CERAMICS INTERNATIONAL
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2022
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IF 5.532
Ziwei Yue,Xiaoliang Ji,Wei Zhou,Zhihao Ji,Fu Guo
Due to a lower intrinsic thermal conductivity , Cu 2 S-based thermoelectric materials are attracting extensive attention. However, they still confront the problem of higher electrical resistivity, which distinctly restricts their thermoelectric application. Herein, we synthesized Ag-incorporated Cu 2-x S micro/nano composites using a hydrothermal method . It was found that the doping of Ag nanoparticles could effectively enhance the electrical transport, while the generated nanopores , caused by the sintering of Ag nanoparticles during the SPS process, reduced the thermal conductivity. As a result, a maximum ZT value of ∼1.5 was obtained at 773 K in the Cu 2-x Ag δ S (δ = 0.5%) micro/nano composites, much higher than that of the pristine Cu 2-x S micro/nano composites. This work provides a new pathway to boosting thermoelectric performance through microstructural engineering.
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Nanomaterials
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2022
·Vol. 12
·期 18
·3191
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IF 5.719
An-Tian Huang,Jun Du,Zhi-Yong Liu,Guang-Cong Zhang,Weinire Abuduwaili,Jia-Yan Yan,Jia-Lei Sun,Ru-Chen Xu,Tao-Tao Liu,Xi-Zhong Shen,Ling Dong,Ji-Min Zhu,Yuhao Li
Hepatocellular carcinoma (HCC) accounts for the predominant form of liver malignancy and presents a leading cause of cancer-related death globally. Sorafenib (SOR), a first-line targeted drug for advanced HCC treatment, has a battery of untoward side effects. Photothermal therapy (PTT) has been utilized as an effective adjuvant in synergy with other approaches. However, little is known about the tumoricidal efficacy of combining SOR with PTT for HCC. Herein, a novel versatile nanoparticle, Cu2−x[email protected]@PEG (CSP), that is based on a photothermal Cu2−xSe core and SOR for simultaneously reinforcing PTT and reducing the adverse effects of SOR was constructed. The synthesized CSP exhibited a remarkably enhanced therapeutic effect upon 808 nm laser irradiation via dampening HCC cell propagation and metastasis and propelling cell apoptosis. The intravenous administration of CSP substantially suppressed tumor growth in a xenograft tumor mouse model. It was noted that the CSP manifested low toxicity and excellent biocompatibility. Together, this work indicates a promising and versatile tool that is based on synergistic PTT and molecular-targeted therapy for HCC management.Keywords:sorafenib;hepatocellular carcinoma;copper(I) selenide;photothermal therapy;synergistic therapy
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Arabian Journal of Chemistry
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2022
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IF 6.212
Jiaxin Li,Chen Zhou,Huan Zhang,Yue Hou,Qingqing Pan,Jing Sun,Xiao Li
In this work, a new highly selective and sensitive fluorescent sensor for detecting Cu 2+ was developed based on rhodamine fluorophore. It displayed strong fluorescence “turn-on” effect upon addition of Cu 2+ , and possessed the function of naked eye recognition. The fluorescence enhancement also enabled the sensor to quantitatively analyze Cu 2+ due to the formation of a stable 1:1 metal–ligand complex in a short time, and the complex possesses relatively good pH stability. In addition, the density functional theory calculations were adopted to investigate the molecular orbitals as well as the spatial structure. Simultaneously, the cell imaging and zebra fish experiments provided a broader application prospect in biological system.
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MACROMOLECULAR CHEMISTRY AND PHYSICS
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2022
·Vol. 223
·期 17
·2200128
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IF 2.996
Yafang Zhang,Guowei Ding,Fengqing Gai,Kun Zhang,Zhiming Gou,Yujing Zuo
In this study, a simple and nontoxic polysiloxane fluorescent probe (P1) is synthesized to detect iron ions, copper ions, and hydrogen peroxide (H 2 O 2 ). Interestingly, both Fe 3+ and Cu 2+ can gradually quench the fluorescence intensity of the probe, and H 2 O 2 can reproduce the probe quenched by Cu 2+ instead of Fe 3+ . The probe shows high selectivity and photostability, and the fluorescence intensity can keep at 95.77% after irradiation at 260 nm for 40 min. In addition, P1 can stably locate lysosome. With excellent property, the probe as lysosome tracker has broad application prospects in detection and biological imaging.
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ACS Sensors
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2022
·
IF 9.618
Leilei Sun,Sisi Shi,Zeming Wu,Yao Huang,Chenhui Ji,Craig A. Grimes,Xinxin Feng,Qingyun Cai
A material system enabling specific NIR-II fluorescence imaging of Gram-positive bacteria is described. The material system is based on the electrostatic binding of Cu2–xSe and vancomycin-modified NaGdF4:Nd,Yb@NaGdF4 downconversion nanoparticles (DCNPs), the fluorescence of which is weak owing to the spectral overlap of Cu2–xSe absorption with the DCNP NIR emission. The presence of Gram-positive bacteria precisely disconnects the bond between vancomycin-modified DCNPs and Cu2–xSe, thus enabling a strong fluorescent signal. In vivo studies show that the material system can be specifically activated at the site of Gram-positive bacterial infection but is essentially nonfluorescent in the area of Gram-negative bacterial infection.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2022
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IF 6.371
Le Luo,Zhenghua Wang
Cu 2−x S nanochains network (NCNW) with tunable diameter in the range of 5–9 nm is prepared by a self-assembly strategy. Control experiments reveal that poly (sodium 4-styrenesulfonate) plays a key role in guiding the assembly of the nanochains. The Cu 2−x S NCNW demonstrates a broad localized surface plasmon resonance (LSPR) band in the near-infrared-Ⅱ region, which matches the optical window of biological tissues. The LSPR band of the Cu 2−x S NCNW red-shifts and intensifies with the increase of diameter. The Cu 2−x S NCNW with an average diameter of 8.7 nm exhibits a high photothermal conversion efficiency of 80.7% under 808 nm laser (0.75 W cm −2 ). Furthermore, the thermal effect stability of the Cu 2−x S NCNW is also good. In vitro experiments demonstrate that all the nanochains possess low cell cytotoxicity. The 8.7 nm Cu 2−x S NCNW own the maximum cellular uptake, and can cause> 90% apoptosis rate of Hela cells under low power density laser (808 nm, 0.75 W cm −2 ), demonstrating its promising application in photothermal therapy.
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CHEMOSPHERE
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2021
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IF 7.086
Caihong Qin,Chaochao Jiang,Mengke Guo,Rongrong Liu,Rui Yu,Jiayu Huang,Dongjie Yan,Shijie Li,Xiaoqing Dang
By-product ozone emission is one of the challenges for applying dielectric barrier discharge (DBD) technology for volatile organic compounds (VOCs) removal. In this study, a DBD reactor followed by a wet scrubber (WS) containing a solution of metal ions (Fe 2+ /Mn 2+ /Cu 2+ ) was used to reuse ozone for further oxidation of typical VOC toluene. Compared with the degradation effect of the DBD reactor alone, DBD coupled WS/iron system not only improved the toluene removal efficiency but also significantly reduced the ozone emission. The ozone removal efficiency reached as high as 98% in the DBD coupled WS/Fe 2+ system. Electron paramagnetic resonance (EPR) tests showed that ozone was converted into radicals such as hydroxyl radicals in Fe 2+ and Cu 2+ solution, which further oxidized toluene in WS/iron. Quenching experiments showed that the contribution for toluene degradation by radicals was up to 75% and 62% in Fe 2+ and Mn 2+ reactor, respectively. This study demonstrates that the DBD coupled WS system has the potential to be an environmentally friendly technology for gaseous VOCs removal.
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DYES AND PIGMENTS
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2021
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IF 4.889
Chunyu Yu,Danyang Zhang,Qi Zhu,Daiyong Chao,Hua Liu,Liang Zhou
In this work, hydroquinone, o -phenylenediamine and terephthalic acid were used as reaction precursors to synthesize carbon dots (h-CDs) by a one-step solvothermal method. Our experimental results demonstrated the as-prepared functionalized h-CDs have not only excellent optical properties but also interestingly chemical and physical properties. The emission peak of the obtained h-CDs shifts gradually towards the red region with increasing water content in organic solvent . This was visually manifest as a change in color. Therefore, the h-CDs can be used as the colorimetric fluorescent probe to detect water content in organic solvents. Moreover, it is also particularly sensitive to Cu 2+ and thus could be used as fluorescent probe to detect Cu 2+ content in water with detection limit of 1.8 × 10 −4 mmol. This investigation provides a new way for the development of carbon dots (CDs) as multifunctional fluorescent probes.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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2023
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IF 5.8
Shen Qiang,Wu Tao,Zhang Guo-Bang,Ma Hao-En,Wang Wei,Pan Guo-Xiang,Zhang Yi-Fan
Heavy metal ions that exist in groundwater and farmland jeopardize the ecological environment and are very difficult to remove because of the complicated actual environment. Raw bentonite–gelatin beads (RB-GT) and magnetic bentonite–gelatin beads (MB-GT) synthesized in this work would be an appropriate tool to solve this problem. Those beads are synthesized by a facile hybrid injection method. Their adsorption behaviors on Cu(II) ions were systematically investigated using the batch adsorption method. The beads were characterized by scan electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared spectra (FTIR), and X-ray photoelectron spectroscopy (XPS). The adsorption isotherm and adsorption kinetic study showed that the Cu 2+ adsorption by MB-GT beads fitted the Langmuir model and the pseudo-second model. The adsorption maximum capacities reached 192.5 mg/g and 236.5 mg/g with Cu concentration of 1000 mg/L for RB-GT and MB-GT beads, respectively. The competitive adsorption with other heavy metal ions (Ni(II), Pd(II) and Cd(II)) were compared. The adsorption of Cu(II) mechanisms is also further discussed. Graphical Abstract
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SEPARATION AND PURIFICATION TECHNOLOGY
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2023
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IF 8.6
Jiayi Wu,Qin Liu,Yan Wang
Thin film composite (TFC) membranes are commonly used for organic solvent nanofiltration (OSN) application. However, these membranes normally suffer from the layer delamination under harsh conditions. Chemically integral crosslinking is a common method to address this problem, but the resultant tightened polymeric chains and denser microstructure will inevitably bring the reduced solvent permeance. In this work, a facile metal integral crosslinking strategy, which has minimal adverse effect on the solvent permeance, was developed to improve the tolerance to the majority of organic solvents as well as enhance the adhesions of upper selective layers and underlying substrates simultaneously for the first time. The as-developed Cu 2+ integrally-crosslinked membranes demonstrated a high permeance for organic solvents and a high rejection towards rose bengal. In comparison to the Cu 2+ partially-crosslinked membranes (with substrate crosslinked only), the integrally-crosslinked ones exhibited superior solvent resistance and OSN performance. This improvement was attributed to the enhanced interactions and a defect-free PA layer. Additionally, the effects of solvent activation, crosslinking solution concentration as well as crosslinking time were also studied. It is believed that metal integral crosslinking strategy will offer a novel approach to develop promising TFC membranes with satisfactory OSN performance for practical applications.
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JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
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2023
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IF 3.6
Jie Yang,Xiao-Jie Wang,Si-Mei Li,Dong-Xue Jiang,Yu-Xin Liu,Yan Huang,Di-Di Dong,Wei Hu,Bo Liu
Nowadays, chemotherapy is a common clinical treatment for cancer, but it still faces many limitations and challenges. Therefore, the combination of chemotherapy and other treatments often enhances the effectiveness of treatments. Herein, an injectable hydrogel of PC10ARGD/Cu2+/DOX based on Cu2+, hydrophilic doxorubicin (DOX), and genetically engineered polypeptide PC10ARGD was prepared. First, Cu2+ was attached to the histidines in the PC10ARGD polypeptide by the coordination reaction to form PC10ARGD/Cu2+ hydrogel, then the PC10ARGD/Cu2+/DOX hydrogel was prepared by encapsulating the DOX into the PC10ARGD/Cu2+ hydrogel. The results of scanning electron microscopy showed that the PC10ARGD/Cu2+/DOX hydrogel displayed loose porous morphology. In vitro, reactive oxygen species production results showed that the PC10ARGD/Cu2+/DOX hydrogel could continuously produce ·OH in the presence of H2O2. In vitro MTT results showed that the PC10ARGD/Cu2+/DOX hydrogel had a good inhibitory effect on cell activity. Flow cytometry further confirmed the antitumor effect of the PC10ARGD/Cu2+/DOX hydrogel. In vivo experiment results showed that the tumor volume of mice treated with the PC10ARGD/Cu2+/DOX hydrogel was significantly inhibited compared with control groups, which was due to the combination of chemodynamic and chemotherapy. The results of body weight and blood analysis of mice showed that the PC10ARGD/Cu2+/DOX hydrogel possessed good biocompatibility.
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CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
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2021
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IF 1.134
Xia-Chu-Qin LI,Tong YANG,Jian WANG,Cheng-Zhi HUANG
In this work, electrospun nanofibers (NFs) with good moisture-resistance were prepared by electrospinning technology, and further assembled with CdTe quantum dots (CdTe QDs). The results of scanning electron microscopy, transmission electron microscopy and confocal fluorescence microscopy showed that the CdTe QDs with strong fluorescence were uniformly assembled on the surface of electrospun NFs after the electrostatic adsorption for 90 min at pH 7.2. Under 365 nm excitation, the CdTe QDs-NFs assembly presented red fluorescence, which could be significantly quenched by copper ion (Cu 2+ ), and the fluorescence quenching degree of CdTe QDs-NFs assembly showed a good linear relationship with Cu 2+ concentration in the range of 0.08–800 μmol/L, and the detection limit was 11.1 nmol/L. This method had advantages of simplicity and high selectivity, and was successfully applied to the visualization and portable detection of Cu 2+ in environmental water samples.
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