Nano Research
·
2021
·Vol. 14
·期 12
·4795-4801
·
IF 8.897
Hu Zheng,Yuan Tingbiao,Li Hui,Qiu Yishu,Zhou Wei,Zhang Jiangwei,Zhao Yuxin,Hu Shi
Two-dimensional (2D) oxide can be continuously produced by bubbling oxygen into liquid metals and the harvesting of these oxide relies on the proper choice of dispersion solvents. The mass-production of ligand-free 2D materials from high melting-point metals will not be possible if the limited stability of the traditional dispersion solvents is not circumvented. Herein, liquid tin was used for the first time in the bubbling protocol and 2D tin oxide was obtained in molten salts. The nanosheets were studied with combined microscopic and spectroscopic techniques, and high-density grain boundaries was identified between the sub-5-nm nano-crystallites in the nanosheets. It gives rise to the high performance in electrocatalytic CO 2 reduction reaction. Density-functional-theory based calculation was applied to achieve a deeper understanding of the relationship between the activity, selectivity, and the grain-boundary features. The molten-salt based protocol could be explored for the synthesis of a library of functional 2D oxides.
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JOURNAL OF MATERIALS SCIENCE
·
2021
·Vol. 56
·期 20
·12018-12029
·
IF 4.22
Chen Juan,Gong Caihong,Yang Ce,Yi Chunwang
The harsh synthesis conditions and lack of hard segments have long presented difficulties in the preparation of polyamide-based thermoplastic elastomers (TPAEs). In this work, a facile synthesis of TPAEs was developed using amide exchange. First, itaconic acid-polyoxypropylene diamine copolymer (IA-PPA) was synthesized by copolymerizing bio-based polyoxypropylene diamine (PPA D400) and itaconic acid (IA). The P2000 (IA-PPA with Mn ~ 2000) was then used as the soft segment of polyamide-6 based thermoplastic elastomers (PA6- b -P2000). Experimental results indicate that P2000 could directly initiate the ring-opening polymerization of caprolactam to form a prepolymer containing PA6 segments. PA6- b -P2000 thermoplastic elastomers were then obtained by the amide exchange reaction of PA6 segments. The structure and properties of IA-PPA and PA6- b -P2000 were further characterized in detail. The results demonstrate that the elastomers have good thermal stability and superior elasticity, which are highly dependent on the crystallinity and phase separation structure of the polyamide elastomer. Using this flexible approach, multifunction TPAEs can be designed and commercialized in a short time.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2021
·Vol. 37
·期 3
·549-557
·
IF 1.307
Wang Yan,Xi Peng,Shu Dengkun,Meng Shuang,Liu Kai,Wang Xiaoqing,Cheng Bowen
M ulti-functional nanofibers are playing an important role in the optical field, and are widely used in fluorescence indication, product anti-counterfeit identification and smart clothing. Nanofibers with photoluminescence and photochromic functions are already attracting more interest from researchers. In this work, based on electrospun technology, the modified-PMMA nanofibers[PMMA=poly(methyl methacrylate)] with photoluminescence and photochromic functions were prepared through the design of the sheath-core structure(SCNFs 1–4). Compared with other samples, SCNF-4 shows outstanding photoluminescence and photochromic functions. SCNF-4 can produce green light and its fluorescence intensity and fluorescence lifetime can reach 7144 a.u. and 1031.32 µs, respectively. In photochromic functions, SCNF-4 can show purple in 1 min under the 365 nm ultraviolet light, and the color can be preserved for more than 4 h under the sunlight. When SCNF-4 is irradiated by far infrared light, the color of the samples can fade quickly in 40 s. Under the irradiation of ultraviolet light of different wavelengths, SCNF-4 can display multi-color fluorescence and achieve a reversible transition between white and purple. The design of the sheath-core structure realizes the complementarity of photoluminescence and photochromic functions of the electrospun modified-PMMA nanofibers, which is important to promote the wide application of multi-functional nanofibers in the optical field.
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Biomass Conversion and Biorefinery
·
2021
·Vol. 12
·期 8
·3503-3511
·
IF 4.987
Huang Xin,Xu Anbang,Bu Xinyuan,Huang Yong,Ran Jingyu
Levoglucosenone (LGO), derived from catalytic pyrolysis of cellulose, has shown its potential as a bio-renewable platform for the production of fine and commodity chemical. In this study, we report a biphasic system for conversion of LGO to 5-hydroxymethylfurfural (HMF) and levulinic acid (LA) with a substantial yield. The hydrolysis parameters, including single-biphasic phase, catalyst, temperature, and reaction time, were investigated on LGO conversion, respectively. The results showed that NaCl/H 2 O-MIBK biphasic system led to a profoundly increase of HMF selectivity by 37% compared to aqueous phase. An increase of acid site significantly enhanced LGO conversion and meanwhile promoted overreaction of HMF to LA and humins. Thus, HMF yield was observed firstly increased and then decreased with a maximum yield of 53.6% by using oxalic acid as a catalyst. The biphasic system effectively suppressed the humins formation and resulted in a maximum total HMF and LA yield of 86.7%.
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Scientific Reports
·
2021
·Vol. 11
·期 1
·1-9
·
IF 4.38
Zhou Zhiyong,Qiu Nanqing,Ou Yuntao,Wei Qianqian,Tang Wenting,Zheng Mingcong,Xing Yaluan,Li Jie-Jia,Ling Yong,Li Junxu,Zhu Qing
Chronic pain is a significant public health problem that afflicts nearly 30% of the global population, but current pharmacotherapies are insufficient. Previous report indicated that N -demethylsinomenine, an active metabolite of sinomenine, is efficacious against postoperative pain. The present study investigated whether N -demethylsinomenine is effective for chronic painful conditions or whether repeated treatment alters its effect. Both chronic constriction injury (CCI) surgery and complete Freund’s adjuvant (CFA) intraplantar injection induced significant and reliable mechanical allodynia at least for 7 days. Acute treatment with N -demethylsinomenine (10–40 mg/kg, i.p.) dose-dependently attenuated the mechanical allodynia both in CCI-induced neuropathic pain and CFA-induced inflammatory pain in mice. The potency of N -demethylsinomenine for reducing CFA-induced mechanical allodynia was slightly higher than sinomenine. During the period of repeated treatment, N -demethylsinomenine maintained its anti-allodynic effect against both neuropathic and inflammatory pain without producing carry-over effect. Pretreatment with bicuculline, a selective γ-aminobutyric acid type A (GABA A ) receptor antagonist, almost completely blocked the anti-allodynia of N -demethylsinomenine (40 mg/kg) both in CCI and CFA-treated mice. Our findings indicated that N -demethylsinomenine exhibits GABA A receptor-mediated anti-allodynic effects in mouse models of neuropathic and inflammatory pain, suggesting it may be a useful novel pharmacotherapy for the control of chronic pain.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2021
·Vol. 28
·期 29
·39513-39523
·
IF 4.223
He Jun,Song Wenchao,Huang Xiaohan,Gao Zuoyu
Magnesium oxide/expanded graphite (MgO/EG) catalyst was synthesized and applied for enhancing the degradation of Cu-ethylenediaminetetraacetic acid (Cu-EDTA) in an aqueous solution. The MgO/EG catalyst was characterized by XRD, SEM, EDS, and FTIR. For assessing the catalytic activity of MgO/EG, essential influencing factors were investigated including catalyst dosage, O 3 dosage, initial pH, initial Cu-EDTA concentration, and coexisting ions. The results show that the catalytic material showed high catalytic oxidation capacity for the Cu-EDTA removal in the MgO/EG/O 3 system. 100% of Cu(II) and 73.2% of TOC removal efficiency could be achieved in the MgO/EG/O 3 system at the reaction times of 90 min. This efficiency was higher than that seen for other systems, including O 3 alone (Cu(II) 81.4%/TOC 60.6%), EG/O 3 (84.2%/64.1), MgO/EG (< 4%/< 4%), and EG (< 4%/< 4%). A small decrease in the Cu(II) and TOC removal rate was observed after three runs in the stability and reusability experiments of the catalyst. Assays with radical scavenging experiments confirmed that MgO/EG-mediated oxidation was dependent on a hydroxyl radical pathway. The UV–vis spectra confirmed that the absorption peak of Cu-EDTA was gradually decreased and finally disappeared.
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CHINESE JOURNAL OF POLYMER SCIENCE
·
2021
·Vol. 39
·期 7
·856-864
·
IF 3.603
Wang Jing-Hong,Chen Rui,Zhao Zi-Qing,Shen Jie,Yang He,Luo Yan,Chen Gao-Jian,Chen Hong,Brash John L.
Herein we present a new perspective showing that water-soluble liquids, when added to water, undergo transient emulsification before complete dissolution. Thus, non-amphiphilic macromolecules can self-assemble at the two-miscible-phase interface when cononsolvent effect appears. A representative case shown here is that when poly( N -isopropylacrylamide) (PNIPAm), prepared by aqueous radical polymerization, in methanol solution is added into water, the polymer chains rapidly self-assemble into hollow micro-vesicles based on the cononsolvency at water/methanol interface. This finding provides a subtle strategy to prepare hollow micro-vesicles by non-amphiphilic polymers without template participating. We proposed a new concept “interfacial cononsolvency” to describe the formation process. Due to the easy modification process, sugar-contained PNIPAm chains are synthesized by copolymerization. As an application example, it is shown that these sugar-contained PNIPAm chains can afford “sweet” micro-vesicles (containing glucose residues). And the “sweet” micro-vesicles can well mimick the protocells which are involved in the recognition of bacteria.
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CELLULOSE
·
2021
·Vol. 28
·期 7
·4211-4222
·
IF 5.044
Lin Yamei,Li Mei,Xia Jianling,Ding Haiyang,Xu Lina,Yang Xiaohua,Li Shouhai
Abstract Polyols with different number of hydroxyl groups were synthesized from ricinoleic acid and oleic acid. These plant oil derived polyols can be used as plasticizers and combined with ethyl cellulose (EC) through supramolecular system to prepare ethyl cellulose composite films. The morphology, thermal stability and mechanical properties of the prepared ethyl cellulose films were studied in detail to indicate the plasticizing efficiency of these polyols and the effect of the number of hydroxyl groups in polyols on EC composite film’s properties. With the addition of polyols, the tensile strength of EC composite films decreased, while the elongation at break increased. The elongation at break of EC composite films can be improved by 11–12 times when the polyols contain 1–3 hydroxyl groups. Thus, the plant oil derived polyols with 1–3 hydroxyl groups can be used as plasticizers for EC films. In addition, molecular dynamic simulations were performed to further probe the effects of the number of hydroxyl groups in polyols on EC composite film’s properties. Graphic abstract
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Nanoscale Research Letters
·
2021
·Vol. 16
·期 1
·1-8
·
IF 4.703
Yang Mao,Jue Nan,Chen Yuanfu,Wang Yong
Uniform migration of lithium (Li) ions between the separator and the lithium anode is critical for achieving good quality Li deposition, which is of much significance for lithium metal battery operation, especially for Li–sulfur (Li–S) batteries. Commercial separators such as polypropylene or polyethylene can be prepared by wet or dry processes, but they can indeed cause plentiful porosities, resulting in the uneven Li ion stripping/plating and finally the formation of Li dendrites. Thence, we constructed an atomic interlamellar ion channel by introducing the layered montmorillonite on the surface of the separator to guide Li ion flux and achieved stable Li deposition. The atomic interlamellar ion channel with a spacing of 1.4 nm showed strong absorption capacity for electrolytes and reserved capacity for Li ions, thus promoting rapid transfer of Li ions and resulting in even Li ion deposition at the anode. When assembled with the proposed separator, the Coulombic efficiency of Li||Cu batteries was 98.2% after 200 cycles and stable plating/stripping even after 800 h was achieved for the Li||Li symmetric batteries. Importantly, the proposed separator allows 140% specific capacity increase after 190 cycles as employing the Li–S batteries.
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AAPS PHARMSCITECH
·
2021
·Vol. 22
·期 3
·1-11
·
IF 3.246
Miao Zhiwei,Zhang Lei,Gu Mingjia,Huang Jianyi,Wang Xiaoyu,Yan Jing,Xu Yan,Wang Libing
This study sought to improve the oral bioavailability and enhance the anti-enteritis effect of fraxetin by incorporating it into long circulating liposomes (F-LC-Lipo). The optimal formulation of F-LC-Lipo was obtained via orthogonal design. The particle size, morphology, encapsulation efficiency, stability, and anti-enteritis effect of F-LC-Lipo were evaluated. The particle size of F-LC-Lipo was 166.65 ± 8.75 nm with entrapment efficiency (EE) of 92.18 ± 0.17%. The release rate in different dissolution media (pH 1.2 HCl, DDW, and pH 7.4 PBS) was significantly higher than that of fraxetin solution. Compared with the free fraxetin solution, F-LC-Lipo increased oral bioavailability of fraxetin by 4.43 times (443%). More importantly, F-LC-Lipo could improve the levels of interleukin-1 beta (IL-1β), IL-6, malondialdehyde (MDA), superoxide dismutase (SOD), tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP), prostaglandin E2 (PEG2), and IL-10 in rats with enteritis. Overall, these results suggested that LC-Lipo may serve as a potential carrier for improving the solubility and oral bioavailability of fraxetin as well as improving its enteritis effect.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2021
·Vol. 28
·期 28
·37781-37792
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IF 4.223
Wang Dan,Lou Jiangfei,Xu Jin,Yuan Jiugang,Wang Qiang,Wang Ping,Fan Xuerong
Alkylphenol polyethoxylates (APEO n ) are the second-largest category of commercial nonionic surfactants, which are difficult to degrade naturally in the environment. This study examined the degradation of octylphenol polyethoxylate (OPEO n ) by laccase and its laccase-mediated systems. The results showed that OPEO n was poorly degraded by laccase alone. 2, 2′-azino-bis [3-ethylbenzothiazoline-6-sulphonic acid] (ABTS), 1-hydroxybenzotriazole (HBT), and 2, 2, 6, 6-tetramethylpiperidine-1-oxyl (TEMPO) were selected as the redox mediators. Experimental results also indicated that 52.4% of the initial OPEO n amount was degraded by laccase in the presence of TEMPO. The degradation efficiency was analyzed using high-performance liquid chromatography. Furthermore, the structural characteristics of the degradation products were measured using matrix-assisted laser desorption/ionization-time of flight mass spectrometry and nuclear magnetic resonance spectroscopy, and it could be found that the laccase-TEMPO system could gradually shorten the ethoxylate chain by oxidizing the primary hydroxyl group of OPEO n , thereby degrading the OPEO n of the macromolecule into small molecules. The maximum of the ion peak distributions of OPEO n decreased from n = 8 finally down to 3. The novel enzymatic system introduced by this study will become a promising alternative method for high-efficiency APEO n conversion and had great potential value in wastewater treatment. Graphical abstract
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AAPS PHARMSCITECH
·
2021
·Vol. 22
·期 3
·1-12
·
IF 3.246
Zhang Xueting,Chen Zhenzhen,Tao Chun,Zhang Jing,Zhang Minxin,Zhang Jialiang,Liu Zhihong,Lin Jiao,Xu Hang,Zhang Qian,Song Hongtao
The combination of self-microemulsifying drug delivery system (SMEDDS) and mesoporous silica materials favors the oral delivery of poorly water-soluble drugs (PWSD). However, the influence of the surface property of the mesopores towards the drug release and in vivo pharmacokinetics is still unknown. In this study, SBA-15 with hydroxyl groups (SBA-15-H), methyl groups (SBA-15-M), amino groups (SBA-15-A), or carboxyl groups (SBA-15-C) was combined with SMEDDS containing sirolimus (SRL). The diffusion and self-emulsifying of SMEDDS greatly improved the drug release over the raw SRL and SRL-SBA-15-R (R referred to as the functional groups). Results of drug absorption and X-ray photoelectron spectroscopy (XPS) showed strong hydrogen binding between SRL and the amino groups of SBA-15-A, which hindered the drug release and oral bioavailability of SRL-SMEDDS-SBA-15-A. The favorable release of SRL-SMEDDS-SBA-15-C (91.31 ± 0.57%) and SRL-SMEDDS-SBA-15-M (91.76 ± 3.72%) contributed to enhancing the maximum blood concentration (C max ) and the area under the concentration-time curve (AUC 0→48 ). In conclusion, the release of SRL-SMEDDS-SBA-15-R was determined by the surface affinity of the SBA-15-R and the interaction between the SRL molecules and the surface of SBA-15-R. This study suggested that the SMEDDS-SBA-15 was a favorable carrier for PWSD, and the surface property of the mesopores should be considered for the optimization of the SMEDDS-SBA-15. Graphical abstract
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危险品化学品经营许可证（带存储）