Molecular Catalysis
·
2017
·
IF 0
Shuang Chu,Li’na Yang,Xingcui Guo,Linlin Dong,Xiufang Chen,Yaru Li,Xindong Mu
The catalytic behavior of a series of MFI catalysts with different Si/Al ratio (25–300) in the direct aqueous-phase hydrolysis of α-cellulose was studied. The effects ultrasonic pretreatment time, ZnCl 2 content, zeolite pore structure and acid-basic properties on catalyst activity and products distribution were systematically investigated. The results indicated that HZSM-5 with lower Si/Al ratio was beneficial for production of glucose and LA from α-cellulose. Ultrasonic pretreatment could decrease the degree of crystallinity and polymerization of α-cellulose, enhance the accessibility of acid sites and ZnCl 2 to the loosened amorphous regions of α-cellulose in water, and improve the hydrolysis efficiency of α-cellulose. The desilicated ZSM-5 (HZSM-5-DS(0.2)) showed much higher catalytic activities as compared to commercial ZSM-5 and α-cellulose conversion reached 76.5% over HZSM-5-DS(0.2) at 200 °C. Catalytic conversion of α-cellulose consisted of at least three important parallel reactions under the present hydrothermal conditions and a plausible pathway was proposed. Effective control of these reactions would be helpful to further maximize the target product yield during the catalytic conversion of α-cellulose.
✓ 已验证
DOI
Journal of the Taiwan Institute of Chemical Engineers
·
2023
·
IF 5.7
Dewei Wang,Zhaorui Sun,Xinliang Han
Background Aqueous non-metallic ammonium ions (NH 4 + ) have newly been developed as a promising charge carrier for electrochemical energy storage owing to their high safety, abundance, and tiny hydrated ionic size. Producing reliable electrode materials with excellent electrochemical performance, however, remains a significant issue. Methods we proposed a bidirectional chemical activation strategy, which effective coupling “in to out” and “out to in” etching manner, to synthesize foam-like porous carbon nanosheets (FCNSs) with the surface area much larger than that samples obtained from the unidirectional mode. Meanwhile, oxygen-deficient α‐MnO 2 nanorods can be rationally obtained through mild redox reaction, both of which display excellent capacitive performance in dilute (NH 4 ) 2 SO 4 electrolyte (0.5 M). Significant findings the as-synthesized FCNSs and oxygen-deficient α‐MnO 2 nanorods can deliver a specific capacitance of 257.5 F g −1 and 525.1 F g −1 , respectively, demonstrating their huge potential to assemble ammonium-ion hybrid supercapacitor (A-HSC). Benefitting from the feasible electrochemical performance for both anode and cathode, the resulting A-HSC displays a specific capacitance of 180.8 F g −1 (calculated based on both anode and cathode) within 0–1.6 V, and a low self-discharge rate, which outperforms the state-of-the-art A-HSC devices. Importantly, the energy storage mechanism has been elucidated from several ex-situ characterizations.
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Xin Cheng,Yan Huang,Chao Yuan,Ke Dai,Hong Jiang,Jimei Ma
An ultrasensitive colorimetric method for α-glucosidase sensing based on iodine-mediated etching of gold nanorods (AuNRs) was developed. In this method, 2- O -α- d -glucopyranosyl- l -ascorbic acid (AA-2G) was used as an enzymatic substrate. The hydrolysate ascorbic acid in situ reduced KIO 3 to I 2 , which subsequently etched the AuNRs. A blue-shift of the localized surface plasmon resonance (LSPR) absorption of AuNRs was clearly observed by UV–vis spectroscopy and reflected with visual color changes. The shift showed a good linear relationship with the concentration of α-glucosidase during 2.5–45 U/L and a low α-glucosidase detection limit of 0.5 U/L was provided. This strategy was featured with low cost, simplicity, excellent sensitivity, high selectivity and successfully applied in the α-glucosidase inhibitor screening with Chinese Wolfberries as candidates.
✓ 已验证
DOI
高影响因子
GREEN CHEMISTRY
·
2019
·Vol. 21
·期 19
·5336-5344
·
IF 9.405
Da Yang,Huan Liu,Lei Liu,Wen-Di Guo,Yong Lu,Ye Liu
An amphiphilic tri-functional ligand (L1) containing a Lewis acidic phosphonium cation, a phosphino-fragment and a hydrophilic sulfonate anion (–SO3−) enabled Pd(OAc)2 to efficiently co-catalyze the hydroxycarbonylation of terminal alkynes towards α,β-unsaturated carboxylic acids. These incorporated functional groups synergistically promoted the reaction, which proved more effective than the ligands lacking –SO3− and/or phosphonium and the mechanical mixtures of the individual functional groups independently. The molecular structure of Pd-L1 indicated that –SO3− in L1 served as a secondary O-donor ligand with reversible coordinating ability, cooperating with the phosphino-fragment to stabilize the Pd-catalyst. The in situ FT-IR analysis verified that the formation and stability of Pd–H active species in charge of hydroxycarbonylation were dramatically facilitated by the presence of L1. It was believed that, over the L1-based Pd-catalyst, H2O was cooperatively activated by the Lewis acidic phosphonium via “acid–base pair” interaction (H2O → P(V)+) and by the hydrophilic SO3−via hydrogen bonding (SO3−⋯H2O), giving rise to the formation of dimeric and mono-nuclear Pd–H species driven by reversible SO3−-coordination. In addition, the L1-based Pd-catalyst could be immobilized in the ionic liquid [Bmim]NTf2 for six-run recycling uses without obvious activity loss and detectable metal leaching.
✓ 已验证
DOI
高影响因子
Food Chemistry-X
·
2025
·
IF 8.2
Jing Liang,Jiayan Xie,Yue Gu,Jianhua Xie,Yi Chen,Bing Zheng,Yue Qiu,Xiaobo Hu,Qiang Yu
Vigna umbellata is an important homologous medicinal and food legume, and its fruit is rich in polyphenols. Acidic, alkaline (highest yield) and enzymatic methods were used to release bound polyphenols from rice bean skin dietary fiber. 44 compounds were identified from the alkaline hydrolysis products. With the increase of polyphenol concentration within a specific range, the scavenging rate of DPPH• and ABTS + • radicals and the reduction ability of ferric ions were increased. Rice bean skin dietary fiber bound polyphenols (RBSDF-BP) showed significant α -glucosidase inhibitory activity. The results showed that Hydrogen bonding and hydrophobic forces were the binding forces for RBSDF-BP to form a stable polyphenol-enzyme complex with α -glucosidase. Molecular docking revealed that the three polyphenols of RBSDF-BP had a strong affinity for the active site in the hydrophobic cavity of the enzyme. This study provides valuable discoveries for the potential application of RBSDF-BP as natural inhibitors of α -glucosidase. Chemical compounds Protocatechuic acid (PubChem CID: 72); Malic acid (PubChem CID: 525); Isoferulic acid (PubChem CID: 736186); p-Hydroxybenzoic acid (PubChem CID: 135); Citric acid (PubChem CID: 311), (+)-Catechin (PubChem CID: 9064), Fumaric acid (PubChem CID: 444972), Gallic acid (PubChem CID: 370), Azelaic acid (PubChem CID: 2266), (−)-Epicatechin (PubChem CID: 72276).
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BBA Advances
·
2025
·
IF 3
Xueliang Lu,Xu Wang,Mingyue Xiong,Pengbo Wang,Yingkang Zhu,Xiangyu Wang,Xia Liu,Hanjie Yu,Ruiyu Liu
Purpose Osteonecrosis of the femoral head (ONFH) is one of the most common and devastating articular cartilage diseases worldwide. The role of glycosylation in cartilage degeneration of ONFH is not yet fully understood. Patients and methods The expression of glycogens in cartilage from ONFH patients was determined using our own whole-genome expression dataset. Moreover, the altered glycosylation associated with ONFH cartilage and methylprednisolone (MPS)-induced cell models was investigated by lectin microarrays. The synthesis of α-2,3 sialylation was repressed by silencing ST3GAL2, and the effect of α-2,3-sialylation on ONFH-associated molecular events was assessed. Results Our findings revealed that the expression of 18 glycogens (including ST3GAL2) were significantly changed in ONFH cartilage compared with those in fracture control cartilage. Moreover, the level of α-2,3 sialylation, which is catalyzed by ST3GAL2, was significantly increased in ONFH cartilage and cell models compared to their corresponding controls. Silencing the expression of ST3GAL2 not only reduced the level of α-2,3 sialylation but also suppressed the expression of proinflammatory cytokines, reduced apoptosis-related proteins, and inactivated the NF-κB signaling pathway. Conclusion Our study highlighted the important role of α-2,3 sialylation in the development of ONFH, providing valuable insights into the molecular mechanisms underlying the pathogenesis of ONFH.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Tao Guo,Danjun Mao,Xiufeng Lu,Wenhao Ma,Heyun Fu,Huan He,Cheng Sun,Shourong Zheng,Zhifeng Jiang,Xiaolei Qu
Inadequate contact interface, lack of direct electron-transfer paths and low substrate affinity are considered as the main obstacle inhibiting the heterostructure activity for the sustainable photosynthesis of value-added fine chemicals. Herein, a novel 0D/2D Step-scheme (S-scheme) α-Fe 2 O 3 /PbBiO 2 I (FO/PBOI) composite with abundant interface Fe O bonds were initially synthesized via an in-situ growth approach. The created built-in field as a powerful driving force, efficiently steering the migration of photogenerated electrons. The interfacial Fe O bonds act as atomic-level transfer highway, lowering charge transfer energy barrier between the interfaces and further accelerating the S-scheme spatial charge separation. Moreover, the Fe O bonds bridged FO/PBOI can effectively enhance the activation of O 2 and benzylamine, significantly reducing the dehydrogenation barrier for the rate-limiting C 6 H 5 CH 2 NH* intermediate. The optimized FO/PBOI exhibits remarkably improved catalytic activity and general applicability for the dehydrocoupling of primary amines to imines. This work offers an atomic-scale perspective on precise charge flow steering based on interface bond for advanced organic transformations.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemical and Biological Technologies in Agriculture
·
2025
·Vol. 12
·期 1
·1-22
·
IF 5.2
Xia Lunbin,Chen Cunwu,Bi Shaoshuai,Zhang Yafei,Chen Naidong,Feng Jing
Background In recent years, the biological activities of polysaccharides derived from Chinese herbal medicones have garnered increasing attention. Polygonatum cyrtonema Hua, a widely used traditional Chinese medicinal herb, possesses significant healthcare value. However, the structure–activity relationship between polysaccharide structures and biological functions remains to be fully elucidated. Methods Crude Polygonatum cyrtonema Hua polysaccharides (PCHP) were extracted using hot water extraction followed by alcohol precipitation. The extract was subsequently purified through DEAE seplife FF chromatography, yielding two franctions: PCHP-1 and PCHP-2. Because of the highest content and the better solubility, PCHP-1 was further purified using Sephacryl S-400HR column chromatography to obtain a purified fraction designated as PCHP-1A. Subsequently, The structural characteristics of PCHP-1A were comprehensively analyzed through monosaccharide composition analysis, scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), methylation analysis, and nuclear magnetic resonance (NMR) spectroscopy. Additionally, the antioxidant and hypoglycemic activities of PCHP-1A were evaluated though in vitro experiments. Results Structural analysis revealed that PCHP-1A, with an average molecular weight of 2.90 × 10 4 Da, is comprised of fructose (Fru), glucose (Glc), galactose (Gal), mannose (Man), arabinose (Ara) and rhamnose (Rha). PCHP-1A exhibited a compact and curly spherical molecule conformation, and SEM analysis revealed its smooth, porous, clastic or lamellar microstructure. Comprehensive FT-IR, GC–MS, and 1D/2D NMR analyses indicated that the main chain of PCHP-1A consists of → 1)-β- d -Fru f -(2 → , → 1,6)-β- d -Fru f -(2 → , and → 6)-α- d -Glc p, with branch chains primarily composed of β- d -Fru f -(2 → linked at the O -6 position of → 1,6)-β- d -Fru f -(2 →. Biological activity assays demonstrated that at a concentration of 4.0 mg/mL, PCHP-1A exhibited a DPPH scavenging rate of 56.92 ± 1.42% and an inhibitory capacity against · OH radicals of 23.27 ± 1.80 U/mL. Furthermore, PCHP-1A showed significant hypoglycemic activity, with an IC 50 value of 5.15 ± 1.09 mg/mL. Conclusions This study successfully isolated and purified polysaccharide from Polygonatum cyrtonema Hua, elucidated its fundamental structure, and investigated its antioxidant and hypoglycemic activities. The findings provide a theoretical foundation for understanding the structure–activity relationship of the polysaccharide and suggest that Polygonatum cyrtonema Hua polysaccharide may be a natural potential antioxidant and hypoglycemic agent. Graphical
✓ 已验证
产品关联
DOI
高影响因子
IUCrJ
·
2021
·
IF 4.769
Jiawei Lin,Peng Shi,Ying Wang,Lingyu Wang,Yiming Ma,Fei Liu,Songgu Wu,Junbo Gong
Template design on polymorph control, especially conformational polymorphs, is still in its infancy and the result of polymorph control is often accidental. A method of regulating the crystallization of conformational polymorphs based on the crystal structure similarity of templates and the target crystal form has been developed. Crystal structure similarity was considered to be able to introduce lattice matching (geometric term) with chemical interactions to regulate conformational polymorph nucleation. The method was successfully applied to induce the crystallization of DA7-II [HOOC–(CH 2 ) n −2 –COOH (diacids), named DA n , where n = 7, 9, 15, 17 and II represents the metastable polymorph] on the surface of DA15-II. An analogous two-dimensional plane – the (002) face of both DA15-II and DA7-II – was firstly predicted as the epitaxially attached face with similar lattice parameters and the strongest adsorption energy. The powder DA15-II template with the preferred orientation face in (002) presented much stronger inducing DA7-II ability than the template with other preferred orientation faces. The epitaxial growth of DA7-II on DA15-II through an identical (002) face was clearly observed and verified by the single-crystal inducing experiments. The molecular dynamics simulation results demonstrated that the strong interactions occurred between DA7 molecules and the (002) face of DA15-II. This method has been verified and further applied to the crystallization of DA7-II on the surface of DA17-II and DA9-II on the surface of DA15-II. This study developed a strategy based on structure similarity to regulate the conformational polymorph and verified the significant role of lattice matching and chemical effects on the design and preparation of templates.
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Huajie Lan,Lei Tian,Wenfeng Wang,Yuan Li,Shumin Han,Lu Zhang
The currently used β -Ni(OH) 2 for alkaline nickel batteries are falling short of higher capacity demand. In contrast, α -Ni(OH) 2 with high theoretical capacity can address this need. However, the α -Ni(OH) 2 suffers from poor stability and intrinsic low electrical conductivity. Herein, we designed La/Ce-doped spherical α -Ni(OH) 2 and study the effect of La/Ce on the structure and electrochemical properties of α -Ni(OH) 2 . The increased specific surface area of the α -Ni(OH) 2 with La/Ce doping reduces the electron transfer resistance. The La/Ce-doped α -Ni(OH) 2 with 2 at% La (Ni-La-2) and 3 at% Ce (Ni-Ce-3) doping deliver high capacities of ∼365 mAh g –1 and ∼373 mAh g –1 , respectively, which is only 309 mAh g –1 for the pure α -Ni(OH) 2 . Meanwhile, the La/Ce-doping stabilizes the structural robustness of the α -Ni(OH) 2 during cycling. Notably, Ni-La-2 shows a superior stable cycling life with a capacity retention of ∼95 % after 400 cycles, which is ∼20 % higher than that of pure α -Ni(OH) 2 .
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Yingcai Wang,Min Chen,Can Wang,Xiaoyang Meng,Weiqiu Zhang,Zefang Chen,John Crittenden
Methylisothiazolinone (2-methyl-4-isothiazolin-3-one) (MIT) is a commonly used biocide in wastewater treatment processes. Residual MIT in wastewater leads to high environmental risks and toxicity. The degradation of MIT via electrochemical oxidation, including kinetics, energy efficiency, oxidation mechanism and degradation pathway, was investigated in this study. Findings from energy and cost evaluation by using electrochemical technology were compared with those of other technologies. Experimental results indicate that electrolyte, current density and initial concentration can significantly affect MIT degradation. The lowest electrical energy per order was less than 3.85 kWh m −3 when NaCl was used as the electrolyte. Electrochemical degradation is advantageous because it can be easily applied without adding chemicals into wastewater and has relative low costs. The oxygen evolution, production of recalcitrant byproducts, and the mass transfer limitation resulted in the decrease of instantaneous current efficiency and mineralization current efficiency. Electron efficiency analysis demonstrated that 68.8% of the electrons used for MIT oxidation were effectively utilized to mineralize MIT into CO 2 . The proportion of direct and indirect oxidation of MIT during electrochemical degradation was quantitatively determined as 37.7% and 62.3%, respectively. HO was the most effective species for MIT degradation. MIT degradation pathway was proposed, in which the C C bond in MIT was broken down. C 3 H 7 NOS and C 3 H 7 NO 4 were detected, indicating the occurrence of ring opening reaction. Sulfur was oxidized into SO 4 2− and cleaved from C 3 H 7 NOS.
✓ 已验证
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2020
·
IF 7.183
Xiaotai Zhang,Hai Huang,Xiaoming Li,Jian Wang,Yangyang Wei,Huifeng Zhang
Active chlorine-vulnerability is the Achilles' heel for polyamide thin film composite (PA-TFC) reverse osmosis (RO) membranes during water desalination and/or purification. Chlorination disrupts the delicate PA skin layer on porous support, resulting in significantly deteriorative membrane permselectivity and rising maintenance cost. Inspired by the superior antioxidative capacity of biologically endogenous α-lipoic acid (LA), this work was dedicated to tailoring a chlorine-resistant RO membrane with LA sacrificial unit on the surface. It was evidenced that the characteristic dithiolane within LA preferentially reacted with active chlorine in feedwater, and the intimal PA selective layer was thus safeguarded from chlorine-triggered oxidation . The modifier was pre-assembled with LA and polyethylenimine (PEI) as the mediator, subsequently tethered onto membrane surface via one-step chemical coupling without any catalysts. A pretty balance between membrane permselectivity and grafted modifier amount was achieved via regulating the modifier concentration. The modified membrane exhibited significantly ameliorative chlorine-resistance relative to the pristine one, with normalized salt rejection still remained (99.3 ± 0.6)% and only (17 ± 5)% final flux loss after a rigorous static chlorine exposure of 8000 ppm·h under acidic condition (confidence level, P = 95%). The electronic energy differences of chlorination-involved chemical procedures were determined by density functional theory (DFT) calculation, and an energy-favored three-stage tandem oxidation mechanism of LA moiety was proposed. Accordingly, up to 5 equiv. of active chlorine can be captured by a single sacrificial unit. Such intrinsically high chlorine-consumption efficacy of LA-based sacrificial layer would retard the chlorination saturation that commonly invalidates sacrificial layers. This bioinspired work shed light on a novel, facile, and effective anti-chlorine strategy for PA-TFC RO membrane to maintain the stability of service performance.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）