FOOD CHEMISTRY
·
2023
·
IF 8.8
Guoqiang Guo,Tingting Li,Ziyi Liu,Xinyu Luo,Ting Zhang,Siyuan Tang,Xu Wang,Da Chen
Recently, converting bio-waste into bio-asset and implementing a portable sensing instrument for pollutant monitoring has been highly desirable and challenging. Herein, biomass-derived nitrogen-doped carbon dots (CDs) are prepared hydrothermally and emit blue fluorescence (470 nm) with a high quantum yield of 23.2%. Significantly, CDs can serve as a pH-modulated fluorescence switching nano-sensor to detect 4-NP from 0.054 to 68 μM with low detection limit (LOD, 54 nM) and limit of quantification (LOQ, 181 nM) based on inner filter effect. Moreover, the satisfactory recovery of 101.8–107.5% is gained in practical sample monitoring. Furthermore, a smartphone-integrated optosensing device with CDs-based film is developed for detecting 4-NP with LOD and LOQ of 0.110 μM and 0.350 μM. Concomitantly, the practicability of this device is further validated in several crop samples with satisfactory recovery rates of 101.6–108.6%. Therefore, this work provides a reliable way and a prospective application for on-site 4-NP monitoring in food.
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高影响因子
ENVIRONMENTAL TOXICOLOGY
·
2023
·
IF 4.5
You Xiao,Yuanyuan He,Chongsi Xu,Mei Li,Fan Hu,Wei Wang,Zhenquan Wang,Yi Cao
MoS 2 nanosheets (NSs) are novel 2D nanomaterials (NMs) being used in many important fields. Recently, we proposed the need to evaluate the influences of NMs on Kruppel-like factors (KLFs) even if these materials are relatively biocompatible. In this study, we investigated the influences of MoS 2 NSs or bulk on KLF4 signaling pathway in 3D Caco-2 spheroids in vitro and mouse intestines in vivo. Through the analysis of our previous RNA-sequencing data, we found that exposure to MoS 2 NSs or bulk activated KLF4 expression in 3D Caco-2 spheroids. Consistently, these materials also activated KLF4-related gene ontology (GO) terms and down-regulated a panel of KLF4-downstream genes. To verify these findings, we repeatedly exposed mice to MoS 2 NSs or bulk materials via intragastrical administration (1 mg/kg bodyweight, once a day, for 4 days). It was shown that oral exposure to these materials decreased bodyweight, leading to relatively higher organ coefficients. As expected, exposure to both types of materials increased Mo elements as well as other trace elements, such as Zn, Fe, and Mn in mouse intestines. The exposure also induced morphological changes of intestines, such as shortening of intestinal villi and decreased crypt depth, which may result in decreased intestinal lipid staining. Consistent with RNA-sequencing data, we found that material exposure increased KLF4 protein staining in mouse intestines and decreased two KLF4 downstream proteins, namely extracellular signal-regulated kinase (ERK) and serine/threonine kinase (AKT). We concluded that MoS 2 materials were capable to activate KLF4-signaling pathway in intestines both in vivo and in vitro.
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CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Jia Sun,Yinsheng Gu,Yingwei Lu,Juntao Hu,Tao Chen,Changfei Zhu,Paifeng Luo
Nowadays, the MA-FA mixed-cation perovskite solar cells (PSCs), demonstrating much higher stability than that of single-cation MAPbI 3 or FAPbI 3 , are still encountering a low-efficiency issue. The main reason is that there existing a lot of defects in SnO 2 electron transport layers (ETLs) and perovskite absorbers. Herein, we develop a synergistic strategy of Rubidium Chloride (RbCl) doping and 4- tert -butylbenzylammonium iodide (tBBAI) passivation to fabricate high-performance MA x FA 1-x PbI 3 mixed-cation PSCs. The alkali halide RbCl is first selected as a novel doping additive to regulate the film properties of SnO 2 and perovskites. Research shows that the negative Cl - ions can combine with uncoordinated Sn 4+ ions due to their strong bonding ability, which can passivate the oxygen-vacancy-related defects and enhance the charge transport of SnO 2 ETLs. Meanwhile, the doped Rb + and Cl - ions may diffuse into perovskite lattices to promote grain growth and reduce the defects of perovskites. Besides, we employ an organic halide salt tBBAI to passivate perovskites and suppress surface defects. Results of deep level transient spectroscopy (DLTS) indicate that SnO 2 and SnO 2 -RbCl based devices have deeper hole traps and large trap densities (Δ E = 0.92 eV, N T = 1.10 × 10 16 cm −3 ; ΔE = 0.93 eV, N T = 2.16 × 10 15 cm −3 ); while tBBAI-treated SnO 2 -RbCl-based devices own a shallower hole trap and a smaller trap density ( ΔE = 0.72 eV, N T = 2.44 × 10 13 cm −3 ); and the corresponding I Pb and I (MA/FA) antisite defeats are also identified. Therefore, our synergistic strategy is effectively able to reduce the defect density and suppress the non-radiative recombination. Consequently, the best-performance MA 0.85 FA 0.15 PbI 3 PSCs achieve an impressive power conversion efficiency (PCE) of 22.54% with a large open circuit voltage ( V oc ) of 1.16 V, which are by far the highest values of MA 0.85 FA 0.15 PbI 3 mixed-cation PSCs.
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JOURNAL OF VIROLOGICAL METHODS
·
2023
·
IF 3.1
Shuzhen Chen,Qingdong Luan,Shimei Qiu,Yue Zhao,Yanjin Lu,Shufang Sun,Jianlin Wang,Yanbo Yin
To detect the antibody against fowl adenovirus serotype 4 (FAdV-4) in clinical practice, the latex agglutination test (LAT) was developed by using the Fiber-2 protein of FAdV-4 as an antigen bound to sensitized latex microspheres . The concentration, time, and temperature of sensitization latex microspheres by the Fiber-2 protein were studied and optimized; the specificity, sensitivity, and repeatability of LAT were tested; and the method developed in the study was applied. The results showed that the optimum sensitization concentration of Fiber-2 protein was 0.8 mg/mL, the time was 120 min, and the temperature was 37 ℃. Except for antiserum against FAdV-4 and FAdV-10, LAT developed in the study could not agglutinate antisera against FAdV-1, FAdV-2, FAdV-3, FAdV-4, FAdV-5, FAdV-6, FAdV-8a, FAdV-8b, FAdV-11, Newcastle disease virus , infectious bronchitis virus , egg drop syndrome virus and Clostridium perfringens . Compared with the commercial FAdV-4 ELISA Kit, the titers in 21 clinical samples were low when tested by the developed LAT method, but there was no significant difference. The coefficients of variation among different batches and the same batch of latex-sensitized particles were between 0 % and 13.3 % and 0–8.7 %, respectively. The critical value of immune protective antibody against FAdV-4 was 2 5 , and the titers in 40.9 % of clinical samples were higher than the immune critical point. The results showed that the Fiber-2-based LAT developed in the study has the characteristics of high specificity, sensitivity and repeatability, has the advantages of free equipment, long shelf life, and fast and easy operation, and is an effective and convenient method for serological diagnosis of FAdV-4 infection and evaluating the efficacy of vaccines.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Jiaxin Zhu,Zekun Liu,Yihua Chen,Zhiqiang Chen,Hang Ma,Jian Sun,Liao Meng,Tongzhou Liu
The discharge of widely used fluorinated aromatics (FAs) leads to their notoriously high persistence and toxicity in natural environments. Defluorination is the key step for FAs pollutants detoxification. Due to its easy operation and mild reaction conditions, hydrodefluorination (HDF), especially electrochemical HDF, is a promising approach for FAs detoxification. A comprehensive and detailed investigation of the effective cathode and mechanism insights are contributable for the development of effective FAs defluorination techniques. In this study, 4-fluorophenol (4-FP) was selected as a model compound to optimize the electrochemical HDF process and understand the reaction mechanism. Cathode coating material investigation revealed that Rh outperformed Pd due to its higher reactivity towards C F bond cleavage. The Rh coating was primarily elemental and in Rh(1 1 1) crystalline form which helped store the generated atomic hydrogen (H*). Reaction conditions optimizations showed 4-FP degradation favored acidic > alkaline > neutral environment and a cell potential higher than −3 V was required for efficient 4-FP degradation. Dissolved oxygen (DO) negatively affected 4-FP degradation and the rapid 4-FP decay only occurred after DO depleted in the solution. Based on quenching experiments and ESR analysis, H* was determined as the main reactive species. In situ Raman characterization suggested that electrochemical 4-FP degradation was initiated by 4-FP adsorption through R···F···Rh bridging and H* generation/adsorption on Rh coated cathode, resulting in phenol generation. The generated phenol further experienced hydrogenation to yield cyclohexanone and cyclohexanol with lower toxicity and better biodegradation potential, demonstrating that electrochemical treatment of 4-FP simultaneously achieved defluorination along with detoxification. The outcomes of this work provide support for electrocatalyst technology development towards efficient FAs treatment while providing in-depth observation of the electrochemical HDF process.
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高影响因子
JOURNAL OF SOLUTION CHEMISTRY
·
2023
·Vol. 52
·期 7
·762-789
·
IF 1.2
Li Min,Zhang Xiaocheng,Yu Yingmin,Liu Lanmu
The extractive distillation was used to separate ethylbenzene and m-xylene. After the solvent screening, 1,2,4-trichlorobenzene was chosen as the extractive solvent. The vapor–liquid equilibrium (VLE) of binary mixtures of m-xylene, ethylbenzene, and 1,2,4-trichlorobenzene was measured at 101.33 kPa. The measurements were taken with a modified Rose equilibrium still. The Wisniak’s test was used to assess the thermodynamic consistency of the VLE experimental results. To obtain the binary interaction parameters, the binary VLE experimental data were correlated with the NRTL, Wilson, and UNIQUAC activity coefficient models. The results showed that three models all fit the experimental values of three binary systems well, and the ternary VLE data of m-xylene + ethylbenzene + 1,2,4-trichlorobenzene were estimated using Aspen Plus V11 based on these model parameters. The experimental data agree well with the estimation values generated from three models. Finally, the effect of 1,2,4-trichlorobenzene as an extractant was analyzed, and it is proved to have a good influence on the separation of ethylbenzene from mixed xylenes by extractive distillation.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2019
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IF 3.218
Haiyan Jia,Taotao Yang,Quan Xu,Jingkun Xu,Limin Lu,Yongfang Yu,Ping Li
In this paper, core-shell structured poly (indole‑5‑carboxylic acid) @ poly (3, 4‑ethylenedioxythiophene) (PIn‑5‑COOH@PEDOT) composite was prepared by a facile two-step chemical oxidation method. The composite possesses large specific surface area, high stability, good electrical conductivity and redox activity, which was designed as label-free electrochemical immunosensing platform for the monitor of the prostate specific antigen (PSA). In this sensing system, PIn-5-COOH served as both signal molecule and antibody carrier. The coating PEDOT was used to enhance the conductivity and stability of PIn-5-COOH. Benefiting from the synergistic effects between PIn-5-COOH and PEDOT, the fabricated immunosensor exhibited a wide linear range of 0.01–25 ng mL −1 and low detection limit of 3.4 pg mL −1 (S/N = 3) for the assay of PSA, coupled with good selectivity, reproducibility and stability. The immunosensor is simple, sensitive, specific and reproducible, which could provide a potential approach for clinical diagnosis.
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高影响因子
TALANTA
·
2019
·
IF 4.916
Wenfang Deng,Chang Cheng,Hui Yang,Hui Wang,Yueming Tan,Qingji Xie,Ming Ma,Shouzhuo Yao
We report here a sensitive method for immunoassay of Staphylococcus aureus ( S. aureus ) based on colorimetric and fluorescent responses of 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl) to l -cysteine (Cys). S. aureus cells were separated from samples by immunomagnetic nanoparticles and labeled with Cys-encapsulated liposome ( [email protected] ) immuno-nanocapsules. After mangnetic separation, the [email protected] immuno-nanocapsules linked to bacterial cells were destructed by Tween-20, and then the released Cys molecules reacted with NBD-Cl to generate colorimetric and fluorescent signals. Due to the amplification effect of liposome nanocapsules , the high capture efficiency of immunomagnetic nanoparticles, and the high responses of NBD-Cl to Cys, the detection limits for colorimetric and fluorescent detection of S. aureus were as low as 10 and 1 CFU mL −1 , respectively. The proposed method was successfully used to detect S. aureus in milk samples. This work has provided a novel NBD-Cl based colorimetric and fluorescent platform for immunoassay.
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高影响因子
DYES AND PIGMENTS
·
2018
·
IF 3.767
Wansheng Zong,Lixin Wang,Qing Guo,Juan Li,Wenbo Wu,Yingliang Liu,Shengang Xu,Shaokui Cao
A hyper-structured molecule (HSM) CRA-DR1 and a model molecule Ph-DR1 for photorefractive (PR) application under non-electric field were designed and synthesized via highly reactive “click” reaction between alkynyl derivatives of calix [4]resorcinarene (CRA) or resorcinol and an azide derivative of disperse red 1 (DR1) in satisfactory yields. XRD pattern and UV–Vis absorption spectra indicated that the CRA-DR1 with three-dimensional (3D) CRA core could effectively decrease the aggregation, packing and crystallization of the nonlinear optical (NLO) chromophores . AFM images showed a smooth and pinhole-free morphology of the CRA-DR1 film. Two-beam coupling (TBC) experiment was used to test the photorefractive performance in optically transparent films of Ph-DR1 and CRA-DR1 doped with [6,6]-phenyl-C 61 -butyric acid methyl ester (PCBM) as a photosensitizer and N -ethyl-carbazole (ECz) as a plasticizer . Without poling and without external electric filed, the coupling gain coefficient obtained in the CRA-DR1-based composite is 147.4 cm −1 , which is higher than that of Ph-DR1-based composite (132.6 cm −1 ) owing to its asymmetrical 3D CRA core. Coupled with its convenient synthesis and commercial DR1, CRA-DR1 could serve as a good candidate for PR application.
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ACS Catalysis
·
2018
·
IF 11.384
Cheng Liang,Qiyi Ma,Haoran Yuan,Yongtao Wang,Jianyong Mao,Zhirong Chen,Jia Yao,Haoran Li
An investigation of aerobic oxidation of 2-methoxy-4-methylphenol to vanillin catalyzed by a number of cobalt salts, complexes, oxides, and hydroxides in alkaline solutions is reported. A good yield of vanillin (90%) was obtained when CoCl2 was used as the catalyst, while a poor yield (6%) was obtained with Co3O4. Unexpectedly, however, the Co3O4 catalytic activity was restored after heating in an alcoholic solution of NaOH for 24 h, producing a good yield of vanillin (85%). The recovered catalytic activity of Co3O4 indicated a conversion of inactivated heterogeneous particles to activated particles. In addition, precipitates were generated when “homogeneous” CoCl2 was employed as a catalyst, making us wonder about the true nature of the catalyst in this reaction. A series of experiments are described, including kinetic studies, filtration tests, centrifugation tests, dynamic light scattering, transmission electron microscopy, X-ray photoelectron spectroscopy, and powder X-ray diffraction, for the investigation of the true catalyst under catalytic conditions. The key observations led to the conclusion that the cobalt salts and complexes act as precatalysts that transform to cobalt oxide/hydroxide [CoOx(OH)y] nanoparticles, which is responsible for the benzylic C(sp3)–H oxyfunctionalization of 2-methoxy-4-methylphenol. Additionally, the size of the particles is decisive for catalyst performance. The nature of the active nanoparticles was also studied. With regard to the identification of homogeneous or heterogeneous catalysis, this study provides a complement to existing catalytic reaction types.
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高影响因子
ACS Applied Energy Materials
·
2018
·
IF 0
Junjie Fu,Jie Fu,Qingwen Tian,Houlin Wang,Fengming Zhao,Jun Kong,Xiangyun Zhao,Sixin Wu
The Se content in a Cu2ZnSn(S, Se)4 absorber layer has a significant impact on the electronic properties, but it is rather challenging to control the Se/(S + Se) ratio due to a complicated selenization process. Here, a low-toxicity thiol/amine-based solution process was developed to tune the Se content in a Cu2ZnSn(S, Se)4 absorber layer to an optimal value by ingeniously controlling the SeO2 in the precursor solution. We demonstrated that the crystal growth and the band gap of Cu2ZnSn(S, Se)4 thin films are affected by the Se/(S + Se) ratio. By this approach, the open-circuit voltage deficit (Voc,def) of the device was effectively decreased, and the short-circuit density (Jsc) and fill factor (FF) were remarkably improved; thus, the power conversion efficiency of the Cu2ZnSn(S, Se)4 solar cells was successfully increased from 5.6% to 9.7% for the optimal band gap (Eg = 1.13 eV).
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2018
·
IF 11.698
Weiping Zhang,Guiying Li,Wanjun Wang,Yaxin Qin,Taicheng An,Xinyan Xiao,Wonyong Choi
A chemically modified Ag 3 PO 4 @MS 2 (M = Mo, W)/rGO composite was firstly synthesized via a liquid-exfoliation solvothermal method. The structure, morphology, optical properties and composition were characterized by X-ray diffraction, FT-IR spectroscopy, scanning electron microscopy, UV–vis diffuse reflectance spectra and X-ray photoelectron spectroscopy, respectively. The characterization results indicated that compact structure could be obtained by using this typical method due to in-situ chemical modification, which could also control the sizes of Ag 3 PO 4 nano-sheets by adding MS 2 /rGO hybrids. More importantly, the resultant Ag 3 PO 4 @MS 2 /rGO composite exhibited higher photocatalytic activity and stability toward the degradation of 4-nitrophenol than pure Ag 3 PO 4 under sunlight irradiation. The stable structure of Ag 3 PO 4 @MS 2 /rGO was closely related with Z-scheme electronic structure and electrical conductivity of MS 2 /rGO hybrids, leading to a higher consumption and transfer of photogenerated electrons. However, by controlling the amounts of MS 2 /rGO hybrids, more stable but lower photocatalytic activity composites could be obtained. Further analysis found that the holes and O 2 − were the main reactive species involved in the photocatalytic degradation of 4-nitrophenol. In addition, possible photocatalytic degradation pathways of 4-nitrophenol were also proposed based on the identified intermediates. The findings of this work may provide a new method to design efficient composites for photocatalytic degradation of organic pollutants .
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