CHEMOSPHERE
·
2020
·
IF 5.778
Yifei Leng,Henglin Xiao,Zhu Li,Ying Liu,Jun Wang
Enzyme catalyzed coupling with redox mediators are considered as great interesting and viable technologies to transform antibiotics. This work demonstrated the horseradish peroxidase (HRP) was effective in transforming sulfadiazine (SDZ) transformation coupled with 1-hydroxybenzotriazole (HBT) at varying conditions. The removal of SDZ was independent of Na + and its ionic strength, but Ca 2+ could enhance transformation efficiency by increasing the enzyme activity of HRP. The presence of humic acid (HA) and polystyrene (PS) microplastics showed inhibition on the transformation of SDZ, and the transformation rate constants ( k ) decreased with the concentration of HA and PS particles increased. These primarily attributed to covalent coupling and electrostatic interaction between SDZ and HA, SDZ and PS, respectively, which reduced the concentration of free SDZ in the reaction solution. The presence of cation recovered the inhibition of SDZ transformation by HA and PS particles, which ascribed to compete between cation and SDZ. The divalent cations (Ca 2+ ) showed more substantial competitiveness than mono (Na + ) due to more carried charge. Eight possible transformation products were identified, and potential SDZ transformation pathways were proposed, which include δ-cleavage, γ-cleavage, carbonylation, hydroxylation, SO 2 extrusion and SO 3 extrusion. In addition, HA and PS particles couldn’t affect the transformation pathways of SDZ. These findings provide novel understandings of the transformation and the fate of antibiotics in the natural environment by HRP coupled with redox mediators.
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高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2024
·
IF 4.1
Youbing Zhu,Ketao Shi,Tao Zhang,Nianming Jiao,Hui Wang
One-dimensional microporous zeolite, EU-1, exhibits more favorable selectivity of propylene in cracking of petroleum components. However, it faced the problem of low catalytic activity for the poor utilization of active sites. In this work, dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (TPOAC) was used to functionalize protozeolitic units and inhibit the excessive growth of crystals by the long hydrophobic alkyl chain. The introduction of TPOAC decreased the crystal sizes into nanoscale, enhanced the mesoporous volume of EU-1 zeolite, and exposed more external acid sites. Moreover, TPOAC could interact with Al species, and in this case, fewer Al atoms were incorporated into the zeolite framework, reducing the acid strength and amount. Intelligent gravitation analyzer test indicated that the zeolite prepared with the presence of 0.30 g TPOAC exhibited the largest accessible volumes in n-hexane adsorption, and the highest accessibility of acid sites, which synergistically promoted cracking of n-hexane for the production of light olefins.
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AAPS PHARMSCITECH
·
2024
·Vol. 25
·期 7
·1-15
·
IF 3.4
Shi Feng,Gong Mingjie,Adu-Frimpong Michael,Jiang Xia,Wang Xiaowen,Hua Qinyang,Li Tingyuan,Li Jiaying,Yu Jiangnan,Toreniyazov Elmurat,Cao Xia,Wang Qilong,Xu Ximing
In this study, N, N '-bis {4- [(α-L- rhamnosyloxy) benzyl]} thiourea (PG-1), a phenolic glycoside compound was purified from Moringa seed. The PG-1 has attracted extensive attention due to its anti-cancer, antioxidant, anti-inflammatory and hypoglycemic properties. However, some of its physicochemical properties such as oral bioavailability has not been studied. Herein, a highly purified PG-1 was extracted and incorporated in multiple layered liposomes (PG-1-L) to avoid its burst release and enhance oral bioavailability. After appropriate characterization, it was discovered that the obtained PG-1-L was stable, homogeneous and well dispersed with the average particle size being 89.26 ± 0.23 nm. Importantly, the in vitro release and in vivo oral bioavailability of PG-1-L were significantly improved compared with PG-1. In addition, MTT results showed that compared with the free PG-1, PG-1-L displayed obvious inhibitory effect on the HepG2 cells, while the inhibitory effect on healthy non-malignant 3T6 and LO-2 cells was not significant, indicating that PG-1-L had high safety. In conclusion, PG-1-L can be used as a promising delivery system and an ideal novel approach to improve the oral bioavailability and anticancer activity of PG-1. Graphical Abstract
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ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Xin Li,Longxun Teng,Yening Ren,Rui Liu,Xiaoyuan Zhan,Haiqing Sun,Weiwei Zhang,Jianxu Ding,Huiling Zhu
Metal halide perovskite CsPbI3 quantum dots (QDs) have sparked widespread research due to their intriguing optoelectronic. However, the CsPbI3 QDs undergo inevitable aging and luminescence quenching caused by the weak binding ability of oleate (OA–)/oleylammonium (OAm+), hindering further practical application. Herein, we have realized ultrafast rejuvenation of the aged CsPbI3 QDs that have lost their photoluminescence performance based on a 1-dodecanethiol (DDT) surface ligand to restore the outstanding red light emission with a high photoluminescence quantum yield (PLQY) from 25 to 90%. Furthermore, CsPbI3 QDs with DDT surface treatment maintain a cubic phase and high PLQY value even after 35 days. The DDT ligands can form a strong bond with Pb2+ and passivate I– ion vacancies, enhancing radiative recombination efficiency and thereby improving the PLQY of the QDs. The stable yet easily accessible surface of the DDT-capped CsPbI3 QDs was successfully employed as white LEDs and exhibited considerable enhanced luminous performance, suggesting promising application in solid-state lighting fields.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Wenjie He,Wei Xu,Zhigang Li,Yansheng Sun,Jingzeng Gu,Xinxin Cao,Kangsheng Huang,Min Zhang,Jiangmin Jiang
The large-scale development of low-cost silicon monoxide (SiO) anode is limited due to its low initial Coulombic efficiency (ICE) and poor cycle stability. Herein, the Ge x SiO (1-x) (0
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JOURNAL OF POWER SOURCES
·
2020
·
IF 8.247
Ning An,Zhuhang Shao,Zhen Guo,Jiao Xin,Yuanyuan He,Liwen Lv,Kefeng Xie,Xiuyan Dong,Yang Zhang,Zhongai Hu
In this work, we select a novel multi-redox poly (1, 5-diaminoanthraquinone) (PDAAQ) as electroactive material and Cetyltrimethylammonium bromide (CTAB) modified graphene oxide (CGO) as conductive substrate. Benefit from the excellent dispersion of CGO in organic polymerization medium and the abundant functional groups on the surface of CGO, 1, 5-diaminoanthraquinone (DAAQ) monomers may covalently graft on the conducting substrates and realize the directional growth of PDAAQ via the in-situ chemical oxidative polymerization. In three-electrode system, the optimization of PDAAQ/CGO electrode exhibits a high specific capacitance of 760 F g −1 at 1 A g −1 and superior electrochemical stability of 90.4% after 10 000 cycles. Most importantly, the electrochemical kinetic behavior of PDAAQ/CGO electrode is studied in detail. The result indicates that the energy storage process of PDAAQ/CGO is a synergistic result of diffusion-controlled process and capacitive effects, and the latter one is dominant. According to the simulation calculation of kinetic model , the capacitive contribution ratio of PDAAQ/CGO can be as high as 80.6% at a scan rate of 50 mV s −1 . Finally, the as-fabricated asymmetric supercapacitor (ASC) can deliver an energy density up to 41.1 W h kg −1 at a power density of 1000 W kg −1 , indicating a great potential application in high performance supercapacitors .
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Frontiers of Chemical Science and Engineering
·
2024
·Vol. 18
·期 2
·1-13
·
IF 4.3
Zhang Feng,Xu Shuainan,Geng Xiumei,Shan Meixia,Zhang Yatao
Polymers of intrinsic microporosity shows great potential for dye adsorption and magnetic Fe 3 O 4 are easy to be separated. In this work, hydrolyzed polymers of intrinsic microporosity-1/Fe 3 O 4 composite adsorbents were prepared by phase inversion and hydrolysis process for cationic dye adsorption. The chemical structure and morphology of the composite adsorbents were systematically characterized by several characterization methods. Using methylene blue as the target dye, the influences of solution pH, contact time, initial dye concentration, and system temperature on the methylene blue adsorption process were investigated. The incorporation of Fe 3 O 4 particle into hydrolyzed polymers of intrinsic microporosity-1 endow the adsorbent with high magnetic saturation (20.7 emu·g −1 ) which allows the rapid separation of the adsorbent. Furthermore, the adsorption process was simulated by adsorption kinetics, isotherms and thermodynamics to gain insight onto the intrinsic adsorption mechanism. In addition, the composite adsorbents are able to selectively adsorb cationic dyes from mixed dyes solution. Hydrolyzed polymers of intrinsic microporosity/Fe 3 O 4 shows only a slight decrease for methylene blue adsorption after 10 adsorption/regeneration cycles, demonstrating the outstanding regeneration performance. The high adsorption capacity, outstanding regeneration ability, together with simple preparation method, endow the composite adsorbents great potential for selective removal of cationic dyes in wastewater system.
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Current Computer-Aided Drug Design
·
2024
·
IF 1.5
Na An,Dongxing Zhang,Jile Xin,Xinyi Zhang,Zhijuan Zhang,Ligang Ma,Le Zhao,Huimin Wu,Weisheng Feng,Xiaoke Zheng
Background: Si-Ni-San (SNS) is the formula prescription of Traditional Chinese Medicine (TCM) with anti-depression properties, but its underlying mechanisms remain unclear. Objective: This study provides novel approaches for the study of Traditional Chinese Medicine (TCM) and offers new opportunities for exploring the pharmacological properties of SNS. Methods: The ingredients in SNS implicated in the treatment of depression were identified and studied using network pharmacology. SwissTargetPrediction and molecular docking were used to study the interaction of SNS ingredients and their targets. The protective effect of these ingredients and their cocktail in rat pheochromocytoma cells (PC12) exposed to corticosterone (Cor) were evaluated using the CCK-8 assay, Hoechst 33342 staining, 2',7'-dichlorodihydro fluorescein diacetate (H2DCFDA) staining, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, and in-cell Western analysis. Results: The network pharmacology study showed that the HIF-1 signaling pathway was the most crucial pathway implicated in the anti-depressive property of SNS. MAPK1 (ERK2), MAPK3 (ERK1), AKT1, VEGFA, STAT3, and EGF were identified as hub target proteins in the HIF-1 signaling pathway. Quercetin, naringenin, licochalcone A, and kaempferol from SNS, which targeted the six proteins mentioned above, were used to create a cocktail. This cocktail exerted protective properties, decreased the oxidative stress in PC12 exposed to Cor, and successfully regulated the expressions of AKT1, p-AKT1, ERK1, ERK2, p-ERK1/2, STAT3, p- STAT3, and VEGFA induced by Cor exposure. The SwissTargetPrediction and molecular docking study showed that the cocktail may regulate the HIF-1 signaling pathway by directly binding with AKT1 and MAPK1. Conclusion: The cocktail from SNS comprised of quercetin, naringenin, licochalcone A, and kaempferol exerts anti-depression potentiality by modulating the HIF-1 signaling pathway via direct interactions with AKT1 and MAPK1.
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PubMed
高影响因子
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
·
2023
·Vol. 48
·期 12
·16471-16482
·
IF 2.9
Zainuddin Muhd Izzudin Fikry,Ahmad Abdul Latif,Subramaniam Reasmyraj R.
Carbon dioxide (CO 2 ) separation with membrane technology has become the focus of researchers over the past decades due to its lower energy consumption and cheaper alternative. Mixed matrix membrane (MMM) of poly(4-methyl-1-pentene) (PMP) with nano fumed silica particles was studied to determine the feasibility of using MMM to separate CO 2 from nitrogen (N 2 ) gas. The critical concentration of PMP (7 wt%) was utilized to form the membrane in this study in order to ensure the polymer chain entanglement occurs to form a dense structure. Agglomeration of particle can be observed on the surface with scanning electron microscopy (SEM) imaging with 10 and 15 wt% of nano fumed silica loading in PMP matrix. This observation is further confirmed with energy-dispersive X-ray (EDX) mapping across the cross-sectional area which shows clustered nano fumed silica particle with loading of 10 and 15 wt%. With 7.5 wt% filler loading and at 1 bar, the MMM seems to give the best gas permeance performance with CO 2 permeance of 4.62 GPU (100.54 Barrer) and N 2 permeance of 0.20 GPU (4.31 Barrer) which makes the highest ideal selectivity to be about 23, which was the highest ideal selectivity achieved in this study. Meanwhile, when the pressure was increased from 1 to 7 bar, the CO 2 permeability increased almost linearly followed by a steady decline in CO 2 /N 2 ideal selectivity.
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CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Yuyu Liu,Wenye Deng,Xianghui Chen,Yan Xue,Xuelian Bai,Pengjun Zhao,Huimin Zhang,Aimin Chang,Yongxin Xie
The perovskite CaMn x Zr (1- x ) O 3 ( x = 0, 0.05, 0.10, 0.15) (CMZO) NTC (Negative Thermal Coefficient) thermo-sensitive ceramic were prepared by the solid phase method that can be used as high temperature thermistor materials in the range of 200–1200 °C.The XRD pattern showed that CMZO is a finite solid solution and that a second phase, CaMnO 3 , will be formed after exceeding the solid solution limit (i.e., at x = 0.1). The thermal constant B value was found to decrease from 19521 K to 9217–9535 K, with a corresponding decrease in activation energy , E a , from 1.69 eV to 0.82 eV. The Nyquist plot indicates that the grain boundary resistance determines the overall complex impedance. Moreover, the aging drift rate (ΔR/R 0 ) was found to be lower than 4.3%, which is an indication of an excellent high temperature stability of the CMZO ceramic material.
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高影响因子
Science China-Chemistry
·
2013
·Vol. 57
·期 3
·397-401
·
IF 1.327
Zhang QiBo,Hua YiXin,Wang Rui
Direct electroreduction of solid cuprous chloride to prepare copper powder in a “neutral” ambient-temperature ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate ionic liquid (BMIMBF 4 ) was investigated. Cyclic voltammetry of the CuCl powder in a Pt-powder cavity microelectrode exhibited that solid CuCl can be electrochemical reduced in the ionic liquid. Chronoamperometry of the salt powder filled Mo-cavity electrode (current collector) in the ionic liquid further demonstrated the conversion of chloride-to metal inside the cavity, as confirmed by scanning electron microscopy, energy-dispersive X-ray, and X-ray diffraction spectra.
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TRANSITION METAL CHEMISTRY
·
2017
·Vol. 42
·期 4
·273-283
·
IF 1.358
Fang Dong-Lin,Mo Shao-Yin,Wu Kai-Fei,Huang Zhong-Jing
Three coordination polymers have been obtained by hydrothermal synthesis, namely [Zn(imip)(H 2 O) 2 ]·0.5H 2 O ( 1 ), [Co(imip)(H 2 O) 2 ]·0.5H 2 O ( 2 ), and [Cd 2 (imip) 2 (H 2 O) 3 ] ( 3 ) [H 2 imip = 5-(1H-imidazol-1-yl) isophthalic acid]. The coordination polymers were characterized by IR spectra, elemental analysis, powder X-ray diffraction, and thermogravimetric analysis. Furthermore, single-crystal X-ray analysis reveals that they have 2D structures, which are extended into 3D networks via O–H···O hydrogen-bonding interactions. The luminescent properties of these coordination polymers were investigated.
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