INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2017
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IF 3.582
Hang Jia,Xue-Jian Liu,Xin Chen,Xin-Xin Guan,Xiu-Cheng Zheng,Pu Liu
Magnetic chitosan (CS-Fe 3 O 4 ) was synthesized via a co-precipitation method and used as supports to anchor palladium nanoparticles (Pd(0)/CS-Fe 3 O 4 ) by chemical reduction of PdCl 2 with NaBH 4 . The results showed that the nanosized palladium particles were highly dispersed onto CS-Fe 3 O 4 and the resulting Pd(0)/CS-Fe 3 O 4 catalysts exhibited high catalytic activity and good recyclability for the hydrolysis of ammonia borane (NH 3 BH 3 , AB). The turnover frequency (TOF) of the catalysts was as high as 15.0 m o l H 2 · m o l P d − 1 · m i n − 1 at 30 °C and the catalytic activity had not obvious decrease even after eight recycle experiments. The results of kinetic experiments showed that the activation energy of the reaction (E a ) is 35.94 kJ mol −1 . The orders of palladium and AB concentrations in the catalytic reaction were 0.70 and 0.62, respectively.
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Journal of Nano Research
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2017
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IF 0.511
Wan Xin Jia,Dong Tao Lu,Shao Min Shuang,Jun Yang,Chuan Dong
Magnetic chitosan nanoparticles (Fe3O4-CS MNPs) were synthesized by an improved one-pot hydrothermal method and applied for azo dye amido black 10B adsorption. The Fe3O4-CS MNPs were characterized by SEM, TEM, DLS, XRD, FTIR, TGA and VSM. The adsorptive behavior of amido black 10B on Fe3O4-CS MNPs was investigated using the UV-vis specteophotometric technique and the affecting parameters including solution pH, contact time, amido black 10B concentration and Fe3O4-CS MNPs amount were examined. The adsorption process followed the pseudo-second-order kinetic model. The adsorption equilibrium data fitted well with the Freundlich isotherm model with the saturated adsorption capacity of 124.8 mg/g at pH=2.0. The desorption experiment could be carried out using NaOH with the recovery of 91.78%. After five cycles, adsorption efficiency still reached 83.24%. The results showed that Fe3O4-CS MNPs possessed a simple synthesis route and excellent reusability, which have potential application in the adsorption of azo dye in environmental effluents.
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CARBOHYDRATE POLYMERS
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2024
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IF 10.7
Yang Yu,Liang Zhang,Bin Hu,Zhengyue Wang,Qiuping Gu,Wenyi Wang,Chunping Zhu,Shige Wang
Chitosan has been widely used in biomedical fields due to its good antibacterial properties, excellent biocompatibility, and biodegradability. In this study, a pH-responsive and self-healing hydrogel was synthesized from 3-carboxyphenylboronic acid grafted with chitosan (CS-BA) and polyvinyl alcohol (PVA). The dynamic boronic ester bonds and intermolecular hydrogen bonds are responsible for the hydrogel formation. By changing the mass ratio of CS-BA and PVA, the tensile stress and compressive stress of hydrogel can controlled in the range of 0.61 kPa - 0.74 kPa and 295.28 kPa - 1108.1 kPa, respectively. After doping with tannic acid (TA)/iron nanocomplex (TAFe), the hydrogel successful killed tumor cells through the near infrared laser-induced photothermal conversion and the TAFe-triggered reactive oxygen species generation. Moreover, the photothermal conversion of the hydrogel and the antibacterial effect of CS and TA give the hydrogel a good antibacterial effect. The CS-BA/PVA/TAFe hydrogel exhibit good in vivo and in vitro anti-tumor recurrence and antibacterial ability, and therefore has the potential to be used as a powerful tool for the prevention of local tumor recurrence and bacterial infection after surgery.
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Biomaterials Advances
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2024
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IF 5.5
Kunpeng Jia,Changpeng Zuo,Yan Xu,Wenfu Ma,Lingtao Wang,Yan Ji,Jie Chen,Qiuyang Zhang,Changjiang Pan,Tingting Liu
Titanium and its alloys are widely used as orthopedic implants owing to their good mechanical properties and excellent corrosion resistance. However, the insufficient osteogenic activity and antibacterial properties hinder their clinical applications. To address these issues, TiO 2 nanotube arrays (TNT) were first fabricated on the TA2 alloy surface via an anodizing technique, and strontium ions (Sr 2+ ) were then loaded by hydrothermal reaction (TNT + Sr) and annealing treatment (TNT + A). Subsequently, the polydopamine layer (TNT + PDA) was constructed to immobilize the carboxymethyl chitosan and alendronate sodium (TNT + CA) mixture. The prepared coatings were thoroughly characterized by scanning electron microscopy (SEM), energy dispersive spectrometer (EDS), X-ray photoelectron spectrometer (XPS), attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR), X-ray diffractometer (XRD), and water contact angle measurement. The results confirmed that Sr 2+ ions, polydopamine, and carboxymethyl chitosan/alendronate sodium were successfully immobilized on the nanotubes. The coating of TNT + CA significantly enhanced the hydrophilicity, and effectively delayed the release of Sr 2+ and alendronate. The TNT + CA coating significantly promoted osteoblast adhesion and proliferation, and up-regulated the expressions of alkaline phosphatase (ALP), osteocalcin (OCN), and osteoblast-specific transcription factor (RUNX2). TNT + CA was able to rapidly induce in situ hydroxyapatite deposition from the simulated body fluid (SBF). Moreover, TNT + CA coating showed inhibition against Escherichia coli and Staphylococcus aureus (especially against Escherichia coli ). The prepared TNT + CA coating provides a novel strategy for enhancing bone affinity, improving osteoblast behaviors, and antibacterial properties of titanium-based biomaterials.
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ACS Biomaterials Science & Engineering
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2024
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IF 5.4
Maoxue Li,Guoping Cheng,Shimeng Xiao,Bo Jiang,Shujuan Guo,Yi Ding
Commercial mammalian collagen-based membranes used for guided tissue regeneration (GTR) in periodontal defect repair still face significant challenges, including ethical concerns, cost-effectiveness, and limited capacity for periodontal bone regeneration. Herein, an enhanced biomimetic mineralized hydroxyapatite (HAp)–fish-scale collagen (FCOL)/chitosan (CS) nanofibrous membrane was developed. Specifically, eco-friendly and biocompatible collagen extracted from grass carp fish scales was co-electrospun with CS to produce a biomimetic extracellular matrix membrane. An enhanced biomimetic mineralized HAp coating provided abundant active calcium and phosphate sites, which promoted cell osteogenic differentiation, and showed greater in vivo absorption. In vitro experiments demonstrated that the HAp-FCOL/CS membranes exhibited desirable properties with no cytotoxicity, provided a mimetic microenvironment for stem cell recruitment, and induced periodontal ligament cell osteogenic differentiation. In rat periodontal defects, HAp-FCOL/CS membranes significantly promoted new periodontal bone formation and regeneration. The results of this study indicate that low-cost, eco-friendly, and biomimetic HAp-FCOL/CS membranes could be promising alternatives to GTR membranes for periodontal regeneration in the clinic.
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CARBOHYDRATE POLYMERS
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2024
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IF 10.7
Jingxi Wang,Kun Li,Yunxue Jia,Tianran Song,Junwei Xu,Xuemei Sun,Meili Liu,Ping Li,Yubo Fan
The single structure, poor mechanical properties, and low biological activity of wound dressings usually lead to unsatisfactory treatment effects. Gelatin and chitosan possess excellent biofunction, but they lack sufficient mechanical support. Magnetic biomaterials and magnetic fields have shown surprising tissue repair potential. Herein, inspired by the skin structure and considering the bioactive composition, a superparamagnetic asymmetric membrane was constructed by incorporating gelatin, chitosan, and magnetic Fe 3 O 4 nanoparticles. The proposed membrane exhibited a high degree of asymmetry, achieving functional diversification. The surface of the top layer was highly hydrophobic as an isolation barrier. The top layer consisted of dense fibrous chitosan with high mechanical strength and excellent antibacterial properties. The bottom layer was composed of gelatin sponge with distributed magnetic nanoparticles, possessing high porosity and swelling ratio to effectively absorb tissue exudates and support cell growth. Furthermore, the membrane demonstrated significant promotion of human dermal fibroblast proliferation under a static magnetic field. In a full-thickness mouse skin wound model, the membrane effectively accelerated wound healing with reduced wound area, abundant collagen disposition, and enhanced vascularization. Therefore, the superparamagnetic gelatin/chitosan asymmetric membrane with a biomimetic structure and function exhibits remarkable superiority and provides a promising approach to effective wound healing.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Lili Zhang,Yuxuan Xu,Tengyu Feng,Yu Zhang,Jiajun Sun,Xiaodong Wang,Chengying Bai,Xiaohong Zhang,Jun Shen
There is a growing demand for the development of epoxy resin modified with biomaterials, aiming to achieve high toughness. Herein, chitosan crosslinked epoxy resin (CE) was synthesized by diisocyanate as a bridge. With 4,4′-diamino-diphenylmethane (DDM) as the curing agent, thanks to the unique cross-linking structure of the CE resin and the presence of carbamate groups, the cured CE/DDM exhibited superior properties compared to commercially available epoxy resin (E51). The tensile strength of the cured CE-3/DDM reached 90.17 MPa, the elongation at break was 11.2 %, and the critical stress intensity factor (K IC ) measured 1.78 MPa m 1/2 . These values were 21.4 %, 151.6 %, and 81.6 % higher than those of the cured E51/DDM, respectively. It is worth noting that the addition of biomass material chitosan did not reduce the thermal stability of the resin. Additionally, the CE coatings on the metal substrate exhibited exceptional corrosion resistance , as evidenced by higher impedance values in electrochemical impedance spectroscopy (EIS) and polarization voltages in the Tafel curve compared to those of the E51 coating. This study opens up a novel approach to modifying epoxy resin with biomass materials with high toughness and corrosion resistance, without sacrificing other performance.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Hanchen Wang,Lijia Jia,Biao Huang,Qi-Lin Lu
The construction of N, P co-doped hierarchically porous carbons (NPHPC) by a facile and green approach is crucial for high-performance energy storage but still an enormous challenge. Herein, an environment-friendly “ in-situ co-doping, self-regulation-activation” strategy is presented to one-pot synthesize NPHPC using a phytic acid-induced polyethyleneimine/chitosan gel (PEI-PA-CS) as single precursor. NPHPC displayed a specific surface area of up to 1494 m 2 g −1 , high specific capacitance of 449 F g −1 at 1 A g −1 , outstanding rate capability and cycling durability in a wide temperature range (−20 to 60 °C). NPHPC and PEI-PA-CS electrolyte assembled symmetric quasi-solid-state flexible supercapacitor presents superb energy outputs of 27.06 Wh kg −1 at power density of 225 W kg −1 . For capacitive deionization (CDI), NPHPC also exhibit an excellent salt adsorption capacity of 16.54 mg g −1 in 500 mg L −1 NaCl solution at a voltage of 1.4 V, and regeneration performance. This study provides a valuable reference for the rational design and synthesis of novel biomass-derived energy-storage materials by integrating phytic acid induced heteroatom doping and pore engineering.
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JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
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2025
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IF 2.8
Zhuo Mi,Wenkang Zhang,Han Wang,Xingyi Qi,Shuo Wang,Jiayi Song,Ping Su,Yi Yang
Glycopeptides are an important biomarker, which play a crucial role in various biological processes. Due to their low abundance and the presence of interfering macromolecular proteins, enrichment of glycopeptides is necessary before testing. However, most materials for enriching glycopeptides have high site resistance, relatively low surface area, and limited recognition sites. Herein, a highly hydrophilic two-dimensional (2-D) covalent organic framework (NUS-10) loaded with chitosan (CS) (denoted as NUS-10@CS) had been synthesized. After enrichment with NUS-10@CS, a total of 34 glycopeptides from horseradish peroxidase (HRP) tryptic digests were detected, demonstrating a high enrichment efficiency for glycopeptides from model glycoprotein digestion. Meanwhile, the material exhibited ultra-high adsorption capacity (1 fmol/μL HRP), excellent selectivity (HRP tryptic digest/bovine serum albumin (BSA) tryptic digest = 1:2000), macromolecular protein anti-interference ability (HRP tryptic digest/BSA = 1:2000) and good binding capacity (200 mg/g). Additionally, 712 glycopeptides corresponding to 200 glycoproteins were identified from 3 µL human serum. NUS-10@CS was promising for glycopeptide analysis, helping to identify potential disease biomarkers more efficiently, and leading to easier and more accurate diagnosis of diseases, which was essential for early intervention and treatment.
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JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
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2024
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IF 3.3
Ming Cheng,Ye Tao,Chunwei Wang,Ao Li
BACKGROUND Phytosterols (PS) have various beneficial effects on human health, especially the property of reducing blood cholesterol. However, the low solubility and bioaccessibility of PS have greatly limited their application in functional food ingredients. RESULTS To improve the bioaccessibility and stability of PS, chitosan-coated PS nanoparticles (CS-PNP) were successfully prepared by self-assembly. The properties of CS-PNP, including size, zeta potential, encapsulation efficiency (EE) and loading amount (LA) were characterised. The optimisation of CS concentration (0.4 mg mL −1 ) and pH (3.5) resulted in the formation of CS-PNP with an EE of over 90% and a particle size of 187.7 nm. Due to the special properties of CS chitosan, the interaction between CS and soybean protein isolate (SPI)/lecithin (SL) led to the formation of a soluble complex. CS-PNP exhibited good stability to temperature variations but was more sensitive to salt ions. During in vitro digestion, CS efficiently maintained the stability of nanoparticles against the hydrolysis of SPI by pepsin under acidic conditions. However, these nanoparticles tended to aggregate in a neutral intestinal environment. After 3 h of in vitro digestion, the bioaccessibility of PS increased from 18.2% of free PS to 63.5% of CS-PNP. CONCLUSION Overall, these results highlight the potential of chitosan-coated nanoparticles as effective carriers for the oral administration of PS. This multilayer construction may serve as a promising for applications in food products as delivery vehicles for nutraceuticals. © 2024 Society of Chemical Industry.
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JOURNAL OF POWER SOURCES
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2024
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IF 8.1
Yu Zhang,Yaolong Zhang,Ruxangul Jamal,Shuyue Xie,Abdukeyum Abdurexit,Tursun Abdiryim,Nana Fan,Nuramina Abdukirim,Zhigang Wang
While researching anode catalysts in DMFC that are based on platinum, achieving smaller particle diameters and homogeneous dispersion of Pt nanoparticles (NPs) is crucial for enhancing catalyst activity. In this research, chitosan−based nitrogen−doped carbon aerogel (CA) was modified with poly(3,4−ethylenedioxythiophene) (PProDOT) through in situ polymerization to obtain PProDOT/CA as a catalyst carrier. The unique three−dimensional mesh structure of CA provides a larger active area for the catalyst, while the modification with PProDOT not only introduces more reactive sites, but also enhances the dispersion of Pt NPs and reduces their particle size. Methanol oxidation is improved by the Schottky connections that develop at the interface of Pt nanoparticles (NPs). The Pt/PProDOT/CA catalyst shown remarkable electrocatalytic activity during methanol oxidation, as demonstrated by the test findings,(electrochemically active surface area, ECSA value is 71.20 m 2 g −1 and mass activity, MA value is 997.40 mA mg −1 Pt ). Additionally, the catalyst demonstrated good long−term working stability and resistance to CO toxicity. Furthermore, methanol molecules exhibited lower activation energy on the surface of this catalyst, indicating that methanol is more easily oxidized upon adsorption.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Xinyuan Zhang,Yongkang Lai,Liang Zhang,Zheng Chen,Jiulong Zhao,Shige Wang,Zhaoshen Li
Helicobacter pylori ( H. pylori ) is one of the major causes of gastrointestinal diseases, including gastric cancer. However, the acidic environment of the stomach and H. pylori resistance severely impair the antimicrobial efficacy of oral drugs. Here, a biocompatible chitosan-modified molybdenum selenide (MoSe 2 @CS) was designed for the simultaneous photothermal treatment of H. pylori infection and gastric cancer. MoSe 2 @CS showed a photothermal conversion efficiency was as high as 45.7 %. In the H. pylori -infected mice model, MoSe 2 @CS displayed a high bacteriostasis ratio of 99.9 % upon near-infrared irradiation. The antimicrobial functionality was also proved by transcriptomic sequencing study, which showed that MoSe 2 @CS combined with NIR laser irradiation modulated the gene expression of a variety of H. pylori bioprocesses, including cell proliferation and inflammation-related pathways. Further gut flora analysis results indicated that MoSe 2 @CS mediated PTT of H. pylori did not affect the homeostasis of gut flora, which highlights its advantages over traditional antibiotic therapy. In addition, MoSe 2 @CS exhibited a good photothermal ablation effect and significantly inhibited gastric tumor growth in vitro and in vivo . The comprehensive application of MoSe 2 @CS in the PTT of H. pylori infection and gastric cancer provides a new avenue for the clinical treatment of H. pylori infection and related diseases.
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