrochemical immunoassay was fabricated for quantitative monitoring of Escherichia coli O157:H7 ( E. coli O157:H7). Silica coated Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4 @SiO 2 ) were modified with mouse anti- E. coli O157:H7 monoclonal antibody (Ab 1 ) to act as capture probes to reduce detection time and increase the sensitivity of the immunoassay . The Au@Pt nanoparticles were loaded on neutral red (NR) functionalized graphene to form composite complex rGO-NR-Au@Pt. rGO-NR-Au@Pt has high specific surface area and good biocompatibility. rGO-NR-Au@Pt was used as the carriers of detection antibodies (Ab 2 ). Au@Pt catalyzed the reduction of hydrogen peroxide (H 2 O 2 ) to detection of E. coli O157:H7 with the thionine (TH) as electron mediator to effectually amply the current signal. Under the optimized conditions, a linear relationship between the reduction peak current change (ΔI pc ) and the logarithm of the E. coli O157:H7 concentration is obtained in the range from 4.0 × 10 3 to 4.0 × 10 8 CFU mL −1 and the limit of detection (LOD) is 4.5 × 10 2 CFU mL -1 at a signal-to-noise ratio of 3. The immunoassay exhibits acceptable specificity, reproducibility and stability on the detection of E. coli O157:H7. Furthermore, the immunoassay showed good performance in pork and milk samples. The results suggest that this immunoassay will be promising in the food safety area.
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Nanoscale
·
2019
·Vol. 11
·期 18
·9091-9102
·
IF 6.97
Dahui Fang,Xuejun Tang,Limeng Yang,Dongyan Xu,Hongjie Zhang,Shucheng Sun,Zhigang Shao,Baolian Yi
Pt-Decorated Ir black (Pt@Ir) nanoparticles with two varying Pt mass fractions (Pt4@Ir96 and Pt16@Ir84) were generated by a facile method in water with the aid of Ir black. The Pt@Ir nanoparticles were investigated as a bifunctional oxygen catalysts for both the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) in acidic medium. Benefiting from the good dispersion of ultrafine Pt nanodots on the Ir black surface and the synergistic effect between the Pt and underlying Ir atoms, Pt@Ir nanoparticles have exhibited outstanding ORR activity and comparable OER performance in comparison with commercial Ir black. In particular, Pt16@Ir84 shows an ORR mass activity of 2.6 times that of commercial Pt black and exhibits much better bifunctional performances than a mixture of Pt black and Ir black with a Ir/Pt mass ratio of 50/50 (Pt50Ir50). Our work highlights the effectiveness of decorating Ir black with Pt nanodots to fabricate bifunctional oxygen catalysts.
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RSC Advances
·
2018
·Vol. 8
·期 51
·28909-28917
·
IF 2.936
Haoran Li,Chenglian Liu,Yan Wang,Jiajun Zheng,Binbin Fan,Ruifeng Li
ZSM-48 and ZSM-22 zeolites with similar Si/Al molar ratio have been treated with alkali to modify the pore structures and acidity, and alkali treated ZSM-22 and ZSM-48 samples have been characterized by X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), N2 adsorption/desorption, Nuclear Magnetic Resonance (NMR), NH3-Temperature Programmed Desorption (NH3-TPD) and Pyridine-Fourier Transform Infrared Spectroscopy (Py-FTIR). Characterization results indicate that NaOH treatment could improve the mesoporous structure for both ZSM-22 and ZSM-48. NaOH treatment modifies the acidity of ZSM-22 and ZSM-48 diversely. The n-hexane hydroisomerization performances of Pt supported protonic form ZSM-22 and ZSM-48 (Pt/HZSM-22 and Pt/HZSM-48) bifunctional catalysts have been evaluated in a fixed bed reactor. Catalytic results indicate that catalytic activity and selectivity depend on both pore structure and acidity of zeolites. In comparison of Pt/HZSM-22 and Pt/HZSM-48, Pt/HZSM-22 shows better n-hexane hydroisomerization performance at relatively low temperature (<300 °C), meanwhile, at relatively high temperature (>300 °C) Pt/HZSM-48 exhibits better catalytic performance. Moreover, alkali treated Pt/HZSM-48 could produce more di-branched isomer compared with alkali treated Pt/HZSM-22.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2019
·
IF 4.084
Yuan Xue,Shixiong Min,Fang Wang
Although black phosphorous (BP) and its derived materials have shown great potential for application in photocatalytic H 2 evolution reaction (HER), their HER activity and stability still remains unsatisfied mainly due to the insufficient charge separation, the lack of surface active sites, and the defect-riched nature of BP. Herein, we report that BP nanosheets decorated with in situ grown Pt (BP NSs/Pt) could act as a highly efficient catalyst for photocatalytic H 2 evolution in an Erythrosin B (ErB)-sensitized system under visible light irradiation (≥450 nm) in the presence of triethanolamine (TEOA) as sacrificial electron donor . It is found that BP NSs can provide large surface area for the confined growth of Pt nanoparticles with a high dispersion and a reduced size but also stabilize the loaded Pt nanoparticles by covalent bonds at the BP NSs/Pt interfaces. Moreover, BP NSs offer a fast electron transfer pathway to facilitate the photocatalytic HER over in situ grown Pt catalyst. As a result, BP NSs/Pt catalyst exhibits ∼6 times higher H 2 evolution activity than free Pt nanoparticles and an apparent quantum yield (AQY) of 0.57% at 500 nm irradiation in ErB-TEOA system. This work indicates the potential of BP NSs as an effective 2D matrix to construct numerous high performance photocatalysts and photocatalytic systems.
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BIOMATERIALS
·
2024
·
IF 12.8
Dan Wang,Wenqi Ma,Yuanyuan Zhang,Yufeng Wang,Lei Sun,Jue Jiang,Lianying Jiao,Runqing Li,Yujie Zhang,Mingzhen Zhang,Qi Zhou
Thyroid cancer is increasing globally, with anaplastic thyroid carcinoma (ATC) being the most aggressive type and having a poor prognosis. Current clinical treatments for thyroid cancer present numerous challenges, including invasiveness and the necessity of lifelong medication. Furthermore, a significant portion of patients with ATC experience cancer recurrence and metastasis. To overcome this dilemma, we developed a pH-responsive biomimetic nanocarrier (CLP@HP-A) through the incorporation of Chlorin e6 (Ce6) and Lenvatinib (Len) within hollow polydopamine nanoparticles (HP) that were further modified with platinum nanoparticles (Pt), enabling synergistic chemotherapy and sonodynamic therapy. The CLP@HP-A nanocarriers exhibited specific binding with galectin-3 receptors, facilitating their internalization through receptor-mediated endocytosis for targeted drug delivery. Upon exposure to ultrasound (US) irradiation, Ce6 rapidly generated reactive oxygen species (ROS) to induce significant oxidative stress and trigger apoptosis in tumor cells. Additionally, Pt not only alleviated tumor hypoxia by catalyzing the conversion of H 2 O 2 to oxygen (O 2 ) but also augmented intracellular ROS levels through the production of hydroxyl radicals (•OH), thereby enhancing the efficacy of sonodynamic therapy. Moreover, Len demonstrated a potent cytotoxic effect on thyroid cancer cells through the induction of apoptosis. Transcriptomics analysis findings additionally corroborated that CLP@HP-A effectively triggered cancer cell apoptosis, thereby serving as a crucial mechanism for its cytotoxic effects. In conclusion, the integration of sonodynamic/chemo combination therapy with targeted drug delivery systems offers a novel approach to the management of malignant tumors.
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RSC Advances
·
2015
·Vol. 5
·期 26
·19823-19829
·
IF 3.84
Zhenzhen Miao,Tianxiao Wu,Jingwei Li,Ting Yi,Yibo Zhang,Xiangguang Yang
The oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA) was efficiently catalyzed when Pt nanoparticles (NPs) were supported onto a Ce0.8Bi0.2O2−δ solid solution. 98% yield of FDCA was achieved within 30 min at room temperature and the catalyst was reused five times without much loss of FDCA selectivity. It is the first report on the oxidation of HMF, an alcohol and an aldehyde, effectively catalyzed by a ceria-based material supported Pt catalyst. The individual properties of the Pt NPs and the ceria-based support were retained and not affected after their combination. The superior oxygen activation ability of the Bi-doped ceria thoroughly changed the performance of the ceria supported Pt catalyst. Pt NPs were responsible for the formation of the Pt–alkoxide intermediate, followed by β-H elimination with the help of hydroxide ions. Bi-containing ceria accelerated the oxygen reduction process because of the presence of a large amount of oxygen vacancies and the cleavage of the peroxide intermediate promoted by bismuth. These specific functions were well incorporated during the catalytic oxidation cycle, leading to the generation of the highly efficient Pt/Ce0.8Bi0.2O2−δ catalyst for HMF oxidation at room temperature.
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Nanoscale
·
2024
·Vol. 16
·期 48
·22350-22359
·
IF 5.8
Weiping Xiao,Yue Zhang,Changwang Ke,Qin Zhao,Fengyan Han,Junpo Guo,Xiaofei Yang
Designing cost-effective and highly stable heterostructures with synergistic active sites could simultaneously catalyze the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) for (sea) water splitting. However, there are still challenges in maintaining the catalytic performance of individual materials and in constructing intimate interfaces. Herein, a novel corrosion engineering method is provided to prepare self-standing Fe2O3-Pt/NF nanoflowers where ultra-small amounts of Pt combined with Fe2O3 are in situ grown on nickel foam (NF) in the corrosion system of “H2PtCl6–NaCl–FeCl3”. The synthesized Fe2O3-Pt/NF shows the presence of a Pt–O bond, which can regulate the electronic structure of the active sites and optimize the binding energy of the reaction intermediates, leading to an improvement in catalytic performance. Compared with Pt/NF and FeOOH/NF, the Fe2O3-Pt/NF heterostructure exhibits remarkable electrocatalytic activities with overpotentials reaching 94 mV and 265 mV for the HER and OER, respectively, at a high current density of 100 mA cm−2 in alkaline solution. Furthermore, the self-assembled electrolytic cell employing Fe2O3-Pt/NF as the bifunctional electrode only requires potentials of 1.60 V and 1.61 V to achieve a current density of 100 mA cm−2 in overall water and seawater splitting, respectively. This material remained stable for 10 hours without obvious attenuation, indicating its good environmental adaptability and stability. Specifically, the enhanced catalytic activity and stability can be ascribed to the abundant active sites of nanoflowers, fast electron transfer rate of intimate interfaces, and strong electronic interaction between Pt atoms and Fe2O3. This work provides a new insight into the construction of highly efficient co-catalysts with intimate interfaces based on corrosion engineering methods.
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Nanoscale
·
2017
·Vol. 9
·期 31
·11077-11084
·
IF 7.367
Yalin Xiong,Yanling Ma,Junjie Li,Jingbo Huang,Yucong Yan,Hui Zhang,Jianbo Wu,Deren Yang
Bimetallic nanocrystals with a branched shape have received great interest as catalysts due to their unique structures and fascinating properties. However, the conventional synthetic approaches based on the island growth mode often lead to the dendritic nanostructures with inhomogeneous and uncontrolled branches. Here precise control over the number of branches has been realized in the deposition of Pt on Pd seeds through the Stranski–Krastanov growth mechanism. Based on such a growth mode, Pd@Pt core–shell hexapods and octapods have been generated by a seeded growth with Pd octahedra and cubes as the seeds, respectively. We found that Pt atoms are initially deposited on the side faces of Pd seeds through a layer-by-layer epitaxial growth in the presence of oleylamine (OAm), leading to a local strain focused at their corners. These strain-concentrated sites promote the subsequent island growth of Pt atoms at the corners of the Pd seeds, resulting in the Pd@Pt core–shell hexapods or octapods. Both the Pd@Pt core–shell hexapods and octapods exhibit the substantially enhanced catalytic properties in terms of activity and stability towards a methanol oxidation reaction (MOR) relative to the commercial Pt/C. Specifically, the Pd@Pt core–shell hexapods show the highest specific (1.97 mA cm−2) activity and mass activity (0.52 mA μgPt−1) for the MOR, which are 5.8 and 2.6 times higher than those of the commercial Pt/C, respectively. This enhancement can probably be attributed to their unique structures and the synergistic effect between Pt and Pd.
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JOURNAL OF CATALYSIS
·
2016
·
IF 7.354
Bao Zhang,Jun Li,Yuying Gao,Ruifeng Chong,Zhiliang Wang,Lin Guo,Xianwen Zhang,Can Li
Photocatalytic oxidation reactions provide a promising strategy for green synthesis of fine chemicals. However, the low photocatalytic efficiency and selectivity are the main obstacles. Herein, we report the ultrathin Bi 2 MoO 6 nanoplates with thickness of ∼17 nm which exhibit a superior performance in alcohol oxidation to corresponding aldehyde using O 2 under visible light irradiation, achieving ca. 29 times enhancement of activity compared with Bi 2 MoO 6 synthesized from traditional hydrothermal method (thickness of ∼250 nm). When Pt nanoparticles as cocatalyst are loaded on the surface of the ultrathin Bi 2 MoO 6 nanoplates, the photocatalytic performance is further enhanced. The remarkable enhancement of activity is attributed to the ultrathin 2D geometry of Bi 2 MoO 6 nanoplates, promoting the charge-separation efficiency and affording abundant catalytically active sites. The excellent selectivity of photocatalytic oxidation of benzyl alcohol on the ultrathin Bi 2 MoO 6 is attributed to the different adsorption behaviors of benzyl alcohol and benzaldehyde. This study could also provide an efficient strategy for improving the photocatalytic performance by rational fabrication of two-dimensional semiconductor materials for organic synthesis.
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TALANTA
·
2016
·
IF 4.035
Shan Shan Miao,Mei Sheng Wu,Li Ya Ma,Xiao Jing He,Hong Yang
A novel and highly sensitive electrochemiluminescence (ECL) biosensing system was designed and developed for individual detection of different organophosphorous pesticides (OPs) in food samples. Bimetallic Pt-Au nanoparticles were electrodeposited on multi-walled carbon nanotubes (MWNTs)-modified glass carbon electrode (GCE) to increase the surface area of electrode and ECL signals of luminol. Biocomposites of enzymes from acetylcholinesterase and choline oxidase (AChE and ChOx) were immobilized onto the electrode surface to produce massive hydrogen peroxides (H 2 O 2 ), thus amplifying ECL signals. Based on the dual-amplification effects of nanoparticles and H 2 O 2 produced by enzymatic reactions , the proposed biosensor exhibits highly sensitivity. The proposed biosensing approach was then used for detecting OPs by inhibition of OPs on AChE. Under optimized experimental conditions, the ECL intensity decreased accordingly with the increase in concentration of OPs, and the inhibition rates of OPs were proportional to their concentrations in the range of 0.1–50 nmol L −1 for malathion , methyl parathion and chlorpyrifos, with detection limit of 0.16 nmol L −1 , 0.09 nmol L −1 and 0.08 nmol L −1 , respectively. The linearity range of the biosensor for pesticide dufulin varied from 50 to 500 nmol L −1 , with the detection limit of 29.7 nmol L −1 . The resulting biosensor was further validated by assessment of OPs residues in cabbage, which showed a fine applicability for the detection of OPs in the realistic sample.
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TALANTA
·
2017
·
IF 4.162
Chi-Fang Peng,Na Pan,Qian Zhi-Juan,Xin-Lin Wei,Guang Shao
In this work, core-shell Au@Pt nanocatalysts (Au@Pt NCs) with ultrathin Pt shell were synthesized and demonstrated high peroxidase-like activity. Thiocyanate ions (SCN - ) were found to effectively inhibit the peroxidase-like activity of Au@Pt NCs, and the mechanism was discussed by the characterization of TEM , DLS, EPR and XPS, etc. The inhibition of the catalytic activity of Au@Pt NCs by SCN - was mainly due to the decreased ability of the Au@Pt NCs for capturing • OH radicals and the increased ratio of Pt 2+ to Pt° on the surface of the Au@Pt NCs. A sensitive colorimetric detection of thiocyanate (SCN - ) was developed, based on the activity inhibition of Au@Pt NCs by SCN - . Interestingly, cystine modification of Au@Pt NCs was found to significantly improve the selectivity of SCN - recognition. After optimization, a colorimetric assay for SCN - was established with a detection limit of 5.0 nM and a broad linear calibration over the range of 20 nM to 40 µM. This assay has the advantages of highly sensitive, selective and low-cost. Moreover, this assay demonstrated highly potential application in the quantitative determination of SCN - in water and raw milk samples.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Long Wu,Wenmin Yin,Xuecai Tan,Pan Wang,Fan Ding,Huan Zhang,Biru Wang,Weiyun Zhang,Heyou Han
It is attractive but remains challenging to develop nanomaterials-based methods to realize the colorimetric detection of ultratrace biological analytes. In this work, an HAuCl 4 -H 2 O 2 system was developed for the visual detection of intracellular hydrogen peroxide (H 2 O 2 ) based on the Au-Pt/SiO 2 sensing platform. Owing to their excellent intrinsic peroxidase-like activity, Au-Pt/SiO 2 nanospheres were introduced to catalyze the decomposition of H 2 O 2 and then directly reduce HAuCl 4 into gold nanoparticles (Au NPs) for the naked-eye detection. The produced Au NPs behaved color variations from light purple to wine red as H 2 O 2 concentration increased. Under the optimal conditions, this strategy showed excellent sensitivity for H 2 O 2 with a detection limit of 0.1 nM by naked-eye readout and 0.1 pM by UV–vis spectrometer (S/N = 3), as well as acceptable selectivity for H 2 O 2 , which could meet the demand for the detection of H 2 O 2 in biological systems. The method was further validated by the determination of H 2 O 2 in HeLa cells with low cellular cytotoxicity. Thus, this strategy would provide simple and sensitive detection of H 2 O 2 in biological systems, revealing the potential application in clinical, biological and environmental researches.
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