CELLULOSE
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2026
·
IF 4.6
Guo Yuqian,Cheng Yun,Zhao Yumeng,Qian Xinyu,Hou Leilei,Chen Linghua,Yang Shuo,Zhang Hongjie
The method of N-methyl-morpholine-N-oxide (NMMO) as a green and efficient solvent for dissolving fibers to prepare lyocell fibers is well known. Although we all know that the chemical composition, morphology, and pore structure of fibers determine the dissolution time of NMMO solution, it is difficult to evaluate the greatest impact factor on dissolution efficiency among the comprehensive factors. Herein, the relationship among the pore structure (specific surface area), swelling performance (maximum NMMO-retention value), and dissolution performance (dissolution time) of cellulose fibers in aqueous NMMO solution was quantitatively investigated. The novelty of this work is the quantitative evaluation of the impact of a single influencing factor (porous characteristics) on the swelling and dissolution properties. The porous characteristics of cellulose were effectively regulated without changing significant chemical structure using freeze-drying and hot-dried at 80 ℃ and 105 ℃ methods. Compared to hot-dried treatment, the freeze-dried cellulose fibers exhibited the high specific surface area (11.12 m 2 /g), highest NMMO-retention value (612%), the shortest dissolution time (40 min), which was shortened by 20 min. Higher specific surface area corresponded to the higher swell extent and dissolution efficiency by facilitating the diffusion of NMMO solution in cellulose fibers. Improving the porous characteristics of cellulose fibers not only effectively increased the NMMO retention value and swell extent but also shortened dissolution time without affecting the rheological properties of cellulose-NMMO solutions. Graphical abstract
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Food Analytical Methods
·
2026
·Vol. 19
·期 2
·112
·
IF 3
Tang Tingting,Chen Ziyi,Chen Shu,Zhang Peisheng,Zeng Rongjin,Hao Yuanqiang
This study developed and validated a photoelectrochemical (PEC) platform for hydrogen sulfide (H 2 S) analysis in alcoholic beverages by electrodepositing/annealing dense BiFeO 3 films on FTO and converting them in situ into BiFeO 3 /Bi 2 S 3 heterojunctions. Phase formation and elemental redistribution were verified by XRD, SEM/EDS, and XPS; UV–vis/Tauc and Mott–Schottky supported broadened visible absorption and a direct Z-scheme alignment, while EIS revealed a markedly lowered interfacial charge-transfer resistance. Under optimized conditions, the sensor delivered a linear range of 0.1‒100 μM with an LOD of 36 nM, along with good selectivity against common anions and thiol-bearing interferents and excellent cycling photostability. In real matrices, standard additions achieved recoveries of 99.2%‒103.5% in water; beer and red wine contained 1–2 μmol·L ‒1 H 2 S with 94.5%‒106.5% recoveries. These results demonstrated that in situ chemical conversion coupled with Z-scheme interfacial engineering offers a simple, robust, and general route to rapid, sensitive, and matrix-tolerant PEC monitoring of H 2 S in complex fermented beverages.
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Nano-Micro Letters
·
2026
·Vol. 18
·期 1
·233
·
IF 38.5
Jiang Yingqiao,Li Ming,Ye Jiaye,Dai Lei,Jiang Haoran,Wang Ling,He Zhangxing
A selectively regulating strategy for chemical environments of Mn ion activity donors
in LaMnO 3 perovskite can bidirectionally enhance vanadium reaction kinetics.
The key reactive sites and control steps of perovskite on vanadium redox reactions are
established based on electrochemical tests and theoretical calculation.
Sr and Ce doped LaMnO 3 as anode and cathode catalysts of the vanadium redox flow
battery (VRFB) , respectively, synergistically improves the VRFB’s energy storage
performance.
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TALANTA
·
2026
·
IF 6.7
Jingjing Yin,Yuehua Wang,Shanshan Zhu,Xiaoxue Liu,Yujie Sun,Hong Yang,Yifei Ma,Jinhua Liu
The development of wavelength-tunable fluorescence immunoassays for sensitive biomarker detection remains a significant challenge in clinical diagnostics. In this work, we present an HRP-induced in situ fluorogenic immunoassay platform based on the rapid reaction between p-phenylenediamine (PPD) analogues and 6-hydroxyquinoline (6-Hy). The proposed mechanism involves HRP-catalyzed generation of hydroxyl radicals from H 2 O 2 , which subsequently oxidize PPD to form fluorescent copolymer nanoparticles (FCNPs) with 6-Hy. By strategically modifying the PPD structure with various substituents, we achieved discrete and tunable emission of FCNPs, with maxima spanning from 380 to 600 nm (Δλ ≈ 220 nm). Using cardiac troponin I (cTnI) as a model antigen and zinc-coordination nanoparticles (ZnNPs) as carriers, the immunoassay demonstrated exceptional performance, with a wide dynamic range (0.5-125 ng/mL) and an ultralow detection limit (0.17 ng/mL) for cTnI. The platform was successfully validated in human serum samples, showing excellent correlation with clinical standards. This work not only establishes a novel strategy for wavelength-programmable immunoassays but also provides a versatile platform for advancing biomarker detection in clinical diagnostics.
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ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19
Zihui Liu,Wenting Feng,Jianhang Yang,Xinru Wei,Yunbo Zhang,Chenyu Ma,Yiming Sun,Han Wang,Haolin Wu,Debin Kong,Changming Mao
The escalating demand for high-energy-density storage has intensified research on Li-Cl 2 batteries, which exhibit ultrahigh energy density but suffer from rapid failure due to the poor ionic conductivity and mechanical fragility of naturally formed LiCl interphases on Li metal. Here, we design an organic–inorganic hybrid protective layer (Li 3 Sb/LiF/PVDF, denoted as LSLP@Li) via in situ interfacial engineering. This designed layer effectively isolates the Li anode from corrosive SOCl 2 electrolyte and suppresses parasitic reactions. The synergistic Li 3 Sb/LiF phase ensures high ionic conductivity and guides uniform Li deposition, while the flexible PVDF matrix accommodates cycling-induced volumetric strain. As a result, the LSLP@Li anode maintains structural integrity for over 48 h in corrosive electrolyte (<2 h for bare Li), enabling Li-Cl 2 batteries to maintain over 400 cycles at 1000 mA g −1 . The study advances the understanding of naturally formed LiCl layer on SOCl 2 -based battery and provide valuable strategy to achieve the interfacial stability.
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Advanced Healthcare Materials
·
2026
·
IF 9.6
Hai Zhou,Chaoyang Huang,Yanqi Chen,Tingzi Zhao,Fengyi Zhu,Gong Jun,Jinrong Zhang,Yingsong Pan,Qiulan Wen,Lei Yang,Huihui Zhang,Lianglong Chen
Diabetic wounds are characterized by persistent inflammation, impaired angiogenesis, and susceptibility to infection, posing significant clinical challenges. Here, we report an intelligent shape-memory sponge (P 1 A 3 @B-MOF) engineered for the programmable modulation of the diabetic wound microenvironment. The dressing consists of an interpenetrating network of oxidized pullulan and acellular dermal matrix, incorporating zeolitic imidazolate framework-8 (ZIF-8) metal–organic frameworks encapsulated with salvianolic acid B (SalB) via in situ self-assembly. This design enables exudate-triggered shape recovery and pH-responsive drug release, targeting the acidic pathological environment. We demonstrate that the released Zn 2+ and SalB exert synergistic effects: conferring broad-spectrum antibacterial activity, orchestrating macrophage repolarization from proinflammatory M1 to regenerative M2 phenotypes, and activating the hypoxia-inducible factor 1-alpha (Hif-1α)/vascular endothelial growth factor (VEGF) pathway to restore vascularization. In a diabetic rat model, the sponge accelerated wound closure with a 98.5% healing rate by day 14 and modulated collagen deposition via the transforming growth factor-β (TGF-β)/Smad signaling axis, thereby effectively mitigating scar formation. This integrated strategy offers a promising modality for restoring immune homeostasis and promoting functional skin regeneration.
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PHYTOMEDICINE
·
2026
·
IF 8.3
Yin-Chao Tong,Huan Lin,Yang Yang,Zhi-fu Zhou,Yi-Ning Zhang,Juan Wang,Wu-ren Ma,Yongsheng Wang,Wei-Min Zhang,Su-Zhu Qing
Background Antimicrobial resistance (AMR) infection is attracting increasing attention, especially superbug infections. As a result, finding ways to reduce AMR is essential. For the time being, natural compound therapy for reducing AMR is an ideal choice. Purpose This study aims to investigate the mechanism of magnolol reducing the AMR of E. coli in vitro and vivo . Methods The morphology and function of E. coli under magnolol treatment were assessed using a scanning electron microscope, qPCR, RNA-seq, and other methods. Moreover, the in vivo treatment effects of magnolol combined with antibiotics were evaluated by HE and IHC staining. Results In this study, we found that magnolol reduced the resistance of ESBL E. coli to the fourth-generation cephalosporin in vitro via two main mechanisms. Firstly, magnolol disrupts iron ion metabolism by increasing environmental iron uptake significantly (P ≤ 0.01), leading to a significant increase in intracellular ROS (P ≤ 0.01) and membrane damage. Secondly, magnolol significantly inhibits the relative mRNA expression of blaCTX-M-1 (P ≤ 0.01) and the CTX-M-1 enzyme activity in ESBL E. coli. Furthermore, we find that magnolol can inhibit ESBL E. coli in vivo by significantly reducing the TLR4-NFκB p65 pathway ( P ≤ 0.01). Conclusion In a word, our results indicate that magnolol is a natural antibacterial adjuvant with potent inhibitory activity against bacterial resistance and exerts this activity through multiple pathways, which has particular significance for the further study of the AMR mechanism.
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AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
·
2025
·
IF 5.3
Mingzhi Luo,Xiangrong Zhang,Jia Guo,Rong Gu,Youyuan Qin,Kai Ni,Lei Liu,Yan Pan,Jingjing Li,Honglei Shi,Linhong Deng
Bronchodilators that relax airway smooth muscle cells (ASMCs) are essential for treating constrictive airway diseases such as asthma. However, the existing bronchodilators are often unable to control symptoms of severe asthmatic patients, leaving a pressing need to search for alternatives. Recent studies indicate that the transmembrane mechanosensitive channel, Piezo1 may provide a novel target for bronchodilation as it mediates ASMCs relaxation via calcium signaling and activation of large-conductance calcium-activated potassium channels (BKCa), and Piezo1 specific agonist Yoda1 has been shown to reduce cell stiffness and traction force in cultured ASMCs after 24 h incubation. Thus in this study, we further explored the potential of Yoda1 for inducing rapid ASMCs relaxation and bronchodilation. We treated either cultured ASMCs or allergen-induced mouse models of asthma with Yoda1 at various doses, and then assessed the resulting variations in cell stiffness, traction force, and molecular signaling of cultured ASMCs, as well as in airway resistance of the mouse models. We found that exposure to Yoda1 rapidly decreased cell stiffness, traction force in association with induced calcium signaling and BKCa activation in cultured ASMCs, and reduced airway resistance in methacholine-challenged mice in a dose-dependent manner. These results indicate that chemical activation of Piezo1 with specific agonist Yoda1 was indeed capable of inducing bronchodilation by relaxing ASMCs, and thus provide insights into development of Piezo1 agonist-based novel bronchodilators for treating constrictive airway disorders such as asthma.
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Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
·
2017
·
IF 2.047
Hongbo Yang,Guihong Li,Zhu Rao,Feng Guo,Zhanbin Li,Feng Xie,Hong Tan
A systematic examination was conducted for the first time of a wide carbon-chain range of per- and polyfluoroalkyl compounds (PFASs) in 83 samples of edible vegetable and animal oils from Guiyang, China. The occurrence and levels of 18 PFASs in seven types of edible oil were analysed. Analytes were determined based on a simplified, sensitive and reliable solvent extraction and liquid chromatography-tandem mass spectrometry method. Ten target PFASs were found and the most frequently detected compounds with maximum concentration were PFOS (88%, 1.93 ng g–1), PFNA (55.4%; 6.76 ng g–1), PFHxS (39.8%; 0.36 ng g–1), and PFOA (16.9%; 0.15 ng g–1), respectively. The total PFASs concentrations ranged from 0.02 to 6.76 ng g–1, with a mean of 0.94 ng g–1. Significant differences of occurrence between vegetable oils and animal oils were demonstrated based on comparative analysis of the existing data. The investigation results showed that the effect of production reductions of PFOS and PFOA by regulatory was also reflected in edible oils. The dietary intakes of PFOS and PFOA for adults were estimated, which were lower than the available tolerable daily intake (TDI). Because of the global lack of food regulatory thresholds for most per- or polyfluoroalkyl compounds, it was difficult to draw any conclusion at this stage as to how human health is affected through exposure to these compounds. The baseline information of this study will assist in guiding the direction for future investigations and monitoring studies on occurrence, fate and human health-effect research of PFASs.
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JOURNAL OF HAZARDOUS MATERIALS
·
2017
·
IF 6.065
Xiulei Fan,Chao Wang,Peifang Wang,Bin Hu,Xun Wang
Most studies investigating the influence of TiO 2 NPs on heavy metal bioavailability have focused on the aqueous phase; however, few have examined the sediments containing more nanoparticles. Here, we investigated the effects of TiO 2 NPs on heavy metal bioavailability in C. fluminea in sediments. The interactions between the TiO 2 NPs and metals in sediments, the influence of TiO 2 NPs on metals levels in aqueous phase and geochemical speciation were also explored. The results indicated the large adsorption capacity of TiO 2 NPs and the strong adsorption affinity to metals caused the metals adsorbed on nanoparticles, which decreased the metals concentrations in water phase. Changes in metal speciation caused by metals in EXC, CAR, and IMO partly transported from sediments to TiO 2 NPs during the aging of sediments. Heavy metals contents in C. fluminea tissues were in the order of gill > visceral mass > mantle > foot and increased with the increasing TiO 2 NPs contents in sediments. TiO 2 NPs enhanced the bioavailability of metals in the speciation of EXC, CAR, and IMO in sediments by the Trojan horse effects. The results can facilitate a more realistic evaluation of the environmental risks of TiO 2 NPs to benthic organisms in heavy metal-contaminated sediments.
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JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2023
·
IF 6
Bingyang Li,Meiqian Chen
Massive spent ion exchange resins (SIERs) containing radionuclides are produced in nuclear power plants , which need to be treated reasonably. The migration mechanism of nuclides in SIER in both pyrolysis and gasification was evaluated from the chemical equilibrium analysis based on the Gibbs free energy minimization. The maximum volatility degrees of Co, Sr and Cs at 400–600 °C and 0.1 MPa were 0.01%, 0% and 0.1% in the pyrolysis . The maximum volatility degrees of Co, Sr and Cs were 0.015%, 0% and 100% at 600–1300 °C and 0.1 MPa in the gasification, and the steam concentration should be set mainly how to limit the volatilization of radionuclides . To reduce the volatility of nuclides as much as possible, the temperatures should be kept below 600 °C and 870 °C in the pyrolysis and gasification, respectively. The volatilization of Cs was greatly inhibited with lifting the pressure from 0.1 MPa to 1.5 MPa, which decreased from 0.103% to 0.007% in the pyrolysis (600 °C) and from 4.80% to 0.30% in the gasification (715 °C), respectively. Based on preventing the nuclides leakage, the negative pressure in the gasification should be controlled between 0.097 and 0.099 MPa. The volatilization of radionuclides was effectively weakened by adding a fixative, Zr(HPO 4 ) 2 ·H 2 O, since it could be helpful to reduce the gaseous cesium-based products in the pyrolysis and gasification. The volatility degree of Cs was close to 0 if Zr/Cs was great than or equal to 0.5. This study could provide basic data for the pyrolysis and gasification treatment of SIER.
研究领域:
核化学
·
环境工程
·
放射化学
·
废物处理
·
热力学分析
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PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
·
2020
·Vol. 37
·期 2
·1900445
·
IF 3.099
Artem Yakovliev,Tymish Y. Ohulchanskyy,Roman Ziniuk,Tereza Dias,Xin Wang,Hao Xu,Guanying Chen,Junle Qu,Anderson S. L. Gomes
In this work, the application of near infrared (NIR)-emitting NaYbF 4 :1%Tm 3+ @NaLuF 4 :30%Nd 3+ core–shell nanoparticles is reported for noninvasive probing and monitoring the temperature during photopolymerization of dental materials. When excited at 808 nm, the synthesized nanoparticles emit NIR photoluminescence (PL) with two distinctive peaks at 865 and 980 nm which correspond to radiative transitions from the doped Nd 3+ and Yb 3+ ions, respectively. Luminescence intensity ratio between these two bands is found to vary with temperature due to temperature-dependent electronic excitation energy transfer between Nd 3+ and Yb 3+ ions at the core/shell interface. This finding allows luminescence ratiometric evaluation of the in situ temperature during photopolymerization of resin cement (doped with nanoparticles) in a veneer placement procedure. In addition, the NIR emission also enables PL imaging of the distribution of the adhesive under the veneer. The results highlight that rare-earth ions–doped nanoparticles with both excitation and emission in the NIR spectral range are advantageous for both PL-based nanothermometry and imaging due to the reduced attenuation of NIR light by dental ceramics.
研究领域:
生物医学工程
·
牙体牙髓病学
·
纳米医学
·
光学成像
·
生物材料
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