Frontiers of Environmental Science & Engineering
·
2018
·Vol. 12
·期 4
·1-11
·
IF 1.961
Wang Xiangyu,Lian Weitao,Sun Xin,Ma Jun,Ning Ping
Polydopamine/NZVI@biochar composite (PDA/NZVI@BC) with high removal efficiency of tetracycline (TC) in aqueous solutions was successfully synthesized. The resultant composite demonstrated high reactivity, excellent stability and reusability over the reaction course. Such excellent performance can be attributed to the presence of the huge surface area on biochar (BC), which could enhance NZVI dispersion and prolong its longevity. The carbonyl group contained on the surface of biochar could combine with the amino group on polydopamine(PDA). The hydroxyl groups in PDA is able to enhance the dispersion and loading of NZVI on BC. Being modified by PDA, the hydrophilicity of biochar was improved. Among BC, pristine NZVI and PDA/NZVI@BC, PDA/ NZVI@BC exhibited the highest activity for removal of TC. Compared with NZVI, the removal efficiency of TC could be increased by 55.9% by using PDA/NZVI@BC under the same conditions. The optimal modification time of PDA was 8h, and the ratio of NZVI to BC was 1:2. In addition, the possible degradation mechanism of TC was proposed, which was based on the analysis of degraded products by LC-MS. Different important factors impacting on TC removal (including mass ratio of NZVI to BC/PDA, initial concentration, pH value and the initial temperature of the solution) were investigated as well. Overall, this study provides a promising alternative material and environmental pollution management option for antibiotic wastewater treatment.
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Journal of Materials Chemistry C
·
2022
·Vol. 10
·期 46
·17512-17520
·
IF 8.067
Jizhong Liu,Hui Fu,Zhentao Du,Deliu Ou,Shixian Li,Qiaochu Chen,Weiyou Yang,Jialong Zhao,Jinju Zheng
The photothermal stability against light irradiation and high temperature of organic–inorganic hybrid perovskite nanocrystals (PNCs) is critically important for their applications in photoelectronic nanodevices. In the present work, we report the significantly enhanced photothermal stability of FAPbBr3 PNCs, which are fabricated by in situ growth of PNCs in polyvinylidene fluoride films (FAPbBr3@PVDF) with incorporation of Cd2+ ions. It is found that the introduced Cd2+ ions could effectively passivate the PNC defects and shorten the length of Pb–Br bonds, giving rise to the intensified interaction between Pb2+ and Br− in the [PbBr6]4− octahedron, which thereby suppresses the halogen ion migration under light irradiation and high temperature with enhanced photothermal stability. As a result, the Cd2+-doped FAPbBr3@PVDF film exhibits durable photothermal stability with 96% and 97% photoluminescence quantum yield (PLQY) retentions, under continuous blue-light irradiation (460 nm, 13 mW cm−2) for over 360 h, and under both a high temperature of 333 K and blue-light irradiation over 48 h, respectively. Furthermore, the as-constructed white light-emitting-diodes (WLEDs) deliver a wide color gamut (117% of NTSC standard) with chromaticity coordinates of (0.331, 0.337), verifying their promising applications in backlight sources.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2021
·Vol. 33
·期 1
·458-467
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IF 2.478
Dong Hua-Dong,Zhao Jian-Ping,Peng Ming-Xing,Zhang Yong-Hui
The Schottky barrier at the interface between the semiconductor phase and the metal phase has excellent rectification effect which can greatly facilitate the formation of the electron accumulation region. The interface electronic modulation can promote the formation of electron depletion layer in the gas sensing process, which is a powerful strategy to improve the sensing performance. In this work, ZnO–TiC composites were successfully prepared. XRD, TEM, BET and XPS characterizations of the ZnO–TiC composites were proformed to investigate the compositions and structures. The as-synthesized samples were applied to fabricate gas sensors to investigate their gas sensing performance. Compared to pure ZnO and TiC, the composites achieved high sensitivity (232 for 100 ppm aniline) and linear detection ( R 2 = 0.986) of aniline. The improvement of sensor performance is mainly attributed to the electronic modulation of Schottky barrier at the interface between ZnO and TiC. Our results indicate that the construction of ZnO-TiC Schottky barrier is a promising strategy for enhancing the performance of gas sensors.
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JOURNAL OF HAZARDOUS MATERIALS
·
2021
·
IF 10.588
Shunli Wan,Yan Li,Shuo Cheng,Guowei Wu,Xuan Yang,Yu Wang,Liangmin Gao
Metallic oxide nanoparticles (NPs) anchored in biochar provide a promising measure forward into the scaled-up application of these NPs in water treatment , and reducing the size of the dwelled NPs is expected to boost the adsorption performance of biochar-based composites because of the size and surface effect. Nevertheless, it is still of great challenge to regulate the size of the impregnated NPs due to their intrinsic self-agglomeration caused by high surface energy . In this study, we fabricated the charged biochar (C-BC) bearing high-density negatively charged groups (i.e., carboxyl and hydroxyl groups) via HNO 3 oxidization to load the model metal oxide FeOOH NPs. The average sizes of anchored FeOOH NPs were ultrasmall, ranging from 19.9 ± 1.5 to 3.1 ± 0.5 nm, and decreased with the increased amount of carboxyl and hydroxyl groups in C-BC. Whether in batch adsorption or fixed-bed column setting, adsorption of Cd(II) onto the as-made composites was greatly enhanced by carboxyl and hydroxyl groups in carrier. The normalized adsorption capacities of Cd(II) by ferric mass of the loaded FeOOH were 499.9–724.9 mg/g-Fe, approximately 18.6–27.1 and 2.51–3.64 folds over the bulky FeOOH and FeOOH-impregnated biochar. Our study results should provide a significant reference on how to acquire highly efficient biochar-based composites for water decontamination .
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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
·
2014
·Vol. 34
·期 5
·1780-1791
·
IF 3.55
Zhang Rong,Xiang Yang,Ran Qian,Deng Xiaojun,Xiao Yanni,Xiang Lixin,Li Zhongjun
Aim: The aim of this study was to investigate the mechanisms of Cr6+-induced red blood cells (RBCs) damage. Methods: The effect of Cr6+ exposure on RBCs was evaluated by hemolytic rate and blood gas assays. After exposure to 20 μM Cr6+, the percentage of phosphatidylserine (PS)-exposing cells, intracellular Ca2+, reactive oxygen species (ROS), and ATP levels were evaluated, and cell morphology was observed. RBCs were exposed to Cr6+ in different Ringer solutions to investigate the role of changes of Ca2+, ROS, and ATP levels in eryptosis and morphology. Results: The Cr6+-induced damage of RBCs was dose-dependent. After a 6 h incubation with Cr6+, RBCs exhibited significant Ca2+ influx, ROS increase, ATP depletion, and PS exposure, but displayed no obvious change in morphology at this time point. After 24 h Cr6+ exposure, the RBCs decreased in size, appeared to be spike-like, and had decreased forward scatter. Inhibition of Ca2+ influx attenuated PS-exposure caused by 6 h Cr6+ exposure, but did not prevent 24 h Cr6+ exposure-induced morphological change in RBCs. Inhibition of rapid ATP consumption using adenine significantly ameliorated Cr6+-caused PS-exposure at 12 h, 24 h and 48 h, and prevented 24 h Cr6+ incubation-induced morphological change in RBCs. Conclusion: Cr6+ can lead to eryptosis. Ca2+ influx, increased ROS levels, and rapid ATP consumption are closely related to Cr6+-induced RBCs damage. Ca2+ influx plays an extremely important role in Cr6+-mediated toxicity
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Scientific Reports
·
2017
·Vol. 7
·期 1
·1-9
·
IF 4.259
Ke Shanming,Li Tao,Ye Mao,Lin Peng,Yuan Wenxiang,Zeng Xierong,Chen Lang,Huang Haitao
(In + Nb) co-doped TiO 2 (TINO) rutile is an emerging material with a colossal dielectric permittivity (CP) and a low dielectric loss over wide temperature and frequency ranges. The electrical inhomogeneous nature of TINO ceramics is demonstrated by direct local current probing with high-resolution conductive atomic force microscopy (cAFM). The CP response in TINO is found to originate from the electron-pinned defect dipole induced conductive cluster effect and the electrode effect. Two types of dielectric relaxations are simultaneously observed due to these two effects. With the given synthesis condition, we found TINO shows a highly leaky feature that impairs its application as a dielectric material. However, the fast-temperature-rising phenomenon found in this work may open a new door for TINO to be applied as a potential electrothermal material with high efficiency, oxidation-proof, high temperature stability, and energy saving.
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Food Science and Technology
·
2022
·
IF 2.602
ZENG Guibing,TIAN Wenran,ZENG Zheling,YAN Xianghui,YU Ping,GONG Deming,WANG Jun
The infants who cannot be breastfeed need to obtain energy and nutrition from other sources, such as formula. In this study, a human milk fat substitute (HMFS) rich in structured triglycerides (STG) and with a variety of fatty acids was prepared by one-step transesterification reaction. The optimum conditions for the lipase-catalyzed transesterification between basa catfish oil solid fraction, Cinnamomum camphora seed kernel oil, linseed oil, microbial oil and algae oil were studied and the in vitro digestibility of the constructed HMFS was investigated. Under the optimal conditions, the obtained HMFS contained 58.86% STG and 39.73% sn-2 palmitic acid (PA). Fatty acid composition analysis showed that HMFS was composed of capric acid (Ca), lauric acid (La), oleic acid (O), linoleic acid (L), linolenic acid (Ln), arachidonic acid (ARA) and docosahexaenoic acid (DHA). LC-MS/MS analysis found that 142 new triglycerides were generated, such as Ca-P-ARA, Ca-P-Ln, La-P-ARA, La-P-L and P-O-ARA. Moreover, compared with physical mixture (PM), HMFS had better melting and crystallization temperature and the fatty acid release rate of HMFS was significantly improved. These results suggested that HMFS may have a great application in infant food as a nutritional ingredient.
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Nature Communications
·
2017
·Vol. 8
·期 1
·1-12
·
IF 12.124
Su Jianwei,Yang Yang,Xia Guoliang,Chen Jitang,Jiang Peng,Chen Qianwang
The scalable production of hydrogen could conveniently be realized by alkaline water electrolysis. Currently, the major challenge confronting hydrogen evolution reaction (HER) is lacking inexpensive alternatives to platinum-based electrocatalysts. Here we report a high-efficient and stable electrocatalyst composed of ruthenium and cobalt bimetallic nanoalloy encapsulated in nitrogen-doped graphene layers. The catalysts display remarkable performance with low overpotentials of only 28 and 218 mV at 10 and 100 mA cm −2 , respectively, and excellent stability of 10,000 cycles. Ruthenium is the cheapest platinum-group metal and its amount in the catalyst is only 3.58 wt.%, showing the catalyst high activity at a very competitive price. Density functional theory calculations reveal that the introduction of ruthenium atoms into cobalt core can improve the efficiency of electron transfer from alloy core to graphene shell, beneficial for enhancing carbon–hydrogen bond, thereby lowing ΔG H* of HER.
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Frontiers in Plant Science
·
2022
·
IF 6.627
Li Ling,Yan Xuyu,Li Juan,Wu Xiang,Wang Xiukang
Cadmium (Cd), a non-essential element for plant, is a ubiquitous and highly toxic heavy metal, seriously endangering agricultural production and human health. As a nonedible economic crop, cotton (Gossypium hirsutum L.) has great potential in remediation of Cd contaminated soil, but its underlying mechanism is still unknown. Melatonin (MT), as a plant growth regulator, is involved in alleviating Cd toxicity in some plants, but the molecular mechanisms of MT-mediated Cd detoxification in cotton are largely unknown. This study investigated the possible molecular mechanisms of the MT-mediated Cd detoxification in cotton seedlings by comparative transcriptomic and metabolomic analyses. The results showed that the cotton seedlings were dwarfed and the leaves were wilted and yellow under Cd stress. The application of 50 µmol L−1 MT significantly increased the superoxide dismutase (SOD) activity and malondialdehyde (MDA) content under Cd stress, but 100 µmol L−1 MT significantly decreased SOD activity, while increased ascorbate peroxidase (APX) activity significantly. The addition of 100 μmol L−1 MT significantly increased Cd concentration in the shoots and roots under Cd stress. RNA-seq analysis showed that 5573, 7105, 7253, 25, 198, 9 up-regulated and 6644, 7192, 7404, 9, 59, 0 down-regulated differentially expressed genes (DEGs) were identified in the comparisons of CK vs T1, CK vs T2, CK vs T3, T1 vs T2, T1 vs T3 and T2 vs T3, respectively. It was revealed that MT promoted the expression of certain related genes under Cd stress, and the effect of 100 µmol L−1 MT was better. Moreover, UPLC-MS/MS widely targeted metabolites analyses showed that 195, 150, 150, 12, 24, 59 up-regulated and 16, 11, 23, 38, 127, 66 down-regulated differentially accumulated metabolites (DAMs) were changed in the CK vs T1, CK vs T2, CK vs T3, T1 vs T2, T1 vs T3 and T2 vs T3, respectively. It was revealed that MT induced the synthesis of alkaloids and flavonoids, and inhibited or reduced the synthesis of lipids, amino acids and their derivatives. The comprehensive analyses of transcriptomic and metabolic data showed that 33 DEGs and 4 DAMs, 46 DEGs and 16 DAMs, and 1 DEGs and 1 DAMs were dominantly involved in the pathways of valine, leucine and isoleucine degradation, ABC transporter, alpha-linolenic acid metabolism, respectively. It was revealed that there were three major mechanisms involved in MT-mediated Cd detoxification in cotton, including the enhancement of antioxidant capacity regulated by APX, flavonoids and alkaloids; accumulation of secondary metabolites related to Cd chelation, such as amino acids and derivatives; and regulation of cadmium ion transportation, such as ABC transporter activation. In conclusion, this study provides new insights into the MT-mediated Cd stress response.
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Small
·
2020
·Vol. 16
·期 37
·2002748
·
IF 11.459
Kai Cai,Weiyun Zhang,Mohamed F. Foda,Xuyu Li,Jin Zhang,Yeteng Zhong,Huageng Liang,Huiqiao Li,Heyou Han,Tianyou Zhai
The miniaturization of gold nanorods exhibits a bright prospect for intravital photoacoustic imaging (PAI) and the hollow structure possesses a better plasmonic property. Herein, miniature hollow gold nanorods (M-AuHNRs) (≈46 nm in length) possessing strong plasmonic absorbance in the second near-infrared (NIR-II) window (1000–1350 nm) are developed, which are considered as the most suitable range for the intravital PAI. The as-prepared M-AuHNRs exhibit 3.5 times stronger photoacoustic signal intensity than the large hollow Au nanorods (≈105 nm in length) at 0.2 optical density under 1064 nm laser irradiation. The in vivo biodistribution measurement shows that the accumulation in tumor of miniature nanorods is twofold as high as that of the large counterpart. After modifying with a tumor-targeting molecule and fluorochrome, in living tumor-bearing mice, the M-AuHNRs group gives a high fluorescence intensity in tumors, which is 3.6-fold that of the large ones with the same functionalization. Moreover, in the intravital PAI of living tumor-bearing mice, the M-AuHNRs generate longer-lasting and stronger photoacoustic signal than the large counterpart in the NIR-II window. Overall, this study presents the fabrication of M-AuHNRs as a promising contrast agent for intravital PAI.
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ENVIRONMENTAL HEALTH PERSPECTIVES
·
2022
·
IF 11.035
Lilong Jiang,Yanjun Hong,Pingting Xiao,Xiaoxiao Wang,Jinghui Zhang,Ehu Liu,Huijun Li,Zongwei Cai
Background: Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant that can cause hepatotoxicity. The underlying toxicological mechanism remains to be investigated. Given the critical role of fecal microbiota in liver function, it is possible that fecal microbiota may contribute to the liver toxicity induced by PFOS. Objectives: We aimed to investigate the role of liver-fecal microbiota axis in modulating PFOS-induced liver injury in mice. Methods: Male and female mice were exposed to PFOS or vehicle for 14 d. In this investigation, 16S rDNA sequencing and metabolomic profiling were performed to identify the perturbed fecal microbiota and altered metabolites with PFOS exposure. In addition, antibiotic treatment, fecal microbiota transplantation, and bacterial administration were conducted to validate the causal role of fecal microbiota in mediating PFOS-induced liver injury and explore the potential underlying mechanisms. Results: Both male and female mice exposed to PFOS exhibited liver inflammation and steatosis, which were accompanied by fecal microbiota dysbiosis and the disturbance of amino acid metabolism in comparison with control groups. The hepatic lesions were fecal microbiota-dependent, as supported by antibiotic treatment and fecal microbiota transplantation. Mice with altered fecal microbiota in antibiotic treatment or fecal microbiota transplantation experiments exhibited altered arginine concentrations in the liver and feces. Notably, we observed sex-specific lower levels of key microbiota, including Lactobacillus , Enterococcus , and Akkermansia . Mice treated with specific bacteria showed lower arginine levels and lower expression of the phosphorylated mTOR and P70S6K, suggesting lower activity of the related pathway and mitigation of the pathological differences observed in PFOS-exposed mice. Conclusions: Our study demonstrated the critical role of the fecal microbiota in PFOS-induced liver injury in mice. We also identified several critical bacteria that could protect against liver injury induced by PFOS in male and female mice. Our present research provided novel insights into the mechanism of PFOS-induced liver injury in mice. https://doi.org/10.1289/EHP10281
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2019
·Vol. 20
·期 8
·1966
·
IF 4.183
Yujuan Zhang,Li Guo,Jinhu Huang,Yong Sun,Fang He,Mire Zloh,Liping Wang
Overcoming P-glycoprotein (P-gp) efflux is a strategy to improve the absorption and pharmacokinetics of its substrate drugs. Berberine inhibits P-gp and thereby increases the bioavailability of the P-gp substrate digoxin in rodents. However, the effects of berberine on P-gp in chickens are still unclear. Here, we studied the role of berberine in modulating broilers P-gp expression and function through both in situ and in vitro models. In addition, molecular docking was applied to analyze the interactions of berberine with P-gp as well as with chicken xenobiotic receptor (CXR). The results showed that the mRNA expression levels of chicken P-gp and CXR decreased in the ileum following exposure to berberine. The absorption rate constant of rhodamine 123 increased after berberine treatment, as detected using an in situ single-pass intestinal perfusion model. Efflux ratios of P-gp substrates (tilmicosin, ciprofloxacin, clindamycin, ampicillin, and enrofloxacin) decreased and the apparent permeability coefficients increased after co-incubation with berberine in MDCK-chAbcb1 cell models. Bidirectional assay results showed that berberine could be transported by chicken P-gp with a transport ratio of 4.20, and this was attenuated by verapamil (an inhibitor of P-gp), which resulted in a ratio of 1.13. Molecular docking revealed that berberine could form favorable interactions with the binding pockets of both CXR and P-gp, with docking scores of −7.8 and −9.5 kcal/mol, respectively. These results indicate that berberine is a substrate of chicken P-gp and down-regulates P-gp expression in chicken tissues, thereby increasing the absorption of P-gp substrates. Our findings suggest that berberine increases the bioavailability of other drugs and that drug-drug interactions should be considered when it is co-administered with other P-gp substrates with narrow therapeutic windows.Keywords:berberine;P-glycoprotein;inhibition;MDCK-chAbcb1 cell line;chicken
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