MOLECULES
·
2025
·Vol. 30
·期 18
·3704
·
IF 4.6
Jing Zhou,Qiqi Zhang,Mengying Wang,Zongmu Xiao,Yixin Zhang
The design and development of low-cost and efficient nonhomogeneous catalysts for silicon hydrogen addition is a hot research topic. This study reports the synthesis of a novel solid catalyst, PtCu-NVF-HBNC, derived from hazelnut shell biomass waste. The catalyst was prepared through carbonisation, nitrogen-doped activation, functionalisation with N-vinylformamide (NVF), and subsequent bimetallic Pt–Cu loading. It features a divalent platinum–vinylamine complex as the active centre. The introduction of Cu as a promoter induces competitive coordination with the Pt(II)–vinylamine complex, leading to electron density redistribution on the vinylamine ligand and a significant enhancement in Pt(II) coordination bond strength. This electronic modulation results in markedly improved activity and regioselectivity in the hydrosilylation of alkenes with tertiary silanes. The optimised catalyst, Pt1.6Cu-NVF-HBNC, demonstrated high performance in the hydrosilylation of linear alkenes, including 1-hexene, 1-octene, and 1-octadecene with triethoxysilane, indicating broad substrate adaptability.
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Nano-Micro Letters
·
2023
·Vol. 15
·期 1
·1-13
·
IF 26.6
Gao Manyi,Tian Fenyang,Zhang Xin,Chen Zhaoyu,Yang Weiwei,Yu Yongsheng
A hybrid co-catalysts system comprising Au nanoparticles (NPs) and PtSAs with different functions was constructed on the polymeric carbon nitride (PCN) surface by double-solvent method.
For the dual co-catalysts, the Au NPs absorb relatively long-wavelength light to produce plasmonic hot-electrons, and the adjacent Pt single atoms (PtSAs) can trap the plasmonic hot-electrons effectively for H 2 evolution.
The PtSAs–Au 2.5 /PCN exhibits excellent broad-spectrum photocatalytic H 2 evolution activity with the H 2 evolution rate of 8.8 mmol g − 1 h − 1 at 420 nm and 264 μmol g − 1 h − 1 at 550 nm, respectively.
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Energy & Environmental Materials
·
2020
·Vol. 4
·期 1
·126-133
·
IF 0
Xiantao Meng,Xiang Deng,Liusheng Zhou,Bin Hu,Wenyi Tan,Wei Zhou,Meilin Liu,Zongping Shao
One of the critical challenges that limit broad commercialization of proton exchange membrane fuel cells (PEMFC) is to reduce the usage of Pt while maintaining high power output and sufficient durability. Herein, a novel bi-functional layer consisting of vertically aligned carbon nanotubes (VACNTs) and nanoparticles of Pt-Co catalysts (Pt-Co/VACNTs) is reported for high-performance PEMFCs. Readily prepared by a two-step process, the Pt-Co/VACNTs layer with a hydrophilic catalyst-loaded side and a hydrophobic gas diffusion side enables a PTFE-free electrode structure with fully exposed catalyst active sites and superior gas–water diffusion capability. When tested in a PEMFC, the bi-functional Pt-Co/VACNTs layer with ultralow Pt loading (~65 μg cathode cm −2 ) demonstrates a power density of 19.5 kW g Pt cathode −1 at 0.6 V, more than seven times that of a cell with commercial Pt/C catalyst (2.7 kW g Pt cathode −1 at 0.6 V) at a loading of 400 μg cathode cm −2 tested under similar conditions. This remarkable design of VACNTs-based catalyst with dual functionalities enables much lower Pt loading, faster mass transport, and higher electrochemical performance and stability. Further, the preparation procedure can be easily scaled up for low-cost fabrication and commercialization.
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International Journal of Electrochemical Science
·
2023
·Vol. 10
·期 3
·1953-1965
·
IF 1.5
Zhong Wang,Zhenhua Yan,Min Wang,Jinsheng Zhao
The high cost and insufficient catalytic activity of carbon-supported Pt nanoparticle catalysts are two main problems in the commercial deployment of microbial fuel cell (MFC). In an effort to address these barriers, three carbon-supported Pt-Ni alloy electrocatalysts with varying Pt:Ni atom ratios (Pt 3 -Ni/C, Pt 2 -Ni/C, Pt-Ni/C) were prepared by simple NaBH 4 reduction in glycerol at room temperature. All of the prepared Pt-Ni alloy nanoparticles (NPs) are highly dispersed on a carbon support and show a single-phase face-centered cubic structure with a particle size of 2.4-3.0 nm. The electrocatalytic performances of the synthesized Pt-Ni alloy catalysts were compared with that of commercial Pt/C by cyclic voltammetry and linear sweep voltammetry; among these NPs, the Pt 2 -Ni/C catalyst exhibits the highest activity for oxygen reduction reaction (ORR) in 0.1M HClO 4 . As the cathode catalyst, the maximum power density produced from MFC with Pt 2 -Ni/C (1724 mW m -2 ) was 22% higher than that with commercial Pt/C (1413 mW m -2 ).
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yutao Zhu,Jia Qiu,Yulou Qiu,Xuping Shentu,Zihong Ye,Xiaoping Yu
A multifunctional core-shell Fe 3 O 4 @Ru@Pt nanozyme was synthesized. • A cascade multimodal LFIA for sensitive and reliable detection of β-CG was developed. • A 151-fold sensitivity improvement was achieved through cascade amplification. • Four detection modes provided flexible readout and cross-validation. Traditional lateral flow immunoassays (LFIAs) suffer from limited sensitivity and insufficient reliability, which restrict their practical application. To address these challenges, we synthesized a multifunctional core-shell Fe 3 O 4 @Ru@Pt nanozyme with integrated magnetic, optical, catalytic, and photothermal properties. This nanozyme enables a three-step cascade that enhances sensitivity through sequential magnetic enrichment, catalytic amplification, and photothermal amplification. In addition, four detection modes (direct colorimetric, magnetic-enriched colorimetric, catalytic colorimetric, and photothermal) provide flexible readout and cross-validation to improve reliability. Using a specific phage-displayed nanobody as the recognition element, we developed a Fe 3 O 4 @Ru@Pt-based cascade multimodal LFIA for β-conglycinin detection. The photothermal mode achieved a limit of detection as low as 2.02 pg mL −1 , representing a 151-fold improvement over the direct colorimetric mode. The assay also exhibited excellent specificity and satisfactory accuracy in spiked real samples, with recoveries of 83.21%–114.72%. This multifunctional nanozyme-mediated cascade multimodal platform substantially improves both sensitivity and reliability, offering a promising and practical tool for point-of-care testing applications.
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International Journal of Minerals Metallurgy and Materials
·
2026
·Vol. 33
·期 6
·1870-1885
·
IF 8.8
He Baili,Kou Jue,Sun Chunbao,Li Yue,Li Xiaolin,Temirov Uktam,Chang Ziyong
The development of effective adsorbents is crucial for the sustainable recovery of noble metals from secondary resources. In this study, MIL-101(Cr)-Tu, a Cr-based metal–organic framework (MOF) modified with thiourea, was successfully prepared by double-phase encapsulation followed by post-synthetic modification. At 298 K, the largest adsorption capacities of Au(III), Pd(II), and Pt(IV) by MIL-101(Cr)-Tu were (1230.83 ± 8.72), (330.41 ± 7.29), and (315.58 ± 13.67) mg·g −1 , respectively. The uptakes of Au(III), Pd(II), and Pt(IV) increased with temperature. The adsorption data fit well to both the Langmuir and pseudo-second-order kinetic models, indicating that the adsorption process conformed to monolayer adsorption and chemisorption. Mechanistic analysis revealed that the amino and thiourea groups facilitated the adsorption of noble metals through coordination and electrostatic attraction. Notably, Au(III), Pd(II), and Pt(IV) interacted strongly with the thiourea groups owing to their “soft–soft” interactions. Moreover, Au(III) was reduced to Au(I) and Au(0), Pt(IV) was reduced to Pt(II), and the amino groups were oxidized to NO 2 . The adsorption of Pd(II) did not involve redox reactions. Additionally, MIL-101(Cr)-Tu exhibited strong selectivity for noble metals and excellent reusability, demonstrating its great potential for the extraction of noble metals from secondary resources.
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BMEMat
·
2026
·
IF 17.2
Kairui Liu,Bo Zhang,Yue Wan,Zhiru Yang,Abdusami Abdurahman,Mengxin He,Shengtao Hu,Yi Zhang,Xiaoke Li,Jin Chang,Jun Kang,Liren Liu,Wanghua Liu,Shao Li
Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer-related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt-TiO 2 nanoparticles for the co-delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic therapy (SDT). Phl@PT demonstrated remarkable efficacy in inducing mitochondrial membrane potential collapse and cristae damage in vitro. Transcriptomic sequencing analysis revealed that Phl@PT treatment led to the downregulation of key genes: CLDN6 , involved in the cell adhesion molecules pathway, and BCKDHB and SUCLG2 , associated with propanoate metabolism. Through a comprehensive target fishing strategy combined with Bio-Layer Interferometry analysis, we identified DDX5, a DEAD-box RNA helicase, as a novel target protein of Phlorezin, which plays a crucial role in tumor progression and prognosis. In vivo studies demonstrated that US-activated Phl@PT not only effectively inhibited HCC growth in murine models but also activated CD8 + /CD4 + T cells, promoted dendritic cell maturation, and enhanced the expression of key immune cytokines including TNF-α, IL-12, and IFN-γ, thereby establishing a robust immunotherapeutic response. Collectively, our findings demonstrate that the Pt-TiO 2 mesoporous nanoagent co-delivering phlorezin represents a promising therapeutic platform for HCC treatment through synergistic sonodynamic-chemo-immunotherapy.
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RSC Advances
·
2026
·Vol. 16
·期 26
·23314-23325
·
IF 6.1
Xiaodong Zhou,Fengqin Guo,Ziqiang Han,Jiajun Zhang,Yan Cao,Huiquan Li,Guozhu Chen,Liguo Wang
The selective hydrogenolysis of furfuryl alcohol (FFA) to 1,2-pentanediol (1,2-PeD) represents a promising route for biomass valorization, yet it remains challenging due to the competing over-hydrogenation of the furan ring and the recalcitrant C5–O bond cleavage. Herein, we report a highly efficient bimetallic Pt–Y catalyst supported on a MgO–AlO(OH) mixed oxide (MAO) that enables the selective hydrogenolysis of FFA to 1,2-PeD under remarkably mild conditions (140 °C, 0.8 MPa H2). Structural characterizations (AC-HAADF-STEM, XPS) confirm the formation of Pt–Y mixed clusters, which induce electron transfer from Pt to Y. This electronic modulation, combined with the tailored basicity of the MAO support, effectively suppresses the over-hydrogenation pathway while promoting the activation of the target C–O bond. In situ Fourier transform infrared spectroscopy shows that after the introduction of Y, FFA adsorbs on the catalyst surface in a vertical adsorption configuration through its O–H and C–O–C bonds, promoting the selective ring-opening. Consequently, the optimized 0.75Pt0.45Y/MAO catalyst achieves complete FFA conversion with an exceptional 1,2-PeD selectivity of 80.3% (110 mol 1,2-PeD·mol Pt per h), significantly outperforming its monometallic counterparts. Furthermore, the catalyst demonstrates outstanding stability in a continuous-flow reactor for over 200 hours without obvious deactivation. This work provides a strategy for designing synergistic bimetallic catalysts for the sustainable production of 1,2-PeD under mild conditions.
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ENERGY & FUELS
·
2026
·
IF 6
Musitafa Aierken,Ruiming Hu,Yu Tang,Xinyu Zhu,Shaorou Ke,Shujie Yang,Yangai Liu,Zhaohui Huang,Ruiyu Mi,Xin Min,Hao Liu,Minghao Fang
In response to the urgent demand for highly efficient and stable electrocatalysts for the hydrogen evolution reaction (HER) in sustainable energy applications, this study developed a class of high-performance RE–Pt@CN catalysts based on the synergistic effect of rare-earth doping and nitrogen-doped carbon supports. Using 2,2′-bipyridine-5,5′-dicarboxylic acid (DPDC) as a bifunctional ligand, a series of binary catalysts, including Sm–Pt@CN and various RE–Pt systems (RE = Sm, Ce, Gd, Pr, Er, Eu, and Yb), were successfully constructed on nitrogen-doped carbon nanotubes via a hydrothermal-carbonization reduction method. These catalysts exhibit a uniform structure and excellent stability. The Sm–Pt@CN catalyst prepared under optimal conditions (heat treatment at 800 °C, n (Pt):n (Sm):n (DPDC) = 1:1:3) shows uniformly dispersed nanoparticles (approximately 3.7 nm) and outstanding HER activity and stability in 0.5 M H2SO4 electrolyte: it requires an overpotential of only 88 mV to achieve a current density of 100 mA·cm–2, exhibits a Tafel slope of 22.96 mV·dec–1, and delivers a mass activity of 2.30 A·mg–1 at an overpotential of 100 mV, significantly outperforming commercial Pt/C (η100 = 99.8 mV, 26.68 mV·dec–1). The doping of Sm effectively enhances the metal–support interaction between platinum and the carbon carrier, inhibiting nanoparticle growth and aggregation, thereby endowing the catalyst with superior electrochemical stability. The synthesis strategy demonstrates good universality, as other rare-earth-doped platinum-based catalysts (e.g., Ce, Gd, Pr, Er, Eu, and Yb) also exhibit excellent HER performance. This work provides a new material platform and synthetic pathway for the development of highly efficient, stable, and low-platinum-loading electrocatalysts for water electrolysis.
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JOURNAL OF INORGANIC BIOCHEMISTRY
·
2025
·
IF 3.2
Hai-Qun Zhang,Nan-Feng Chen,Hui-Chao Lin,Muhammad Iqbal Choudhary,Hong Liang,Zhen-Feng Chen
Six Pt(II) complexes bearing di(pyridin-2-yl)methanone hydrazone derivative ligands ( Pt1 − Pt6 ) were synthesized and characterized. These complexes exhibited promising antiproliferative activity against multiple cancer cell lines, with low cytotoxicity toward normal human cells. Among them, Pt4 and Pt6 demonstrated the strongest inhibition of A2780 cell proliferation. Mechanistic studies revealed that Pt4 and Pt6 induce apoptosis via mitochondrial dysfunction, accumulation of intracellular Ca 2+ and reactive oxygen species, and activation of caspase-3/9. Importantly, Pt4 , the most potent agent against A2780 cells, displayed superior antitumor efficacy compared to cisplatin in an A2780 xenograft model, with no significant systemic toxicity.
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ACS Nano
·
2025
·
IF 16
Xiaohui Zhan,Yujia Jiang,Zhiyu Li,Xiaoqin Hu,Fang Lan,Binwu Ying,Yao Wu
The screening and monitoring of microRNAs as cancer molecular biomarkers is clinically significant, but traditional methods lack sufficient sensitivity, accuracy, and convenience. The CRISPR-colorimetric lateral flow assay (CLFA) integration offers a promising and efficient solution; however, cumbersome preamplification and poor quantification hinder clinical adoption. In this study, we developed a one-step isothermal CRISPR-Cas cascaded sensing system that is preamplification-free. At its core is a designed and selected split DNA tetrahedron activator, employing spatiotemporal-hierarchy mechanisms to precisely bidirectionally drive the kinetics of two Cas enzymes, accelerating the activation of Cas13a while delaying the initiation of Cas12a, to achieve optimal balance. This system enables ultrasensitive, single-step, single-tube, and rapid detection of a cervical cancer relative biomarker, microRNA-21, achieving a limit of detection of 38 aM with a broad linear range. The CRISPR system is further integrated with CLFA enhanced by ultrathin platinum-protected gold nanolabels (Au@Pt, also named Au@s-Pt), along with a smartphone equipped with dual convolutional neural network models (YOLO v5 and MobileNet v3), enabling more precise, rapid quantification of target miRNA. Using this integrated platform, miRNA-21 levels in cervical cancer and precancerous samples can be accurately quantified with approximately 30 min at low cost and without the need for large, sophisticated instruments, with results showing good concordance with quantitative real-time polymerase chain reaction. This platform provides an efficient, highly sensitive, user-friendly, and quantifiable point-of-care testing solution.
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FOOD CHEMISTRY
·
2026
·
IF 9.8
Jia-Qi Lyu,Jiang-Tao Xu,Hui-Ting Hu,Zhencheng Chen,Guo-Cheng Han,Xiao-Zhen Feng,Heinz-Bernhard Kraatz
An electrochemical detection method was proposed for the detection of Melatonin (MT) based on the synergistic signal amplification of L-Cys and core-shell Cu@Pt bimetallic nanoparticles (Cu@PtNPs). The successful fabrication of the PL-Cys/Cu@PtNPs/GCE was confirmed by characterization techniques including SEM, XRD, and TEM. The method exhibited excellent analytical performance, with a low detection limit of 0.03 μmol/L and a wide linear range across two concentration intervals: 0.1–100.0 μmol/L and 100.0–900.0 μmol/L. The method's practical applicability was successfully validated in human serum and various food samples, achieving satisfactory recovery rates of 98.73 %–99.67 % and 99.49 %–108.57 %, respectively, with relative standard deviations below 6.85 %. The novelty of this work lies in the synergistic amplification effect of the Cu@PtNPs and L-Cys and the application of density functional theory (DFT) calculations to elucidate the MT electrooxidation mechanism, confirming a 2-electron, 1-proton transfer process.
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