ACTA PHYSICO-CHIMICA SINICA
·
2025
·
IF 13.5
Yanyan Zhao,Zhen Wu,Yong Zhang,Bicheng Zhu,Jianjun Zhang
Photocatalytic oxygen reduction reaction (ORR) offers a mild and cost-effective approach for hydrogen peroxide (H 2 O 2 ) production. However, its practical application is significantly hindered by rapid charge carrier recombination and insufficient O 2 adsorption capacity in photocatalysts. To address these limitations, we developed a strategy involving the creation of S-vacancy-rich CdIn 2 S 4 (S v –CIS) to facilitate charge separation and subsequent deposition of Au nanoparticles on its surface (Au–S v –CIS) to strengthen O 2 adsorption. The results suggest that the optimized Au–S v –CIS achieves a significantly increased H 2 O 2 production yield of 2542 μmol·h·g −1 in 10%-ethanol/water solution, which is about 12.8 and 1.7 times higher than that of pure CIS and S v –CIS. Comprehensive characterizations including photoluminescence spectra, time-resolved photoluminescence spectra, transient photocurrent response, electrochemical impedance spectra, and femtosecond transient absorption spectroscopy confirm the improved charge dynamics of Au–S v –CIS. In addition, temperature-programmed desorption of O 2 combined with density functional theory calculations conclusively demonstrates the superior O 2 adsorption capacity of Au–S v –CIS. This work provides a design strategy for efficient solar–to–chemical energy conversion through cooperative photocatalyst engineering.
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高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Guoliang Zhang,Cong Xue,Ruxangul Jamal,Tursun Abdiryim,Feng Xu,Qian Cheng
L-Tyrosine (L-Tyr) is one of the 21 essential amino acids for the human body. Its accurate detection is of great clinical and practical significance in monitoring, food quality and safety. Functional groups critically govern electrochemical sensor performance by mediating target adsorption. Conventional poly (3,4-ethylenedioxythiophene) (PEDOT)-based sensors face limited flexibility and active site accessibility. Amino-grafted PEDOT was developed by in situ growth on Ti 3 C 2 T X nanosheets, incorporating small-sized Au nanoparticles to create a highly conductive and active substrate for selective detection of L-Tyr. The resulting molecularly imprinted electrochemical sensor, fabricated on the PEDOT-CH 2 NH 2 /Ti 3 C 2 T X /Au NPs/GCE platform, exhibited enhanced catalytic activity and efficient L-Tyr enrichment. The combination of components improved electron transfer, MIP stability, and imprinting cavity accessibility. The sensor demonstrated a broad linear range (10 −6 –100 μM) with an ultralow detection limit (3.64 × 10 −6 μM), and exhibited excellent selectivity, reproducibility, and operational stability. Practical tests in milk matrices confirmed high recovery rates (96.65 %–101.35 %), showcasing its potential for use in complex food systems and it also has detection capabilities similar to those of standard methods. This work provides a sensitive and reliable strategy for amino acid monitoring in food, with significant applications in food safety assurance.
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ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Zheng Liu,Hong Ding,Huilun Xu,Hao Yang,Jiangshan Liu,Zhendong Zhang,Rui Xiao,Limin Liu,Ganjun Feng,Li Zhang
Eradicating the bacteria on the surface of titanium-based (Ti) implants and optimizing the local immune environment is urgently needed to minimize the clinical implantation failures. Here, an ultrasound (US)-responsive Ti implant aiming at killing bacteria is prepared by building strontium titanate (SrTiO 3 ) nanoarrays on Ti substrate through a multi-step hydrothermal method and the subsequent decoration of Au nanoparticles (Au NPs). As an n-type semiconductor, SrTiO 3 can combine with Au NPs to form a Mott–Schottky heterostructure. The results reveal that the built-in electric field of the M–S heterojunction composed of Au NPs and SrTiO 3 significantly promotes the separation of electrons and holes while reducing the bandgap. Under US irradiation, Au@SrTiO 3 generates a large amount of reactive oxygen species (ROS) to kill bacteria, meanwhile eliminating bacterial biofilms that adhere to the implant surface. Besides, Au NPs accelerate bone remodeling by modulating macrophage polarization toward inflammation-suppressive orientation. Also, SrTiO 3 and Au NPs synergistically directed the osteogenic differentiation. The implantation in vivo shows that continuously optimizing the osteogenic microenvironment can obviously accelerate the osseointegration of Ti implant. Transcriptomic analysis reveals the in vivo pro-osteointegration mechanism of heterostructured Au@SrTiO 3 nanoarrays on Ti implant.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Yayun Jiang,E Jianfei,Youwei Li,Jian Chen,Jie Yang,Yang He,Gang Mai,Laibao Zheng
Group B Streptococcus (GBS) is a major cause of neonatal morbidity and mortality, underscoring the urgent need for rapid, accurate, and deployable diagnostics. Conventional culture and nucleic acid amplification tests are limited by long turnaround time, insufficient sensitivity, or dependence on sophisticated instrumentation, restricting their use in resource-limited settings. Here, we present a magnetically controlled dual-mode biosensing platform, termed c olorimetric/ p hotothermal–CRISPR/ Cas – Au @ Pt nanozyme (CP-CasAuPt), which integrates the sequence-specific trans-cleavage activity of CRISPR/Cas12a with the peroxidase-mimicking activity of Au@PtNPs. The catalytic oxidation of 3,3′,5,5′-Tetramethylbenzidine (TMB) generates oxidized TMB (oxTMB), which provides a visible colorimetric change and a near-infrared photothermal response, thereby enabling reliable dual-mode readouts with minimal instrumentation. Magnetic bead-assisted separation further reduces background signals, ensuring robust performance in complex matrices. Using GBS as a proof-of-concept, CP-CasAuPt achieved a detection limit of 10 3 CFU/mL after loop-mediated isothermal amplification, with results fully consistent with qPCR across 20 clinical samples. Beyond high sensitivity and specificity, this study establishes a generalizable strategy for multimodal molecular diagnostics, where orthogonal dual signals allow cross-validation, ensuring robust detection across diverse assay conditions. The CP-CasAuPt system thus offers a promising paradigm for rapid, instrument-free pathogen detection, particularly suited for resource-limited settings.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Yan Zeng,Yijun Lin,Jiawei Chen,Yan Sun,Peng Qi,Peng Wang
Early detection and diagnosis are essential for effectively preventing and treating complex pathogenic bacterial infections. This study presents an innovative approach for on-site, ultrasensitive pathogen detection by integrating a uniquely designed probe binding mode with novel nanomaterial structures within a lateral flow immunoassay (LFIA) platform. Through a galvanic replacement reaction, gold is non-uniformly deposited onto a silver core, resulting in the formation of Ag@pore-Au structures. The abundant nanopores and porous surface of these structures create a high density of "hot spots", significantly enhancing their surface-enhanced Raman scattering (SERS) performance. We systematically characterized the SERS and detection capabilities of the synthesized Ag@pore-Au Raman-dye micron particles (MPs) probe. The results conclusively demonstrated that this structural probe exhibits a robust SERS signal, paving the way for its successful application in LFIA. By integrating the Ag@pore-Au Raman-dye MPs probe into the LFIA platform, we achieved rapid, quantitative detection of Escherichia coli and Staphylococcus aureus. This enhanced platform overcomes the limitations of traditional LFIA, notably its high detection limit of 10 CFU/mL and its inability to provide quantitative results. Furthermore, a dual-channel detection mode enabled the simultaneous and specific identification of both bacterial strains. The platform's efficacy was validated through successful detection in real sample matrices. This research offers novel insights and methodologies for pathogen detection in the medical field, providing an effective solution for on-site pathogen diagnosis and real-time environmental monitoring.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2025
·
IF 3.8
Song Xinyi,He Zhaoyuan,Tan Siyuan,Cong Siyu,Lu Wuli,Mai Zedeng,Jiang Mingsheng,Wen Yu,Liu Cheng,Chen Hailan
Deoxynivalenol (DON), a highly stable and globally prevalent mycotoxin, has become a critical food safety concern due to its widespread contamination in animal feed, particularly in corn, wheat, and other cereal-based ingredients. As one of the most frequently detected mycotoxins in feedstuffs, DON contamination not only causes significant economic losses in livestock production but also poses severe health risks to animals, including vomiting, immunosuppression, and growth retardation, which may ultimately affect human health through the food chain. Existing detection methods for DON are often limited by time-consuming procedures or analytical complexity. Here, we report a novel surface-enhanced Raman scattering-based lateral flow immunoassay (SERS-LFIA) for rapid, sensitive, and specific detection of DON residues in animal feeds. The biosensor employs core-shell Au@4-MBA@Ag nanoparticles functionalized with 4-mercaptobenzoic acid (4-MBA) as a Raman reporter and DON-specific antibodies for target recognition. After systematic optimization, the SERS-LFIA platform achieved both qualitative and quantitative detection within 16 min, with an exceptionally low limit of detection (LOD) of 0.01 µg/kg. The assay demonstrated excellent specificity, showing no cross-reactivity with other major mycotoxins, including aflatoxin B 1 , zearalenone, and ochratoxin A. Remarkable reproducibility was evidenced by intra- and inter-batch coefficients of variation (CV) of 3.51% and 2.19%, respectively. The test strips maintained stability for at least 3 months at 4 ± 0.5 °C and for 2 months at 25 ± 0.5 °C, making them particularly suitable for routine monitoring in feed mills and farms. This innovative SERS-LFIA system represents a significant advancement in mycotoxin detection technology, offering a robust, field-deployable solution for monitoring DON contamination in animal feed, which is crucial for ensuring feed safety and animal health. Graphical
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高影响因子
ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Lei Tian,Yuhao Zhang,Luting Yan,Qi Guo,Zekun Ren,Chao Wang,Falan Li,Qingqing Yang,Xia Sun,Yemin Guo,Yanyan Zhang
In this paper, a dual-potential-resolved label-free signal transduction electrochemiluminescence (ECL) biosensor based on hydrogen peroxide system was constructed by using CeO 2 -Au to modify the electrode, and selecting CdS QDs and DPEA-AuNCs as independent cathodic and anodic ECL light sources. CeO 2 -Au improves the conductivity and interfacial environment of the working electrode, immobilizes the DNA strand of the hairpin structure through Au-S bonding, and also catalyzes the generation of a large amount of superoxide anion from hydrogen peroxide. In order to achieve specific detection, CdS QDs and DPEA-AuNCs were selected to modify the aptamers, respectively, and two targeted functional probes were designed to recognize Staphylococcus aureus and Vibrio parahaemolyticus , respectively, and to detect these two food-borne pathogens simultaneously by two-potential discrimination. After a series of tests and validations, the sensor exhibited good selectivity and sensitivity, showcasing its significant potential in the realm of food safety detection and offering an effective method for the concurrent detection of various pathogenic bacteria in food.
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MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 9
·1-11
·
IF 6.408
Zhai Hongguo,Wang Yue,Yin Jiaqi,Zhang Yuhao,Guo Qi,Sun Xia,Guo Yemin,Yang Qingqing,Li Falan,Zhang Yanyan
MXene@Au as the base and Au@SiO 2 as signal amplification factor were used for constructing an ultrasensitive “on–off” electrochemiluminescence (ECL) biosensor for the detection of Pb 2+ in water. The use of MXene@Au composite provided a good interface environment for the loading of tris(2,2-bipyridyl)ruthenium(II) (Ru(bpy) 3 2+ ) on the electrode. Based on resonance energy transfer, the Au (core) SiO 2 (shell) (Au@SiO 2 ) nanoparticles stimulate electron transport and promote tripropylamine (TPrA) oxidation. The luminescence effect of Au@SiO 2 was five times that of AuNPs and SiO 2 nanomaterials alone, and the ECL intensity was greatly improved. In addition, Pb 2+ activated the aptamer to exert its endonuclease activity, which realized the signal cycle amplification in the process of Pb 2+ detection. When Pb 2+ was added, the ECL signal weakened, and the Pb 2+ concentration was detected according to the decreased ECL intensity. Under optimized experimental conditions, this aptamer sensor for Pb 2+ has a wide detection range (0.1 to 1 × 10 6 ng L −1 ) and a low detection limit (0.059 ng L −1 ). The relative standard deviation (RSD) of the sensor is 0.39–0.99%, and the recovery of spiked standard is between 90.00 and 125.70%. The sensor shows good selectivity and high sensitivity in actual water sample analysis. This signal amplification strategy possibly provides a new method for the detection of other heavy metal ions and small molecules. Graphical abstract
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高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Jinlong Cui,Chengui Zhang,Yalong Li,Yang Liu,Weijun Jiang,Yuhui Wen,Zhenxi Wang,Zhonghua Yu,Xiangrong Ren,Zhifu Zhang
The selective hydrogenation of cinnamaldehyde (CAL) is a key reaction for producing valuable intermediates in pharmaceuticals, fragrances, and fine chemicals. However, achieving high selectivity toward the C=O bond reduction of CAL under mild conditions remains challenging. In this study, an efficient and sustainable photocatalytic strategy for the selective transfer hydrogenation of cinnamaldehyde to cinnamyl alcohol under mild conditions was reported. The low-loading 0.5 wt% Au/TiO 2 -CeO 2 and 0.5 wt% Pt/TiO 2 -CeO 2 catalysts were prepared by sol–gel and ultraviolet deposition method. Experimental results show that heterojunction is formed by doping CeO 2 with TiO 2 . The light absorption of materials is redshifted, and the separation of photogenerated electron-hole pairs is enhanced, thereby reducing the load usage of precious metal. The 0.5 wt% Au/TiO 2 -CeO 2 catalyst exhibits optimal performance under visible light irradiation, while the 0.5 wt% Pt/TiO 2 -CeO 2 catalyst exhibits excellent activity under ultraviolet light irradiation. The conversion efficiency in 0.5 wt% Au/TiO 2 -CeO 2 catalytic system under visible light is 97.23 %, and the selectivity can reach 96.91 %. Recycling tests verified the structural stability and reusability of the prepared catalysts. The formation of heterojunction structures can effectively reduce the load of precious metal while maintaining high conversion and selectivity. These findings provide a new pathway for achieving highly selective CAL hydrogenation under mild conditions.
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CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Kezhu Xu,Jin Wu,Qunling Fang,Linfeng Bai,Jinyu Duan,Jiaxing Li,Huajian Xu,Ailing Hui,Lingyun Hao,Shouhu Xuan
The organic pollutants and heavy metal ions are critical harmful substances in waste water because they destroy the ecological systems and lead diseases to animals and human beings. Unfortunately, the simultaneously remove of them in one system is still a challenge due to their different treating mechanism. Herein, a novel magnetic h-Fe 3 O 4 @Au/Polydopamine (Au/PDA) hybrid hollow nanosphere which can both absorb the potentially toxic U(VI) ions and catalyze the reduction of the 4-nitrophenol is reported. By using a simple in situ redox-oxidizing polymerization method, the h-Fe 3 O 4 hollow nanosphere is well encapsulated by the Au/PDA hybrid shell to form the dual-functional magnetic hollow nanocomposites. Owing to the hollow interior, uniform and functional PDA coating, and high active Au nanocrystals, the final h-Fe 3 O 4 @Au/PDA hollow nanosphere possesses high potential in nanocatalysis, heavy metal ions adsorption, and drug delivery. Because of the PDA protection, the h-Fe 3 O 4 @Au/PDA nanosphere can even keep 90% activity after 7 cycling catalytic reactions on reduction of 4-nitrophenol. Similarly, the h-Fe 3 O 4 @Au/PDA exhibits a good adsorption effect for U(VI) in nuclear waste and its adsorption capability reaches to 82.9 mg·g −1 by 6 successive adsorption–desorption experiments. Due to the facile magnetic separation, the h-Fe 3 O 4 @Au/PDA nanosphere can be easily collected by applying an external magnetic field. In summary, such a multifunctional recyclable h-Fe 3 O 4 @Au/PDA nanosphere with green and facile synthesis, easy manipulation, efficient adsorption performance and good catalytic activity possesses broad application potential in treatment of coexisting toxic water pollution.
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CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Shiyu Zhang,Aiguo Rao,Kai Lin,Qi Yao,Chunhui Niu,Lei Wang,Mingqing Yang,Xueqiong Bai,Yong Lv
Recently, the Fabry–Perot (F–P) cavity electrochromic devices, which are constructed by combining nano-size inorganic electrochromic material WO 3 and reflective metal layers, have attracted considerable attention due to their potentials in the fields of dynamic multicolor displays and active camouflage. However, in the few studies that have been reported, the peak reflectance of flexible F–P cavity multicolor electrochromic devices in the visible wavelength band is generally lower than 30 %, which limits their reflective display and camouflage effects in high-brightness environments. Thus, we have combined multicolor reflective electrochromic electrodes in WO 3 /Au asymmetric F–P nanocavity constructed by magnetron sputtering on a Nylon 66 porous substrate with a highly transparent UV-cured gel electrolyte and a PET plastic sealing procedure. As a result, a flexible and dynamic multicolor electrochromic skin with high reflectance (R max ＞50 %) and excellent flexibility (bending radius of 4 mm) has been fabricated. The WO 3 electrochromic layer at the top works as the dynamic dielectric layer in the broadband absorption Fabry–Perot cavity, and the inert metal Au layer at the bottom works as the reflective layer. The WO 3 /Au asymmetric F–P cavity can acutely capture the variation in optical constants of WO 3 due to the thickness change and electric-driven effects. This cavity facilitates the selective reflection and absorption of the energy distribution of the spectrum after the induced interferometric resonance. As a result, the cavity exhibits a rich array of structural colors, including ocher, taupe, yellow, orange, green, and violet. The electrochromic skin exhibits a fast switching time and maintains 99.43 % of the optical modulation amplitude (ΔR) after 110 coloring/bleaching cycles. It provides a potential option in the field of flexible high-brightness reflective displays and dynamic camouflage in the future.
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APPLIED CATALYSIS A-GENERAL
·
2024
·
IF 4.7
Chenyang Zhao,Yujia Liu,Yupeng Tian,Yahui Li,Junjie Feng,Wei Xu,Ning Shi,Zhe Yang,Bing Sun
Direct epoxidation of propylene (C 3 H 6 ) with hydrogen (H 2 ) and oxygen (O 2 ) over Au/TS-1 catalyst was promising way for the synthesis of propylene oxide (PO). However, high selectivity of PO (>95 %) and conversion of C 3 H 6 (>5 %) cannot be achieved at the same time. The industrialization process was severely restricted. In this paper, Au/TS-1 catalysts were synthesized by deposition precipitation method with alkali metal promoter. And alkaline gases and silane coupling post-treatment were performed to promote the catalytic activity. The prepared samples exhibited a much better C 3 H 6 conversion (6.5 %) and PO selectivity (95.1 %) compared with general catalyst using normal synthetic technology. Cs 2 CO 3 was beneficial to increasing Au nanoparticles uptake efficiency. Both NH 3 and triethoxyvinylsilane post-treatment were good for smaller and more uniform loading of Au nanoparticles. The decreasing in surface hydroxyl density effectively alleviated the occurrence of PO ring opening isomerization. The increased hydrophobicity of TS-1 surface was conducive to the rapid desorption of generated PO and significantly increased PO selectivity. Multiple pretreatment was also favorable for extending the lifetime of Au/TS-1 catalyst.
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危险品化学品经营许可证（带存储）