Catalysis Science & Technology
·
2013
·Vol. 3
·期 10
·2620-2626
·
IF 3.753
Chunhui Chen,Ensheng Zhan,Na Ta,Yong Li,Wenjie Shen
Pd nanocubes of 6–19 nm in size were synthesized using a seeded growth method and examined for enantioselective hydrogenation of α,β-unsaturated carboxylic acids. It was found that the Pd nanocubes had two types of active sites on the planes and at the edges, respectively. Small nanocubes having a higher edge/plane ratio were more active in enantioselective hydrogenation of α,β-unsaturated carboxylic acids, but afforded a lower enantioselectivity because their sharp edges could not offer stable adsorption of the chiral modifier and the reaction intermediates. In contrast, large nanocubes with a higher fraction of flat planes provided a higher enantioselectivity but a much lower activity.
研究领域:
化学
·
纳米材料科学
·
催化反应
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2016
·
IF 4.758
Huanshun Yin,Zhiqing Yang,Haiyan Wang,Yunlei Zhou,Shiyun Ai
A simple and sensitive electrochemical biosensor was fabricated for hydroxymethylated DNA detection and T4 β-glucosyltransferase activity assay based on the glycosylation of hydroxymethylated DNA and Hpa II restriction endonuclease system triggering signal amplification. After immobilizing double-stranded DNA (dsDNA) on the surface of carboxyl functionalized Fe 3 O 4 nanoparticle, the glycosylation reaction of hydroxymethylated cytosine can be performed with the catalytic effect of T4 β-glucosyltransferase using uridine diphosphoglucose as glucose donor. Then, 4-mercaptophenylboronic acid (4-MPBA) can be further reacted with glucose and captured on Fe 3 O 4 nanoparticle surface. After the dsDNA was digested by Hpa II, the fragment with 4-MPBA can be released from Fe 3 O 4 nanoparticle surface. After magnetic separation, this fragment can be further modified on gold electrode surface through the interaction between Au and −SH, which can result in a decreased electrochemical signal of [Fe(CN) 6 ] 3− . According to this detection strategy, the electrochemical biosensor showed high sensitivity with the low detection limits of 0.14 nM and 0.27 unit/mL for hydroxymethylated DNA and T4 β-glucosyltransferase. The fabricated biosensor also presented high selectivity and acceptable reproducibility. In addition, the inhibition activity of 4-phenylimidazole towards T4 β-glucosyltransferase was also investigated. This work provides a novel platform for hydroxymethylated DNA detection, T4 β-glucosyltransferase activity assay and its inhibition screening.
研究领域:
生物化学
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分子生物学
·
分析化学
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DOI
高影响因子
Journal of Chemistry
·
2024
·Vol. 2024
·期 1
·7650883
·
IF 2.8
Yingjie Fu,Hui Xi,Dingzhong Wang,Wenqian Sun,Jiaming Zhao,Peng Li,Binbin Lu,Shitong Zeng,Qingzhao Shi,Weichen Zhang,Shihao Sun
Competitive release is an important release pattern of β-cyclodextrin (β-CD) inclusion complexes. Releasing flavor by absorbing harmful molecules is an ideal situation. Thus, two inclusion complexes, phenethyl alcohol β-CD inclusion (PACD) and phenol β-CD inclusion (PNCD), were prepared and their combining capacity was studied. The binding constant of PNCD was over 9 times more than PACD. PN could accelerate the release of PACD by entering the empty β-CD, revealing competitive release effect. However, we noticed that weak-combining molecules also induced competitive release effect. PACD and PNCD were treated with several different competitors, demonstrating that the release behavior of β-CD inclusion complexes could be controlled by changing competitors. However, the process lasted much longer for “weak” molecules to exchange “strong” ones. The mechanism of competitive release of β-CD inclusion complexes was conforming to chemical equilibrium theory. The release rate could be adjusted by changing the competitors with different concentration and different combining capacity. Moreover, solid inclusion complexes could interact with gaseous competitors, revealing competitive release effect. Competitive release effect could achieve the release of flavor while absorbing harmful molecules. Also, combining capacity or solvent condition was not the determination of competitive release effect, but also an adjustment strategy for molecule release, largely expanding the application of β-CD inclusion complexes.
研究领域:
食品科学
·
化学
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Qingxia Kuang,Shouhua Feng,Ming Yang
Aramid nanofibers (ANFs), with attractive mechanical and thermal properties, have attracted much attention as key building units for the design of high-performance composite materials. Although great progress has been made, the potential of ANFs as fibrous protein mimetics for controlling the growth of inorganic materials has not been fully revealed, which is critical for avoiding phase separation associated with typical solution blending. In this work, we show that ANFs could template the oriented growth of β-FeOOH nanowhiskers, which enables the synthesis of ANFs/β-FeOOH hybrids as composite coatings for polypropylene (PP) separators in Li–S batteries. The modified PP separator exhibits enhanced mechanical properties, heightened thermal performance, optimized electrolyte wettability, and improved ion conductivity, leading to superior electrochemical properties, including high initial specific capacity, better rate capability, and long cycling stability, which are superior to those of the commercial PP separators. Importantly, the addition of β-FeOOH to ANFs could further contribute to the suppression of lithium polysulfide shuttling by chemical immobilization, inhibition of the growth of lithium dendrites because of the intrinsic high modulus and hardness, and promotion of reaction dynamics due to the catalytic effect. We believe that our work may provide a potent biomimetic pathway for the development of advanced battery separators based on ANFs.
研究领域:
材料科学
·
能源存储
·
仿生学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIORESOURCE TECHNOLOGY
·
2015
·
IF 4.494
Hong Guo,Shaolan Zou,Boshi Liu,Rongxin Su,Renliang Huang,Wei Qi,Minhua Zhang,Zhimin He
Enzyme recycling by re-adsorption is one of the primary methods for reducing enzyme usage in lignocellulose conversion. This work proposes the combination of an engineered yeast strain that expresses β-glucosidase with enzyme recycling to reduce the amount of supplemented β-glucosidase in enzyme recycling experiments. Using the engineered strain, a slight increase in ethanol concentration was obtained after a 96-h fermentation of pretreated corncobs. Ethanol concentrations increased by 34.7% and 62.7% in the following two recycle rounds using the engineered strain compared with those using its parental strain without β-glucosidase addition. Furthermore, with the addition of β-glucosidase at 30 CBU/g cellulose, the ethanol concentration after two recycle rounds exceeded 90% of that observed in the first SSF round with the engineered strain at a high initial cellulase loading of 45 FPU/g cellulose.
研究领域:
生物技术
·
酶工程
·
发酵工程
✓ 已验证
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2016
·
IF 2.758
Huan Zhou,Saisai Hou,Mingjie Zhang,Hong Chai,Yang Liu,Sarit B Bhaduri,Lei Yang,Linhong Deng
Biphasic calcium phosphate (BCP) compositions consisting of β-tricalcium phosphate (β-TCP) and calcium pyrophosphate (CPP) are potential biodegradable ceramics for bone regeneration. The present work demonstrates the formation of such dense ceramics by first preparing the precursors of nano-sized, amorphous , and equiaxed calcium pyrophosphate particles, and then sintering the precursors at 900 °C to transform them into desired BCP. However, if the complex of calcium tripolyphosphate was used, only CPP could be generated. It was also observed that the incorporation of Mg 2+ had several effects on the resulting products including: (1) promoting the generation of meso-porous precipitates; (2) favoring the formation of β-TCP instead of CPP; (3) reducing the grain size and increasing the density of the sintered ceramics, and (4) enhancing the negative electric charge of the BCP surface. Thus, the as-prepared BCP ceramics can serve as potential bone substitute materials in orthopedic applications.
研究领域:
材料科学
·
生物医学工程
·
骨科
✓ 已验证
DOI
高影响因子
CHINESE CHEMICAL LETTERS
·
2012
·
IF 0.978
Guo Wen Chen,Chen Zhang,Wen Jie Li,Chuan Jian Zhou,Sheng Yu Feng
A new β -cyclodextrin modified hyperbranched carbosilane stationary phase for gas chromatography was synthesized by substituting the OH groups of β -cyclodextrin with hyperbranched carbosilane and was coated on the inner wall of fused silica capillary column for gas chromatography. The chromatographic behaviors of the stationary phase were studied. The initial testing results showed that it possessed good separation abilities for several kinds of mixtures, such as benzenes, acrylates , ketones and alkylchlorides.
研究领域:
分析化学
·
材料科学
✓ 已验证
DOI
高影响因子
Green Chemical Engineering
·
2020
·
IF 0
Yongqiang Zhang,Yingying Cao,Xiangzhan Meng,Phonphat Prawang,Hui Wang
A process for extraction of artemisinin (Ars) from Artemisia annua L. based on aqueous solution of cyclodextrin derivative under ultrasonic irradiation was proposed. Among the test additives, the system containing edible hydroxypropyl-β-cyclodextrin (HPBCD) was shown to be efficient for this extraction. The optimal extraction conditions were predicted by artificial neural network, under which the extraction amount of Ars could reach 8.66 mg per gram of the leaves, much higher than the value in water (1.70 mg g -1 ). Kinetics study indicated that HPBCD enhanced the equilibrium amount of Ars in water, and ultrasonic irradiation accelerated extraction rate and reduced the activation energy. Mechanism study showed that the formation of Ars-HPBCD complex during extraction enhanced the water solubility of Ars and facilitated the extraction, and the configuration of Ars-HPBCD complex was modeled by molecular docking, which was further verified by characterizations. This work provides a convenient way to fabricate the traditional tea-based medicament of natural drugs to make production of this famous antimalarial medicine cheaper.
研究领域:
药学
·
植物化学
✓ 已验证
DOI
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Lifan Cai,Jingjing Yang,Tuo Zhao,Jijun Huang,Zequn Li,Hao Zhang,Yiwen Yao,Wanxin Zhu,Xinming Wu,Le Shao
With the advancement of the global dual-carbon goal, green technology has become a priority in the energy field. Among energy storage technologies, all-solid-state batteries attract significant attention due to their high energy density, enhanced safety, and long cycle life. Poly(ethylene oxide) (PEO)-based polymer solid-state electrolytes are a research hotspot for next-generation lithium-metal batteries because of their flexibility, film-forming capabilities, and compatibility with lithium salts. In this study, cyclodextrin (β-CD) is employed as a green filler and combined with high-modulus polyacrylonitrile (PAN) fibers and plastic crystalline succinonitrile (SN) to synergistically enhance the electrochemical and mechanical properties of PEO-based electrolytes. The PAN/PEO/LiClO 4 /β-CD/SN electrolyte achieves an ionic conductivity of 6.5 × 10 −5 S cm −1 at 30°C and a lithium ion transference number of 0.33 at 80°C. PAN fiber significantly improves mechanical properties, achieving a tensile strength exceeding eight times that of the PEO/LiClO 4 membrane. In Li/Li symmetric batteries, the electrolyte demonstrates excellent interfacial stability for over 1100 h at 0.1 mA cm −2 . Additionally, the LiFePO 4 |PAN/PEO/LiClO 4 /β-CD/SN|Li coin cell exhibits an initial discharge specific capacity of 148 mAh g −1 at 80°C and 0.5C, retaining 70% capacity after 200 cycles. This study presents a novel design approach for utilizing green fillers in SPEs.
研究领域:
材料科学
·
能源技术
·
绿色化学
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产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2025
·
IF 2.5
Sisi Zhang,Weiping Liu,Sikai Wang,Lei Wang,Lin Lv,Yan Zhao
β-Galactosidase (β-Gal), alternatively referred to as lactase, is intricately associated with cellular aging and the progression of ovarian and breast cancers due to its aberrant activity. Therefore, the accurate detection of this enzyme holds substantial importance for early disease diagnosis. In this work, a sensitive ratiometric fluorescent sensing system utilizing silver nanoclusters (AgNCs) was developed for the first time to measure β-Gal activity. Specifically, β-Gal catalyzed the hydrolysis of its substrate 3-indoxyl-β-D-galactopyranoside, leading to the production of hydrogen peroxide (H2O2) and an indoxyl oxidation product that emitted blue fluorescence at 478 nm. The generated H2O2 effectively quenched the fluorescence of AgNCs at 627 nm. Thus, the fluorescence intensity ratio F478/F627 can be used for the detection of β-Gal activity. The results demonstrated that the ratio of F478/F627 exhibited excellent linear correlations with β-Gal activity within the ranges of 0.2-10.0 U/L and 10.0-50.0 U/L, achieving a detection limit of 0.031 U/L. Furthermore, the ratiometric fluorescent method was effectively utilized to measure β-Gal levels in human serum samples, highlighting its substantial potential for clinical diagnostics.
研究领域:
生物化学
·
医学诊断
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2022
·Vol. 18
·期 14
·2107490
·
IF 15.153
Huiyu Nong,Qinke Wu,Junyang Tan,Yujie Sun,Rongxu Zheng,Rongjie Zhang,Shilong Zhao,Bilu Liu
In recent years, 2D layered semiconductors have received much attention for their potential in next-generation electronics and optoelectronics. Wide-bandgap 2D semiconductors are especially important in the blue and ultraviolet wavelength region, although there are very few 2D materials in this region. Here, monolayer β-type zirconium nitride chloride (β-ZrNCl) is isolated for the first time, which is an air-stable layered material with a bandgap of ≈3.0 eV in bulk. Systematical investigation of layer-dependent Raman scattering of ZrNCl from monolayer, bilayer, to bulk reveals a blueshift of its out-of-plane A 1g peak at ≈189 cm –1 . Importantly, this A 1g peak is absent in the monolayer, suggesting that it is a fingerprint to quickly identify the monolayer and for the thickness determination of 2D ZrNCl. The back gate field-effect transistor based on few-layer ZrNCl shows a high on/off ratio of 10 8 . These results suggest the potential of 2D β-ZrNCl for electronic applications.
研究领域:
材料科学
·
电子工程
✓ 已验证
DOI
PubMed
高影响因子
Green Synthesis and Catalysis
·
2022
·
IF 0
Mariam Iqbal,Yuefeng Deng,Qiaoyue Chen,Chengli Yang,Yihui Zhu,Ziqian Chen,Jianjun Wang,Kaishun Hu,Guanya He,Dali Li
Nanotechnology has become the most promising domain to boost the efficiency of enzymes. Enzymes are vital as a green catalyst in many industries, food, pharmaceutical and biomedical, etc. The immobilization process of the enzyme increases its catalytic properties. In this research, a novel method is presented to describe the effect of nano-calcium carbonate on the characteristics of immobilized β -glucosidase, which was extracted from the Agrocybe aegirit . The nano-CaCO 3 was produced using the eco-friendly natural deep eutectic solvent. The pure nano -CaCO 3 was observed as vaterite, with a size of about 300 nm. The nano-calcium carbonate was coated by a natural polymer sodium alginate compound and then adsorbed chitosan. Further, this obtained composite is cross-linked by the bioactive genipin to immobilize the β -glucosidase. The enzyme/protein loading ratio to the supports was 1:4, respectively. The recovery efficiency of immobilized β -glucosidase was 89.3%, and immobilization yield was 96.452%. Chitosan-coated nano-CaCO 3 was used as a carrier for immobilization of β -glucosidase to improve its stability and reusability. In addition to stability and reusability, pH tolerance, temperature tolerance, and enzyme kinetics are the significant parameters that illustrate the proficiency of an immobilized enzyme. The measured optimal enzymatic reaction conditions for the immobilized β -glucosidase were 50 °C and pH 6. Furthermore, it has shown noticeable improvements in thermo-stability and pH tolerance. Temperature tolerance was observed 50% to the initial activity of the immobilized enzyme even after the 3 h of incubation at 50 °C, while pH tolerance was noticed more than 50% and 40% at pH 7 and 8, respectively. The K m and V max values of free and immobilized β -glucosidase to 4-nitrophenyl β -D-glucopyranoside were 1.549 μmol/L/min, 0.346 mmol/L and 0.532 μmol/L/min, 0.080 mmol/L, respectively. The immobilized β -glucosidase retains its storability 80% even after 30 days of storage at 4 °C and maintains 93.1% of its residual activity by reusing up to 10 cycles.
研究领域:
生物技术
·
酶工程
·
材料科学
✓ 已验证
DOI
危险品化学品经营许可证（带存储）