INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
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IF 7.7
Yinan Qiu,Jia Gao,Wenhui Chu,Shanshan Xia,Chen Huang,Huayue Zhu,Xiaolong Sun,Yongqian Fu
Acute lung injury (ALI) is a critical respiratory syndrome significantly impacting patient health. Tetrastigma hemsleyanum Diels et Gilg (Sanyeqing, SYQ) is a traditional Chinese medicine and its polysaccharides (SYQP) have demonstrated efficacy in counteracting lipopolysaccharide-induced ALI. This study characterized the structure of SYQP and synthesized the SYQP@ZIF-8 composite using biomimetic mineralization, evaluating encapsulation and release efficiency. The biocompatibility of SYQP@ZIF-8 in vitro was assessed by the CCK-8 colorimetric assay and hemolytic activity. Inflammatory cytokine was measured to evaluate the therapeutic effect. The efficacy of SYQP@ZIF-8 in lung injury was assessed using a mice ALI model. Characterization showed SYQP as a homogeneous α-type polysaccharide, comprising galactose, mannose, glucuronide, glucose, galacturonide, and arabinose, with a molecular weight of 516.94 kDa. SYQP@ZIF-8 exhibited high encapsulation rate (> 90 %), rapid pH-responsive release (within 60 min up to ~100 %), low toxicity and favorable hemolytic characteristics. Furthermore, it demonstrated reduced inflammatory cytokine secretion compared to SYQP, along with a superior inhibitory effect. The outcomes of in vivo experiments, including a decrease in the W/D ratio and LDH activity, further confirmed the efficacy of SYQP@ZIF-8 in treating LPS-induced ALI. In conclusion, SYQP@ZIF-8 released SYQP in acidic inflammatory conditions, outperforming SYQP alone in treating ALI.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2024
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IF 4.1
Xingnian Duan,Jianmei Cen,Xiaoyu Qiu,Xixiang Liu
The development of high-performance and cost-effective electrocatalysts for oxygen evolution reactions (OER) is key to renewable energy conversion and storage technologies. In this paper, a hierarchical Co(OH) 2 -MoO 3 nanosheets with petal-like architecture was prepared by a simple one-step hydrothermal method using ZIF-67/NF as a precursor, and it was used as a direct electrocatalyst for OER. Notably, this petal-like Co(OH) 2 -MoO 3 /NF layered nanosheets not only prevent the agglomeration of nanostructured material , but also facilitate the complete penetration and diffusion of electrolyte. In addition, due to the strong electronic interaction between Co(OH) 2 and MoO 3 in the Co(OH) 2 -MoO 3 /NF system, Co(OH) 2 -MoO 3 /NF exhibits excellent electrocatalytic OER performance. It has a low overpotential of 273 mV at 10 mA cm −2 and excellent stability. This study provides a simple and effective strategy for the rational design and structural evolution of MOF-derived materials to achieve inexpensive and effective electrocatalysis.
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Advanced Science
·
2025
·
IF 14.1
Zhengrong Chen,Wenxin Yang,Yong Tang,Qianqian Dong,Kui Huang,Jiulin Tan,Jie Zhang,Juan Cai,Qixiu Yu,Qijie Dai,Jianzhong Xu,Shuquan Guo,Ce Dou,Fei Luo
Osteoporotic bone defects are challenging to repair due to imbalances in bone resorption and formation, coupled with insufficient vascularization. To address these issues, it develops a trifunctional hydrogel (SF-ZIF@NA) designed to selectively inhibit osteoclast activity and enhance vascularized bone regeneration. By enzymatically removing sialic acid, SF-ZIF@NA prevents precursor osteoclasts (pOCs) from fusing into bone-resorbing mature osteoclasts (mOCs), thereby preserving pOCs and their anabolic functions. Additionally, the hydrogel releases Zinc ion (Zn 2 ⁺) in response to acidic conditions, promoting osteogenesis and angiogenesis. In vitro results confirmed that SF-ZIF@NA impedes osteoclast fusion, enhances platelet-derived growth factor-BB (PDGF-BB secretion from pOCs, and activates the FAK (focal adhesion kinase) signaling pathway to stimulate vascularized bone formation. In osteoporotic bone defect models, SF-ZIF@NA accelerated bone repair with increased bone density and vascularization. These findings demonstrate that SF-ZIF@NA offers a targeted and multifunctional strategy for osteoporotic bone regeneration by concurrently modulating osteoclast activity and promoting angiogenesis.
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PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
·
2024
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IF 6.9
Liusha Cen,Fan Yu,Shixue Liu,Chengcai Li,Wangyong Jin,Chenliang Wang,Hailin Zhu,Yuhai Guo
The technology that catalyst activated perxymosulfate (PMS) has been widely used in the decomposition of organic pollutants. We prepared Zn and Co-based ZIF and obtained C-doping Co 3 O 4 / ZnO heterojunction after pyrolysis. C-doping Co 3 O 4 / ZnO heterojunction with cage core-shell structure was loaded on the polyvinylidene fluoride (PVDF) membranes with a layered porous structure by solvent-assisted nanoparticle embedding (SANE) method, where the carmine degradation reached 99.6 % by MC-430 activated Perxymosulfate (PMS) within 10 min. The influencing factors (such as the pyrolysis temperature, PMS dosage, and dye concentration) on OFX degradation were observed, and MC-430 exhibited good tolerance for these factors and a wide range of solution hydrogen ion concentrations (pH= 4–10). The strong reusability and stability analysis showed that the carmine degradation of the MC-430/PMS system changed minorly (from 99.6 % to 97.7 %) in 5 consecutive cycles without any treatment. The degradation mechanism was confirmed by capture experiments, in which the non-free radical path was the main one and the free radical path was the auxiliary one. Moreover, structure characterizations and density functional theory calculations verified that doped C sites provided a channel for electron transfer from Zn sites to Co sites, which increased the generation rate of reactive oxygen species (ROS) and prolonged the catalyst life. This work provides a new method for the preparation of nonmetallic doping bimetallic strong coupling catalysis.
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JOURNAL OF SOLID STATE CHEMISTRY
·
2024
·
IF 3.2
Le Chen,An Xie,Nan Zhang,Jianjun Yin,Qun Chen,Mingyang He,Zhihui Zhang
Zeolitic-Imidazolate Framework 8 (ZIF-8), a porous crystalline absorbent, could be synthesized from the coordination reaction of zinc ions and 2-methylimidazole (2-mIM). ZIF-8 has a large specific surface area and a high adsorption capacity for n -hexane ( n HEX). However, ZIF-8 suffers from low selectivity for both linear and mono-chain alkanes. Therefore, ZIF-8 was modified through 2-mIM ligand being partly replaced by 2-nitroimidazole (2-nIM) through Vapor-Phase post-synthesis modification. The modified materials were denoted as ZIF-8-2-nIM-X (X = 24h, 48h, 72h). ZIF-8-2-nIM-X has a higher specific surface area and better thermal stability than ZIF-8. Further thermodynamic and kinetic calculations show that the affinity of hexane isomers on ZIF-8-2-nIM-X is spontaneous physical adsorption combined with an exothermic process. In contrast, kinetic studies show that the adsorption of hexane isomers on ZIF-8-2-nIM-X is a pseudo-second-order kinetic model. The batch and dynamic adsorption and separation properties of ZIF-8-2-nIM-X for hexane isomers were studied. The results of the one-component vapor adsorption equilibrium experiment show that ZIF-8-2-nIM-72h has the best adsorption separation coefficient at 293 K. The adsorption capacity of n HEX and 3-methylpentane (3MP) were 211.63 mg/g and 33.91 mg/g, respectively. Compared with ZIF-8 (selectivity coefficient: 1.08), the adsorption selectivity coefficient of the modified material is greatly improved. The adsorption selectivity coefficient of n HEX/3MP is 6.24 (ZIF-8-2-nIM-72h).
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Yi Zheng,Jinyue Song,Junzhou Men,Hui Xian,Yating Wang,Tao Jiang
Metal organic frameworks (MOFs) are regarded as the promising potential photocatalytic materials because of its high specific surface area , regular morphology and highly adjustable structure. Herein, introducing different addition percentage of 1-vinylimidazole to two-dimensional zeolite imidazole framework (ZIF-L) with leaf-shaped morphology was successfully prepared via water-assisted strategy and applied in the photocatalytic hydrogen evolution experiments. The results indicate that VZ-12 shows the highest photocatalytic activity with hydrogen production rate of 162.7 μmol g −1 h −1 , which is 3 times than that in VZ-0 (pure ZIF-L, 56.33 μmol g −1 h −1 ) under simulated sunlight. The enhanced performance is ascribed to the increased specific surface area observed via BET, narrow band gap ( E g ) explored through UV–vis DRS and decreased recombination of photo-generated charge carriers measured by photoluminescence (PL). In a word, the effort of our study provides a new idea for developing and fabricating efficient hydrogen production photocatalyst via water splitting.
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RARE METALS
·
2025
·
IF 11
Guo Jing,Mu Zhi-Mei,Yu Jing,Sun Guan-Liang,Hou Lin-Rui,Qiao Xue-Zhi,Yang Shi-Kuan,Zhang Xing-Shuang,Xu Guan-Chen,Liu Guo-An,Yang Fan,Yuan Chang-Zhou,Liang Xiu
Metal–organic framework materials exhibit considerable potential as molecularly selective surface-enhanced Raman spectroscopy (SERS) substrates because of their microporous structures, which enrich small molecules while excluding larger ones. In this study, we develop a template-assisted chemical-etching strategy to prepare layered tuneable SERS substrates based on hierarchical porous zeolitic imidazolate framework-67 (HP-ZIF-67) with a rhombic dodecahedral structure. The synergistic SERS enhancement mechanisms of HP-ZIF-67, which combine electromagnetic (EM) and chemical (CM) effects, were systematically studied through numerical simulations and experiments. Calculations revealed that under 633-nm laser excitation, the contributions of the EM and CM effects to the total SERS enhancement factor of HP-ZIF-67 were 60% and 40%, respectively. The hierarchical porous structure enhanced the fluid-flow flux over the microporous ZIF-67 because the increased pore radius reduced the viscous resistance and facilitated rapid molecular transport through the interconnected macro-meso-channels. Precise modulation of the CM and EM effects, combined with enhanced mass transfer, facilitated the development of HP-ZIF-67 and HP-ZIF-67@Au as efficient SERS sensors. An investigation of the relationship between pore-size distribution and EM effects revealed the pivotal role of light confinement by whispering-gallery-mode microcavities in enhancing the SERS performance. The optimised HP-ZIF-67@Au composites functioned as flexible and highly sensitive in situ SERS sensors for gases and liquids, including volatile organic-compound gas and liquid-pesticide residues. This study introduces a novel design concept and provides a robust theoretical foundation for the future development of exhaled-breath point-of-care diagnostic devices and sweat-based wearable biomedical sensors. Graphical abstract
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Peiqing Zhang,Sihang Li,Fan Xiao,Yongfang Xiao,Yi Zhang,Zhongguo Shan,Zhenyu Li,Haihua Wang
Membrane distillation (MD) represents a promising advance in wastewater purification, contributing to the mitigation of water scarcity. Hydrophobic poly(vinylidene fluoride) (PVDF) microporous membrane is susceptible to wetting by low surface tension substances, leading to fouling. To address this, PVDF membrane was superhydrophobically modified using modified ZIF-8 to obtain two composite membranes, AZ/PVDF and Z@C/PVDF. AZ/PVDF and Z@C/PVDF composite membranes were prepared by coating more dispersible APTES-ZIF-8 and ZIF-8@MWCNT, respectively, onto the surface of PVDF membrane. The hydrophobicity of the composite membranes was regulated by silane types, fluorination methods, and fluorination time, resulting in reduced surface roughness and increased surface energy. The contact angles of AZ/PVDF and Z@C/PVDF were 154.2 ± 3.4° and 156.8 ± 4.2°, respectively. Both AZ/PVDF and Z@C/PVDF membranes demonstrated outstanding mechanical, thermal, and chemical stability. AZ/PVDF and Z@C/PVDF membranes outperformed PVDF membrane, extending operation times by 2 h and 3 h, respectively, without obvious NaCl crystals. Furthermore, Z@C/PVDF membrane exhibited superior resistance to wetting by SDS than AZ/PVDF and PVDF membranes, treating pickle brine via the direct contact MD (DCMD) process with a recovery rate of 30.2 % within 10 h. Overall, this research offers a promising approach to fabricating superhydrophobic composite membranes for high-salt brine treatment via DCMD.
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Journal of Water Process Engineering
·
2025
·
IF 6.7
Mei Dong,Qiguang Cao,Song Li,Kebin Li
Designing stable and efficient heterogeneous catalysts for peroxymonosulfate (PMS) activation remains a critical challenge in advanced oxidation processes. Herein, we prepared a polyvinylpyrrolidone (PVP)-modified MIL-101(Fe)@CoZn-ZIF (PVP-MCZ) core-shell nanocomposite that synergistically combined enhanced catalytic activity with exceptional stability. The PVP-MCZ catalyst achieved complete degradation of 4-nitrophenol (4-NP) (20 mg/L) within 15 min, while suppressing metal leaching (<0.5 mg/L). Comprehensive characterization (XPS, EPR) revealed a dual-pathway mechanism: (i) radical-dominated SO 4 − generation via Co 2+ /Co 3+ and Fe 2+ /Fe 3+ redox cycling, and (ii) non-radical 1 O 2 production from PMS self-decomposition. This work provides a scalable strategy to design MOF-based catalysts for sustainable water remediation.
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ChemistrySelect
·
2025
·Vol. 10
·期 28
·e00259
·
IF 2
Bo Yang,Hai Xing,Yang Xia,Xin Wang,Ningning Liu
Graphical ZIF-8 was synthesized through an in-situ growth method within a PVDF membrane matrix. The PVDF/ZIF-8 composite membrane was subsequently prepared via the phase inversion method using immersion precipitation. The ZIF-8 particles were uniformly distributed in the PVDF/ZIF-8 composite membrane. The widespread use of organic dyes in industrial processes has led to increasing environmental pollution due to the discharge of dye-contaminated wastewater, necessitating more efficient dye removal methods. In this study, a poly(vinylidene fluoride) (PVDF)/ZIF-8 composite membrane was fabricated via a phase inversion method using immersion precipitation, with ZIF-8 synthesized via in-situ growth within the membrane matrix. The composite membranes were thoroughly characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and thermogravimetric analysis (TGA). The ZIF-8 particles were uniformly distributed in the PVDF/ZIF-8 composite membrane. The adsorption performance of the PVDF/ZIF-8 composite membrane was evaluated for methyl green (MG) removal. At 313 K with an adsorbent dose of 10 mg, the membrane exhibited an adsorption capacity of 172.30 mg g⁻¹ and a removal ratio of 87.21%, demonstrating that the incorporation of ZIF-8 significantly enhanced adsorption performance. Adsorption isotherm studies revealed that the process followed the Freundlich model, while kinetic analysis indicated a pseudo-second-order mechanism. Additionally, thermodynamic investigations suggested that the adsorption was endothermic and spontaneous. The major driving force for adsorption was identified as electrostatic interactions between the dye and the membrane. These findings highlight the potential of PVDF/ZIF-8 composite membranes for effective dye removal from wastewater.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Xiru Zhang,Manyan Qiu,Yiyi Zhang,Qianyu Zhao,Bo Qu,Wei Zhang,Xianlong Zhang,Yujun Jiang
Foodborne pathogens have posed a great threat on food safety and public health, and thus the development of accurate and sensitive methods for the detection of foodborne pathogens is of great significance. In this study, a novel Pyrococcus furiosus Argonaute ( Pf Ago) biosensing platform based on metal-organic framework (MOF) nanozyme (namely AgoZyme) was developed for the detection of Salmonella typhimurium . Inspired by the catalytic characteristics of horseradish peroxidase, we synthesized a Hemin@ZIF-90 nanozyme with peroxidase-like activity by encapsulating hemin into a zeolitic imidazolate framework-90 through a self-assembly strategy. By integrating the specific recognition and cleavage capabilities of Pf Ago with the highly catalytic performance of Hemin@ZIF-90, the AgoZyme biosensor exhibited excellent detection sensitivity and specificity. This biosensor had a limit of detection of 1 CFU/mL in a linear range from 10 1 to 10 8 CFU/mL. This work provided a new insight for designing and developing novel biosensors for food safety detection.
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ChemCatChem
·
2025
·
IF 3.9
Tianao Zhang,Haolong Huang,Yunchong Wang,Qianqian Zhao,Rui Han,Qingling Liu
Graphical CoO x /BCN catalyst with dual active sites was successfully synthesized. This catalyst exhibits excellent selectivity (99%) and a cyclic carbonate yield (98%) in the CO 2 cycloaddition reaction with the nucleophilic reagent KI under solvent-free and mild reaction conditions. This catalyst also has good stability and reusability, providing a new direction for the design of high-performance CO 2 cycloaddition catalysts. The carbon dioxide (CO 2 ) cycloaddition reaction provides an efficient route to achieve resource utilization of CO 2 . However, the inherent chemical stability of CO 2 itself hinders its efficient transformation into cyclic carbonates. Herein, the CoO x /BCN catalyst was successfully prepared by a simple deposition method. The CoO x /BCN exhibited excellent catalytic performance in the CO 2 cycloaddition reaction synergistically catalyzed with the nucleophilic reagent KI under solvent-free and mild reaction conditions (80 °C, 0.8 MPa, 6 h). The yield of cyclic carbonate was 98% and the selectivity was 99%, which was significantly superior to CoO x /CN catalyst (with a cyclic carbonate yield of 73.7%). Furthermore, after six cyclic reactions, CoO x /BCN still maintained a yield of over 93%. It was found that after boron (B) was doped into graphitic carbon nitride (g-C 3 N 4 ), the generated ─NB(OH) 2 group on CoO x /BCN effectively activated the epoxide. Importantly, the interaction between B-doped g-C 3 N 4 and CoO x induced the generation of abundant oxygen vacancies, which provided sufficient active sites for CO 2 adsorption and activation. In addition, carbonates were identified as the main reaction intermediates by in situ DRIFTS, and the possible reaction pathways of the CoO x /BCN catalyst were proposed. Therefore, this work provides new idea for the design of catalysts for CO 2 cycloaddition.
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