JOURNAL OF NANOBIOTECHNOLOGY
·
2024
·Vol. 22
·期 1
·1-21
·
IF 10.6
Xu Wenhao,Ye Shiqi,Liu Wangrui,Guo Huaqi,Zhang Linhui,Wei Shiyin,Anwaier Aihetaimujiang,Chang Kun,Malafaia Guilherme,Zhang Hailiang,Ye Dingwei,Wei Gang
In recent years, the environmental health issue of microplastics has aroused an increasingly significant concern. Some studies suggested that exposure to polystyrene microplastics (PS-MPs) may lead to renal inflammation and oxidative stress in animals. However, little is known about the essential effects of PS-MPs with high-fat diet (HFD) on renal development and microenvironment. In this study, we provided the single-cell transcriptomic landscape of the kidney microenvironment induced by PS-MPs and HFD in mouse models by unbiased single-cell RNA sequencing (scRNA-seq). The kidney injury cell atlases in mice were evaluated after continued PS-MPs exposure, or HFD treated for 35 days. Results showed that PS-MPs plus HFD treatment aggravated the kidney injury and profibrotic microenvironment, reshaping mouse kidney cellular components. First, we found that PS-MPs plus HFD treatment acted on extracellular matrix organization of renal epithelial cells, specifically the proximal and distal convoluted tubule cells, to inhibit renal development and induce ROS-driven carcinogenesis. Second, PS-MPs plus HFD treatment induced activated PI3K-Akt, MAPK, and IL-17 signaling pathways in endothelial cells. Besides, PS-MPs plus HFD treatment markedly increased the proportions of CD8 + effector T cells and proliferating T cells. Notably, mononuclear phagocytes exhibited substantial remodeling and enriched in oxidative phosphorylation and chemical carcinogenesis pathways after PS-MPs plus HFD treatment, typified by alterations tissue-resident M2-like PF4 + macrophages. Multispectral immunofluorescence and immunohistochemistry identified PF4 + macrophages in clear cell renal cell carcinoma (ccRCC) and adjacent normal tissues, indicating that activate PF4 + macrophages might regulate the profibrotic and pro-tumorigenic microenvironment after renal injury. In conclusion, this study first systematically revealed molecular variation of renal cells and immune cells in mice kidney microenvironment induced by PS-MPs and HFD with the scRNA-seq approach, which provided a molecular basis for decoding the effects of PS-MPs on genitourinary injury and understanding their potential profibrotic and carcinogenesis in mammals. Graphical Abstract
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PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2023
·Vol. 34
·期 31
·1-12
·
IF 2.8
Ma Juncheng,Xiong Zhe,Xiong Ying,Zhang Xing,Tang Bin
The purpose of this study was to synthesize a low-firing ceramic, namely Li 2 O–B 2 O 3 –SiO 2 (LBS) glass-doped 0.35Na 0.5 Nd 0.5 TiO 3 –0.65Li 0.5 Nd 0.5 TiO 3 (NLNT), with desired properties including a high dielectric constant ( ɛ r ), high quality factor ( Q × f ), and near-zero temperature coefficient of resonant frequency ( τ f ). The NLNT ceramic was synthesized using the solid-state reaction method, and XRD analysis confirmed the presence of a single perovskite phase in all NLNT + x wt% LBS ( x = 0, 2, 3, 4, 5) ceramic samples. The LBS glass demonstrated excellent wetting behavior on the NLNT ceramic, ensuring effective densification at low sintering temperatures. The grain size, bulk density, densification temperature, and microwave dielectric properties were influenced by the doping level of LBS glass. Ultimately, NLNT + 4 wt% LBS glass sample, sintered at 950 °C, exhibited favorable microwave dielectric properties: ɛ r = 110.9, Q × f = 2,065 GHz, and τ f = + 4.6 ppm/°C.
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高影响因子
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING
·
2015
·Vol. 20
·期 5
·901-907
·
IF 1.113
Yang Jianbing,Ni Kefeng,Wei Dongzhi,Ren Yuhong
Ni 2+ -functionalized Fe 3 O 4 @polydopamine magnetic nanoparticles (Ni 2+ -PD-MNPs) were designed and synthesized by in situ coating of magnetic nanoparticles with polydopamine, followed by conjugation of Ni 2+ to the polydopamine film. The Ni 2+ -PD-MNPs were used to purify His-tagged red fluorescent protein (His-RFP) via affinity interaction between Ni 2+ and the His-tag. The results showed that the Ni 2+ -PD-MNPs had extraordinary selectivity for His-RFP purification. In addition, a Histagged transaminase (ω-transaminase BJ110) was selectively immobilized onto the Ni 2+ -PD-MNPs without purification, and the immobilized enzyme showed improved specific activity, as well as enhanced stability and reusability.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2019
·Vol. 54
·期 16
·11024-11036
·
IF 3.442
Yang Lu,Wang Yanhua,Liu Aihua,Zhang Yang
A novel biomass carbon doped with dual-metal oxide mischcrystal (cobalt oxide and molybdenum oxide) was synthesized by using Enteromorpha (EP) of marine algae as carbon source. Multi-wrinkles biomass carbon (MWBC) with magnetic properties was obtained and formed highly dispersed CoO x /MoO y nanoparticles onto the surface of MWBC in situ via a simple impregnation and direct carbonization at 700 °C. The framework of CoO x /MoO y @MWBC was characterized by scanning electron microscopy, transmission electron microscope, X-ray diffraction and X-ray photoelectron spectroscopy. The as-prepared CoO x /MoO y @MWBC was applied as efficient adsorbents for selective removal methyl blue (MB) at pH 10 from water medium. For comparison, single metal-derived porous carbon, i.e., CoO x @MWBC and MoO y @MWBC, was also synthesized, characterized and tested for MB adsorption. The results exhibited that CoO x /MoO y @MWBC has the highest MB adsorption capacity (1587.3 mg g −1 ) and excellent selectivity. In addition, it could be easily separated from water by an external magnetic field without any organic reagent added. Adsorption equilibrium data were described by Langmuir and Freundlich isotherms, and kinetic data were described by pseudo-first-order, pseudo-second-order and intraparticle diffusion model. Moreover, CoO x /MoO y @MWBC also owned outstanding stability and renewability, which can be regenerated by an easy-going method of ethanol washing and reused at least 10 times without a significant loss in removal percentage.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2020
·Vol. 31
·期 21
·19381-19387
·
IF 2.22
Qing Zhenjun,Cheng Jiawen,Li Haiyan,Xue Yan
The Ba 1+ x Cu 2 V 2 O 8 ( x = 0.15, 0.25, 0.35) ceramics were synthesized using the conventional solid-state reaction sintering method. The effects of the non-stoichiometry on the crystalline phases, densification sintering, microtopography, and microwave dielectric properties of the Ba 1+ x Cu 2 V 2 O 8 ( x = 0.15, 0.25, 0.35) ceramics were studied. In the sample ( x = 1) prepared according to the stoichiometry, only the single crystalline phase of BaCu 2 V 2 O 8 existed. The excess of Ba 2+ ions directly led to the precipitation of a new Ba 2 V 2 O 7 phase. The detection of element composition using EDS also confirmed the results of the phase composition. The SEM results indicated that the microstructure of the ceramics became loose with the increase of Ba 2+ ion content. The theoretical microwave dielectric properties were calculated according to the general formula of compounds. The results of the calculation showed that the precipitation of the Ba 2 V 2 O 7 phase was the main factor affecting the microwave dielectric properties of the ceramics. The measured results of microwave dielectric properties were consistent with the calculated results. The microwave dielectric properties of the Ba 1.35 Cu 2 V 2 O 8 sample calcined at 725 °C for 6 h were shown as follow: ε r = 12.25, Q f = 46,320 GHz, τ f = − 35.3 ppm/°C.
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高影响因子
Scientific Reports
·
2020
·Vol. 10
·期 1
·1-9
·
IF 3.998
Nie Wenjie,Li Yani,Chen Leyuan,Zhao Zhicheng,Zuo Xin,Wang Dongdong,Zhao Lei,Feng Xinyue
Carbon nanotubes could accumulate in organism and have a negative impact on the structure and function of the ecosystem when they were discharged into environment. Furthermore, it will affect the migration and fate of pollutants in the water body. The study is mainly to explore the adsorption behavior and mechanism of beta-blocker on multi-walled carbon nanotubes (MWCNTs). Propranolol (PRO) was selected as the representative of beta-blocker. The effects of different environmental factors such as pH, ionic strength and humic acid (HA) on the adsorption process were investigated. The adsorption results were characterized by Zeta potential. At the same time, the effects of different types of drugs on the adsorption process were explored and the possible adsorption mechanisms were analyzed. The experimental results showed that the adsorption behavior was significantly different under different pH conditions. π-π EDA interaction, hydrophobic interaction and hydrogen bonding were speculated to be the main adsorption mechanisms for PRO adsorption on MWCNTs.
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PubMed
高影响因子
CHROMATOGRAPHIA
·
2018
·Vol. 81
·期 9
·1317-1323
·
IF 1.401
Zhang Chaozheng,Tang Ping,Xu Huijing,Weng Yanru,Tang Qiaoqiao,Zhao Hua
The level of short-chain fatty acids (SCFAs) is related to health benefits. In this study, a static headspace (HS) gas chromatography method was developed and validated for analyzing SCFAs in fecal samples. SCFAs were injected onto a column through an HS injector through an HS procedure and salting-out technology. The limits of detection and quantification (LOQ) of this method are 0.02–0.08 µg L − 1 (0.4–1.6 µg g − 1 sample) and 0.005–0.020 µg L − 1 (0.1–0.4 µg g − 1 sample), respectively. The calibration curves show good linearity over the range (LOQ–200 µg L − 1 or LOQ–4000 µg g − 1 sample) of these compounds, and the correlation coefficient is > 0.99. The recovery of the method is between 80 and 105%, and matrix effects were not observed. The proposed method was successfully applied to analyze SCFAs in fecal samples from rats. Graphical Abstract
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2017
·Vol. 24
·期 5
·1-9
·
IF 1.615
Xue Sheng,Yang Haicun,Ma Wenzhong,Gong Fanghong,Tao Guoliang,Liu Chunlin,Pan Ji
Poly(methyl methacrylate) brushes grafted from attapulgite nanoparticles (ATP@PMMA) were prepared by R-Supported reversible addition-fragmentation chain transfer polymerization (RAFT). ATP was firstly activated, and allowed to react with γ-aminopropyltriethoxysilane (APTES), 4,4′-azobis(4-cyanovaleric acid) (ACVA) and bis(thiobenzoyl) disulfide stepwise to afford 4-cyanopentanoic acid dithiobenzoate functionalized ATP (ATP-CPADB). Then, RAFT polymerizations of MMA mediated by the different systems were conducted and compared systemically. The grafting process was verified by FTIR, XRD, XPS, TGA and TEM data. Kinetic behavior indicated that the anchored CPADB is more effective before diffusing into the bulk phase. The grafting ratio ( G
r ), while M
n of grafted and free polymer increased linearly with increasing monomer conversion in presence of free CPADB, giving the hybrid particles with more homogeneous distribution of grafted polymer layer.
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高影响因子
Journal of Advanced Ceramics
·
2022
·Vol. 11
·期 10
·1654-1670
·
IF 11.534
Wu Jinyu,Ma Xiaohui,Hu Xiaoxia,Yan Liwen,Hou Feng,Liu Jiachen,Guo Anran
As a type of titanate, the pseudobrookite (MTi 2 O 5 /M 2 TiO 5 ) exhibits a low thermal expansion coefficient and thermal conductivity, as well as excellent dielectric and solar spectrum absorption properties. However, the pseudobrookite is unstable and prone to decomposing below 1200 °C, which limits the practical application of the pseudobrookite. In this paper, the high-entropy pseudobrookite ceramic is synthesized for the first time. The pure high-entropy (Mg,Co,Ni,Zn)Ti 2 O 5 with the pseudobrookite structure and the biphasic high-entropy ceramic composed of the high-entropy pseudobrookite (Cr,Mn,Fe,Al,Ga) 2 TiO 5 and the high-entropy spinel (Cr,Mn,Fe,Al,Ga,Ti) 3 O 4 are successfully prepared by the in-situ solid-phase reaction method. The comparison between the theoretical crystal structure of the pseudobrookite and the aberration-corrected scanning transmission electron microscopy (AC-STEM) images of high-entropy (Mg,Co,Ni,Zn)Ti 2 O 5 shows that the metal ions (M and Ti ions) are disorderly distributed at the A site and the B site in high-entropy (Mg,Co,Ni,Zn)Ti 2 O 5 , leading to an unprecedentedly high configurational entropy of high-entropy (Mg,Co,Ni,Zn)Ti 2 O 5 . The bulk high-entropy (Mg,Co,Ni,Zn)Ti 2 O 5 ceramics exhibit a low thermal expansion coefficient of 6.35×10 −6 K −1 in the temperature range of 25–1400 °C and thermal conductivity of 1.840 W·m −1 ·K −1 at room temperature, as well as the excellent thermal stability at 200, 600, and 1400 °C. Owing to these outstanding properties, high-entropy (Mg,Co,Ni,Zn)Ti 2 O 5 is expected to be the promising candidate for high-temperature thermal insulation. This work has further extended the family of different crystal structures of high-entropy ceramics reported to date.
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高影响因子
FIBERS AND POLYMERS
·
2016
·Vol. 17
·期 2
·194-198
·
IF 1.022
Xing Guiying
Aminated polyacrylonitrile (PAN-NH) nanofiber mats prepared by electrospinning and then aminated by multiamines with different chemical structures have been used for the immobilization of palladium. The PAN-NH fiber morphologies were characterized by scanning electron microscopy (SEM) and the dispersion of palladium particles on the PAN-NH fiber were examined by transmission electron microscopy (TEM). The catalytic activity and recyclability of the prepared heterogeneous palladium catalysts have been evaluated by the Heck reaction of iodobenzene with n -butyl acrylate. It was found that the catalytic activities of PAN-NH-Pd catalysts could be correlated with the chelating energies of the PAN-NH fiber mats with Pd active species.
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高影响因子
Biomass Conversion and Biorefinery
·
2022
·
IF 4.05
Li Keying,Zhu Hengji,Zhao Yu,Yan Jingwei,Zhang Jiajian,Lin Xiuhua,Fan Liwei,Lu Zexiang
The solvent has an important impact on liquefaction conversion from biomass to efficiently obtain fuels and chemicals. In this paper, the catalytic liquefaction of woody biomass was studied using fir sawdust as raw material and concentrated sulfuric acid as catalyst in GVL/1-octanol mixed solvent with mechanical stirring and oil bath heating. The influence of GVL on liquefaction yield was discussed, and the liquefaction productions were characterized by some analysis methods to analyze the liquefaction mechanism. The results show that adding GVL benefits to improving liquefaction yield and generating high value-added monophenol because of the enhancement of the surface wettability of biomass and the inhibition of polymerization of mononuclear aromatics with other degradation products. The maximum liquefaction yield of 76.07% was obtained under the suitable conditions of fir sawdust 10 g, temperature 150 ℃, reaction time 60 min, mass ratio of sawdust/solvent 1:6, catalyst concentration 0.6 mol·L −1 , and mass ratio of GVL/1-octanol 4:6. The mechanism study reveals that aromatics originated by lignin degradation as well as small molecule ketones from cellulose and hemicellulose degradation. GVL/1-octanol as an eco-friendly solvent system exhibits a promising prospect of application in woody biomass conversion. Graphical abstract
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2018
·Vol. 30
·期 1
·212-220
·
IF 2.324
Hu Zhen,Zhao Li,Guo Haiyong,Wang Shimin,Li Wenlu,Yang Xiaojie,Dong Binghai,Wan Li
A novel composite double-layer film was developed using TiO 2 /La(OH) 3 :Yb 3+ /Er 3+ nanoparticles (P25/UC) and porous-hollow TiO 2 microspheres (PHTS) for highly efficient dye-sensitized solar cells (DSSCs). P25/UC was used as the first layer and coated onto fluorine-doped tin oxide glass substrate to create a good contact and upconversion effect. The P25/UC layer can absorb and convert infrared light into visible red and green light, increasing light utilization. PHTS has a large size and a high specific surface area, was deposited onto the surface of the P25/UC film to improve the light scattering performance and dye adsorption of solar cells. The P25/UC composite double-layer film (P25/UC + PHTS) achieved the highest short-circuit current density of 20.33 mA/cm 2 and photoelectron conversion efficiency of 8.89% due to the synergistic effect of the upconversion layers and light-scattering layers, which increased by 51.26% and 38.04% compared with that of the pure P25 film photoelectrode.
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高影响因子
危险品化学品经营许可证（带存储）