ACS Nano
·
2026
·
IF 17.3
Junhui Zhang,Chunrong Ma,Guangshuai Han,Zhezheng Ding,Yan Wang,Daqian Wang,Jinnuo Li,Bing Sun,Timing Fang,Xiaomin Liu,Xiao Tang
The development of high-energy lithium-ion batteries is crucial for next-generation energy storage and electric vehicle/aircraft technologies; however, their development is hindered by conventional electrolyte designs, which perform poorly across wide temperature ranges. Herein, entropy-enhanced electrolytes have been developed for graphite||LiNi0.9Co0.05Mn0.05O2 (NCM955) cells by a data-driven approach. Entropy-enhanced electrolytes feature diversified solvation structures that significantly improve thermodynamic stability and ionic kinetics. Furthermore, the film-forming ability of both the anodes and cathodes under various conditions is systematically investigated. One formulation with a moderate entropy value proves particularly effective, facilitating the formation of stable electrode/electrolyte interphases, which enables graphite||NCM955 cells with superior cycling stability across a wide temperature range. Consequently, the as-assembled graphite||NCM955 cells with the entropy-enhanced electrolyte can deliver a remarkable long-term lifespan (>1500 cycles) with a high energy density, maintaining high capacity retention from −30 to 70 °C. This work provides strategic insights for developing next-generation electrolytes for high-energy-density and all-climate-adaptive lithium-ion batteries.
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高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2026
·
IF 6.7
Lulu Zhang,Zehao Li,Wanying Wang,Yingjie Feng,Jinchu Yang,Yongming Xu,Zhenzhen Huang,Nannan Wang,Kaijing Yin
Dihydrocarvone is an important flavor compound and chiral building block obtained through the ene reductase (ER)-mediated reduction of carvone. In this study, a new ER, KlebER1, from Klebsiella sp. O852 was identified and characterized. Optimal enzyme activity occurred at 40 °C and pH 7, with approximately 80% activity retained after incubation at 20–40 °C for 3 h. Based on sequence alignment, alanine scanning, and molecular docking analyses, a site-directed mutation (A303N) was introduced, resulting in a 1.73-fold enhancement in activity. Finally, an enzymatic cascade system incorporating the A303N mutant and glucose dehydrogenase for coenzyme regeneration was constructed both in vivo and in vitro for dihydrocarvone production. This biocatalytic system achieved a dihydrocarvone concentration of 5.88 mmol/L and a conversion rate of 99%, representing a significant improvement compared to the single use of A303N mutant. This study lays the foundation for investigating the function and modification of ERs and promoting the efficient biosynthesis of dihydrocarvone.
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ACS Applied Nano Materials
·
2026
·
IF 5.8
Qingjie Yang,Qirong Zhu,Xueting Liu,Qingxiu Yang,Mingzhe Li,Siwen Yu,Jianjun Guo,Dingyi Tong,Aihua Sun,Yuchuan Cheng
Current CMP processes still face significant challenges in minimizing or eliminating the use of additional oxidants and/or external energy inputs. In this work, we present a green and highly efficient CMP strategy that ingeniously harnesses the piezoelectric effect of barium titanate (BaTiO3) to enhance the polishing process. A five-factor orthogonal experimental design was employed to systematically investigate the influence of key process parameters on the material removal rate (MRR) during silicon wafer polishing. Through parameter optimization, the process achieved an exceptionally high MRR of 436 nm·min–1, accompanied by an ultralow surface roughness (Ra = 0.253 nm). Under the applied polishing pressure, tetragonal-phase BaTiO3 particles generate reactive oxygen species (ROS) in situ. The addition of a small amount of hydrogen peroxide (H2O2) further amplifies this effect: H2O2 acts not only as a catalytic substrate but also as an electron scavenger, significantly accelerating the formation of a soft and easily removable silicate oxide layer on the silicon surface. Simultaneously, the BaTiO3 particles serve as abrasives, mechanically removing this oxide layer and thereby establishing a synergistic “oxidation–abrasion” mechanism. The mechanism was confirmed by ESR and XPS characterization. Notably, the entire polishing process requires no additional energy input such as heating, light irradiation, or external electric fields and operates efficiently using only the standard mechanical action of conventional CMP equipment. This approach thus offers an innovative, environmentally sustainable, and highly effective solution for global silicon wafer planarization.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
·
IF 6.7
Tong Xiao,Shuai Liu,Ting Liu,Guanbin Peng,Qingsong Meng,Xinshun Yuan,Jingyi Wu,Weimin Wang,Kaikai Song,Guoxing Li,Wei Chu,Lina Hu
The development of aqueous aluminum metal batteries is hampered by severe parasitic side reactions at the aluminum metal anode/electrolyte interface. In this work, aluminum-based amorphous alloy anodes are applied to aqueous aluminum metal batteries for the first time. Amorphous aluminum alloys exhibit higher adsorption energy for Al atoms and can regulate the Al 3 + deposition potential, thereby offering a kinetic advantage over the hydrogen evolution reaction. Their isotropic deposition behavior suppresses aluminum dendrite growth, while the amorphous structure also improves interfacial chemistry, mitigating anode self-corrosion and passivation. The coupling between the adsorbed atoms and the Al 85 Ni 10 Ce 5 substrate electrons is stronger, leading to more stable adsorption. Symmetric cells assembled with Al 85 Ni 10 Ce 5 amorphous alloys demonstrated stable cycling for 5000 h, which present the best cycling performance for bare anode for aqueous aluminum metal batteries at 0.1 mA cm −2 and 0.1 mAh cm −2 . Moreover, a full cell incorporating this anode with a K 2 CoFe(CN) 6 cathode delivered a high initial discharge capacity of 98.3 mAh g −1 . This work provides not only a scalable strategy for high performance aqueous aluminum metal batteries, but also theoretical guidance for the electrode optimization of other metal battery systems.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Kaiyue Cui,Weibing Zhong,Shifan Song,Yanyan Li,Yi Xiong,Mufang Li,Qiang Zhu,Shengyuan Yang,Yiming Ke,Dong Wang
Solvent-free ionic elastomer with orthogonal electrical response • High-performance sensing: GF of 8.24 and TCR of 2.88%/°C • Machine learning decouples R/C signals into strain and temperature (R 2 ≥ 0.90) • Demonstrates simultaneous motion and heat detection for firefighters The simultaneous perception of multiple physical stimuli is essential for intelligent soft robotics and personalized healthcare. However, the concurrent detection of strain and temperature is fundamentally hindered by signal crosstalk, which compromises accuracy and reliability. Existing solutions, often relying on heterogeneous integration or intricate circuitry, inevitably sacrifice mechanical stability and scalability. Here, we introduce a sensing paradigm that leverages intrinsic material properties to achieve physical signal orthogonality. We design a solvent-free ion-conductive elastomer that exhibits antagonistic electrical responses to strain and temperature: its resistance increases but capacitance decreases upon stretching, whereas both resistance and capacitance increase with heating. This inherent signal decoupling stems from distinct ion migration and interfacial polarization mechanisms under mechanical and thermal stimuli. To translate this orthogonal relationship into precise quantitative readings, we employ a random forest regression model that directly maps the coupled resistance-capacitance signals to strain and temperature values, bypassing the need for complex analytical inversion. Our sensor achieves high-fidelity decoding, with determination coefficients of 0.90 for strain and 0.94 for temperature. It also maintains robust performance over 300 stretching cycles. We further demonstrate its practical utility in a firefighter safety warning system that simultaneously monitors body motion and detects extreme heat exposure. This work establishes a material-centric and algorithm-powered roadmap for multi perception, paving the way for high-fidelity sensing in complex environments. Download: Download high-res image (297KB) Download: Download full-size image
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产品关联
DOI
高影响因子
CHEMPHYSCHEM
·
2026
·Vol. 27
·期 12
·e202500912
·
IF 2.4
Ruipeng Hao,Fangyuan He,Wanyu Xie,Ming Wei,Xuwen Gao,Wenbo Lu
Rapid and efficient detection of dopamine is crucial for disease prevention and clinical diagnosis. Herein, ZnCoP nanopolyhedra synthesized via a metal–organic framework (MOF)-derived phosphidation route are employed as an electrocatalyst for electrochemical dopamine sensing. The constructed sensor exhibits outstanding analytical performance, featuring a wide linear range (0.5–1500 μM), high sensitivity (1038 μA mM −1 cm −2 ), and a low detection limit of 0.19 μM. Additionally, the sensor demonstrates excellent selectivity, long-term stability, and reliable repeatability. The superior performance is attributed to the well-defined polyhedral architecture inherited from the MOF precursor, which offers abundant electroactive sites and facilitates efficient electron transfer. These results establish ZnCoP nanopolyhedra as a promising sensing platform for dopamine detection, with strong potential for applications in medical diagnostics and bioanalytical monitoring. Graphical Metal–organic framework (MOF)-derived ZnCoP nanopolyhedra are synthesized via a direct phosphidation strategy and serve as an efficient electrocatalyst for dopamine detection. The material retains the polyhedral morphology of the MOF precursor with a roughened surface, providing abundant active sites and enhanced conductivity. Benefiting from these features, the electrochemical sensor delivers a wide linear range (0.5–1500 μM), a low detection limit (0.19 μM), and high sensitivity (1038 μA mM −1 cm −2 ), along with excellent selectivity, stability, and reproducibility.
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NATURE BIOTECHNOLOGY
·
2025
·
IF 41.7
Li Guangye,Chen Guo,Yuan Guo-Hua,Wei Jia,Ni Qingyang,Wu Jing,Yang Bei,Yang Li,Chen Jia
RNA editing can be a promising therapeutic approach. However, ectopic expression of RNA editing enzymes has been shown to trigger off-target editing. Here we identified adenosine deaminase acting on RNA (ADAR) inhibitors (ADIs) that suppress the activity of the fused ADAR2 deamination domain (ADAR2 DD ). Using these specific ADIs, we develop an RNA transformer adenosine base editor (RtABE) with high specificity. Fusing ADI to ADAR2 DD , RtABE remains inactive until it binds to its target site. After binding to the target site, ADI is cleaved from ADAR2 DD , and RtABE becomes active. RtABE can induce efficient editing in broad sequence contexts, including UAN, AAN, CAN and GAN. Using an adeno-associated virus for delivery of RtABE enables therapeutic RNA correction and restoration of α- l -iduronidase activity in Hurler syndrome mice with no substantial off-target editing. RtABE is a specific and efficient RNA editing system with a broad scope that may be a better alternative to existing RNA editing tools.
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INORGANIC CHEMISTRY
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2026
·
IF 4.6
Ze-Jia Shen,Lin Cheng,Xin Hao,Yi-Ming Zhao,Shuaihua Wang,Kai-Yao Wang
The efficient removal of Ni2+ from radioactive wastewater is crucial for environmental protection and nuclear safety, yet current ion exchangers often exhibit limited stability and selectivity. Herein, we report an open-framework gallium–antimony sulfide, K3.6[NH4]0.1[CH3NH3]0.3Ga4SbS9SH·0.9H2O (GaSbS-2K), constructed from supertetrahedral T2-{Ga4S9SH} clusters and asymmetric Sb bridges. Its three-dimensional framework features intersecting chiral channels and tetrahedral voids that facilitate ion diffusion and exchange. GaSbS-2K exhibits rapid Ni2+ adsorption, achieving 67.66% uptake within 2 min and 97.54% removal at equilibrium, with a pseudo-second-order rate constant of 0.318 g mg–1 min–1. The material shows a maximum adsorption capacity of 90.78 ± 2.74 mg g–1 under neutral conditions and remains stable across a wide pH range (3–12). It retains strong selectivity for Ni2+ in the presence of competing ions, maintaining >72% removal even in seawater. The rapid adsorption kinetics enable continuous-flow applications in both fixed-bed columns and composite membranes, achieving >99% removal of Ni2+. Notably, the GaSbS-2K/PTFE membrane with an 80 μm active layer completely removes Ni2+ from 1000 mL of solution at a flux of 1.91 mL min–1 cm–2 with only 0.25 s of contact time. Combined with its facile synthesis, radiation stability, and regenerability, GaSbS-2K represents a promising adsorbent for radionuclide-contaminated wastewater treatment.
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ACS Catalysis
·
2026
·
IF 13.6
Zhe Zhang,Yan Zhang,Zhen Du,Xiaomin Zheng,Hongrui Xu,Yanxia Lin,Peng Kong,Hong Li,Jianchun Cao,Cheng Zhang,Shan Li,Yong Xu,Lei Zhang
7α, 24R-Dihydroxy-5α-cholestan-3-one serves as a key intermediate in the synthesis of squalamine. In this study, a simple and efficient three-step chemo-enzymatic method was developed with a total yield of 61% by utilizing an engineered ketoreductase from Novosphingobium aromaticivorans (NaKRED). NaKRED was a NADH-dependent short-chain alcohol dehydrogenase, and the mutant variant (Y199A/N149L) exhibited a 94.3% conversion rate of substrate 1a and 99.8% diastereoselectivity. At the optimized reaction system, the substrate concentration at 10 mM afforded a product yield of 51.2% and a titer of 2.153 g/L while maintaining stereoselectivity above 99.8%. Crystal structures of the NAD+-free and NAD+-bound wild-type and Y199A/N149L mutant revealed that the intrinsically Ser-Tyr-Lys catalytic triad machinery formed a prominent and flexible ammonium cation hole into which the NADH molecule was buried. NADH featured two different conformations in tetrameric and octameric ketoreductases, and mediated the catalytic activity by undergoing a conformational change to form a productive substrate binding conformation (A-form) based on the crystal structure and molecular dynamics simulation. Our research presented not only an effective strategy to produce the key squalamine intermediate but also revealed a previously unrecognized NADH-regulated mechanism in KRED-catalyzed ketone reduction.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Cheng Qian,Guocheng Zhou,Zhonglong Wang,Yuqian Liu,Yiqin Yang
Systematically clarifies how lignin molecular weight and sulfonation regulate CQDs fluorescence properties. • Develops green NSCDs from renewable sulfonated lignin, reducing the cost and environmental impact of CQDs. • Prepared NSCDs show high performance with 21.54% QY, 0.11 μM MnO₄⁻ LOD, and <1 min response time. • Confirms MnO₄ − fluorescence quenching is static quenching via chelation, excluding redox and energy transfer. • NSCDs sensor enables trace MnO₄ − detection in real water and promotes high-value utilization of lignin waste. Exploring a sensitive and accurate method for environmental permanganate detection is significant because of its great biotoxicity. Herein, various carbon quantum dots (CQDs) and the optimized N,S co-doped carbon quantum dots ( NSCDs ) fabricated from the hydrothermal treatment of sulfonated lignin could be used as fluorescent sensors for aqueous MnO 4 − detection. During the synthetic optimization process, compared with the positive effects of sulfonation degree increase of the sulfonated lignin and the proportion of 5-C sulfonation sites on the fluorescence intensity of CQDs, it was found that the increase of lignin molecular weight had the most significant effect on fluorescence intensity. The optimized NSCDs ( NSCDs , N from ethylenediamine, S from sulfonated lignin), with a 1.88 ± 0.37 nm particle size and Stokes shift as large as 245 nm, could emit green fluorescence under UV irradiation with a 21.54 ± 1.93% quantum yield and provide a low detection (LOD) limit of 0.11 μM for the MnO 4 − in an aqueous media with a rapid response within 1 min and good recoveries, showing good agreement with the indirect iodometric method in real water samples. Mechanistic studies suggested that the fluorescence quenching of NSCDs by MnO 4 − is predominantly a static process, likely associated with ground-state interaction between MnO 4 − and the surface functional groups of NSCDs . This work highlights precursor-structure regulation of sulfonated lignin as a distinct route for designing lignin-derived CQD sensors. Download: Download high-res image (117KB) Download: Download full-size image
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Materials Today Chemistry
·
2026
·
IF 7.4
Zicheng Chen,Junqi Zhao,Xiaoling Huang,Lizhen Chen,Yali Chen,Shaozao Tan,Jingxian Zhang
The coating has the ability to "passive defense" against bacteria. • The coating has excellent photothermal effect and peroxidase-like activity. • Photothermal therapy and chemodynamic therapy synergistically treat bacterial infections. Implant-associated infections (IAI) can lead to the failure of implant surgeries and pose a serious threat to human health. Therefore, it is crucial to construct an antibacterial coating on the surface of implants that does not cause bacterial resistance and is non-antibiotic. Photothermal therapy (PTT) and chemodynamic therapy (CDT) as alternative strategies to antibiotics for the treatment of IAI have shown great application potential. In this study, we loaded polyethylene glycol derivative-modified cuprous oxide (Cu 2 O) nanoparticles onto the surface of titanium (Ti) implants to construct a functional coating (Ti-PC). This coating exhibits peroxidase-like activity, capable of converting H 2 O 2 into ·OH for sterilization. Meanwhile, under the irradiation of near-infrared (NIR) light, the photothermal effect of the coating can enhance its own peroxidase activity, thereby improving its sterilization capacity. Furthermore, the introduction of PEG endows the coating with the ability to "passively defend" against bacteria. Overall, this multi-functional antibacterial coating is a promising solution for treating IAI.
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ACS Sustainable Chemistry & Engineering
·
2026
·
IF 7.6
Yaoguang Chen,Caiying Lu,Xiaoyan Pang,Xuheng Zhu,Xuliang Fan,Siqi Feng,Zhongxin Liang,Ying Xu,Liuyong Chen,Zishou Zhang
Silicon anodes exhibit exceptional capacity but suffer from rapid degradation due to significant volumetric expansion. To address this challenge, an amphiphilic binder, poly(ethylene-alt-maleic acid) (PECH), is developed via one-step hydrolysis. The vicinal dicarboxyl groups form a high-modulus hydrogen-bonded network that maintains the electrode integrity, while the ethylene segments promote affinity with conductive additives through CH−π interactions, yielding a uniform three-dimensional conductive framework. Consequently, PECH significantly enhances conventional silicon anode performance, delivering 3,141 mAh g–1 with 82% retention over 100 cycles, while also enabling the fabrication of flexible, freestanding electrodes. A systematic particle-size evaluation identifies 1 μm silicon as the optimal choice─mitigating nano-Si agglomeration and coarse-particle fracture─achieving 3,059 mAh g–1 with 81% retention over 100 cycles and excellent durability over 10,000 bending cycles. Additionally, the versatility of PECH is further demonstrated in flexible LFP cathodes (146 mAh g–1 after 500 cycles) and LFP||Si full cells (∼1.2 mAh cm–2). This work provides a molecular-level binder design strategy for high-performance and flexible lithium-ion batteries.
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