RSC Advances
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2026
·Vol. 16
·期 14
·12524-12536
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IF 6.1
Zhaopeng Sun,Yaling Wu,Yingying Chen,Zhibo Li,Sen Lei,Yongyong Cao,Lianwen Zhu,Xuebo Cao,Zheng Yan
Previous studies have often focused on optimizing electrocatalytic performance by altering the type of metal centers or the morphological structure of catalysts to modulate their electronic structures and active sites. However, the precise regulation of metal valence states to enhance catalytic performance—particularly for trifunctional electrocatalysis in the oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evolution reaction (HER)—remains in the exploratory stage. In this study, crystalline Co–N6 materials with controllable valence states were carefully selected as precursors. Through carbonization, Co–N–C materials with similar carbon frameworks but distinct metal valence states (Co2+ and Co3+) were successfully prepared. Both experimental tests and theoretical calculations demonstrate the superior trifunctional electrocatalytic performance of Co2+–N–C. Density functional theory (DFT) calculations provide evidence for the more favorable intermediate adsorption energies and lower reaction energy barriers exhibited by Co2+–N–C. This performance advantage stems from the 3d7 electronic configuration of Co2+, which optimizes electron cloud density and strengthens Co–N bonding interactions. This work presents a new strategy for designing highly efficient electrocatalysts by elucidating the regulatory role of metal valence states.
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Advanced Sustainable Systems
·
2026
·Vol. 10
·期 2
·e01682
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IF 5.6
Handuo Fu,Ke Fang,Shenhui Ma,Lin Wang,Yuyu Bu
In theory, the utilization of a Z-scheme photogenerated carrier transport system has the potential to significantly enhance the photogenerated voltage for photoelectrochemical overall water splitting. However, thus far, there have been no previous reports on such phenomena with silicon-based semiconductor photoelectrodes. In this study, we fabricated an n-Si/Pt/Mo-doped BiVO 4 (Mo: BVO) sandwich-like film with an intermediate carrier transfer layer to prepare a silicon-based photoelectrode with an indirect Z-scheme system. Additionally, by leveraging the lattice distortion effect over Mo: BVO, we increased the fusion ability of the sandwich-like interface between different substances. For the first time, we achieved generation of anodic displacement current via negative voltage (−0.57 V (vs. RHE)), resulting in a photocurrent density of 1.56 mA/cm 2 and a photogenerated voltage five times higher than that of the n-Si/Mo: BVO structure. Through combining experimental approaches with theoretical calculations, it has been confirmed that this realization is attributed to the contribution of the transport process within the Z-scheme system in the n-Si photoelectrode. Furthermore, milliampere-level photocurrent under negative bias was observed for the first time on an n-Si photoelectrode, providing a novel approach for constructing silicon-based photoelectrodes for overall water splitting.
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2026
·
IF 5.9
Shumin Zhang,Li Xu,Yusi Wang,Wenhao Yang,Cheng Zhou,Jianda Xu
Surface biofouling of cotton gauze dressings greatly promotes biofilm formation and delays wound healing. Herein a reversibly thermoresponsive switchable biointerface strategy is proposed to regulate the antibacterial and antifouling activity of cotton dressings for promoting wound healing. Poly(ethylene glycol) (PEG) brushes are covalently grafted onto cotton fibers to form a durable antifouling underlayer, followed by in situ polymerization of poly(N-isopropylacrylamide) (PNI) and subsequent chlorination to generate N-halamine antibacterial groups of N-Cl. In the initial antibacterial state, the outer chlorinated PNI layer releases available active chlorine upon bacterial contact, enabling fast disinfection and efficient biofilm disruption. After chlorine consumption, the PNI recovers its thermosensitive structure and collapses at wound-relevant temperature, exposing the PEG brushes underlayer and switching the interface to an antifouling state. The resulting dressing exhibited rapid and rechargeable antibacterial activity, effective biofilm disruption, excellent biocompatibility, and markedly accelerated healing of infected wounds. This bilayer architecture provides a practical route to reconcile rapid disinfection with sustained antifouling at wound biointerface.
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JOURNAL OF CHEMICAL THERMODYNAMICS
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2026
·
IF 2.5
Dan Li,Xue Meng,Xiazhen Zhang,Fan Yang
The density ( ρ ) and dynamic viscosity ( η ) of ternary system containing n -dodecane, isobutanol and ethyl decanoate and three binary mixtures ( n -dodecane + isobutanol), ( n -dodecane + ethyl decanoate), (isobutanol + ethyl decanoate) were experimentally determined in a temperature range of T = (293.15 to 323.15 K) with a temperature step of 5 K and at pressure 0.1 MPa. The excess molar volume ( V m E ), deviation in viscosity (Δ η ) and excess free energies of activation of viscous flow (Δ G ∗E ) of ternary and the corresponding binary systems were obtained from the ρ and η data. Additionally, Redlich–Kister equation, Cibulka equation and Singh equation were used to estimate V m E and Δ η of ternary mixtures. The V m E exhibites positive values for all binary and ternary mixtures, and the Δ η and Δ G ∗E values are all negative. Achieving a thorough comprehension of biofuel density and viscosity properties is important for researching and developing suitable surrogate fuel mixtures.
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Journal of Environmental Chemical Engineering
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2026
·
IF 7.5
Lixia Wang,Yun Liu,Pengyuan Cui,Dongfang Wang,Qian Li
Interfacial polymerization (IP)-based nanofiltration (NF) membranes often suffer from the permeability–selectivity trade-off due to uncontrolled monomer diffusion and nonuniform polyamide (PA) layer formation. In this work, a g-C₃N₄/polyethyleneimine (PEI) hybrid interlayer was constructed on a polyethersulfone substrate via vacuum-assisted deposition to regulate interfacial polymerization and enhance sulfate separation performance for nanofiltration-related water softening applications. The synergistic interaction between g-C₃N₄ nanosheets and PEI effectively suppressed nanosheet aggregation, enlarged interlayer spacing, and improved interfacial compatibility, thereby promoting the formation of an ultrathin and highly cross-linked PA selective layer. The optimized TFNi-2 membrane exhibited a high water flux of 65.8 L·m⁻²·h⁻¹ together with a Na 2 SO 4 rejection of 96.8% at 0.4 MPa, demonstrating excellent permeability and selective rejection toward multivalent ions. Structural characterizations confirmed that the g-C₃N₄/PEI interlayer regulated amine diffusion behavior and suppressed nonuniform PA formation, resulting in a compact and defect-suppressed selective layer with an MWCO of approximately 600 Da. In addition, the highly permeable interlayer generated a favorable “gutter effect” that reduced transport resistance and facilitated water permeation. The optimized membrane also exhibited satisfactory chlorine resistance and long-term operational stability. This work provides new insights into interlayer-regulated interfacial polymerization for the development of high-performance nanofiltration membranes for sulfate removal and water softening applications.
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APPLIED OPTICS
·
2026
·Vol. 65
·期 14
·4861-4870
·
IF 1.7
Xuefei Xiao,Xuefei Xiao,Xuefei Xiao,Xuefei Xiao,Xingchen Zhou,Xingchen Zhou,Xingchen Zhou,Xingchen Zhou,Zheyuan Gu,Zheyuan Gu,Zheyuan Gu,Zheyuan Gu,Jun Qian,Jun Qian,Jun Qian,Jun Qian,Min Lai,Min Lai,Min Lai,Min Lai,Yan Ma,Yan Ma,Yan Ma,Bo Liu,Bo Liu,Bo Liu,Bo Liu,Bo Liu
This study presents a fiber-optic humidity sensor based on boron and nitrogen co-doped graphene quantum dots (B,N-GQDs). Hydrophilic B,N-GQDs film was fabricated by a hydrothermal method, followed by photo-driven deposition on plastic optical fiber cores. The sensor showed a wide response range (0–85%RH) with high sensitivity (0.0072/%RH), a low detection limit (0.2%RH), high linearity (${R^2} = {0.999}$), and rapid response (2.5 s). The sensor exhibited a low hysteresis and excellent stability. Good stability and promising applications in respiration and skin moisture monitoring were also demonstrated. The sensing mechanism is attributed to humidity-dependent adsorption of water molecules by the abundant hydrophilic groups of the film. This adsorption alters the film’s refractive index and extinction coefficient, modulating the transmitted light intensity via a partial leaky-mode mechanism.
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Inorganic Chemistry Frontiers
·
2026
·
IF 6.2
Yi-Xun Liu,Yu-Ting Xiong,Lin-Dong Wang,Yi-Qi Fan,Liang Wu,Hemdan S. H. Mohamed,Zhi-Yi Hu,Yu Li,Bao-Lian Su
Lithium-selenium (Li-Se) batteries have garnered significant attention recently due to their high energy density. However, selenium cathodes still face challenges such as poor conductivity and severe volume expansion. In this study, we design a novel two-dimensional nitrogen-doped lamellar porous selenium/carbon composite cathode material (Se@NLPC-P) for high performance Li-Se battery. Our results show that the lamellar structure assembled from biomass-derived stacked nitrogen-doped carbon nanosheets, possesses abundant active sites and hierarchical porosity with strong anchoring capability for selenium species. Such a unique structure additionally facilitates electron/ion transfer. Consequently, the Se@NLPC-P cathode retains a reversible capacity of 578 mAh g-1 at 0.5 C after 500 cycles, exhibiting superior rate performance and rapid reaction kinetics. This strategy on design of biomass-derived lamellar porous carbon hosts via a molecular structure-directing provides new insights for enhanced performance of Li-Se batteries.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Xiaowei Zhang,Yanmin Cui,Wei Cheng,Suhong Li,Tuoping Li,Xin Huang
Following modification with APTES, the -NH 2 density reached to 12.04 groups/nm 2 . • Immobilized enzymes showed enhanced stability and broadened optimal reaction range. • Immobilization of LNB synthase by SNPs-NH₂ exhibited positive catalytic modulation. • After 7 cycles, the activity retention rate of the immobilized enzymes was 74–85%. • During 7 cycles of LNB synthesis, the LNB yield was maintained above 90%. Lacto-N-biose (LNB) is the core structural unit of human milk oligosaccharides and plays an indispensable role in the growth and development of infants. In this study, amino-modified SiO 2 nanoparticles (SNPs-NH 2 ) were used as carriers to immobilize sucrose phosphorylase (SPase), UDP-galactose-4′-epimerase (GalE), galactose-1-phosphate uridylyltransferase (GalT), and lacto-N-biose phosphorylase (LNBP), and LNB was synthesized in a one-pot method with high efficiency. The results showed that after activation of SNPs for 16 h at 25 °C with 2 mol/L hydrochloric acid, and modification with 3-Aminopropyltrimethoxysilane (APTES)/SNPs (2:1, v /m) at 65 °C for 9 h, the interface -NH 2 grafting density reached to 12.04 groups/nm 2 . Under the optimal immobilization conditions, the SPase, GalE, GalT, and LNBP were all well-loaded onto the carriers. At the same time, the temperature and pH stability of the enzymes were significantly improved, and the optimal reaction range was significantly expanded. The enzyme activity retention rate after 7 cycles of reaction was 74% to 85%, with the LNB synthesis yield rate remaining above 90%. This study effectively simplified the separation of enzymes from the reaction system during LNB synthesis and improved its stability, laying a foundation for the industrial production of LNB. Download: Download high-res image (107KB) Download: Download full-size image
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ACS Catalysis
·
2026
·Vol. 16
·期 15
·15348-15362
·
IF 13.6
Rhimi Baker,Harrath Karim,Liu Yifan,Liu Zheyang,Zhou Min,El-Khodary Sherif A.,Shi Weidong,Jiang Zhifeng
Photocatalytic CO 2 reduction to C 2 H 4 remains challenging due to inefficient multielectron transfer and sluggish C−C coupling kinetics. Herein, we demonstrate that precise engineering of metal−organic framework (MOF) nodes establishes dual-functional active sites that synergistically drive C−C coupling and H 2 O activation. A hybrid photocatalyst is constructed by integrating a porphyrinic MOF (Fe-MOFBPy), featuring axially coordinated bipyridine ligands that modulate paddlewheel Fe−N nodes, with carbon nitride (CN) to form a heterojunction. Controlled linker depletion introduces defects that generate coordinatively unsaturated Fe sites and enable rational tuning of Fe−N bonding. Combined density functional theory and ab initio molecular dynamics simulations reveal that the Fe−N bond acts as a dual-functional site, where the N atom facilitates H 2 O activation and proton transfer, while the Fe center promotes *CO + *CHO coupling toward C 2 intermediates. In contrast, defective MOFs with reduced Fe−N coordination form Fe−O sites that exhibit inferior activity due to inefficient H 2 O activation. Notably, the intrinsic flexibility of the Fe−N bond lowers the kinetic barrier for H 2 O dissociation. Consequently, the catalyst achieves a C 2 H 4 production rate of 24.5 μmol g −1 h −1 with an 87.1% electron-based selectivity, outperforming analogous systems. This work provides a blueprint for designing dual-functional sites in MOFs for solar-driven C 2 H 4 synthesis.
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Advanced Healthcare Materials
·
2026
·
IF 11
Ming Cheng,Jie Wu,Liru Heng,Yan Liu,Jinyu Yao,Tongtong Zhu,Yongming Zhu,Qiannan You,Zhubing Lei,Tong Wu,Wenfei Dong,Juan Yue,Yuanyuan Qin,Li Li
Glioblastoma (GBM) remains one of the most lethal intracranial malignancies due to its diffuse invasiveness and inevitable recurrence. Sonodynamic therapy (SDT) offers a noninvasive strategy for deep-tissue tumor ablation; however, its efficacy is often limited by rapid electron–hole recombination in conventional sonosensitizers, resulting in insufficient reactive oxygen species (ROS). In this study, a biomimetic nanosonosensitizer is rationally engineered via synergistic type II heterojunction interface construction and Cu─N coordination electronic activation. By anchoring Cu─N coordinated carbon dots (Cu-CDs) onto two-dimensional (2D) nanosheets, the compact heterojunction enables spatial charge separation, while Cu─N motifs act as kinetic promoters to accelerate interfacial electron transfer. This co-engineering strategy markedly enhances ultrasound (US) -triggered multi-ROS generation, leading to amplified oxidative stress. Biologically, intracellular copper overload triggers cuproptosis via lipoylated protein aggregation, whereas ROS burst induces PANoptosis-like cell death. Importantly, the synergistic death programs promote robust immunogenic cell death (ICD) with elevated Damage-associated molecular patterns (DAMPs) release/exposur, thereby activating antitumor immunity and contributing to enhanced therapeutic efficacy against GBM. This work provides new insights into the rational design of highly efficient sonosensitizers and offers new dimensions for precision SDT-based glioma sono-immunotherapy.
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PARASITOLOGY RESEARCH
·
2026
·
IF 1.9
Hou Jiaming,Ruan Rulin,Zhang Ting,Yang Yongqing,Xue Han,Song Mingxin,Han Caixia
In eukaryotes, with the exception of mammals, trehalose fulfills multiple biological functions, including energy provision and stress tolerance. Trehalose-6-phosphate phosphatase (TPP) is a key enzyme in the trehalose biosynthetic pathway, rather than a trehalose synthase per se. Loss of TPP function or knockdown of its expression impairs trehalose synthesis, which in turn leads to developmental abnormalities or lethality in nematodes. These observations suggest that TPP represents a potential target for the development of anti-parasitic therapeutics. This study focused on the cloning, expression, and characterization of Trichinella spiralis TPP (TsTPP). A recombinant plasmid was constructed to express and purify the recombinant TsTPP protein (rTsTPP), whose immunogenicity was confirmed using positive serum from Trichinella spiralis ( T. spiralis )-infected mouse. The expression of TsTPP at different developmental stages of T. spiralis was determined by immunofluorescence assay. The specific TPP inhibitor N-(phenylthio) phthalimide (NPP) was employed to evaluate its lethal effect on T. spiralis muscle larvae (ML) in vitro. Furthermore, molecular methods such as qPCR and Western blot were used to detect the transcription and protein expression levels of TsTPP upon NPP treatment, aiming to identify new drug targets against T. spiralis . We successfully constructed the recombinant plasmid and obtained rTsTPP. Positive serum assays demonstrated the immunogenicity of rTsTPP, and we used indirect immunofluorescence assay (IFA) to determine its localization across different developmental stages of T. spiralis . Distinct distribution patterns were observed: TsTPP was diffusely distributed throughout the body of newborn larvae (NBL), accumulated in the intestinal glands, midgut ampulla and genital primordia of muscle larvae (ML), and localized to the mid and posterior intestine of adult worms (AW). To verify the lethal effect of NPP in vitro, we treated ML with NPP at concentrations of 12.5, 25, 50, 100, and 200 µg/mL for 24, 36, and 48 h, and evaluated its lethal effect by statistical analysis of worm morphology. The experimental results showed that the mortality rate of ML gradually increased with increasing NPP concentration and culture time. When the concentration was 200 µg/mL, the survival rate of ML was less than 50%. Furthermore, when treated with NPP at concentrations of 12.5, 25, 50, 100, and 200 µg/mL for 24 h, the transcription levels of the TsTPP gene decreased by 19%, 23%, 30%, 38% (all p < 0.05), and 57% ( p < 0.01), respectively; after 36 h of treatment, the transcription levels of TsTPP gene were reduced by 18% ( p < 0.05), 23%, 35%, 39%, and 60% (all p < 0.01); after 48 h of treatment, the transcription levels of TsTPP gene decreased by 19%, 23%, 42%, 42%, and 65% (all p < 0.01), respectively. N-(phenylthio) phthalimide (NPP) exhibits significant lethal activity against T. spiralis by inhibiting the trehalose synthesis pathway, providing basic data for future NPP as a new clinical drug target.
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ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Ning-Ya Wang,Yi-Hong Liu,Xiao-Jie Jiang,Hui-Li Guo,Li-Xiao Wang,Bei-Bei Li,Xue Liu,Xiao-Bo Zheng,Jing-Yu Pang,Dong-Bin Dang,Yan Bai
The catalytic activity of single-atom catalysts (SACs) is strongly influenced by their local coordination environment. In this study, a series of Mn-N-C SACs with tunable coordination structures were synthesized via pyrolysis of Mn-doped metal-organic frameworks (MOFs) at different temperatures. High-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) and X-ray absorption spectroscopy (XANES and EXAFS) confirmed the atomic dispersion of Mn and the formation of Mn-N 4 moieties as the active sites. Among the catalysts, Mn-NC-1000°C with high Pyridine-N content exhibited the best performance, achieving a maximum Faradaic efficiency (FE) of 94.9% for CO at –0.47 V vs. RHE in an H-type cell, along with a current density of ∼15 mA . cm −2 . And in a flow cell, the current density increased significantly to ∼100 mA . cm −2 while maintaining high CO selectivity (FE CO =95%) and operational stability (24 h). The density functional theory (DFT) studies further reveal that the Mn-NC-1000°C with high Pyridine-N content effectively reduces the reaction barriers for the formation of *COOH and thus accelerates the reduction of CO 2 .This work provides a controllable strategy for regulating the coordination microenvironment of SACs and offers valuable insights for the development of efficient CO 2 electroreduction system.
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