SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Mengying Lin,Jingyu Zhu,Zhaoyang Qi,Jie Chen,Changshen Ye,Ting Qiu
Amino acid spacer-regulated Zr W synergy yields a volcano-like activity trend. • UiO-0.3GABAPW enables complete sulfur removal in 15 min at RT with O/S = 2. • Stable GABA anchoring sustains 100% sulfur removal over 9 consecutive cycles. In order to meet the trend of sulfur-free fuels, it is of great significance to construct catalysts with high-efficiency oxidant activation ability for deep desulfurization at room temperature and low sulfur ratio. In this study, based on the synergistic catalysis of Zr site and W site double active centers in PW/UiO-66, HPW was encapsulated in the main body of UiO-66 by using amino acids with different carbon chain lengths as bridging molecules. The defect-rich catalyst was synthesized by manual grinding method to achieve efficient extraction-catalytic oxidation desulfurization at room temperature. By adjusting the carbon chain length of linear amino acids, the dispersion state of HPW in UiO-66 was optimized, the electron transfer rate between them was improved, and the synergistic effect of Zr W dual active centers was fully utilized. EPR and in-situ infrared characterization showed that hydroxyl radicals and superoxide radicals were generated at the Zr site during the reaction, and the free radicals were converted into tungsten peroxide active oxygen intermediates during the oxidative desulfurization (ODS) process. The regulation of amino acids makes the synergistic effect of Zr W active sites play a full role, which makes the catalyst have excellent catalytic performance. In the ODS system, complete desulfurization (100% removal efficiency) is achieved under mild conditions: ambient temperature, O/S molar ratio of 2, catalyst loading of 1.5 wt%, and a reaction time of 15 min. Furthermore, the catalyst retains nearly unchanged desulfurization performance over nine consecutive ODS cycles, confirming its outstanding reusability. These research results establish a structure–activity foundation for the rational design of highly active, room-temperature deep desulfurization catalysts. Download: Download high-res image (442KB) Download: Download full-size image
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Energy & Environmental Materials
·
2026
·
IF 13.8
Fujuan Wang,Nan Jia,Tianyun Zhang,Xiaoya Kang,Rui Wang,Fen Ran
The performance of hard carbon anodes in sodium-ion batteries is restricted by the inherent trade-off between rate capability and capacity due to uncoordinated ion-electron transport. This research indicates that the microstructure of the carbon host crucially determines the interfacial reconstruction behavior and electrochemical outcome of MOF modification. For porous cellulose-derived carbon, the integration of MOF induces a continuous composite interface, enhancing the Na + diffusion coefficient by an order of magnitude below 0.1 V (reaching 10 −9 cm 2 s −1 ), and yielding a high reversible capacity of 667.2 mAh g −1 with 79% capacity retention. In contrast, on commercial hard carbon with a higher degree of graphitization, MOF forms a discontinuous physical coating that obstructs intrinsic ion pathways, restricting rate performance of hard carbon despite the improvement in its cycling stability. In-situ EIS and distribution of relaxation time analyses disclose lower charge-transfer resistance and optimized SEI evolution in MOF@cellulose-derived carbon, facilitating efficient ion-electron dual transport. The full cell utilizing MOF@cellulose-derived carbon attains a high energy density of 172.8 Wh kg −1 at a power density of 2065 W kg −1 . This work offers mechanistic insights into the correlations among carbon microstructure, interface, and performance, guiding the rational anodes design of high-power and high-energy density sodium-ion batteries.
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高影响因子
CATALYSIS LETTERS
·
2026
·Vol. 156
·期 6
·157
·
IF 2.5
Ma Xiao,Wang Guangxing,Xu Ting,Feng Lu,Zhou Rundong,Li Cuiqin,Li Feng
Catalytic transfer hydrogenation (CTH) of furfural to furfuryl alcohol is a pivotal strategy for valorizing biomass-derived platform molecules. Herein, we report the design of a yolk-shell MOF-808@hollow mesoporous silica spheres (MOF-808@HMSS) catalyst, where MOF-808 nanocrystals are uniformly confined within the internal cavities of HMSS. Compared to pure MOF-808, the spatial confinement effect imposed by HMSS induces the formation of smaller MOF-808 nanocrystals, increasing the density of accessible active sites. The mechanically robust HMSS shell significantly enhances the structural integrity of the catalyst by mitigating mechanical attrition and suppressing leaching of active components during reaction. Notably, the unique yolk-shell architecture creates a confined nanoscale microenvironment that promotes efficient adsorption and activation of reactants at catalytic centers. Consequently, MOF-808@HMSS exhibits markedly superior performance in CTH of furfural as well as higher reusability and cycling stability compared to pure MOF-808. Detailed characterization reveals abundant Lewis acid sites with a minor proportion of basic sites in MOF-808@HMSS. Selective poisoning experiments confirm that Lewis acid sites play a predominant role in the Meerwein-Ponndorf-Verley reaction, while synergistic interplay between acidic and basic sites enhances reactant adsorption and facilitates i -propanol deprotonation, collectively accelerating the overall CTH process. Graphical The alternative text for this image may have been generated using AI.
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CHEMICAL ENGINEERING JOURNAL
·
2026
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IF 12.5
Hui Su,Jian Yin,Jialu Wei,Hao Yang,Pengde Han,Zhangping Wang,He Lin,Lei Xie,Xiao Huang,Jinping Lan,Yong Huang
The GD/MOF@3DE composite enabled pH-responsive release of Zn 2+ , Co 2+ , and 3DExos. • Zn 2+ and Co 2+ provided antibacterial/anti-inflammatory and antioxidant/pro-angiogenic effects, respectively. • Released 3DExos promoted M2 macrophage polarization and directly stimulated osteogenesis. • Transcriptomics revealed enhanced osteogenesis via ECM/HIF-1 pathway regulation. • The multifunctional coating promoted infected bone repair and implant integration in vivo . The compromised bone-implant interface microenvironment, regulated by oxidative stress, infection, inflammation, and disrupted bone homeostasis, remains the core challenge for effective titanium-bone integration. To address these issues, a composite hydrogel coating was fabricated on the titanium substrate, which consisted of a dual-network hydrogel based on a bimetallic metal-organic framework (Zn/Co-MOF) and incorporated gelatin methacryloyl-dialdehyde starch (GelMA-DAS, GD) co-loaded with human umbilical cord mesenchymal stem cell-derived three-dimensional exosomes (hUCMSC-3DExos, 3DE). The resulting GD/MOF@3DE coating exhibited infection-responsive (low-pH) behavior, enabling on-demand release of Zn, Co, and 3DExos. In vitro , the coated titanium effectively scavenged excess intracellular ROS and improved mitochondrial function. It also demonstrated potent anti-inflammatory activity by promoting macrophage polarization toward the M2 phenotype. The modified substrate showed excellent biocompatibility, broad-spectrum antibacterial efficacy against Gram-positive and Gram-negative pathogens, and significant upregulation of osteogenic markers. Transcriptomic analysis revealed that osteogenesis was promoted through regulation of key pathways, including extracellular matrix organization and HIF-1 signaling. Moreover, the coating displayed pronounced angiogenic and immunomodulatory osteogenic potential. Subcutaneous infection models and femoral defect repair experiments confirmed that this multifunctional coating possesses outstanding anti-infective, antioxidative, anti-inflammatory, angiogenic, and osseointegrative properties, offering an innovative strategy for modulating the postoperative microenvironment around orthopedic implants.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
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IF 8.3
Li Wang,Kang Wei,Congtian Yu,Zhengwu Wang,Lurong Xu,Yang Wei,Xinlin Wei
In response to the urgent public demand for food safety and ecological protection, the sensitive detection and efficient removal of glyphosate (GPS) are of paramount importance. Herein, a multifunctional aerogel (Ru@ZrMOFs@AG) based on agarose (AG) and multi-emissive metal organic frameworks was rationally designed to simultaneously achieve colorimetric-fluorescence dual-mode detection and high-efficiency removal of GPS. The fabricated Ru@ZrMOFs@AG aerogel exhibited exceptional adsorption performance towards GPS pesticides, with a maximum adsorption capacity reaching 133.87 mg/g, and maintained good reusability following five consecutive adsorption/desorption cycles. Particularly, this composite material is endowed with dual-emission fluorescent characteristics (with emission peaks at 450 nm and 600 nm), while simultaneously exhibiting remarkable peroxidase-like activity. In the presence of hydrogen peroxide, it efficiently catalyzes the oxidation of colorless o-phenylenediamine into yellow 2,3-diaminophenazine. Notably, upon introduction of GPS into the system, the fluorescence intensity of Ru@ZrMOFs@AG at 450 nm significantly increased, whereas the emission at 600 nm remained stable; concurrently, GPS markedly inhibited its peroxidase-mimicking activity, leading to a decrease in the system’s absorbance. This dual-mode sensor enabled ultra-trace quantification of GPS, with detection limits of 0.98 ng/mL and 2.11 ng/mL for the ratiometric fluorescence and colorimetric modalities, respectively. Therefore, the developed Ru@ZrMOFs@AG aerogels combine stable fluorometric and colorimetric performance, exceptional adsorption capacity, and facile recyclability, offering an economically efficient and environmentally friendly solution for the simultaneous removal and monitoring of GPS.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Xue Tian,Shanping Wang,Wen-Wen Dong,Jiahao Li,Yu Liu,Jun Zhao,Dong-Sheng Li
The in situ synthesis method is developed to chemically integrate dye@MOF systems with BNNS. • The SRh101@ZIF-BN composite retains excellent photoluminescent properties with a marked stability. • The resulting WLED exhibits superior performance and a notable 12.3 °C reduction in operating temperature. Dye@MOF composites show great potential for solid-state lighting, yet their practical deployment is hindered by insufficient stability. To address this challenge, we develop a red-emitting composite, SRh101@ZIF-BN, by in situ anchoring dye-incorporated MOFs onto ultrathin boron nitride nanosheets (BNNS).Systematic investigation of their microstructure, photoluminescence (PL) characteristics, and stability under various environmental conditions (ambient air, blue light irradiation, and elevated temperatures) confirms that the chemical integration of BNNS not only preserves the outstanding PL properties, but also significantly enhances photothermal stability, markedly outperforming physically blended BN additives. Finally, a high-performance white light-emitting diode (WLED) is fabricated by integrating the optimized SRh101@ZIF-BN composite with YAG:Ce 3+ phosphor on a 450 nm blue LED chip. The resulting device achieves excellent performance metrics: CIE color coordinates of (0.33, 0.33), a correlated color temperature (CCT) of 5096 K, an impressive color rendering index (CRI) of 91.1, and a luminous efficacy (LE) of 103.18 lm/W. Moreover, the operating temperature of the WLED is reduced by 12.3 °C compared to that based on the pristine SRh101@ZIF-8 phosphor. This work establishes an effective BNNS-stabilization strategy and opens a promising pathway for durable and efficient dye@MOF materials in advanced lighting applications. Download: Download high-res image (180KB) Download: Download full-size image
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MICROCHEMICAL JOURNAL
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2026
·
IF 5.2
Jiaze Tang,Cuiping Li,Ruonan Li,Beining Zhang,Shujuan Ren,Jie Chen,Haibo Weng,Zhaowei Sun
Accurately distinguishing structurally analogous phosphate species represents a persistent analytical challenge in biomedical and environmental analysis. To address this, we developed a novel fluorescent sensor array for the effective multiplexed identification of phosphates based on a library of metal-organic frameworks (MOFs). Three MOFs were synthesized from the ligand 2,5-dihydroxyterephthalic acid (DHTP) and Zn 2+ , Co 2+ , and Cu 2+ . The fluorescence of these MOFs, initially quenched via photoinduced electron transfer (PET), is specifically restored upon phosphate exposure via a dual-response mechanism involving the surface esterification with hydroxyl groups and competitive coordination to metal nodes, leading to framework disassembly. Differential binding affinities between phosphates and the three metal centers generate unique fingerprint-like response patterns across the three-channel array. By integrating with linear discriminant analysis (LDA), we achieved rapid and accurate discrimination of multiple phosphate species, including nucleotides (AMP, ADP, ATP, H 4 P 2 O 7 ) and inorganic phosphates with 100% classification accuracy. Moreover, quantitative analysis results showed that the method has a broad linear range of 0.5–8 μM with a low limit of detection (LOD) of 0.051 μM for H 4 P 2 O 7 , 0.342 μM for ATP and 0.105 μM for NaH 2 PO 4 . This label-free, washing-free sensing protocol demonstrates high sensitivity, excellent reproducibility, and reliable performance in complex matrices, offering a robust and versatile platform for applications requiring precise phosphate differentiation, such as clinical diagnostics and environmental monitoring.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2026
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IF 4.8
Yang Zhou,Xin Gu,Hongmin Gao,Hehua Zhang,Ying Liu,Dong Chang,Hongzhi Pan
The abnormally high expression of MUC1 in various malignant tumors makes it a crucial biomarker for early cancer diagnosis. This study synthesized a Cu-MOF@PtPdNPs nanocomposite exhibiting robust peroxidase-like activity via an in-situ reduction method. By integrating this nanomaterial with a dual-aptamer recognition sandwich strategy, an efficient colorimetric sensor was constructed for MUC1 detection. The nanozyme modified with aptamer2 (Cu-MOF@PtPdNPs-Apt2) was used to specifically recognize the target MUC1. Then, magnetic beads modified with aptamer1 (MB-Apt1) were used to enrich and separate the Cu-MOF@PtPdNPs-Apt2@MUC1, forming sandwich complexes. The sandwich complexes were separated and removed using magnets, and the remaining Cu-MOF@PtPdNPs-Apt2 in the supernatant was used for colorimetric detection. This sensor exhibits a linear range from 1 ng/mL to 100 μg/mL, alongside a limit of detection (LOD) of 0.211 ng/mL. Benefiting from the ingenious sandwich architecture, the sensor demonstrates high selectivity toward MUC1 and shows a good response in human serum, with recovery rates between 92.00% and 97.82%. In conclusion, this study provides a fast and sensitive technical platform for MUC1 detection.
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PubMed
高影响因子
NANO
·
2025
·
IF 1.1
Peixuan Zou,Yusong Pan,Kuen-Song Lin,Wei-Chin Tsai,Yinghai Xie,Wenjie Luo,Run Huang,Xiuling Lin
The use of nanocarriers with combined photothermal and chemotherapeutic methods has been widely accepted as a promising anti-tumor treatment strategy. Leveraging the tumor-specific microenvironment, these nanocarriers enhance therapeutic outcomes. Our research developed an innovative drug carrier platform, which was composed of the Metal-Organic Framework (MOF) HKUST-1 as a drug carrier and the Fe 3 O 4 nanoparticles as a photothermal functional phase. This novel carrier demonstrated an impressive drug loading rate of 110% for Doxorubicin (DOX), suggesting a high capacity for drug delivery. Additionally, the as-prepared nanocarrier also displayed excellent photothermal conversion capability, which can efficiently convert light into heat under near-infrared light with 980 nm irradiation, thus utilizing photothermal therapy for tumors. The release mechanism of pH sensitivity of the carrier expedited drug release under acidic conditions, aligning with the tumor microenvironment. Biocompatibility assays confirmed the excellent compatibility of Fe 3 O 4 @HKUST-1 with normal tissue cells. While photothermal therapy alone successfully induced apoptosis in tumor cells, the treatment’s efficacy requires improvement as cell viability remained at 80%. Conversely, combining chemotherapy with photothermal therapy decreased cell viability to 30%, thereby effectively inhibiting proliferation. In sum, the Fe 3 O 4 @HKUST-1 drug delivery system exhibits significant potential in medical applications due to its dual-therapy approach.
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高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2026
·
IF 4.1
Gao Haonan,Wen Mingzhen,Li Jiali,Hou Shili,Li Lifen,Liu Guangyan
This work develops an in situ electrodeposition strategy to construct a honeycomb-like Ni/Co-MOF/MXene heterojunction directly on the glassy carbon electrode (GCE) surface at −1.3 V vs. Ag/AgCl, enabling ultrasensitive enzymatic electrochemical detection of trace urea. The high catalytic activity of Ni/Co-MOF and the superior conductivity of MXene were synergistically integrated in a 3D hierarchical heterostructure. Compared with traditional modification methods, this strategy significantly enhances the kinetics of electron transfer and the stability of urease immobilization. Characterized by scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS), the heterojunction exhibits unique morphology and outstanding electroconductivity. Furthermore, the resulting Ni/Co-MOF/MXene/urease/GCE biosensor achieves a wide linear range of 1.0 × 10 –6 –1.0 × 10 –4 mol L −1 with a low detection limit of 4.9 × 10 –7 mol L −1 . The biosensor has been applied to the detection of practical samples, where the recoveries were 99.3–102.8% with a relative standard deviation (RSD) of 2.9–3.3%, which indicates that this biosensor has good practical applications and prospects for further development.
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产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2026
·
IF 19.7
Xin Yu,Xinqi Luan,Xuehui Jia,Ruimeng Wang,Yaofei Ren,Yang Hu,Jiahua He,Zhongxing Zhao,Zhenxia Zhao
Designing the photocatalyst that possesses both efficient diluted carbon dioxide (CO 2 ) enrichment and photocatalytic conversion capabilities is a key challenge for the direct utilization of low-concentration CO 2 (15%) from flue gas. Herein, we proposed an interlayer ligand insertion strategy to construct a high-density integrated adsorption-catalysis system between NH 2 -UiO-66(Zr) (U66N) and functionalized TPB-DMTP-COF with benzoic acid groups (COF-T) for highly efficient photocatalytic diluted CO 2 reduction. In the photocatalytic CO 2 reduction reaction, the diluted CO 2 was first adsorbed and enriched to the microporous structure constructed between COF-T and U66N. Simultaneously, the two-dimensional COF-T acts as the primary light-harvesting component, preferentially capturing photogenerated electrons and holes under visible light and directing their transport to the catalytic interface of the three-dimensional U66N through steric-hindrance-induced distorted coordination linkages. Then the CO 2 molecules progressively activated by using the delivered electrons and H + , ultimately converting into CO. This ordered high-density integration architecture of COF and MOF concurrently optimizes light absorption and charge transfer pathways, enables precise regulation of the catalytic centers, and thereby substantially lowers the energy barrier for the formation of the *COOH intermediate in the photocatalytic CO 2 reduction, resulting in enhanced overall catalytic performance. Consequently, COF-T/U66N achieves a remarkable CO production rate of 65.0 µmol·g -1 ·h -1 under diluted CO 2 (15%), with near-unity (∼100%) selectivity and without adding any photosensitizer and sacrificial agent, surpassing state-of-the-art inorganic or porous photocatalysts by 5–40 times. This work not only provides a feasible strategy for the efficient photocatalytic reduction of low-concentration CO 2 but also offers a universal method for the design of MOF/COF composite materials.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2026
·Vol. 37
·期 1
·42
·
IF 4.7
Xiaomei Ye,Shuzhen Lu,Hao Peng,Zhirong Huang,Chunyu Pan,Yayan Huang,Kangrui Yuan,Youfa Qin
Mesoporous metal-organic frameworks (MOFs) have the advantages of high specific surface area, tunable pore size, and favorable biocompatibility, making them promising candidates for drug delivery in cancer therapy. In this study, a series of mesoporous zinc-based MOF, constructed using cyclopentane dicarboxylic acid as the organic linker, was successfully synthesized via a surfactant-assisted solvothermal method. Surface characterization revealed that MOF-2 exhibited high surface area (1325 m 2 /g), pore volume (0.273 cm 3 /g), and average pore diameter (5.69 nm). UV-Vis analysis showed that MOF-2 demonstrated improved drug loading (18% w/w), encapsulation efficiency (86%), and cumulative release (96%), along with both pH-responsive degradation and drug release properties. Furthermore, cisplatin-loaded MOF-2 exhibited potent antitumor activity against A549 cells and effectively inhibited cell migration and invasion, while maintaining minimal cytotoxicity toward LO2 normal hepatic cells. These findings suggest MOF-2 as a promising nanocarrier for pH-responsive anticancer drug delivery.
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PubMed
高影响因子
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