JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2017
·
IF 3.012
Mingdang Li,Ping Wang,Fubin Pei,Haoxuan Yu,Peng Chen,Yunhui Dong,Yueyun Li,Qing Liu,Degang Li
In this work, a highly sensitive sandwich-type electrochemical immunosensor was fabricated by using the gold nanorods (Au NRs) as the substrate material and the mesoporous Au@Pd@Pt core-shell nanospheres (m-Au@Pd@Pt) as the label of the detection antibodies (Ab 2 , Ab 2 label) for detecting Hepatitis B surface antigen (HBs Ag). The Au NRs with excellent conductivity and biocompatibility can accelerate the electron transfer on the electrode interface and enhance the load capacity of capture antibodies (Ab 1 ). The m-Au@Pd@Pt with mesoporous structure can not only provide high specific surface area and abundant catalytically active sites, but also offer great pore accessibility of guest species from outside. The detection signal of the immunosensor was effectively improved by the novel Ab 2 label. With the good cooperation between Au NRs and Ab 2 label, a linear relationship between current signal and the logarithm of the HBs Ag concentration was obtained in the wide range of 20 fg/mL to 200 ng/mL and the detection limit of HBs Ag was 6.7 fg/mL (signal-to-noise ratio of 3). Besides, the designed immunosensor shows good reproducibility, long-term stability and high specificity. Crucially, the sensitive and selective response to HBs Ag in real human serum samples confirms that the designed immunosensor will be promising in the clinical diagnosis of biomarkers.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
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2022
·
IF 16.744
Lixiao Zheng,Xinyu Cui,Xuebin Wang,Donghai Xu,Xuebin Lu,Yang Guo
Green production process of high value-added bio-platform compounds is appealing yet challenging due to low catalyst performance and demand for acid or alkali conditions. Herein, we fabricated a tailored bio-tar derived super porous carbon material supported nano Pt catalyst via tuning the alkalinity by nitrogen doping. This novel catalyst realized an enhanced catalytic performance in selective oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA) in alkaline free conditions, in which 97.8 % HMF conversion and 54.7 % FDCA selectivity were achieved under mild temperature (90 °C). The kinetic study revealed that the process is multi-step parallel reactions of 2,5-diformylfuran (DFF) and 5-formylfuran-2-carboxylic acid (FFCA) as intermediates from HMF, and the oxidation of carbonyl group in FFCA is the rate-determining step. This work provides a new synthesis method of low-cost catalyst by using organic waste and inspires a sustainable process for bio-platform compounds production with significant environmental benefits.
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高影响因子
ANALYTICAL SCIENCES
·
2023
·Vol. 39
·期 7
·1129-1142
·
IF 1.6
Jin Yating,Hu Di,Shi Cui,Chen Qianqian,Lu Yanbin,Chen Juanjuan
Abstract In the present work, a potential solid-phase extraction (SPE) material based on graphene anchored with platinum nanoparticles (Pt-Graphene) was prepared and characterized by scanning electron micrographs and transmission electron micrograph. The carbamates residues in fish were enriched by SPE filled with Pt-Graphene and detected by ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). The proposed extraction protocol exhibited satisfactory recoveries (76.5–115.6%), low limit of quantitation values in μg kg −1 level, and good precision for the studied ten carbamates. These results demonstrated the feasibility of the proposed protocol. The developed Pt-Graphene nanoparticles showed excellent performance for extracting analytes at trace levels, indicating that it could be used as a potential SPE sorbent in food residue analysis. Graphical abstract
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PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 31
·14958-14966
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IF 3.925
Liang Shi,Kun Lu,Xiao Kong,Licheng Li,Xiaoli Gu,Junmeng Cai,Xingguang Zhang
Supported Pt catalysts play an important role in selective hydrogenation reactions for upgrading bio-derived chemicals, and they are traditionally prepared by methods such as deposition–precipitation (DP), wet impregnation (WI) and chemical reduction (CR) using NaBH4 and H2 under thermal conditions. This study developed a new reduction method to produce supported Pt NPs on nanofibers, in which Ti3AlC2 (a typical MAX phase) and chloroplatinic acid (H2PtCl6) were employed as raw materials, using as-produced H2 as a reducing agent under hydrothermal synthetic conditions. In the selective hydrogenation of furfural to furfuryl alcohol, the newly-developed catalyst of Pt2.0/Ti3AlxC2Ty exhibited high furfural (FUR) conversion (86.3%) and excellent furfuryl alcohol (FA) selectivity (98.1%) under optimized reaction conditions of 600 rpm, 100 °C, 3 h, and 1 MPa H2 in aqueous media. Moreover, these fibrous catalysts exhibited strong reusability and recyclability for five runs without loss of activity and selectivity.
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高影响因子
Biomedical Optics Express
·
2025
·Vol. 16
·期 5
·2033-2046
·
IF 3.2
Binbin Zeng,Huaiwu Fu,Cong Wu,Xudong Zhang,Tianran Li,Qiong Xu,Yayun Qian,Yayun Qian,Ruirui Yang,Ruirui Yang
In this study, we constructed a SERS assay platform that can be used for the ultrasensitive detection of cerebral infarction (CI)-associated miR-106a-5p based on the recognition competition strategy and the highly efficient catalytic activity of Au@Pt NRs nanoenzymes. When the target miR-106a-5p is present in the detection solution, it binds to the nucleic acid aptamer (cDNA), leading to the detachment of its complementary strand (H1) carrying Au@Pt NRs from the surface of AuNHs, and the oxidation of TMB is reduced, resulting in the decrease of SERS signal. In addition, this method enables single-step, ultrasensitive detection of target miRNAs in patient serum with a limit of detection (LOD) of 0.96 fM, which is consistent with the results of real-time quantitative polymerase chain reaction (qRT-PCR) and fluorescence. This method provides a novel approach for the effective detection of miRNAs, which is of great clinical value for the early detection of CI.
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高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Chunhong He,Hai Luo,Lu He,Xiang Li,Zongde Wang,Shangxing Chen,Yangping Wen,Peng Wang
In this study, we synthesized Fe, N, S co-doped hierarchically porous carbon (Fe-CSK-PCP) with a high specific surface area of 1826.34 m 2 /g and a pore volume of 1.14 cm 3 /g. This material was prepared using discarded lotus seedpods as a carbon source, potassium hydroxide (KOH) as an activator, potassium ferricyanide as both an activator and graphitization promoter, thiourea as a source of N and S dopants, and cetyltrimethylammonium bromide (CTAB) as a pore-enlarging agent. Platinum nanoparticles (PtNPs) were subsequently loaded onto the Fe-CSK-PCP surface via wet impregnation. The enhanced porosity, increased pore size, and heteroatom doping of the Fe-CSK-PCP support have significantly promoted the loading content and dispersion of PtNPs, consequently creating an abundance of active sites. Meanwhile, the hierarchical pore structure has improved the diffusion of analyte and the desorption of oxidation product. Therefore, the fabricated PtNPs/Fe-CSK-PCP sensor exhibited exceptional fouling resistance and electrocatalytic performance in indole-3-acetic acid (IAA) detection, demonstrating a high sensitivity (2.32 μA/μM) and a low detection limit (21.67 nM, S/N = 3) over a wide linear range (0.3–20 μM). This sensor was successfully applied to determine IAA in apple juice samples with satisfactory recoveries.
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高影响因子
MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Xiaoli Luo,Limin Chen,Jianying Yang,Shuting Li,Manting Li,Qian Mo,Yinbao Li,Xinchun Li
Methods that can directly and sensitively quantify a set of correlative substances lack of chromophores in pharmaceuticals are persistently desired. Here, by facile preparation of Pt-Pd nanoparticles/chitosan/nitrogen-doped graphene (N-Gra) nanocomposite, we establish an electroanalytical method for simultaneous detection of ascorbic acid (AA), sulfite and oxalic acid (OA) that are closely involved with Vitamin C injection, a widely-used clinical drug. One-step electrodeposition of Pt-Pd bimetallic nanoparticles on chitosan/N-Gra decorated glassy carbon electrode was proposed to construct a well-performing electrocatalyst possessing notable electrochemical activity to the electrooxidation of both sulfite and OA. The electrocatalytic ability was evidenced by the increased current response and decreased oxidation overpotential. More importantly, sufficiently electrochemical resolution of multiple oxidative peaks allowed simultaneous quantitation of the three species of interest. The peak currents measured by differential pulse voltammetry were linear to the analytical concentration of AA, sulfite, and OA, yielding good linear ranges of 2 ~ 400 μM, 8 ~ 600 μM, and 1.5 ~ 500 μM, respectively. Correspondingly, the limit of detection was 0.97 μM, 5.5 μM, and 0.84 μM. This work opens a vista for multiplex assays of pharmaceuticals, including drug principal ingredient, toxic preservative, and decomposed impurity without chromatographic separation, and thus holds promise for the overall quality control for clinical drug.
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Analytical Methods
·
2019
·Vol. 11
·期 11
·1475-1482
·
IF 2.378
Xiaoyan Mo,Zunyi Wu,Jianfeng Huang,Guangying Zhao,Wenchao Dou
A sensitive and quantitative sandwich electrochemical immunosensor was constructed for the detection of Escherichia coli O157:H7 (E. coli O157:H7) using immune gold@platinum nanoparticles (Au@Pt), neutral red (NR), reduced graphene oxide nanocomposite (rGO) and regenerative leucoemeraldine base polyaniline (PANI)/gold nanoparticles (AuNPs) modified screen-printed carbon electrode (SPCE). The batch production advantages of the SPCE were retained, its disposable characteristic was replaced by the possibility for reuse. The anti-E. coli O157:H7 monoclonal antibody (Ab1) was automatically adsorbed on the SPCE-PANI-AuNPs platform through the amino and AuNPs interaction. rGO-NR-Au@Pt as the non-enzyme signal label can enhance the performance of the immunoassay for the catalytic reduction of H2O2 and amplify the current signal. All characterization steps were monitored by cyclic voltammetry (CV). Based on electrochemical detection of E. coli O157:H7, the linear range was from 8.9 × 103 to 8.9 × 109 CFU mL−1, and limit of detection (LOD) was 2.84 × 103 CFU mL−1. To ensure that the immunosensor can be used repeatedly, ultrasound sonication was used to remove as many surface-bound antibodies as possible. This allows Ab1 to bind to the SPCE-PANI-AuNPs again after the electrode was re-incubated with the antibody solution, and hence, the displacement assay can be repeated and the sensor reused. Furthermore, it was demonstrated that the microchips can be regenerated and reused at least 5 times.
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高影响因子
FUEL
·
2024
·
IF 6.7
Junqian Wang,Yi Wang,Yuqi Wang,Xinyi Li,Caichao Wu,Tianyu Zhang,Bin Tian,Lili Qian,Yang Guo,Le Wu,Lan Zheng,Yanan Li,Xin Ding
Currently, traditional hydrodeoxygenation (HDO) catalysts have various shortcomings such as low activity levels and vulnerability to deactivation. Therefore, a series of MXene-supported Ni-M (M = Pd, Pt, Ru) bimetallic catalysts were designed and prepared. The above catalysts were also comprehensively characterized using XRD, BET, H 2 -TPR, NH 3 -TPD, XPS, SEM and TEM methods. Moreover, due to the largest particular specific surface area, moderate amount of acid sites and the strongest three-electron transfer channels between support and active metals of Ni-Pd/MXene catalyst, it exhibited the superior catalytic performance to achieve 100 % guaiacol conversion and 35.15 % highest overall yields of HDO products (Y HDO ) under the optimal reaction conditions (at 340 °C for 8 h, utilizing in-situ hydrogen source: formic acid). Furthermore, a detailed discussion on the main reaction pathways and mechanism of guaiacol HDO catalyzed by Ni-Pd/MXene was provided, an unique bimetallic synergistic “relay catalytic” theory has been proposed. Kinetic studies revealed that phenol, one of the main HDO products, is primarily generated via guaiacol demethoxylation, while catechol dehydroxylation to phenol acts as the rate-determining step. This work introduces a new strategy for the development of HDO catalysts.
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JOURNAL OF POWER SOURCES
·
2025
·
IF 7.9
Fanghui Wang,Yinlei Li,Yitong Dou,Hong Zhu
In situ polymerization of ethylene dioxythiophene (EDOT) on Keqin Black EC-300 J (CB) to obtain a support (PEDOT@C) with polyethylene dioxythiophene coating on CB. By coating PEDOT on CB, the structural characteristics and surface functionalization degree of CB can be optimized. Then, highly dispersed Pt nanoparticles (NPs, 3–5 nm) was prepared by reducing chloroplatinic acid using an improved sodium borohydride reduction method and loaded onto PEDOT@C to obtain a high loading amount of 40 wt% Pt/PEDOT@C catalyst. The optimization of PEDOT@C structure can strengthen the dispersion of Pt NPs, increase the exposed active sites, thus improve the Electrochemical Active Surface area (ECSA) of Pt/PEDOT@C catalyst (reaching 114.28 m 2 /g), which is 127.5 % and 60.01 % higher than that of JM Pt/C and Pt/CB, respectively. Meanwhile, the Mass activity (MA) of Pt/PEDOT@C catalyst is 0.142 A/mg Pt, which is 38 % and 0.7 % higher than JM Pt/C and Pt/CB, respectively. The stability of Pt/PEDOT@C catalyst is also significantly improved. After accelerated testing, the ECSA loss is 8.33 %, much lower than the 17.33 % and 19.4 % of JM Pt/C and Pt/CB, respectively; the loss of MA is 9.8 %, much lower than the 41.7 % and 18.4 % of JM Pt/C and Pt/CB, respectively. The Pt/PEDOT@C catalyst also has the highest power density (1470 mW/cm 2 ), indicating that the PEDOT modification strategy helps to improve the catalytic performance of the catalyst. The results of this study will promote the development of PEMFCs power sources.
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高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Mengdie Lei,Xilin Ding,Jin Liu,Yinjun Tang,Hongxiang Chen,Yu Zhou,Chengzhou Zhu,Hongye Yan
The urgent need for sensitive and accurate assays to monitor acetylcholinesterase (AChE) activity and organophosphorus pesticides (OPs) arises from the imperative to safeguard human health and protect the ecosystem. Due to its cost-effectiveness, ease of operation, and rapid response, nanozyme-based colorimetry has been widely utilized in the determination of AChE activity and OPs. However, the rational design of nanozymes with high activity and specificity remains a great challenge. Herein, trace amount of Bi-doped core–shell Pd@Pt mesoporous nanospheres (Pd@PtBi2) have been successfully synthesized, exhibiting good peroxidase-like activity and specificity. With the incorporation of trace bismuth, there is a more than 4-fold enhancement in the peroxidase-like performance of Pd@PtBi2 compared to that of Pd@Pt. Besides, no significant improvement of oxidase-like and catalase-like activities of Pd@PtBi2 was found, which prevents interference from O2 and undesirable consumption of substrate H2O2. Based on the blocking impact of thiocholine, a colorimetric detection platform utilizing Pd@PtBi2 was constructed to monitor AChE activity with sensitivity and selectivity. Given the inhibition of OPs on AChE activity, a biosensor was further developed by integrating Pd@PtBi2 with AChE to detect OPs, capitalizing on the cascade amplification strategy. The OP biosensor achieved a detection limit as low as 0.06 ng mL–1, exhibiting high sensitivity and anti-interference ability. This work is promising for the construction of nanozymes with high activity and specificity, as well as the development of nanozyme-based colorimetric biosensors.
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PubMed
高影响因子
Journal of Inorganic and Organometallic Polymers and Materials
·
2020
·Vol. 30
·期 11
·4350-4360
·
IF 1.941
Zhang Zhihua,Peng Xinke,Zhang Zhongping,Xiao Weiming,Deng Shengjun,Mao Xuejin,Hong Sanguo,Chen Chao,Zhang Ning
Metal–organic framework (MOF) supported nanocatalysts are attracting great attentions in heterogeneous catalysis. However, they are still less explored and poorly understood in catalyzing solid–gas reactions. In current work, two MOF supported Pt nanocatalysts were prepared by immersion method coupled with the most commonly used NaBH 4 (Pt/UiO-66-NaBH 4 ) and H 2 (Pt/UiO-66-H 2 ) reduction, and their catalytic CO oxidation performances were investigated. NaBH 4 and H 2 reduction both provide highly dispersed Pt/UiO-66 nanocatalysts, and the two prepared catalysts display excellent CO oxidation activities. Moreover, CO oxidation durability tests reveal that Pt/UiO-66-NaBH 4 shows superior durability and structure stability, which are much better than those of Pt/UiO-66-H 2 . The high structure stability of Pt/UiO-66-NaBH 4 also endows it with good H 2 O and CO 2 tolerance. This work attempts to elucidate the influence of reduction methods on the structures and catalytic CO oxidation performances of Pt/UiO-66 catalysts by employing XRD, TEM, N 2 -sorption, XPS and in situ DRIFTS techniques. Furthermore, the mechanism of CO oxidation was studied by in situ DRIFTS, and the result reveals that the CO oxidation on the two catalysts follows different mechanism.
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高影响因子
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