SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Zi-Hang Zhang,Xiao-Bo Zhang,Pu Wang,Su-Hang Xu,Zuo-Qin Liang,Chang-Qing Ye,Xiao-Mei Wang
Iron ion (Fe 3+ ) detection is crucial for human health since it plays a crucial role in many physiological activities. In this work, a novel Schiff-base functionalized cyanine derivative (CyPy) was synthesized, which was successfully assembled on the surface of upconversion nanoparticles (UCNPs) through an amphiphilic polymer encapsulation method. In the as-designed nanoprobe, CyPy, a recognizer of Fe 3+ , is served as energy donor and β-NaYF 4 :Yb,Er upconversion nanoparticles are adopted as energy acceptor. As a result, a 93-fold enhancement of upconversion luminescence is achieved. The efficient energy transfer from CyPy to β-NaYF 4 :Yb,Er endows the nanoprobe a high sensitivity for Fe 3+ in water with a low detection limit of 0.21 μM. Moreover, the nanoprobe has been successfully applied for Fe 3+ determination in human serum and tap water samples with recovery ranges of 95 %-105 % and 97 %-106 %, respectively. Moreover, their relative standard deviations are all below 3.72 %. This work provides a sensitive and efficient methodology for Fe 3+ detection in clinical and environmental testing.
研究领域:
分析化学
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材料科学
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环境科学
·
生物医学工程
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DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2025
·
IF 5.1
Tingjie Jiang,Na Yang,Ziyi Wang,Haoran Zhang,Na Li,Yongying Chen,Mingkai Wei,Xuejie Zhang,Bingfu Lei
In this study, a carbon dot-based ratiometric fluorescence (RF) probe was used as a fluorescent "on-off-on" sensor to detect Fe3+ and the pesticide amitrole (AMT). The RF probe consists of orange carbon dots (O-CDs) and blue carbon dots (B-CDs). B-CDs forms a ground-state complex with Fe3+ which leads to fluorescence quenching, while the addition of AMT restores fluorescence. Based on this "on-off-on" process, a quantitative detection of Fe3+ and AMT is achieved, showing good linearity in the range 0-50 μM and 0-30 μM. The low detection limit of Fe3+ and AMT are as low as 24 nM and 0.18 μM, respectively. In addition, fluorescent color changes are converted into RGB values by a smartphone sensing device., and the concentration of Fe3+ and AMT is determined by colorimetric analysis. The method was further applied to real samples such as lake water, tap water and urine with satisfactory results. Additionally, a portable sensor with a semi-hydrophobic film was fabricated for on-site AMT detection, showcasing practical applicability. This work provides a cost-effective, rapid, and dual-mode strategy for environmental and biological monitoring of Fe³⁺ and AMT.
研究领域:
环境监测
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分析化学
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纳米技术
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生物传感
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荧光光谱学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2024
·Vol. 25
·期 23
·12518
·
IF 4.9
Mingyu Jia,Jueyu Wang,Yuxuan Liu,Daizong Cui,Min Zhao
In this study, Fe3(PO4)2·8H2O magnetic nanoparticles (MNPs) were successfully extracted from the strainBurkholderia cepaciaCG-1. We subsequently characterized their composition, structure, and morphology, revealing that these nanoparticles consisted of Fe3(PO4)2·8H2O with an average diameter of 66.87 ± 0.56 nm. Our measurements indicated magnetic parameters of 151 Oe for coercivity, 2 emu/g for saturation remanence, and 16 emu/g for saturation magnetization. Our findings confirmed that these magnetic nanoparticles exhibited intrinsic peroxidase-like activity, catalyzing the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of H2O2. Compared to horseradish peroxidase (HRP), the peroxidase mimic demonstrated greater stability under various physicochemical conditions. To investigate the mechanisms underlying the peroxidase-like catalysis of Fe3(PO4)2·8H2O, we employed fluorescence spectroscopy and electron spin resonance (ESR) analysis. The results revealed that the peroxidase-like activity of Fe3(PO4)2·8H2O stemmed from the generation of hydroxyl radicals (·OH). Furthermore, we established a platform for the colorimetric detection of H2O2and glucose. Our method was capable of detecting H2O2concentrations as low as 1.0 × 10−3mmol/L. Impressively, this sensitive method was successfully applied to determine glucose levels in human serum.
研究领域:
生物化学
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纳米医学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2015
·
IF 4.513
Wenjing Lu,Xiaojuan Gong,Ming Nan,Yang Liu,Shaomin Shuang,Chuan Dong
A facile and eco-friendly approach to prepare nitrogen(N)- and sulfur(S)-doped carbon dots (CDs) by one step microwave-assisted pyrolysis of the precursors with dl -malic acid as carbon source, ethanolamine and ethane-sulfonic acid as N and S dopants, respectively, was reported. Through the extensive investigation on morphology, chemical structures and optical properties of the carbon dots, it was found that the obtained CDs exhibited good luminescence stability, high resistance to photo bleaching and favorite solubility. Compared with undoped CDs, adding the N or S dopant could give rise to a slightly smaller particle size and a long fluorescence lifetime of CDs. Moreover, the optimal N-CDs was successfully employed as good multicolor cell imaging probes due to its fine dispersion in water, excitation-dependent emission, excellent biocompatibility and low toxicity. Besides, such N-CDs showed a wide detection range and excellent accuracy as fluorescent probe for Fe 3+ ions. This probe enabled the selective detection of Fe 3+ ions with a linear range of 6.0–200 μM and a limit of detection of 0.80 μM.
研究领域:
材料科学
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化学
·
分析化学
·
生物材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Acta Biomaterialia
·
2024
·
IF 9.4
Yue Wang,Ziyi Pan,Jing Cui,Xu Zhang,Daowei Li,Hongchen Sun,Bai Yang,Yunfeng Li
ABSTRACT Oral ulcers can significantly reduce the life quality of patients and even lead to malignant transformations. Local treatments using topical agents are often ineffective because of the wet and dynamic environment of the oral cavity. Current clinical treatments for oral ulcers, such as corticosteroids, have limitations and side effects for long-term usage. Here, we develop adhesive hydrogel patches (AHPs) that effectively promote the healing of oral ulcers in a rat model. The AHPs are comprised of the quaternary ammonium salt of chitosan, aldehyde-functionalized hyaluronic acid, and a tridentate complex of protocatechualdehyde and Fe 3+ (PF). The AHPs exhibit tunable mechanical properties, self-healing ability, and wet adhesion on the oral mucosa. Through controlling the formula of the AHPs, PF released from the AHPs in a temporal manner. We further show that the AHPs have good biocompatibility and the capability to heal oral ulcers rapidly. Both in vitro and in vivo experiments indicate that the PF released from AHPs facilitated ulcer healing by suppressing inflammation, promoting macrophage polarization, enhancing cell proliferation, and inducing epithelial-mesenchymal transition involving inflammation, proliferation, and maturation stages. This study provides insights into the healing of oral ulcers and presents an effective therapeutic biomaterial for the treatment of oral ulcers. Statement of significance By addressing the challenges associated with current clinical treatments for oral ulcers, the development of adhesive hydrogel patches (AHPs) presents an effective approach. These AHPs possess unique properties, such as tunable mechanical characteristics, self-healing ability, and strong adhesion to the mucosa. Through controlled release of protocatechualdehyde-Fe 3+ complex, the AHPs facilitate the healing process by suppressing inflammation, promoting cell proliferation, and inducing epithelial-mesenchymal transition. The study not only provides valuable insights into the healing mechanisms of oral ulcers but also introduces a promising therapeutic biomaterial. This work holds significant scientific interest and demonstrates the potential to greatly improve the treatment outcomes and quality of life for individuals suffering from oral ulcers.
研究领域:
生物医学工程
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药学
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组织工程
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伤口愈合
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2019
·
IF 2.931
Kui Chen,Weixia Qing,Weiping Hu,Minghua Lu,Yong Wang,Xiuhua Liu
In this work, we reported an economical plant-based hydrothermal method for one-pot green synthesis of water-soluble carbon dots (Tea-CDs) by using waste tea extract as a carbon source. The synthesized Tea-CDs were characterized by UV–visible, fluorescence, FT-IR, TEM, XPS and XRD. The Tea-CDs were found to remove hydroxyl and superoxide anion radical in vitro. In addition, the Tea-CDs exhibited bright blue fluorescence under UV-light (λ ex = 365 nm), and the fluorescence could be effectively quenched by CrO 4 2− and Fe 3+ ions. Meanwhile, the fluorescence of Tea-CDs-CrO 4 2− and Tea-CDs-Fe 3+ systems could be again easily recovered by ascorbic acid (AA) and L-cysteine (L-Cys). As an on-off-on fluorescent nano-sensor of the Tea-CDs, the sensitive detection of CrO 4 2− , Fe 3+ , AA and L-Cys were all performed, showing that the good linear relationships between fluorescence intensity of Tea-CDs and concentration of all testing samples. Finally, the sensors successfully detected CrO 4 2− , Fe 3+ , AA and L-Cys in commercially available real samples with satisfactory recovery ranges. The prepared sensors offer distinct advantages including low cost, simple handling, good sensitivity and high selectivity.
研究领域:
材料科学
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环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2024
·
IF 3.2
Rui Cao,Xinxin Li,Teng Zhang,Hanxiao Tang,Ying Song,Zhijuan Zhang,Weisheng Feng
The development of metal ion detection probes with high sensitivity and selectivity is of utmost importance for the promotion of public health and environmental sustainability. In this work, a series of ratiometric fluorescent probes (RhB@UiO-67-NH 2 ) were successfully prepared using a one-pot method for the detection of metal ions, particularly As 5+ and Fe 3+ . Notably, the ratiometric fluorescent probe RhB@UiO-67-NH 2 (1:4) demonstrates dual functionality as a Fe 3+ turn-off probe and an As 5+ turn-on probe. The limits of detection (LODs) for As 5+ and Fe 3+ using RhB@UiO-67-NH 2 (1:4) were determined to be 0.521 μM (39.03 ppb) and 0.107 μM (5.97 ppb), respectively, which were the lowest records of reported LMOFs so far. The fluorescence quenching of Fe 3+ can be attributed to various mechanisms such as fluorescence resonance energy transfer (FRET), photoinduced electron transfer (PET), and competitive absorption (CA). Additionally, the fluorescence enhancement of As 5+ is primarily due to absorbance-caused enhancement (ACE) and PET. Moreover, the composite material RhB@UiO-67-NH 2 (1:4) exhibited excellent anti-interference capability and reproducibility for detecting Fe 3+ and As 5+ . The removal efficiency of As 5+ by RhB@UiO-67-NH 2 (1:4) exceeded 50.9 % when the initial concentration of As 5+ was below 20 mg/L. This work presents a valuable reference for future investigations and utilization of As 5+ and Fe 3+ sensing.
研究领域:
分析化学
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环境科学
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材料科学
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产品关联
DOI
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2019
·Vol. 35
·期 2
·200-208
·
IF 1.071
Shi Yanpeng,Chen Xiaodong,Mi Zhiming,Zheng Ran,Fan Jie,Gu Qiang,Zhang Yumin
Two new compounds, 4-(2-bromophenyl-4,5-diphenyl-imidazol-1-yl)aniline(probe 1 ) and 4-[2,4,5-tris(4-bromophenyl)-1 H -imidazol-1-yl]aniline(probe 2 ), were synthesized via a soft and high-efficiency one-pot microwave- assisted method under solvent-free conditions. Their sensing to different metal ions was detected by UV spectrophotometry and fluorescence spectrometry. Probe 2 revealed highly selective and sensitive UV and fluorescence response to Fe 3+ ion. Upon the addition of Fe 3+ ion, probe 2 showed obvious color change of the solution, conspicuous absorbance enhancement and relatively quick fluorescence quenching. The detection limit for Fe 3+ ion was respectively calculated to be 0.72 μmol/L(fluorescent detection) and 0.48 μmol/L(UV-spectrum detection). Also, probe 2 was bound by Fe 3+ ion to form a 1:1 complex. Moreover, preliminary application of probe 2 for detecting Fe 3+ ion in aqueous solution was attempted, and satisfying results were obtained.
研究领域:
分析化学
·
无机化学
·
材料科学
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Bing Zhang,Hongyun Meng,Xue Wang,Jing Li,Honghong Chang,Wenlong Wei
Herein we designed a novel photoelectrochemical sensing platform based on Fe 3+ doped ZnO-Ag photocatalyst (Fe 3+ /ZnO-Ag) for ultrasensitive Hg 2+ detection by using exonuclease III-assisted target recycling and DNAzyme-catalyzed amplification. Firstly, Fe 3+ /ZnO-Ag was synthesized to provide photocurrent under visible light irradiation. Secondly, target Hg 2+ was determined by hairpin DNA probes on the Fe 3+ /ZnO-Ag modified ITO based on T-Hg 2+ -T, and then Hg 2+ was released by the digestion of exonuclease III to double-stranded DNA. Finally, the photocurrent markedly decreased due to catalysis of hemin/G-quadruplex toward 4-chloro-1-naphthol. Under optimal conditions, the photocurrents were linearly related to Hg 2+ concentrations form 0. 5 nM to 100 nM with a detection limit of 0. 1 nM at the 3 S blank criterion. More importantly, the developed biosensor exhibited good selectivity, repeatability, and stability, meanwhile, this analysis platform held great potential for testing real water samples in future.
研究领域:
环境科学
·
分析化学
·
纳米技术
✓ 已验证
DOI
高影响因子
NANO
·
2017
·
IF 1.025
Yin Zhong,Qi Chen,Junjian Li,Xihao Pan,Zhiwei Han,Wei Dong
An environment friendly, economic and maneuverable hydrothermal method was proposed for fabrication of nitrogen and chlorine co-doped carbon quantum dots (N,Cl-CQDs). D-Glucosamine hydrochloride as the only precursor offered source of carbon, nitrogen and chlorine. As a consequent N,Cl-CQDs can emit blue luminescence and detect Fe 3 + by fluorescence response with high selectivity and sensitivity. There is a linear semilogarithmic correlation between the quenching efficiency F 0 ∕ F and the concentration of Fe 3 + with a detection limit of 0.167 μ M. The N,Cl-CQDs exhibit a high quantum yield of 16.8% along with the fluorescence lifetime of 2.2 ns. It is worth noting that the prepared N,Cl-CQDs show excellent biocompatibility and they are promising materials for sensing and biology.
研究领域:
材料科学
·
分析化学
·
纳米技术
·
环境科学
·
生物技术
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2018
·
IF 2.746
Yuanlin Huang,Tianran Lin,Li Hou,Fanggui Ye,Shulin Zhao
Based on Fenton reaction without adding nanomaterials , a simple colorimetric sensor for detecting thioglycolic acid (TGA) was developed. By reducing Fe 3+ ions to Fe 2+ ions, TGA efficiently stimulates Fenton reaction through accelerating Fe 3+ /Fe 2+ redox cycle. Owing to this, the accelerated decomposition of H 2 O 2 generates more OH radicals, which cause a significant blue change in the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB). Compared with Fe 3+ /H 2 O 2 /TMB system, this sensor can be operated over a wider pH range from 4.0 to 8.0. The calibration curve of TGA is achieved in the concentration range of 0.046–7.37 μg mL −1 under optimized conditions, and the detection limit of TGA is 0.036 μg mL −1 (S/N = 3). This sensor has been successfully applied to the detection of TGA in cold wave lotion with recovery rates between 99.1 and 101.6%, which has broad application prospects in cosmetic analysis and environmental monitoring.
研究领域:
分析化学
·
环境科学
·
化妆品科学
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2015
·
IF 4.097
Lina Xu,Wei Mao,Jinrui Huang,Shouhai Li,Kun Huang,Mei Li,Jianling Xia,Qiang Chen
A facile, economical, and green method has been developed to prepare a new fluorescent sensor based on ligninsulfonate/graphene quantum dots (SL/GQDs) core/shell hybrids for label-free sensitive and selective detection of Fe 3+ . The combination of these two materials brings both excellent photoluminescent properties (the fluorescence intensity of SL/GQDs composites is four times higher than the free GQDs) and nice selectivity. In this composite, SL molecule plays two key roles in the system as a π-rich and sulfur-incorporated compound to enhance the fluorescence and as a chelator to detect Fe 3+ . The obtained sensor presents excellent sensitivity and selectivity toward Fe 3+ and exhibits a good linearity in the range of 0.005–500 μM with a detection limit as low as 0.5 nM. We have further explored the practical use of such proposed probe for Fe 3+ determination in lake water samples, which shows promise in environmental determination.
研究领域:
材料科学
·
环境化学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）