BIOELECTROCHEMISTRY
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2023
·
IF 5
Jianhua Yan,Kaidi Wang,Hongjie Liu,Liwei Wang,Yixiang Li,Guoqing Zhang,Li Deng
MiRNA-155 is a typical biomarker for breast cancer. Since its low concentration in the physiological environment and the limitations of conventional miRNA detection methods like Northern imprinting and RT-qPCR, convenient, real-time, and rapid detection methods are urgently needed. In this work, an electrochemical biosensor was constructed based on the flower-like MoSe 2 @1T-MoS 2 heterojunction electrode material and specific RNA recognition probes, which can realize the rapid determination of miRNA-155 content with a wide detection range from 1 fM to 1 nM and a limit of detection (LOD) as low as 0.34 fM. Furthermore, the contents of miRNA-155 in blood samples of tumor-bearing mice and normal mice were measured as 724.93 pM and 21.42 pM, respectively by this biosensor, demonstrating its strong identification ability and miRNA-155 can be regarded as an ideal diagnostic marker. On this basis, a portable sensor platform was designed for on-site detection simulation and showed good recovery efficiency from 95.80% to 98.69%. Meanwhile, compared with the standard detection method RT-qPCR, the accuracy and reliability of the biosensor were verified, indicating that the biosensor has the potential to provide point-of-care testing (POCT) for the early diagnosis of breast cancer.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2022
·
IF 6.911
Mengyang Li,Baoshan He,Haoyang Yan,Lingling Xie,Xiaoyu Cao,Huali Jin,Min Wei,Wenjie Ren,Zhiguang Suo,Yiwei Xu
A novel ultrasensitive electrochemical aptasensor was proposed for quantitative detection of Cd 2+ . To this end, flower-like polyethyleneimine-functionalized molybdenum disulfide-supported gold nanoparticles (PEI-MoS 2 [email protected] NPs) were used as substrates for the modification of bare gold electrodes (AuE). PEI-MoS 2 [email protected] NPs not only possessed excellent biocompatibility and large specific surface area to enhance the cDNA loading capacity, but also possessed good conductivity to accelerate the electron transfer rate. Furthermore, the preparation of dendritic platinum-palladium nanoparticles (PtPd NPs) can effectively load Cd 2+ -aptamer. Thionine and aptamers were loaded onto PtPd NPs to construct Thi-PtPd NPs-aptamer signal probes. The signal probes were captured by the cDNA immobilized on the electrode via base-pairing rule, and the signal of Thi was detected by differential pulse voltammetry (DPV). In the presence of Cd 2+ , aptamer-cDNA unwinded, and the combination of aptamer and Cd 2+ caused the signal probes to fall off the electrode and the electrical signal decreases. Under optimal conditions, the proposed aptasensor exhibited a linear relationship between the logarithm of Cd 2+ concentration and the current response over a wide range of 1 × 10 −3 nM to 1 × 10 2 nM, with a detection limit of 2.34 × 10 −4 nM. At the same time, the aptasensor was used to detect Cd 2+ in tap water with satisfactory results. In addition, it has good reproducibility, selectivity and stability, and has broad application prospects in heavy metal analysis.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Hu Zhou,Shuai Wang,Jinyue Jiang,Li Shao,Dan Li,Jiren Yuan,Feigao Xu
Magnetic Fe 3 S 4 /MoS 2 composites with a visible light response were prepared, and their degradation activity was tested using tetracycline hydrochloride (TCH) as a simulated pollutant. The mass ratios of Fe 3 S 4 and MoS 2 , pH change, temperature, H 2 O 2 concentration, and catalyst addition were investigated to determine the mechanism of TCH degradation. The results show that the removal rate of TCH by the Fe 3 S 4 /MoS 2 composites is much higher than that of the pure Fe 3 S 4 or MoS 2 under pH values ranging from 1.2 to 13.2. The removal rate of TCH by Fe 3 S 4 /MoS 2 was 376.37 and 5.45 times higher than that of pure Fe 3 S 4 and MoS 2 when the mass ratio of Fe 3 S 4 and MoS 2 was 1:1 at pH 7.2. The main free radicals and metal leaching changes are analyzed. The removal mechanism of TCH was proposed by the free radical scavenger test and the metal leaching test. The mechanism proposed in this paper shows that the high catalytic activity of Fe 3 S 4 /MoS 2 composite is due to the acidic microenvironment near the surface of the composite, which reduces the production of ferric hydroxide sludge.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Lijun Zhang,Zhiliang Jin,Noritatsu Tsubaki
As a crucial part of artificial photosynthesis, the design of the catalyst is important essential. Among them, the interface engineering between semiconductors and the construction of surface-active sites play a vital role in generating and transporting light-excited electrons, which can ultimately accelerate water decomposition. Therefore, the MoS 2 @MoO 3 step (S)-scheme heterojunction photocatalyst was prepared by in-situ partial sulfidation. The excellent interface engineering of MoS 2 @MoO 3 nanomaterials achieves a high surface reaction rate. The in-situ vulcanization strategy gradually corrodes from the outside to the inside. The introduction of sulfur atoms can replace oxygen atoms to build a sulfur-rich surface and generate molybdenum sulfide. The amount of thioacetamide is adjusted to control vulcanization and optimizing the experimental conditions, the best hydrogen production rate is 12416.8 µmol h −1 g −1 . An in-situ irradiation XPS experiments and DFT calculations provide a deeper understanding of the S-scheme electron transport mechanism in MoS 2 @MoO 3 . MoS 2 @MoO 3 interface interaction has penetrating electron channels and a strong interface interaction force, which effectively promotes the charge transfer between interfaces. This gradual surface vulcanization strategy provides new ideas for introducing synergistic surface-active sites and optimizing interface engineering photocatalyst projects.
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NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 27
·12670-12677
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IF 3.3
Weiwen Cao,Xuanyu Yang,Weiji Dai,Bing Wu,Yudong Zhang,Cuijiao Zhao,Yanwei Sui,Saifang Huang
Efficient and robust electrocatalysts towards the oxygen evolution reaction (OER) are highly desirable in electrochemical systems for applications including water splitting and metal-air batteries. Herein, we report the preparation of an amorphous FeCoNiMnCr high-entropy alloy (HEA) on the surface of flower-like 2H-MoS2 (FeCoNiMnCr@MoS2) as a highly efficient electrocatalyst for the OER. The flower-like 2H-MoS2 is prepared on the flexible conductive carbon cloth (MoS2-CC) via a hydrothermal method, and subsequently the amorphous FeCoNiMnCr HEA is loaded on the surface of 2H-MoS2via an electrodeposition method to form FeCoNiMnCr@MoS2-CC electrocatalysts. Owing to the unique microstructure of 2H-MoS2 and abundant active sites of FeCoNiMnCr HEA, the FeCoNiMnCr@MoS2-CC electrocatalysts exhibit significantly improved OER electrocatalytic performances with a low overpotential of 210 mV at a current density of 10 mA cm−2 and a small Tafel slope of 40.3 mV dec−1 in 1.0 M KOH solution. Moreover, it shows excellent stability for OER electrocatalysis with the potential barely increased for at least 50 h. This work sheds light on the development of highly efficient OER electrocatalysts based on HEAs.
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CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Yuxuan He,Jin Qian,Peifang Wang,Jie Wu,Bianhe Lu,Sijing Tang,Pan Gao
The nanocomposite of MoS 2 embedded manganese ferrite doped perovskite (SrCoO 3 /MnFe 2 O 4 /MoS 2 , abbreviated as SMM) was successfully synthesized for peroxymonosulfate (PMS) activation under visible-light. It was optimized that the SMM-3 (mass ratio of MoS 2 modified nanocomposite was 0.3) exhibited excellent catalytic performance to activate PMS for levofloxacin (LVF) degradation, with the degradation efficiency of 95.1% in 20 min. Besides, SMM-3 was able to efficiently degrade LVF under real water matrix. The quenching experiments and electron paramagnetic resonance (EPR) analysis revealed that SO 4 •- and HO • played a dominant role in reaction. Due to the photocatalytic property of nanocomposites, the visible light could excite electrons to react with oxygen and form O 2 •- , which further reacted with HO • to produce 1 O 2 . In the reaction process, the rapid redox cycle of metal ions (including Co, Mn, Fe and Mo) boosted the activation of PMS and promoted the degradation of LVF in a short time. The Density functional theory (DFT) calculation and LC-MS/MS further revealed that oxidation of piperazine ring, decarboxylation and defluorination processes were the main LVF degradation pathways. Finally, the toxicity analysis based on Toxicity Estimation Software Tool (T.E.S.T) verified the ecological risks of transformation residues.
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Journal of Water Process Engineering
·
2023
·
IF 7
Chumin Yan,Xiaoli Dong,Yu Wang,Nan Zheng,Hongchao Ma,Xiufang Zhang
Inorganic semiconductors prepared from MOFs as sacrificial precursors are promising photocatalytic materials. In this work, the direct Z -scheme MoS 2 /NH 2 -MIL-68(In)-derived In 2 S 3 (MoS 2 /In 2 S 3 ) heterojunction composites have been synthesized by sulfidation treatment of MoS 2 /NH 2 -MIL-68(In) (MoS 2 /NM68) composites. Morphological and crystal structural results confirmed that MoS 2 was uniformly dispersed in In 2 S 3 . According to the reduction for Cr(VI) experimental results, the photocatalytic performance of MoS 2 /In 2 S 3 heterojunction composite under visible light irradiation is significantly better than that of pristine MoS 2 and In 2 S 3 , respectively. In addition, the photocatalytic activities of the MoS 2 /In 2 S 3 (II) at different pH and high concentrations of Cr(VI) were also investigated. This paper presents a novel approach to the construction of heterojunction photocatalytic materials using MOFs as sacrificial precursors.
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2021
·
IF 6.291
Wenyan Shi,Yuting Chu,Mingzhu Xia,Fengyun Wang,Chenlu Fu
MoS 2 /montmorillonite (MoS 2 /Mt) composite was successfully synthesized through a simple hydrothermal method, and its adsorption performance for two emerging contaminants-atenolol (ATE) and acebutolol (ACE) was researched. The batch experiments revealed that the adsorption process can be described by the Pseudo-second order model and Langmuir model, and the adsorption capacity of MoS 2 /Mt, MoS 2 and Mt for ATE were 132.08 mg/g, 60.68 mg/g and 74.23 mg/g, for ACE were 113.82 mg/g, 33.01 mg/g and 36.05 mg/g, respectively. Besides, Fourier-transform infrared spectroscopy (FTIR), BET specific surface area measurement and X-ray photoelectron spectroscopy (XPS) were also employed to analyze the adsorption mechanism. Moreover, quantitative molecular surface analysis and weak intermolecular interaction analysis with independent gradient model were combined to probe the microscopic interaction between the adsorbent and adsorbate. The results indicated the interactions included hydrogen bonding and vdW interaction. Mt and MoS 2 interacted more strongly with ATE than ACE, which revealed the reason MoS 2 /Mt, Mt and MoS 2 possessed higher adsorption capacity for ATE.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Lian Ma,Jiao Zhu,Chao Wu,Duo Li,Xuehui Tang,Yue Zhang,Changhua An
Well-dispersed Prussian blue (PB) and Au nanoparticles (Au NPs) loaded three dimensional MoS 2 nanoflowers (PB-Au@MoS 2 NFs) was synthesized by a simple and economical method. The structure, morphology and composition of the hybrid were characterized by XRD, SEM and EDS. Similar to the reported literature, MoS 2 nanoflowers showed peroxidase-like activity in catalyzing the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB). This peroxidase-mimicking activity could be enhanced with the introduction of PB and Au NPs. Herein, PB-Au@MoS 2 NFs could be used to establish a new platform for the determination of H 2 O 2 and glucose by the chromogenic reaction. Wide linear ranges with 0–15 μM and 0–120 μM for H 2 O 2 and glucose detection were finally obtained. The detection limits were as low as 0.25 μM and 3 μM (with signal to noise ratio of 3), respectively. The established platform was also used successfully for the determination of glucose in human serum and fruit juice samples with excellent sensitivity and stability.
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Journal of the Taiwan Institute of Chemical Engineers
·
2020
·
IF 4.794
Xinlin Liu,Lingyan Xu,Guosheng Zhou,Qian Liu,Minshan Song,Song Han,Sivakumar Esakkimuthu,Jessica Vinh,Bahram Barati,Ziyang Lu
In this work, BiVO 4 /MoS 2 (BM) heterojunction was prepared by combining ultrasonic agitation exfoliation and in-situ growth method. Since flower-like MoS 2 comprised a larger contact area with pollutants, by decorating dewdrops-shaped BiVO 4 on the flower-like MoS 2 , h + on BiVO 4 can be transferred to MoS 2 . Therefore, h + with strong oxidizing ability enriched on MoS 2 can effectively attack the pollutants and substantially improve the photocatalytic activity of the as-prepared heterojunction. The degradation rate of tetracycline with BiVO 4 /MoS 2 heterojunction (68.83 % in 120 min) was 5.64 and 4.23 times that with pure MoS 2 (12.19 %) and pure BiVO 4 (16.26 %), respectively. This work provided a new idea for the construction of highly active MoS 2 -based heterojunctions.
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ChemElectroChem
·
2020
·Vol. 7
·期 15
·3260-3268
·
IF 4.154
Moujie Huang,Huanhui Chen,Jiao He,Junning Chen,Lingna Sun,Yongliang Li,Xiangzhong Ren,Libo Deng
Graphical Basic instinct : Catalysts comprising MoS 2 incorporated into 3D hierarchically N,S co-doped carbon composites (MoS 2 @NSC) are prepared by using functional fluidic acrylonitrile telomer as a carbon source and doping agent, and SiO 2 as a hard template. The optimal catalyst exhibits effective oxygen reduction reaction catalytic activity with the initial potential of 0.93 V and half-potential of 0.82 V in basic electrolyte with a four-electron reduction process and a superior durability and methanol tolerance. Catalysts comprising MoS 2 incorporated into 3D hierarchically N,S co-doped carbon composites (MoS 2 @NSC) were prepared through a facile and scalable method by using the functional fluidic acrylonitrile telomer as a carbon source and doping agent, and SiO 2 as a hard template. The optimal catalyst, MoS 2 @NSC-2, showed effective oxygen reduction reaction (ORR) catalytic activity with the initial potential of 0.93 V and half-potential of 0.82 V in basic electrolyte. In addition, MoS 2 @NSC-2 favored a four-electron reduction process and demonstrated a superior durability and methanol tolerance, which could be ascribed to its unique porous structure that can effectively facilitate the transfer of electrolyte and O 2 molecules. The Mo−N x species are formed due to the doping of N atoms into the crystal lattice of MoS 2 , which can further enhance the ORR catalytic activity. Our work affords a forward-looking strategy for designing efficient and low-cost ORR catalysts on a large scale.
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ACS Sensors
·
2021
·
IF 7.711
Zongbao Sun,Yunlong Gao,Zeng Niu,Haodong Pan,Xuechao Xu,Wen Zhang,Xiaobo Zou
Paper-based fluorescence devices, with smartphone aids, bring considerable operation convenience for tetracycline (TC) sensing. Nevertheless, they must meet the challenge in real determination against complicated backgrounds. Considering that, we present a programmable-printing paper-based device and then apply it to TC determination for various natural samples. MoS2 NPs and Gmp/Eu-Cit are synthetized as composite probes. A static quenching process is found with MoS2 NP fluorescence at 430 nm, while significant magnification of Gmp/Eu-Cit emission is obtained at 617 nm, establishing a valuable ratiometric indicator. Remarkably, two-stage programmable printing maximizes the proposed sensing capability. A transitive device, containing a gradually changing amount of a certain probe, is prepared to sense TC. With a homemade smartphone application and 3D-printed measurement chamber, the corresponding signals are examined to explore optimal setups. These setups are automatically processed to prepare the final-version device, not requiring manual operations. Benefitting from this interesting feature, the proposed device gains many rewards in performances. It effectively senses TC in a wide range from 12.7 nM to 80 μM and simultaneously provides naked eye-legible signals and smartphone-based readouts with confident selectivity and stability. This device is consequently applied for various samples of soil, river water, milk, and serum and meets well with HPLC–MS and recovery tests.
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