TALANTA
·
2024
·
IF 5.6
Yu Tao,Haixia Wang,Enguo Ju,Yeh-Hsing Lao,Yu Zhang,Mingqiang Li
Diseases caused by viruses, such as monkeypox virus (MPXV) and human papillomavirus (HPV), pose serious threats to human health and safety. Although numerous strategies have been constructed for detecting MPXV and HPV DNA, most methods require either laborious procedures or complicated instruments involving skilled professionals. In this research, a CRISPR-Cas12a-mediated colorimetric detection platform for MPXV and HPV sensing was constructed for the first time by applying probe DNA to reprogram the catalytic properties of molybdenum disulfide quantum dots (MoS 2 QDs). In the presence of MPXV or HPV targets, the CRISPR-Cas12a trans -cleavage activity is effectively motivated to decompose the probe DNA, leading to the suppression of enzymatic activity DNA enhancer adsorbed on MoS 2 QDs, resulting in greatly decreased catalytic behaviors. The MoS 2 QDs-DNA nanohybrids displayed prominent specificity and sensitivity, with detection limits at subpicomolar levels, as well as excellent stability and accuracy for determining MPXV and HPV DNA in human sera biosamples. Furthermore, the proposed colorimetric biosensing approach can be ensembled with a smartphone platform, allowing visible analysis of DNA targets. Taken together, this colorimetric strategy offers a novel diagnosis method for MPXV and HPV DNA detection, particularly favorable for highly endemic developing countries with restricted medical and instrumental support.
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DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Li Wang,Meng Zhang,Yufei Shu,Qi Han,Li Long,Beizhao Chen,Mengxia Wang,Li Li,Siyu Cao,Zhe Yang,Bei Liu,Zhongying Wang,Chuyang Y. Tang
Thin film nanocomposite (TFNi) membranes interlayered with 2D nanomaterials are promising for organic solvent nanofiltration (OSN) applications. However, swelling and drying problems can arise due to the instability of the 2D nanomaterial interlayer in different solvents and humidity conditions. To address this issue, covalently modified molybdenum disulfide (MoS 2 ) nanosheets (MoS 2 –COOH and MoS 2 –CONH 2 ) were used as interlayers in the fabrication of TFNi membranes. The covalent groups acted as spacers to stabilize the interlayer spacing of the MoS 2 interlayer and regulate its structural stability in diverse solvents and drying conditions. The TFNi membranes interlayered with MoS 2 –COOH and MoS 2 –CONH 2 nanosheets demonstrated excellent structural stability and maintained their high permeance even after exposure to various solvents and drying conditions. The TFNi-MoS 2 -CONH 2 membrane exhibited the highest permeance of 8.60 ± 0.23 L m −2 h −1 bar −1 for MeOH, with a high rejection of 87.1 ± 1.3 % for Evans Blue (EB). Furthermore, the TFNi membranes exhibited sustained separation performance throughout the 72 h test, demonstrating their structural stability. This study highlights the potential of TFNi membranes interlayered with covalently modified MoS 2 nanosheets for OSN applications, providing high permeance and structural stability in diverse solvents and drying conditions.
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高影响因子
Analytical Methods
·
2024
·Vol. 16
·期 24
·3867-3877
·
IF 2.7
Xin Yao,Liyu Yang,Siyi Yang,Jinhui Shen,Danqun Huo,Huanbao Fa,Changjun Hou,Mei Yang
A Ti3C2Tx/MoS2/MWCNT@rGONR nanocomposite was prepared for the first time for building a sensitive electrochemical aptasening platform to simultaneously detect kanamycin (Kana) and chloramphenicol (Cap). Owing to their accordion-like structure, rich surface groups, and high charge mobility, Ti3C2Tx/MoS2/MWCNT@rGONR composites provided a spacious covalent immobilization surface and a better electrochemical aptasensing platform. The aptamers of Kana and Cap used in sensors enhance the selectivity. Furthermore, TiP, an ion exchanger, was used for loading more different metal ions functioning as labels to form a sandwich-type sensor together with Ti3C2Tx/MoS2/MWCNT@rGONR, improving the electrochemical sensitivity and obtaining a highly distinguishable signal readout. Under the optimized conditions, the sensor has good detection limits of 0.135 nmol L−1 and 0.173 nmol L−1 for Kana and Cap, respectively, at the same linearity concentration of 0.5–2500 nmol L−1. Finally, it was successfully applied for detection in milk and fish meat, and the results were compared with the standard method HPLC, indicating its great potential for food safety monitoring.
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PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Yifeng Lan,Yingqi Ma,Yingwen Xu,Yuan Zhang,Rujia Deng,Lulu Liu,Boya Hou,Haiyan Cui,Keming Yun,Zhiwen Wei,Yanli Wei
Effective truncation and mutation can obtain highly active nucleic acid aptamers for the target, especially avoiding non-specific binding, uncertainty to the tertiary structure and low binding affinity of the lengthy aptamer. In this work, a new aptamer, T-AF28 (28 nt) with better affinity to AFB1 was obtained by truncating 22 bases and mutating 3 bases of the reported AFB1 aptamer (50 nt), and the thermodynamic information, structural changes and binding domains of aptamer T-AF28 in the presence of AFB1 or AFM1 were further investigated by isothermal titration calorimetry, circular dichroism, and molecular dynamics. On this basis, Using optimized aptamers as recognition elements, a novel label-free and enzyme-free fluorescent aptasensor for AFB1 and AFM1 was developed by synergistic amplification effect of hybridization chain reaction (HCR) coupled molybdenum disulfide nanosheets and copper nanoparticles in situ synthesized (CuNPs) on an extra-long double-stranded template generated by HCR as the fluorescent probe. Under the optimal experimental conditions, sensitive and selective fluorescent detection of AFB1 and AFM1 was achieved with wide linear detection ranges of 0.030 ng/mL-46.8 ng/mL and 0.030 ng/mL-32.8 ng/mL, respectively. And this aptasensor can be applied to accurate detection of AFB1 and AFM1 in grains, edible oil, tea, and milk with the recovery in the range of 85.20 %-117.0 %. This work not only provides a theoretical basis for the design of AFB1 and AFM1 aptasensors and expands the application of AFB1 aptasensors in the field of food safety, but also breaks a new path for the development of HCR-MoS 2 Ns CuNPs aptasensors.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2018
·
IF 11.698
Yunpeng Liu,Yuhang Li,Feng Peng,Yuan Lin,Siyuan Yang,Shengsen Zhang,Hongjuan Wang,Yonghai Cao,Hao Yu
Recently, MoS 2 as an efficient co-catalyst has attracted much attention for photocatalytic water splitting. MoS 2 has two polymorphs: semiconducting phase (2H) and metallic phase (1T). The 2H- and 1T- MoS 2 show different reaction mechanism in photocatalytic H 2 evolution. However, so far, very few experiments have clearly evidenced the electron transfer process between TiO 2 and mixed phase MoS 2 . This study for the first time has reported a simple hydrothermal synthesis method to prepare mixed phase few-layer MoS 2 nanosheets coated on TiO 2 nanorod arrays (MoS 2 @TiO 2 ) with a conductive fluorine-doped tin oxide (FTO) as a substrate. The structure of mixed phase MoS 2 was characterized carefully. The designed MoS 2 @TiO 2 exhibits two times higher activity than Pt@TiO 2 for photocatalytic H 2 evolution. The reliable conclusion that the photo-generated electrons from TiO 2 to MoS 2 nanosheets has clearly been evidenced by photoelectrochemical analyses and in-situ KPFM experiments, and the mixed phase MoS 2 here is a co-catalyst such like Pt rather than as a semiconductor. This study not only presents a series of solid experimental evidences to verify the electrons transfer process and photocatalytic mechanism, but also provides a new method in substituting MoS 2 for noble metal Pt as co-catalyst in high-efficiency photocatalytic water splitting into hydrogen.
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高影响因子
APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Renhui Zhang,Xue Yang,Jibin Pu,Zhongyi He,Liping Xiong
We first fabricate MoS 2 nano-ball in isopropanol using sonication-assisted method. We systematically probe the lubrication mechanism of MoS 2 nano-ball in isopropanol. Hydroxylated MoS 2 nano-ball could effectively reduce the contact area for GCr15 steel balls and possess superior load-capacity and make the tribosystem achieve ultra-low friction and wear under 98 or 196 N and 600 rpm. For comparison, the lubricity of tribosystem sliding in isopropanol is conducted. Interestingly, graphene layers are formed sliding under 196 N and 600 rpm, the graphene-based transfer film on GCr15 steel ball makes the lubrication condition fast transfer from mixed lubrication condition to full film lubrication condition, which results in high friction and wear. The formation mechanism of graphene is discussed and proposed in details.
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高影响因子
MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Shufang Ren,Runyan Feng,Shounian Cheng,Liqiu Huang,Qingtao Wang,Zhixiang Zheng
In this work, an ultrasensitive electrochemical sensor towards quantitative detection of acetaminophen (AP) based on hybrid of metallic 1 T and semiconductive 2H phase molybdenum disulfide (1 T/2H MoS 2 ) anchored on rGO sensing platform was constructed. The XRD, FESEM, FETEM and XPS analysis indicates that nanoflowers 1 T/2H MoS 2 with walnut-like fold structure were in-situ loaded onto the surface of rGO nanosheets by the hydrothermal approach. The formation of stabilized 1 T MoS 2 is associated with the influence of GO. The electrochemical tests of CV, EIS and DPV show that the hybrid composite MoS 2 /rGO remarkably promoted the detecting performance owing to the increased conductivity of 1 T MoS 2 that can facilitate charge transfer kinetics, the great active sites on both basal and edge of planes of 1 T/2H MoS 2 and the synergic effect of 1 T/2H MoS 2 and rGO. After the test condition optimization, MoS 2 /rGO/GCE sensor has great electrocatalytic activity towards AP with wide linear range of 0.005–300 μM and low limit of detection of 1.7 nM (S/N = 3). Furthermore, the sensor shows excellent stability, repeatability, reproducibility and anti-interference performance. All results proved that the GO-assisted hydrothermal prepared hybrid 1 T/2H MoS 2 /rGO is promising material for electrochemical analysis.
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DOI
高影响因子
Journal of Materials Chemistry C
·
2025
·Vol. 13
·期 8
·4145-4152
·
IF 5.1
Qingwei Zhou,Hansheng Li,Fan Wu,Dan Chen,Fang Luo,Chucai Guo,Zhihong Zhu
Controlling the interface energy level and simultaneously passivating the surface defects of perovskite films are crucial for improving the efficiency and stability of perovskite solar cells (PSCs). In this study, two-dimensional MXene nanoflakes grafted with MoS2 quantum dots (QD) are utilized as multifunctional interlayers at the interface of perovskite/carbon in all-inorganic CsPbBr3 PSCs, aiming to enhance their performance and stability. MoS2 QDs are grafted onto the surface of MXene to use the unsaturated S atoms at the edge of MoS2 to passivate the under-coordinated Pb2+ in perovskite films and reduce the interface charge recombination. The MoS2-grafted MXene interlayer can also tune the energy level of perovskite films and provide an efficient pathway for hole transfer, thereby reducing open-circuit voltage (Voc) deficit and improving device performance. Moreover, the ion diffusion from the perovsikte layer to the carbon electrode is significantly suppressed due to the passivation of perovskite interface defects and the formation of isolation layers by the MoS2-grafted MXene interlayers. As a result, the optimized device exhibits a champion efficiency of 10.70% with an ultrahigh Voc of 1.701 V and significantly improved stability under persistent light irradiation and humidity (80%) for a remarkable 50 day period.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Yang Yang,Wenchao Hu,Fangfang Liu,Aijun Li,Dubin Huang,Ruqiang Zou
Molybdenum disulfide (MoS 2 ) has emerged as a promising anode material for lithium-ion and sodium-ion batteries, yet its practical application is limited by sluggish ion diffusion and low electrical conductivity. Herein, we propose a glucose-assisted hydrothermal strategy that simultaneously enables 1T/2H phase engineering, carbon intercalation, and hierarchical MoS 2 –carbon coupling—forming a “three-in-one” composite structure. The synthesis is achieved using halloysite-derived carbon nanotubes as templates, leading to a 1T/2H-MoS 2 /carbon composite with expanded interlayer spacing and a porous framework. As an anode material, 1T/2H-MoS 2 /C3 delivers outstanding performance, achieving 926.7 mAh g −1 after 100 cycles at 0.2 A g −1 and 544.6 mAh g −1 after 10,000 cycles at 5 A g −1 in lithium-ion cells. In sodium-ion cells, it maintains 403.4 mAh g −1 after 200 cycles at 0.2 A g −1 and 173.5 mAh g −1 after 10,000 cycles at 5 A g −1 . These remarkable enhancements arise from the synergistic effects of the “three-in-one” design, which collectively optimize electronic conductivity, lower ion diffusion barriers, and ensure structural integrity over long-term cycling.
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高影响因子
ELECTROCHIMICA ACTA
·
2017
·
IF 4.798
Niu Huang,Guowang Li,Zhifen Xia,Fang Zheng,Hua Huang,Wenjing Li,Changhua Xiang,Yihua Sun,Panpan Sun,Xiaohua Sun
A low-cost and efficient MoS 2 /graphite paper (GP) counter electrode for dye-sensitized solar cells (DSSCs) is first fabricated by a simple and effective solution processed route. Photo-electric conversion efficiency of 6.48% is obtained for the DSSC adopting MoS 2 /GP, better than the device (6.22%) employing platinized F-doped tin oxide (Pt/FTO) electrode. Because highly conductive GP is performed as a substrate, and the mechanical adhesion and electrical connection between the MoS 2 film and the GP substrate are strong, the series resistance of MoS 2 /GP is much smaller than that of Pt/FTO. A comparable charge transfer resistance of MoS 2 /GP to Pt/FTO is found to be another factor for the better performance. Due to the MoS 2 prepared here possessing relatively high crystallinity and firmly being anchored on the GP substrate, MoS 2 /GP as well exhibits high stability. Hence, excellent electrochemical activity, high stability, facile preparation and low material cost of the MoS 2 /GP electrode offer it a promising potential for large-scale production.
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高影响因子
ACS Sustainable Chemistry & Engineering
·
2024
·
IF 7.1
Jiaxin Liu,Mingdi Pan,Jiuzeng Jin,Yunshu Lu,Zhongmin Feng,Ting Sun
17β-E2 was the most active sterol estrogen and was widely used in animal husbandry for animal fattening and increasing milk production. Its abuse has resulted in residues in the environment. However, even very low concentrations could still enter the human body through the enrichment of the food chain and have adverse effects on the endocrine system. The SERS analysis method was employed in this work for the trace detection of 17β-E2 in environmental water. Cheap Ag NPs were selected as SERS sources. MoS2 provided a platform for the orderly arrangement of Ag NPs while making the material self-cleaning. rGO was coated in the outermost layer and had a protective effect on Ag NPs and could avoid oxidation during storage and use. At the same time, the target molecule could be adsorbed to reduce the distance between itself and Ag NPs, thus enhancing the SERS signal. The material had a high SERS enhancement factor (EF = 1.95 × 107), low detection limit (LOD = 5 × 10–12 M), good linear relationship (R2 = 0.994), good stability (RSD = 4.74%), and strong anti-interference ability. The recovery of 17β-E2 in farm wastewater samples was 100.15–108.00% and RSDs were 1.09–2.57%.
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高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2025
·
IF 11.3
Wei Da,Chi Zhang,Ai-Yong Zhang,Xianhui Yan,Cheng Chen,Lyumeng Ye
Nano zerovalent iron (nZVI) has attracted great interest for the heterogeneous Fenton-like catalysis in environmental remediation due to its high capacity and low cost. However, toxicity and pollution risks arising from the rapid chemical corrosion in the oxygenated aqueous medium largely limit its more practical applications. In this study, the two-dimensionally defective MoS 2 was introduced as the key spatial protector to tailor the electron generation, transfer pathway and utilization efficiency of corrosive charge released from the chemical corrosion of nZVI in aqueous medium during reactions. We rationally designed and controllably prepared the nZVI@MoS 2 hybrid, in which MoS 2 spatially encapsulated nZVI to form the core-shell structure. Fenton-like catalysis on nZVI@MoS 2 produced reactive species to decompose refractory pollutants. Inner nZVI core transferred electrons to PMS through outer MoS 2 shell to activate PMS. Moreover, the MoS 2 shell promoted the Fe(II)/Fe(III) redox-cycling on nZVI and slowed down chemical corrosion of metallic core for superior and sustainable catalysis. Quenching and electron paramagnetic resonance tests indicated the involved hydroxyl radical, sulfate radical, superoxide radical and singlet oxygen with good reusability. Our work provided a new strategy to refine the environmental potential of nZVI benchmark with high industrial importance by two-dimensional transition metal sulfides for the superior environmental Fenton-like catalysis.
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高影响因子
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