JOURNAL OF PHYSICAL CHEMISTRY B
·
2011
·
IF 3.603
Panfeng Long,Aixin Song,Dong Wang,Renhao Dong,Jingcheng Hao
The formation of pH-sensitive vesicles and the rheological properties of the mixtures of perfluorolauric acid (PFLA) and its salts (PFL-Na and PFL-Li) neutralized via NaOH or LiOH were investigated in aqueous solution. When the right mixing ratios of the ionized to nonionzed PFLA molecules with a very high Krafft point are established, vesicles can spontaneously form at room temperature. The vesicles spontaneously formed in the PFLA/PFL-Na/H2O system with the rigid fluorocarbon chains were determined by atomic force microscopy images. Compared to those of hydrocarbon amphiphiles, these vesicle samples, which can be kept for 2 years at room temperature, are more stable. The phase transition from the vesicle phase to the lamellar lyotropic liquid crystal phase with the increase of pH was determined by freeze-fracture transmission electron microscopy images in the PFLA/PFL-Li/H2O system. The system of perfluoro fatty acid vesicles exhibits much more interesting rheological properties, compared to hydrocarbon fatty acid vesicles. The perfluoro fatty acid vesicle solutions display a much higher yield stress and viscoelastic properties, which depend on two factors: (i) the fluorinated alkyl chains of PFL–, which are in the crystalline state at room temperature because of their rigid chains compared to analogous hydrocarbon chains, and (ii) the packing of the vesicles, which is very dense. This is the first time that pH-sensitive vesicles exhibiting birefringence were constructed through ionizing perfluoro fatty acid, which may direct primarily toward acquiring an understanding of the mechanism of vesicles depending on the right mixing ratios of the ionized to the nonionzed perfluoro fatty acid molecules with a very high Krafft point and secondarily to expand the development of fluorinated surfactants in both fundamental research and practical applications.
✓ 已验证
DOI
高影响因子
WATER SCIENCE AND TECHNOLOGY
·
2022
·Vol. 85
·期 7
·2051-2064
·
IF 2.43
Jiang Qihui,Qian Ruyi,Shen Tongdong,Tong Shaoping
Graphite felt (GF) supported cerium oxide (CeO 2 ) composite with sulfation pretreatment (H 2 SO 4 -CeO 2 /GF) was prepared by the impregnation method and employed as the catalyst to activate H 2 O 2 for degradation of isoniazid (INH). The obtained samples were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and X-ray photoelectron spectrum (XPS). The results showed that H 2 SO 4 -CeO 2 /GF had good properties in activating H 2 O 2 for the degradation of INH. The INH removal was about 89.4% in 120 min under the following conditions: H 2 O 2 2.94 mM, H 2 SO 4 -CeO 2 /GF 2.6 g/L, INH 10 mg/L, initial pH at 6.8 and temperature at 25 °C. The effects of some reaction parameters, including initial H 2 O 2 concentration, initial INH concentration, initial pH value, the catalyst dosage and reaction temperature, on INH degradation were investigated. On the basis of mechanism study and intermediate analysis, the possible degradation pathway of INH was proposed. Besides, effective degradation of methyl orange (MO) and norfloxacin (NOF) also confirmed the high activity of H 2 SO 4 -CeO 2 /GF in activation of H 2 O 2 . The H 2 SO 4 -CeO 2 /GF was relatively stable, showing good application prospects. Acidified cerium oxide/GF composite (H 2 SO 4 -CeO 2 /GF) was prepared by impregnation. The activity of H 2 SO 4 -CeO 2 /GF for activation of H 2 O 2 is high even at pH 7.0. The catalyst of H 2 SO 4 -CeO 2 /GF is stable and has great potential for application. The role of acidification of sulfuric acid in the catalyst is explained.
✓ 已验证
DOI
高影响因子
COLLOID AND POLYMER SCIENCE
·
2014
·Vol. 292
·期 9
·2071-2082
·
IF 2.41
Fu Yutong,Xia Xinyu,Zhang Yan,Ye Jinhai,Lang Meidong
Functional star-shaped 4-arm poly(ethylene glycol)- b -poly[( ε -caprolactone- co - γ -amino- ε -caprolactone)] (4-arm PEG- b -P(CL- co -ACL) was synthesized through ring-opening polymerization. The structure of the copolymer was confirmed by 1 H NMR, Fourier transform infrared spectroscopy (FTIR), and gel permeation chromatography (GPC). To further understand the copolymers, the difference of the conversion rate between ε -caprolactone (CL) and γ -(carbamic acid benzyl ester)- ε -caprolactone (CABCL) and the detailed deprotection condition were studied. The thermal property of the copolymer was analyzed by WAXR and differential scanning calorimetry (DSC), which demonstrated that the thermal property could be well adjusted. The pH-responsive behavior of the copolymers was studied in detail by dynamic light scattering (DLS), pH titration, and pyrene fluorescence methods, which indicated that it could form micelles and exhibit pH responsibility. Moreover, the copolymer was nontoxic and had good biocompatibility according to the results by 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di-phenytetrazoliumromide (MTT) assay.
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Junxiang Pei,Haofeng Li,Fayi Chen,Zitao Chen,Xiaodong Yuan,Zhaoxia Han,Daqin Chen,Dechao Yu,Dawei Zhang
Carbon quantum dots (CQDs) with fluorescence emission have been widely studied for versatile applications, but facile tunability of the spectral properties of CQDs by doping remains to be further explored. Herein, employing lanthanide ion Eu3+ as a dopant and activator, a simple and efficient synthesis route for pure CQDs and Eu-CQDs was demonstrated using N, N-dimethylformamide, oleic acid, and oleylamine as precursors for carbon sources. In comparison, with the popular citric acid precursor, the as-prepared CQDs and Eu-CQDs exhibited an obviously smaller particle size (1.72 ± 0.29 nm) and a more uniform distribution. Through systematic optimization of Eu3+ doping for the Eu-CQD system, colorful light emissions in the visible range were first realized under excitation of ultraviolet (UV) ∼360 nm for promising application of UV-triggered light-emitting diodes. Most interestingly, this Eu-CQD solution with UV-excited colorful light emissions was utilized as a visual pH sensor, experimentally featuring good repeatabilities and stabilities (pH values switching between 7 and 14). Besides, the Eu-CQD solution exhibited highly sensitive detection characteristics for Co (II) ions. Due to the spectral overlapping, the quenching efficiency is as high as 96.3%, and the detection limit is obtained as 0.139 μM, which is much lower than the maximum concentration of Co (II) in the drinking water permitted by WHO. All of these relevant results significantly demonstrate the great potential of lanthanide doping in the multifunctionalization of CQDs for certain emerging applications like lighting, sensing, and detection.
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Xiaolu He,Yanbao Zhao,Yuting Zhang
Smart environment-responsive nanopesticides offer significant potential to improve foliar retention and utilization efficiency. We developed a pH/temperature dual-responsive platform (DNF@PSP@AL) using spiky, pineapple-like silica/poly- dopamine nanocarriers and Fe³ ⁺-alkaline lignin for dinotefuran delivery. The nanocarriers' unique morphology enabled strong foliar adhesion. DNF@PSP@AL achieved 25 % loading capacity. The Fe³ ⁺-AL coating acted as a photoresponsive barrier, conferring exceptional UV stability (UV half-life over 10 times that of commercial formulations) and superior rainfall resistance (14 % washout vs. 72 % conventional). The DNF@PSP@AL demonstrated high control efficacy against Plutella xylostella . This work presents a novel nanoformulation strategy enhancing pesticide efficiency and minimizing environmental loss through intelligent, adhesion-promoting design.
✓ 已验证
产品关联
DOI
高影响因子
DALTON TRANSACTIONS
·
2025
·
IF 3.3
Lihua Wang,Xionghongcan Zhou,Zengyu Ye,Sha Li,Yayang Wu,Kaiyue Song,Feng Zhao,Xianglong Li
Developing smart nanosystems that integrate controlled drug release with gas therapy represents a promising strategy to enhance chemotherapeutic efficacy while minimizing systemic toxicity. Herein, we report a biodegradable in-situ hydrogen sulfide (H2S) nanogenerator based on ZnS nanoparticles (NPs) for pH-responsive co-delivery of H2S and doxorubicin (DOX). ZnS NPs were synthesized via a rapid hydrothermal method and subsequently functionalized with hyaluronic acid (HA) to form ZnS@HA, which was then electrostatically loaded with DOX to yield ZnS@HA-DOX NPs. The nanosystem maintains structural integrity under physiological conditions (pH 7.4) but selectively releases both DOX and H2S under acidic tumor microenvironment (pH 5.0), as confirmed by fluorescence spectroscopy, lead acetate paper assays, and WSP-1 probe-based quantification. In vitro studies using 4T1 breast cancer cells revealed that ZnS@HA-DOX NPs exhibit significant cytotoxicity compared to ZnS@HA NPs alone, indicating a synergistic effect between H2S gas therapy and chemotherapy. This work demonstrates the potential of ZnS-based nanogenerators as a multifunctional platform for pH-triggered, site-specific, and synergistic cancer therapy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PEST MANAGEMENT SCIENCE
·
2025
·Vol. 82
·期 2
·1629-1641
·
IF 3.8
Yuying Xie,Yangchun Ge,Zhuochao Shen,Yupeng Qiu,Honglei Wang,Haohua Zhang,Qingyue Zhang,Tingting Xiang,Minhui Wo,Xuqiang Peng,Zhongyu Li
BACKGROUND The development of efficient and environmentally friendly herbicide-delivery systems is crucial in modern agriculture. Such systems can achieve precise targeting and controlled release of active ingredients through formulation technologies like slow-release carriers and targeted microcapsules. This study aims to synthesize a novel bio-based polymer through polycondensation of the natural product honokiol with triethylene glycol divinyl ether, and to evaluate its potential as a herbicide carrier. RESULTS This study successfully synthesized an amphiphilic honokiol-based polymer. The resulting polymer micelle suspension, formed via self-assembly, exhibited a particle size of 130.5 nm, a critical micelle concentration of 3.8 × 10 −3 mg/mL, a drug loading capacity of 13.79%, and an encapsulation efficiency of 82.75%. In vitro release studies demonstrated pH-dependent kinetics, with 80.1% cumulative release of diuron at pH 5.0 over 60 h, compared with only 16.35% at pH 7.0. Herbicidal activity tests against Echinochloa crus-galli demonstrated that the polymer micelle suspension achieved higher mortality rates and fresh weight reduction than diuron dispersion systems, attributable to their rhizosphere-triggered release properties, while significantly enhancing crop seedling safety. CONCLUSIONS This study represents the first successful application of honokiol-based polymers in the field of herbicide delivery. The carrier system exhibits excellent controlled-release properties and synergistic effects, significantly enhancing herbicide utilization efficiency while reducing potential environmental risks. These findings provide a promising strategy and material foundation for developing a new generation of green pesticide formulations. © 2025 Society of Chemical Industry.
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Xiaoyan Liu,Yang Li,Changjing Qiu,Zhongming Liu,Shoujuan Wang,Fangong Kong
Conventional drug delivery systems often face challenges such as low biocompatibility, and limited effectiveness; thus, developing sustainable, pH-responsive materials like carboxylated cellulose nanofibrils (CNF) can enhance drug delivery efficacy. In this study, carboxylated CNF was used as raw materials, acrylic acid (AA) was used as a pH-responsive monomer, and a pH-responsive CNF composite aerogel was constructed as a drug carrier using free radical polymerization and physical blending. The microstructure and physicochemical properties of the CNF composite aerogels before and after drug loading were analyzed using advanced technologies including Fourier-transform infrared (FTIR), thermogravimetric analysis (TGA), x-ray diffraction (XRD), elemental analysis, scanning electron microscopy (SEM), and pore size analysis. The introduction of graphene oxide (GO) modified and optimized the network structure of cellulose aerogels and increased the drug-loading capacity. The network structure formed by AA polymerization made the network structure of the CNF composite aerogel more compact and uniform and prolonged the drug-release time. The loading capacities of the CNF-GO-5-FU, CNF-AA-5-FU, and CNF-AA-GO-5-FU CNF composite aerogels for fluorouracil were 286.78, 275.35, and 312.64 mg/g, respectively. The release curve of the CNF composite aerogel demonstrated a pH response that conformed to the first-order kinetics, Higuchi, and Korsmyer–Peppas models. The sustained-release mechanism of the CNF composite aerogel followed the Fickian diffusion mechanism, highlighting the aerogel's strong biomedical application potential.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2026
·
IF 4.6
Qingmei Zhong,Xiaomei Rong,Jiayi Liu,Huixiang Zong,Chuan Yan
The detection of pH and nitroreductase (NTR) in tissues plays a crucial role in assessing microenvironmental acid-base balance and diagnosing tumor hypoxia. However, most methods currently used for detecting substances in tissue samples require sample grinding for extraction, which compromises tissue integrity. Traditional Chinese medicine acupuncture needles offer a potential approach as they can be directly inserted into tissues, eliminating the need for destructive pretreatment procedures. In this work, we developed a novel acupuncture needles @ gold nanoparticles @ 5-mercapto-2-nitrobenzoic acid (ANs@Au NPs@MNBA) probe based on surface-enhanced Raman spectroscopy (SERS) technology, enabling simultaneous ratiometric detection of pH and NTR in both solution and intact tissue samples. The probe demonstrated excellent linear responses within pH ranges from 4.75 to 7.25 and NTR concentrations from 0 to 20.0 μg/mL. This innovative approach provides valuable insights into how tissue acid-base balance and NTR levels influence physiological functions and disease progression.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Yang Liu,Weitao Li,Zhongyan Lu,Haoyang Cai,Ruiling Yuan,Yongqi Yang,Xuezhi Qiao
Monitoring biomarkers in interstitial fluid (ISF) offers a compelling alternative to blood analysis for managing chronic metabolic diseases, owing to the high correlation between ISF and blood analyte concentrations. Herein, we reported a biomimetic microneedle (MN) sensor based on Surface-Enhanced Raman Scattering (SERS) for the minimally invasive, simultaneous detection of pH and uric acid (UA). The sensoring platform functionalized with a plasmonic active interface, constructed via the in situ self-assembly of gold nanoparticles (AuNPs). Crucially, this dense AuNP layer serves a dual function: it creates high-density SERS “hot spots” for signal amplification and significantly improves surface hydrophilicity, thereby facilitating the efficient extraction and enrichment of analytes from the ISF matrix. The sensor displayed superior analytical performance for dual UA and pH detection, offering broad linear dynamic ranges and suitable monitoring intervals relevant to physiological conditions. Additionally, this sensor displayed remarkable durability and reusability, successfully completing penetration and signal acquisition in a simulated skin environment. This work presents a robust, multifunctional sensing strategy for the minimally invasive management of gout and other metabolic disorders, paving the way for future in vivo applications.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2015
·Vol. 133
·期 15
·
IF 1.768
Mi Zhou,Kaiyue Liu,Xin Qian
A series of pH-temperature dual stimuli-responsive random copolymers poly[ N,N -dimethylaminoethyl methacrylate- co -poly(poly(ethylene glycol) methyl ether methacrylate][poly(DMAEMA- co -MPEGMA)] were synthesized by free radical polymerization. The supramolecular hydrogel was formed by pseudopolyrotaxane, which was prepared with the host-guest interactions between α-cyclodextrin (α-CD) and poly(ethylene glycol) (PEG) side chains. Fourier transform infrared (FT-IR), nuclear magnetic resonance ( 1 H NMR), and X-ray diffraction (XRD) confirmed the structures of the hydrogels. The pH-temperature dual stimuli responsive properties of the hydrogels were characterized by rheometer. Finally, the controllable drug release behavior of the hydrogel, which was used 5-fluorouracil (5-Fu) as the model drug, was investigated at different temperatures and different pH values. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133 , 43279.
研究领域:
高分子材料科学
·
药物递送系统
·
生物医学工程
·
智能响应材料
·
药剂学
✓ 已验证
DOI
高影响因子
ACS Earth and Space Chemistry
·
2019
·
IF 2.243
Zong-Sheng Liang,Bao-Dong Song,Yong-Ling Liu,Yong Liu,Hai-Tao Ren,Song-Hai Wu,Shao-Yi Jia,Xu Han
Natural pyrite has a strong ability to immobilize Ni(II) impurities. However, the differences in the oxidation reactivity between Ni(II)-adsorbed pyrites [Py*-Ni(II)] and Ni(II)-structurally incorporated pyrites [Py-Ni(II)] are still not clearly understood. In this study, Ni(II)-free pyrite (Py-free), Py*-Ni(II), and Py-Ni(II) were prepared, and their oxidation reactivity were compared. Our results show that Ni(II) can be successfully incorporated into the crystalline structure of Py-Ni(II) by replacing structural Fe(II) with the formation of sulfur defects on the surface of Py-Ni(II). The oxidation reactivity of different pyrites depends on how Ni(II) is immobilized in pyrite and follows the order of Py-0.08 > Py-0.02 > Py-free > Py*-Ni(II) [Py-0.02 and Py-0.08 are named according to the Ni(II):Fe(II) molar ratios in the starting material for the synthesis of Py-Ni(II)], indicating that structurally incorporated Ni(II) enhances the oxidation rate of pyrite, whereas adsorbed Ni(II) does the opposite. Differences in the electrochemical properties also indicate that structurally incorporated Ni(II) enhances the electron-transfer rates at the Py-Ni(II) surface, thus increasing the oxidation rates of pyrite. Variations in H2O2 concentrations confirm that the high electron-transfer rates induced by structurally incorporated Ni(II) enhance the reaction rates between dissolved oxygen and the pyrite surface, producing H2O2 at pHs 2.5 and 7.0. The presence of Fe(III)-S(-II) defects also significantly contributes to the production of H2O2. Variations of cumulative ·OH indicate that structurally incorporated Ni(II) improves the production of ·OH at pHs 2.5 and 7.0. The significantly higher concentrations of ·OH than those of H2O2 at pH 2.5 indicate that ·OH plays an important role in pyrite oxidation under acidic condition. The comparable concentrations of H2O2 and ·OH at pH 7.0 suggest that H2O2, ·OH, and even Fe(IV) formed between pyrite and H2O2 contribute to pyrite oxidation under pH-neutral condition.
研究领域:
环境化学
·
地球化学
·
矿物表面科学
·
氧化过程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）