DALTON TRANSACTIONS
·
2020
·Vol. 49
·期 8
·2437-2443
·
IF 4.174
Chun-Xin Jin,Yu Wang,Qiu-Shan Gao,Dan-Yang Yao,Si-Hong Wang,Donghao Li,Hai-Bo Shang
Exploring new zeolitic imidazolate frameworks (ZIFs) with specific topologies and pore structures is important for extending applications and improving performances. In this work, a new farfalle-shaped ZIF with an ordered hierarchical structure (named ZIF-F) was easily built with zinc acetate and 2-methylimidazole (MeIm) in an aqueous system at room temperature. The synthesis mechanism of ZIF-F is a dual-induction interaction of a solvent and zinc source based on the synthesis protocol of ZIF-8. The prepared ZIF-F is a 3–5 μm dispersible particle constructed from numerous nanoplates with the same building units as ZIF-8. ZIF-F has a rich 4 nm inter-particle spacing with a 0.1074 cm3 g−1 total pore volume and exhibits high thermo- and solvent stability. It is worth noting that crystal transformation could occur from ZIF-F to ZIF-8 in methanol via the dissolution-recrystallization route. Regarding the adsorption of Congo red (CR), ZIF-F exhibits better adsorption capacity (182.82 mg g−1) than ZIF-8 (149.25 mg g−1) with 6 times higher adsorption rate than that of ZIF-8 because of the positive effect of its larger pore size and hierarchical structure.
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Nanoscale Advances
·
2023
·
IF 4.7
Guo-Ying Chen,Mao-Ling Luo,Li Chen,Tong-Qing Chai,Jia-Li Wang,Ling-Xiao Chen,Feng-Qing Yang
The combined application of nanozymes and natural enzymes has received widespread attention in recent years. In this work, a simple and efficient method was used to synthesize a composite material of CuO nanoparticles modified zeolitic imidazolate framework-8 (CuO NPs@ZIF-8) with multiple enzyme activities (glucose oxidase-like and hydrolase-like activities) to detect the activity of natural enzymes through fluorescence and colorimetric (UV-Vis) dual-mode detections. The hydrolase- and oxidase-like activities of CuO NPs@ZIF-8 show an acceptable affinity with L-ascorbic acid 2-phosphate trisodium (AAP) and o-phenylenediamine (OPD). Using the developed sensor, highly sensitive detection of natural enzymes glucose oxidase (GOX) and alkaline phosphatase (ALP) was achieved through both fluorescent and colorimetric analysis with a wide linear range (fluorescence for GOX: 0.86-1.23×105 mU/mL, UV-Vis for GOX: 0.081-1.62×105 mU/mL; fluorescence for ALP: 0.042-1.20×104 mU/mL, UV-Vis for ALP: 0.0046-1.23×104 mU/mL) and low LOQs (fluorescence for GOX: 0.86 mU/mL, UV-Vis for GOX: 0.081 mU/mL; fluorescence for ALP: 0.042 mU/mL, UV-Vis for ALP: 0.0046 mU/mL). Compared to the other fluorescent and colorimetric sensors, this sensor has better catalytic activity due to the addition of GOX and ALP, which can amplify the detection signal and improve the sensitivity. This is the first time that composite material CuO NPs@ZIF-8 with "tandem enzyme" activity was synthesized and applied in the detection of enzyme activity. Additionally, the proposed fluorescent and UV-Vis platforms exhibit the capability to detect GOX and ALP in serum samples with satisfactory recovery, indicating potential application prospects in biochemical analysis.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 26
·68691-68700
·
IF 5.8
Liu Yuhao,Wang Jieqi,Wang Xuyi,Chen Jiayue,Zhang Beibo,Chen Liping,Zheng Dan,Cheng Ming
It is a great challenge to develop photocatalysts for the degradation of organic pollutants in the aqueous environment, especially those with excellent catalytic performance under visible light conditions. In this work, using graphene oxide (GO) as an electron shuttle agent and carrier, a hybrid of ZIF-8/NH 2 -MIL-125(Ti) and GO (ZIF-8/NH 2 -MIL-125(Ti)/GO) was prepared by a simple two-step solvothermal method. The morphology, structure, and combination of the synthesized catalysts were studied. The results showed that graphene oxide and ZIF-8 formed an in situ load on NH 2 -MIL-125(Ti). The construction of hybrid materials significantly improved the catalytic activity of NH 2 -MIL-125(Ti) in the visible light range. The degradation activity of the synthesized catalyst was further tested with reactive red dye. The results showed that the catalyst exhibited excellent catalytic removal efficiency for active red, with a degradation rate of 99.8% within 2 h. The prepared hybrid materials have good application prospects in the field of organic pollutant treatment in water. Graphical Abstract
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SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Wenhai Wang,Jiaxuan Li,Bin Hong,Yi Ma,Fei Chen,Keren Kang,Jufang Wang
High levels of Cu (II) in the human body can cause kidney dysfunction, liver cirrhosis, and many neurological diseases, such as Wilson’s disease (WD). Therefore, rapid and efficient detection of Cu (II) in urine is highly essential. First, by a simple multiple seeded growth method, the gold nanoclusters (Au NCs) embedded metal-organic framework (ZIF-8) is decorated on cellulose paper to generate a fluorescent Au NCs@ZIF-8 paper. Then the Au NCs@ZIF-8 paper is loaded on the fluidic cartridge integrated with the syringe for ultra-sensitive urine copper detection. The fluorescence paper is intercalated in a reusable fluidic cartridge and attached to a syringe, allowing the fluidic cartridge to flow a amount of samples through the paper. The interaction of Cu (II) with in situ growth of Au NCs@ZIF-8 on the paper induced fluorescence quenching , which fluorescence images can be recorded and analyzed by the portable smartphone-assisted device. Furthermore, a large amount of sample solution was flowed through the Au NCs@ZIF-8 paper, enabling more Cu (II) to react with the Au NCs@ZIF-8 paper on the novel paper-based analytical device (nPAD). Cu (II) detection can be completed by nPAD in 20 mins, and the limit of detection was as low as 9.2 nM. We show the value of the paper device for on-site detection of copper (II) and indicate that it has excellent potential for clinical applications and environmental monitoring.
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Journal of Applied Spectroscopy
·
2019
·Vol. 86
·期 1
·89-95
·
IF 0.675
Wang Haojiang,Wang Xuan,Bian Wei,Sun Tijian,Cai Zongwei,Wei Jiancong
Core-shell magnetic metal organic nanocrystals were synthesized and used as matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Four nitropolycyclic aromatic hydrocarbons (nitro-PAHs) were successfully detected by using negative-ion MALDI-TOF MS without background interference. Furthermore, the magnetic nanocomposites (MNCs) coated with zeolitic imidazolate framework-8 (ZIF-8) showed excellent adsorption and enrichment capacity, and can be isolated with a magnet and directly spotted on the stainless steel plate for MALDI measurement. It was also analyzed nitro-PAHs in PM2.5 samples using the ZIF-8-coated magnetic nanocomposite as adsorbent and matrix.
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ANALYTICA CHIMICA ACTA
·
2018
·
IF 5.123
Qi Zhang,Qiuyue Zhao,Mingxuan Fu,Xinyu Fan,Haijun Lu,Haiyang Wang,Yufan Zhang,Huan Wang
In this work, carbon quantum dots (CQD) encapsulated in super small platinum nanocrystals core-shell architecture/nitrogen doped graphene hybrid nanocomposite (CQD@PDA@PtNCs-NGR) was design synthesized. Without using any capping reagent, stabilizer and surfactant, very small CQD was served as template and anchoring point for the synthesis of Pt NCs with a super small size (2.25 nm) and a uniform distribution. Meanwhile, dopamine (DA) was used as bridging agent, positioning agent and weak reducing agent to make Pt 2+ grow on the CQD. Combine the high dispersed Pt NCs with high specific surface area and high conductivity of NGR, the CQD@PDA@PtNCs-NGR shows excellent electrocatalytic performance towards the biosensing of DNA damage biomarker- 8-Hydroxy-2′-deoxyguanosine (8-OH-dG). A very low detection limit of 0.45 nM and 0.85 nM (S/N = 3), a wide linear range of 0.013 μM–109.78 μM and a high sensitivity of 7.912 μA μM −1 cm −2 and 4.190 μA μM −1 cm −2 were obtained. The fabricated CQD@PDA@PtNCs-NGR realized the detection of 8-OH-dG in human urine practical sample. Furthermore, CQD@PDA@PtNCs-NGR was applied for the determination of 8-OH-dG generated from damaged DNA and damaged guanine (G), respectively. This work effectively combines the electrochemical signal of 8-OH-dG with DNA damage, confirms the mechanism of DNA damage, which might pave a new way to establish the associations between degree of DNA damage and 8-OH-dG.
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JOURNAL OF CHROMATOGRAPHY A
·
2013
·
IF 4.612
Xue-Qing Yang,Cheng-Xiong Yang,Xiu-Ping Yan
Zeolite imidazolate framework-8 (ZIF-8) was used as the novel sorbent for on-line solid-phase extraction coupled with high-performance liquid chromatography (HPLC) for the determination of oxytetracycline (OTC), tetracycline (TC) and chlorotetracycline (CTC) in water and milk samples. 390 mg of ZIF-8 was packed into a stainless steel column (3 cm long × 4.6 mm i.d.) which was mounted on the HPLC injector valve to replace the sample loop. On-line solid-phase extraction of OTC, TC and CTC was achieved by loading sample solution at a flow rate of 3.0 mL min −1 for 10 min with the aid of a flow-injection system. The extracted analytes were subsequently eluted into a C 18 analytical column (25 cm long × 4.6 mm i.d.) for HPLC separation under isocratic condition with a mobile phase (10% MeOH–20% ACN–70% 0.02 mol L −1 oxalic acid solution) at a flow rate of 1.0 mL min −1 . Under optimized conditions, the developed method gave the enhancement factors of 35–61, the linearity range of 5–1000 μg L −1 , the detection limits of 1.5–8.0 μg L −1 , quantification limits of 5.0–26.7 μg L −1 , uncertainties of 0.9–1.1 μg L −1 , and the sample throughput of 4 samples h −1 . The recoveries of OTC, TC and CTC at 50 μg L −1 in water and milk samples ranged from 70.3% to 107.4%.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Yinlong Li,Yingqing Zhan,Yiwen Chen,Hongyi Zhang,Yajie Lei,Hongshan Jia,Fei Zhu,Xulin Yang
In order to satisfy the long-term corrosion protection of metal in harsh environments, the development of smart polymer coatings with self-repairing and self-warning functions can reach their anticipated application prospects. Herein, a new CS@HMTNs-8HQ nanocontainer, composed of a core of mesoporous hollow titanium dioxide (HMTNs) loaded with 8-hydroxyquinoline (8HQ) and a shell of chitosan (CS), was designed via simple template and vacuum-assisted technique. Grafting CS@HMTNs-8HQ nanocontainer onto the graphene oxide (GO) platform and further introducing into the waterborne epoxy (WEP) coatings imparted the healable and self-warning intelligent properties to carbon steel (Q235). It was found that the mesoporous hollow structure of HMTNs constructed by high-temperature calcination and alkaline etching yielded a high specific surface area of 190.82 m 2 /g and suitable pore size of 3 nm, thus achieving a high loading capacity of corrosion inhibitor (33.6 wt%) and ensuring long-term protection of metal substrate. The results of electrochemical impedance spectroscopy (EIS) indicated that the designed WEP coating displayed excellent healable ability. Benefiting from the synergistic effect of GO and CS@HMTNs-8HQ, the low-frequency impedance of the composite coating reached 7.63×10 9 Ω cm 2 after 90 days of immersion in 3.5 wt% NaCl, verifying its long-term protection. In addition, the WEP composite coating indicated a distinctive black-green colour in damaged areas after 120 h of salt spray testing, demonstrating the unique early warning ability. This intelligent coating with passive self-repairing and self-warning functions shows great potential prospect in practical anti-corrosion applications.
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Materials
·
2018
·Vol. 11
·期 9
·1756
·
IF 2.467
Mi Zhang,Yu Gao,Yixing Zhan,Xiaoqing Ding,Ming Wang,Xinlong Wang
Degradable, flame retardant, and flexible nanocomposite films with low dielectric constant were prepared with poly (lactic acid) (PLA), nano ZIF-8@GO, and degradable flame-retardant resorcinol di(phenyl phosphate) (RDP). The SEM results of the fractured surfaces indicated that ZIF-8@GO and RDP were dispersed uniformly in the PLA matrix. The prepared films had good mechanical properties and the tensile strength of the film with 1.5 wt% of ZIF-8@GO was increased to 48.2 MPa, compared with 38.5 MPa of pure PLA. Meanwhile, the nanocomposite films were flexible due to the toughing effect of RDP. Moreover, above 27.0% of limited oxygen index (LOI) and a VTM-0 rating were achieved for the nanocomposite films. The effects of nano ZIF-8@GO hybrids and RDP on the dielectric properties were investigated, and the results showed that ZIF-8@GO and RDP were beneficial in reducing the dielectric constant and dielectric loss of the nanocomposites.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2025
·
IF 3.8
Liu Jiannan,Xiao Wenxiang,Shao Liuwen,Chen Xinxin,Li Hua
As a critical index for heavy metal toxicity, the quantitative detection of silver ions (Ag + ) is essential for health assessment and environmental monitoring. A sensing platform based on composite gold nanoclusters with dual emissions located in the near-infrared (NIR) range has been constructed for highly sensitive Ag + quantification. Dual-emissive glutathione-functionalized gold nanoclusters (GSH-AuNCs) were first synthesized via a one-pot hydrothermal method. Then, the weak NIR emissions were effectively enhanced by introducing thiolated β-cyclodextrin to regulate the surface ligands of clusters and by ZIF-8 encapsulation to allow the spatial nanoconfinement effect. The GSH-AuNCs nanocomposite exhibited dual-channel emission peaked at 610 nm and 810 nm under 437 nm excitation. Compared with the native clusters, the fluorescent emissions were enhanced with total factors of 6.86-fold at 610 nm and 2.32-fold at 810 nm. The sensing nanocomposite can specifically complex with Ag + by the surface thiol groups and β-cyclodextrin cavities on clusters. The interaction between the fluorescent composite and Ag + changed the ligand-to-metal charge transfer (LMCT) of the clusters and caused fluorescence enhancement at 610 nm and quenching at 810 nm. This opposite variation trend in the fluorescence intensities gives the possibility of constructing a ratiometric fluorescent probe for Ag + detection. The dual-emission intensity ratio (F 610 /F 810 ) demonstrates a quantitative relationship with Ag + concentration (C Ag+ ). The sensing system possesses a linear response range of 0.02~5.00 μmol/L in pH 8.5 buffer, achieving a detection limit of 11.6 nmol/L (S/N = 3). Measurement results of real serum and water samples confirmed that the sensing platform had good accuracy and exceptional anti-interference capability for Ag + detection. Graphical Schematic synthesis of GSH-AuNCs, GSH-AuNCs@β-CD/ZIF-8 assembly, and the fluorescence sensing of Ag + .
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Cancer Cell International
·
2025
·Vol. 25
·期 1
·1-21
·
IF 6
Yang Gang,Chen Ji-Yuan,Gong Chun-Ai,Wang Rong,Han Lu,Wang Jing,Chen Min-Yan,Yuan Yong-Fang
Astragaloside (AST) has shown therapeutic potential against non-small cell lung cancer (NSCLC). However, its poor water solubility and low bioavailability limit its clinical application. To overcome these challenges, we developed an AST-loaded zeolitic imidazolate framework-8 (AST@ZIF) using supercritical fluid carbon dioxide (SCF-CO 2 ) technology. This approach aimed to enhance the solubility, bioavailability, and anti-tumor efficacy of AST. Notably, this is the first study to employ SCF-CO 2 as an anti-solvent through solution-enhanced dispersion by supercritical fluids (SEDS) for preparing drug-loaded ZIF-8. The resulting AST@ZIF-SEDS displayed a uniform hexagonal or cubic morphology, with AST transitioning from a crystalline to an amorphous state. Compared to AST@ZIF prepared using traditional methods (one-pot synthesis and solvent adsorption), AST@ZIF-SEDS demonstrated superior drug loading capacity, dispersibility, reduced residual solvent content, and improved stability. As a novel carrier, ZIF-8 effectively enhanced the solubility and bioavailability of AST while maintaining favorable biosecurity. In vivo studies further confirmed that AST@ZIF-SEDS significantly improved tumor inhibition compared with AST powder. In conclusion, SEDS technology represents a promising strategy for maximizing the therapeutic potential of ZIF-8 as a drug carrier. AST@ZIF-SEDS exhibited strong anti-tumor activity and holds potential as an effective treatment for NSCLC. Graphical abstract
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 12
·841
·
IF 5.3
Zhao Yue-Dan,Chen Ke-Yan,Xia Lei,Jin Chen-Yu,Zhao Jun-Jian,Li Hai-Jie,Xu Hou-Jun,Wang Man-Man
Mixed-ligand metal organic frameworks have received great attentions as novel sorbents for sample preparation due to their fascinating structures and intriguing functionalities. Here, we report the fabrication of mixed-linker ZIF-8-90 s with tunable properties for effervescent tablet-assisted dispersive solid-phase extraction (ET-DSPE) of polycyclic aromatic hydrocarbons (PAHs) in environmental water before HPLC separation and hydroxyl metabolites of PAHs (OH-PAHs) in urine samples prior to LC-MS/MS. ZIF-8-90 s based effervescent tablets possessed the high affinity towards analytes via Zn-O bond and π-π interaction, and afforded a great excluding ability to interfering components from urine samples. ET-DSPE of PAHs from 15 mL water sample with ZIF-8 25 -90 75 gave enhancement factors of 122–155, linear ranges of 4-10 5 ng/L, detection limits ( S/N = 3) of 1–8 ng/L, and recoveries of 81.1%-103%. For the determination of OH-PAHs, the proposed ET-DSPE method using ZIF-8 85 -90 15 allowed direct loading of 4 mL of crude human urine sample and provided the linearity range of 0.004-100 ng/mL, detection limits of 0.001–0.008 ng/mL, and recoveries of 82.1%-104%. In conclusion, ZIF-8-90-based ET-DSPE coupled with HPLC and LC-MS/MS were successfully applied to monitor both PAHs in environmental water and OH-PAHs in urine in a facile, efficient and reliable way. Graphical
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