MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Cheng Qian,Guocheng Zhou,Zhonglong Wang,Yuqian Liu,Yiqin Yang
Systematically clarifies how lignin molecular weight and sulfonation regulate CQDs fluorescence properties. • Develops green NSCDs from renewable sulfonated lignin, reducing the cost and environmental impact of CQDs. • Prepared NSCDs show high performance with 21.54% QY, 0.11 μM MnO₄⁻ LOD, and <1 min response time. • Confirms MnO₄ − fluorescence quenching is static quenching via chelation, excluding redox and energy transfer. • NSCDs sensor enables trace MnO₄ − detection in real water and promotes high-value utilization of lignin waste. Exploring a sensitive and accurate method for environmental permanganate detection is significant because of its great biotoxicity. Herein, various carbon quantum dots (CQDs) and the optimized N,S co-doped carbon quantum dots ( NSCDs ) fabricated from the hydrothermal treatment of sulfonated lignin could be used as fluorescent sensors for aqueous MnO 4 − detection. During the synthetic optimization process, compared with the positive effects of sulfonation degree increase of the sulfonated lignin and the proportion of 5-C sulfonation sites on the fluorescence intensity of CQDs, it was found that the increase of lignin molecular weight had the most significant effect on fluorescence intensity. The optimized NSCDs ( NSCDs , N from ethylenediamine, S from sulfonated lignin), with a 1.88 ± 0.37 nm particle size and Stokes shift as large as 245 nm, could emit green fluorescence under UV irradiation with a 21.54 ± 1.93% quantum yield and provide a low detection (LOD) limit of 0.11 μM for the MnO 4 − in an aqueous media with a rapid response within 1 min and good recoveries, showing good agreement with the indirect iodometric method in real water samples. Mechanistic studies suggested that the fluorescence quenching of NSCDs by MnO 4 − is predominantly a static process, likely associated with ground-state interaction between MnO 4 − and the surface functional groups of NSCDs . This work highlights precursor-structure regulation of sulfonated lignin as a distinct route for designing lignin-derived CQD sensors. Download: Download high-res image (117KB) Download: Download full-size image
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高影响因子
Materials Today Chemistry
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2026
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IF 7.4
Zicheng Chen,Junqi Zhao,Xiaoling Huang,Lizhen Chen,Yali Chen,Shaozao Tan,Jingxian Zhang
The coating has the ability to "passive defense" against bacteria. • The coating has excellent photothermal effect and peroxidase-like activity. • Photothermal therapy and chemodynamic therapy synergistically treat bacterial infections. Implant-associated infections (IAI) can lead to the failure of implant surgeries and pose a serious threat to human health. Therefore, it is crucial to construct an antibacterial coating on the surface of implants that does not cause bacterial resistance and is non-antibiotic. Photothermal therapy (PTT) and chemodynamic therapy (CDT) as alternative strategies to antibiotics for the treatment of IAI have shown great application potential. In this study, we loaded polyethylene glycol derivative-modified cuprous oxide (Cu 2 O) nanoparticles onto the surface of titanium (Ti) implants to construct a functional coating (Ti-PC). This coating exhibits peroxidase-like activity, capable of converting H 2 O 2 into ·OH for sterilization. Meanwhile, under the irradiation of near-infrared (NIR) light, the photothermal effect of the coating can enhance its own peroxidase activity, thereby improving its sterilization capacity. Furthermore, the introduction of PEG endows the coating with the ability to "passively defend" against bacteria. Overall, this multi-functional antibacterial coating is a promising solution for treating IAI.
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ACS Sustainable Chemistry & Engineering
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2026
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IF 7.6
Yaoguang Chen,Caiying Lu,Xiaoyan Pang,Xuheng Zhu,Xuliang Fan,Siqi Feng,Zhongxin Liang,Ying Xu,Liuyong Chen,Zishou Zhang
Silicon anodes exhibit exceptional capacity but suffer from rapid degradation due to significant volumetric expansion. To address this challenge, an amphiphilic binder, poly(ethylene-alt-maleic acid) (PECH), is developed via one-step hydrolysis. The vicinal dicarboxyl groups form a high-modulus hydrogen-bonded network that maintains the electrode integrity, while the ethylene segments promote affinity with conductive additives through CH−π interactions, yielding a uniform three-dimensional conductive framework. Consequently, PECH significantly enhances conventional silicon anode performance, delivering 3,141 mAh g–1 with 82% retention over 100 cycles, while also enabling the fabrication of flexible, freestanding electrodes. A systematic particle-size evaluation identifies 1 μm silicon as the optimal choice─mitigating nano-Si agglomeration and coarse-particle fracture─achieving 3,059 mAh g–1 with 81% retention over 100 cycles and excellent durability over 10,000 bending cycles. Additionally, the versatility of PECH is further demonstrated in flexible LFP cathodes (146 mAh g–1 after 500 cycles) and LFP||Si full cells (∼1.2 mAh cm–2). This work provides a molecular-level binder design strategy for high-performance and flexible lithium-ion batteries.
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高影响因子
ACS Nano
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2026
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IF 17.3
Xinnong Wang,Fan Lan,Ya Huang,Kangkang Wang,Xue-Yan Huang,Di Gao,Yuanbo Shi,Shuang Tao,Qixuan Cai,Rufan Zhang
Electrochromic technology provides an efficient method for photothermal modulation, owing to its tunable optical absorption properties. Solid-state electrolytes provide superior safety for electrochromic devices (ECDs) compared to conventional liquid electrolytes. However, the sluggish ion diffusion in solid-state electrolytes severely impedes the response speed of ECDs. In this work, an inorganic nanofiber–polymer composite-based quasi-solid electrolyte consisting of a silica (SiO2) nanofiber membrane and a poly(methyl methacrylate) (PMMA) polymer electrolyte was designed, which facilitated the rapid transportation of Li+ ions. As a nanofiller with a high aspect ratio, SiO2 nanofibers can reduce the crystallinity of polymers. Meanwhile, the mobility and arrangement of PMMA chains near the nanofiber surfaces were altered, creating an interfacial region that facilitated ion transport. Consequently, Li+ ions can migrate more rapidly along the surfaces of the SiO2 nanofibers or through the interfacial network formed around them. Moreover, the SiO2 nanofiber membrane served as a framework that provided support for the PMMA-based polymer electrolyte. The composite quasi-solid electrolyte exhibited a high ionic conductivity (4.42 mS cm–1 at 20 °C). The composite electrolyte-based ECD employed tungsten trioxide and vanadium pentoxide as electrodes and achieved reversible color changes between transparent light grayish and deep blue. The ECD exhibited a fast switching speed (0.96 s for coloring and 0.8 s for bleaching), a high coloration efficiency (CE = 247.36 cm2 C–1), and an outstanding cycling stability (maintaining 86% performance after 1500 cycles (54 785 s)).
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PubMed
高影响因子
Nature Communications
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2026
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IF 18.1
Liu Qiong,Chen Tianxiang,Lo Tsz Woon Benedict,Wang Fuxian,Ouyang Gangfeng
Photocatalytic reduction of O 2 to H 2 O 2 is generally regarded to proceed through the *O 2 hydrogenation pathway (*O 2 → *OOH), which inevitably encounters a high energy barrier proton extraction process via cleavage of the H-O bond in H 2 O. Designing a K and Cs co-modified polymeric carbon nitride (CN-KCs) to create dual-end adsorption sites as frustrated Lewis pairs for O 2 , on which the O-O breaking energy is significantly reduced and a *O 2 dissociation pathway towards photocatalytic H 2 O 2 synthesis is realized (*O 2 → 2*O, then *O + *H 2 O → H 2 O 2 ). The CN-KCs presents a competitive photocatalytic H 2 O 2 yield of 1806.6 μmolh −1 , a high quantum efficiency of 72.3% at 420 nm, and a solar-to-H 2 O 2 conversion efficiency of 6.1% with presence of biomass derivative. Here, we show that regulating dual-end adsorption sites opens a door to new *O 2 dissociation avenue for efficient conversion of O 2 to H 2 O 2 .
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PubMed
高影响因子
Advanced Science
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2026
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IF 14.1
Su Zhou,Anran Yan,Haowei Guo,Ping Chen,Qiang Chu
Ingested nanoplastics (NPs) readily translocate across the intestinal barrier due to their small size, posing a pervasive threat to human health. Current mitigation approaches, constrained to environmental water purification or postexposure injury alleviation, entail unavoidable NPs ingestion or organism damage. Effective strategies to impede NPs internalization at the lumen stage and promote safe elimination remain limited. Here, an edible biohybrid platform, composed of a natural polyphenol reductant, redox-active ferric ions, and H 2 O 2 -generating Enterococcus faecalis , is developed to trap NPs within the intestine. The platform enables persistent in situ generation of hydroxyl radicals in the intestine through Fenton reactions, accelerating the oxidative aging and subsequent NP agglomeration into micrometer-scale clusters that exceed the physiological pore-size limit of intestinal barrier. In an in vitro intestinal barrier model, the platform achieved a 96.02% NPs clearance efficiency within 24 h. Daily oral co‑administration effectively blocked NP penetration into lamina propria, alleviated intestinal inflammation, tight‑junction disruption, and mucosal damage in mice, as well as a protective effect further corroborated by the diminished NP fluorescence in C. elegans . Validated with both polystyrene and polypropylene NPs, this strategy of directed regulation of intestinal NP behaviors offers a green and generalizable approach to combat the NP exposure hazards.
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PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.6
Teng Yu,Meiting Fu,Mengyu Liu,Zhen Hong,Wenxiang Sun,Haojie Liang,Lei Wang,Qi Sun,Caixia Li
A bilayer Cu-BTC@Zn interlayer was in-situ grown on Zn anode via exchange reaction. • The upper layer, rich in carboxyl, promotes the ordered deposition of zinc ions. • The bottom layer of zincophilic Cu clusters forms dense physical protection. • Cu-BTC@Zn symmetric cell cycles over 4000 h at 3 mA cm −2 and 2000 h at 10 mA cm −2 . Aqueous zinc-ion batteries face severe challenges in practical cycling, mainly including irregular zinc dendrite growth and unstable interfacial reactions, which greatly degrade the cycling performance. Herein, via a facile immersion method relying on a one-step in-situ spontaneous displacement reaction, an organic-inorganic composite layer composed of organic components and copper nanoparticles are fabricated on the surface of the zinc metal anode. The upper layer is enriched with carboxyl groups and Cu 2+ , constructing the upper layer by coordination interactions. Acting as migration sites and transport pathways for Zn 2+ , the as-formed SEI layer induces the uniform and ordered deposition of zinc. The bottom layer is composed of zincophilic copper clusters, which can form a compact physical shielding layer on the zinc anode surface and effectively inhibit interfacial corrosion. Benefiting from the synergistic effect, the symmetric cell achieves an ultra-long cycle life of over 4000 h at 3 mA cm −2 , and still maintains a cycle life exceeding 2000 h even at a high current density of 10 mA cm −2 . Meanwhile, the Cu-BTC@Zn//MVO full battery exhibits a 57% increase in capacity retention compared with bare Zn anode after 700 cycles. Meanwhile, this work reveals the synergistic regulation mechanism of the organic-inorganic composite layer toward Zn deposition, and provides a facile and practical strategy to construct stable artificial SEI layers for high performance zinc-metal anodes. The organic copper composite interface layers with a unique bilayer structure, fabricated on the zinc anode surface via a one-step in-situ spontaneous displacement reaction. The bilayer structured SEI facilitates orderly zinc ion deposition and inhibits zinc dendrite growth. This approach offers a novel strategy for designing highly stable and durable anodes for aqueous zinc-ion batteries. Download: Download high-res image (91KB) Download: Download full-size image
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高影响因子
Advanced Energy Materials
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2026
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IF 25.5
Yibo Xu,Chenguang Zhou,Jingxuan Xu,Yunlong Yang,Yue Li,Xiangli Wen,Ningyi Yuan,Lvzhou Li,Jianning Ding
Additive engineering has propelled lab-scale perovskite solar cell efficiencies exceeding 27%, yet translating these achievements to industrial manufacturing requires multifunctional additives that simultaneously optimize crystallization, passivate defects, enhance mechanical robustness, and maintain compatibility with high-throughput coating processes. Here, we introduce glutaramide (GTA) as an all-in-one bridging coordination additive that addresses these challenges. Density functional theory calculations reveal that GTA forms a thermodynamically favored bidentate bridging coordination between adjacent [PbI 6 ] 4− octahedra. This unique configuration retards crystallization kinetics during annealing, yielding micron-scale grains with reduced defect density. Upon annealing, GTA spontaneously migrates to the film surface, where it passivates undercoordinated Pb 2+ and halide ions, toughens perovskite lattice, relieves residual stress, and increases hydrophobicity. Crucially, GTA enhances ink wettability, enabling pinhole-free, blade-coated large-area films. Small-area rigid and flexible cells achieve champion efficiencies of 26.65% and 25.22%, respectively. Remarkably, blade-coated 22.95 cm 2 modules deliver efficiencies of 24.61% (rigid) and 22.57% (flexible), retaining up to 99.6% of small-area performance. Encapsulated target devices achieve a T 90 lifetime of 1020 h under continuous 1-sun tracking, nearly doubling the control (520 h), while flexible devices demonstrate superior bending endurance. This work establishes that a single bridging additive can synergistically balance efficiency, stability, and scalability for commercial perovskite photovoltaics.
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高影响因子
Advanced Healthcare Materials
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2026
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IF 11
Mengxian Chu,Jasmine Lu Salas-Hernandez,Xiuwen Ye,Li Ming,Bowen Tan,Tsz Hei Chan,Pei Li,Zhiyong Qian,Jinfeng Liao
Repair of craniofacial bone defects remains highly challenging due to the region's complex anatomy close to vital brain marrow tissue. How to make a safe and efficient repair without disturbing surrounding tissues is critical, especially in external-stimulus-enhanced regeneration strategy. Magnetic hyperthermia therapy (MHT), due to its ability of uniform heat generation and good penetration, has gained increasing attention in bone repair. An asymmetric magnetic microspheres hybrid hydrogel was developed with magnetothermal responsiveness for targeted heating at the defect, preventing the risk of potential thermal injury to adjacent critical tissues. Guided by an external magnetic field, magnetic microspheres distributed in the upper side of the hydrogel achieved localized mild heating (40°C–42°C) under an alternating magnetic field (AMF), whereas the lower side remained within a physiologically safe temperature (< 38°C). In vitro and in vivo experiments showed that the asymmetric magnetic hydrogel under safe magnetothermal stimulation significantly enhanced the osteogenic differentiation and vascularization. Furthermore, transcriptomic analysis and histological staining suggested that this platform may convert external magnetothermal stimulation into intracellular signals by activating the PI3K-Akt pathway and upregulating key osteogenic and angiogenic markers. Overall, this asymmetric magnetothermal hydrogel offers a spatially controlled, safe, and effective strategy for bone regeneration.
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高影响因子
APPLIED SOIL ECOLOGY
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2026
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IF 5.6
Yuqian Li,Erwen Xu,Jiannan Lu,Xiurong Wu,Yicheng Zhang,Yuhan Fan,Enxian Zhou,Boyang Wang,Yuqiang Li,Xuyang Wang
Mountain soils play a critical role in global carbon cycling, yet how elevational gradients regulate soil organic carbon (SOC) component formation is unclear. We selected three elevation zones along the Qilian Mountains: the forest-grassland zone (2500–3250 m), the subalpine shrub-meadow zone (3250–3600 m), and the alpine meadow zone (3600–3800 m). Surface soil samples (0–10 cm) were collected from multiple plots within each zone. Soil properties, microbial community structure (via phospholipid fatty acid (PLFA) analysis), and SOC components (including microbial necromass carbon (MNC) via amino sugar analysis and plant residue carbon (PRC) via lignin phenol analysis) were measured. Results showed soil organic carbon, total nitrogen, and total microbial biomass increased with elevation. Conversely, the ratio of Gram-positive to Gram-negative bacteria (G + /G − ), microbial biomass per unit SOC, and the contributions of microbial necromass carbon (MNC) and plant residue carbon (PRC) to SOC declined. Structural equation modeling revealed that mean annual temperature and precipitation are primary drivers. They directly and indirectly regulate MNC and PRC formation by altering soil properties and microbial communities (e.g., fungal/bacterial ratio (F/B)). The findings demonstrate a clear hierarchical regulatory pathway: mean annual temperature (MAT) and mean annual precipitation (MAP) → soil properties (e.g., alkali-hydrolyzable nitrogen (AN), available phosphorus (AP), bulk density (BD)) → microbial community structure (PLFA/SOC, F/B) → SOC components (MNC/SOC, PRC/SOC). This indirect pathway had a much greater explanatory power than the direct influence of microbial processes. These findings highlight the overarching control of macro-climate in mountain soil carbon dynamics, providing key insights for predicting soil carbon stability under climate change.
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高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
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2026
·Vol. 24
·期 1
·184
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IF 15
Li Qingchen,Chen Lixue,Sun Yi,Wang Changyuan,Sun Yilun,Lu Kangjun,Li Lei,Sun Huijun,Liu Mozhen
PANoptosis, a distinct type of inflammation-associated programmed cell death that integrates features of apoptosis, necroptosis and pyroptosis, is closely related to the pathogenesis and progression of articular cartilage degeneration in osteoarthritis (OA). Meanwhile, excessive reactive oxygen species (ROS), pro-inflammatory pathways, and inflammatory cytokines in the OA microenvironment mutually reinforce one another, exacerbating synovial inflammation. To simultaneously target these interconnected pathological drivers, we developed an injectable nanocomposite thermosensitive hydrogel (DHA-PRO@NMs@TSH). This hierarchical system was constructed by integrating a ROS-responsive dihydroartemisinin prodrug (DHA-PRO) into Soluplus/TPGS-based nanomicelles (NMs), which were subsequently embedded within a Poloxamer-based thermosensitive hydrogel (TSH). This hierarchical and smart drug delivery system enables stable dihydroartemisinin (DHA) delivery and demonstrates a graded, ROS-triggered release profile, achieving sustained DHA retention in OA joints. The formulated system demonstrated excellent injectability, thermosensitivity, and physicomechanical stability, achieving sustained drug retention in rat joints for over 7 days, as confirmed by in vivo imaging. In vitro studies demonstrated that DHA-PRO@NMs significantly suppressed PANoptosis in chondrocytes by downregulating key markers (e.g., Bax/Bcl-2, RIPK3/p-RIPK3, NLRP3/Caspase-1/GSDMD) and inhibited inflammation by blocking the NF-κB pathway and subsequent cytokine production (e.g., TNF-α, IL-1β). In a rat OA model, treatment with DHA-PRO@NMs@TSH robustly attenuated disease progression, as evidenced by near-complete restoration of gait function, marked inhibition of cartilage degradation, a remarkable nearly 90% reduction in the Mankin score, and a comprehensive suppression of PANoptosis and inflammation pathological markers. This work not only presents a promising translational strategy for OA but also pioneers a therapeutic paradigm of leveraging advanced drug delivery system to dual-targeting PANoptosis and inflammation. Graphical abstract
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高影响因子
International Journal of Coal Science & Technology
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2026
·Vol. 13
·期 1
·1
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IF 10.1
Eskanlou Amir,Arnold Barbara J.
The prevalence of coal workers’ pneumoconiosis (CWP) has been on the rise among U.S. coal miners since the early 2000s and is most pronounced in central Appalachia. Such adverse effects on human health are partly linked to the toxicity of respirable coal mine dust particles. In this review, we present an overview of the characteristics and health effects of the coal dust components, as well as the origin, chemistry, and mechanisms for their potential toxicity. Toxicity of coal mine dust is linked to the surface chemistry and bioactivity of the composing particles, such as coal, crystalline silica (quartz), pyrite, and sometimes diesel particulate matter. Formation of reactive oxygen species, such as •OH on the surface of these particles, contributes to the toxicity of coal dust. Various mechanisms including the metal-micelle coating, polymer-coating, chelation of the surface metal ions, and surface silanization, have been proposed in previous studies for the reduction or inhibition of the toxicity of coal dust particles. However, due to the complexity in surface chemistry of the various minerals and coal, there is no single universal detoxification mechanism for coal dust. One feasible remedy to address the proposed mechanisms of toxicity is the use of chemical additives as wetting agents. Important considerations for this approach include particle size and aging, mineralogy, morphology, chemical composition, solubility, surface charge, and synergistic effects of the composing phases. Additional factors to consider are the solution quality and composition, coal rank, and the potential hazards and costs associated with the chosen chemical agents.
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高影响因子
危险品化学品经营许可证（带存储）