JOURNAL OF CHEMICAL RESEARCH
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2024
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IF 1
Shunze Gong,Chixiang Yuan,Hang Hu,Defeng Xu
In this work, 20 curcumin derivatives containing halogen atoms or nitrogen atoms were synthesized for suppression of castration-resistant prostate cancer. These curcumin derivatives were prepared by aldol condensation between the substituted benzaldehydes and acetylacetone or ethyl 3-acetyl-4-oxopentanoate. All synthesized compounds were characterized by 1H nuclear magnetic resonance, 13C nuclear magnetic resonance, high resolution mass, ultraviolet–visible spectroscopy, fluorescence spectroscopy, and high-performance liquid chromatography. The in vitro cytotoxicity of the prepared compounds against 22Rv1 cells was evaluated by the standard MTT assay. The compounds with good inhibitory activity against 22Rv1 cells were further tested for androgen receptor suppression effect. The results show that all compounds were successfully prepared and the purities are all over 90%. Among all synthesized compounds, compound p and s exhibit better inhibitory activity against 22Rv1 cells as compared to dimethylcurcumin, compound q and r display similar inhibitory activity against 22Rv1 cells as compared to dimethylcurcumin. Compounds p-s also demonstrate enhanced androgen receptor suppression effect against 22Rv1 cells as compared to dimethylcurcumin. This work indicates that compounds p-s show promising inhibitory activity against castration-resistant prostate cancer cells by suppression of androgen receptor.
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Journal of Energy Storage
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2025
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IF 9.8
Xiangdong Zhu,Xuan Long,Jili Xia,Wei Xu,Xinyou He,Zhimin Xiao,Ke Du,Xing Ou
High‑nickel single-crystal materials hold promise for eliminating grain boundaries and enhancing cycle performance, thereby advancing the development of lithium-ion batteries (LIBs). However, challenges such as cation mixing, poor thermal stability, irreversible phase transition, and serious surface side reactions hinder their commercialization. Hence, we address the above problems by bulk phase Al doping and surface B coating strategies, fabricated the modified cathode LiNi 0.65 Co 0.15 Mn 0.20 O 2 (NCMAB). Benefiting from an excellent dual-effect modification strategy, the cation mixing degree of the NCMAB was effectively controlled, and its cycling performance (25 °C, 1C, 1000 cycles, 82 %) and thermal stability (60 °C, 1C, 250 cycles, 87.6 %) were significantly improved. Notably, visible microcracks and unfavorable phase transitions in the pristine cathode material after cycling were effectively avoided. This further promotes the prospect of high‑nickel single-crystal cathode materials at high temperatures.
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FOOD CHEMISTRY
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2026
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IF 10.4
Tianyu Hu,Fang Zou,Jie Yu,Siqian He,Shiyun Lai,Yuanjie Teng,Zaifa Pan
UNCA employs upconversion nanoparticles as signal probes for specific IGF-1 recognition. • Single-molecule counting enables IGF-1 detection with a low LOD of 6.04 pg/mL. • This method exhibits low cross reactivity and good recovery rates in milk products. There is rapidly growing interest in food nutrition assessment, particularly for nutrients present at low abundance. Here, an upconversion nanoprobe counting analysis (UNCA) is designed for ultra-sensitive detection of insulin-like growth factor-1 (IGF-1). The high sensitivity is attributed to the strong fluorescent intensity of upconversion nanoparticles (UCNPs) and highly specific antibody-antigen binding. Core–shell structured UCNPs are synthesized via co-precipitation followed by layer-by-layer epitaxial growth, and detection probes are constructed through hydrophilic ligand exchange and antibody conjugation. Two detection methods, traditional fluorescent intensity detection and single-molecule counting, are established with linear working ranges of 0.05–5000 ng/mL, which reach limit of detections (LODs) of 21.23 and 6.04 pg/mL, respectively. UNCA is further employed for analyzing three representative milk products, achieving recovery of 73.90%–107.09% with coefficients of variation (CVs) between 2.24% and 7.57%. This method demonstrates quantitative detection of trace-level IGF-1, especially via single-molecule counting. Download: Download high-res image (111KB) Download: Download full-size image
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PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Weitong Wang,Yongdong Tang,Xiaozhe Liu,Bei An,Huijie He,Meijing Cao,Rongzhe Zhao,Yaxuan Chen,Xiaojing Yu,Shengchun Yang,Zhimao Yang,Bin Wang
B N pairs create push-pull coupling to upshift p-band center for optimal *OOH adsorption. • B,N co-doped carbon achieves 99% H 2 O 2 selectivity over wide window in 2e − ORR. • The catalyst yields 788 mmol g cat −1 h −1 H 2 O 2 in H-cell and stable 250 mA cm −2 operation for 14 h. • B N synergy breaks π-conjugation uniformity to enable near-unity 2e − ORR. Selective electrocatalytic two-electron oxygen reduction (2e − ORR) offers a green alternative to the energy-intensive anthraquinone process for hydrogen peroxide (H 2 O 2 ) production. However, the inert π-conjugation of carbon catalysts homogenizes the electronic environment of active sites, making it intrinsically difficult to achieve the optimal *OOH adsorption energy essential for high 2e − selectivity. In this study, we developed B,N co-doped carbon catalysts through a cost-effective pyrolysis method, achieving 99% H 2 O 2 selectivity across a remarkably wide potential window (0.20–0.70 V vs. RHE), an H-cell production rate of 788 mmol g cat −1 h −1 , and sustained operation in a flow cell at 250 mA cm −2 for 14 h with a Faradaic efficiency above 80%. It was demonstrated that engineering adjacent B N pairs within a carbon matrix established a localized push-pull electronic coupling that precisely upshifts the p-band center of active carbon atoms into the theoretically predicted “golden zone” for *OOH adsorption via combined experimental and theoretical analysis. These findings highlight the critical role of heteroatom doping in tailoring electronic structures and provide a scalable strategy for efficient, environmentally friendly H 2 O 2 production using carbon-based catalysts. This work develops B,N co-doped carbon catalysts that achieve 99% H 2 O 2 selectivity and 8 mol g cat −1 h −1 yield via 2e − ORR, leveraging synergistic doping and pyrrolic nitrogen optimization for scalable production. Download: Download high-res image (113KB) Download: Download full-size image
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Xingzhuo Xiong,Zihao Xu,Biao Xu,Chunyu Li,Wubin Dai
Borate-based phosphors have emerged as ideal host materials for near-ultraviolet ( n UV) pumped phosphor-converted white light-emitting diodes (pc- w LEDs) owing to their mild synthesis conditions, broad transparency window, and excellent chemical and thermal stability. Cubic Ba 3 Y 2 B 6 O 15 (BYB) features a highly symmetric lattice structure, providing stable binding sites for rare-earth ions. Its [YO 6 ] octahedral structure allows for controllable lattice distortion, making it an ideal host for multivalent rare-earth luminescent systems. In this study, Ce 3+ , Eu 3+ , Eu 2+ , and Ca 2+ co-doped BYB nanophosphors were prepared in an Ar atmosphere. The partial substitution of Ba 2+ by Ca 2+ promotes the generation of more oxygen vacancies, which in turn induces the self-reduction of Eu 3+ to Eu 2+ . The phosphor exhibits strong absorption characteristics at 365 nm. Acting as an efficient sensitizer, Ce 3+ can simultaneously transfer energy to Eu 2+ and Eu 3+ . By tuning the Ca 2+ content, the Eu 3+ /Eu 2+ ratio and the emission color can be continuously adjusted, achieving a smooth transition from blue-green to orange-red. This Ca 2+ mediated strategy stabilizes the coexistence of Eu 2+ and Eu 3+ , addressing the key limitations of traditional single-phase phosphors. It provides a novel approach for developing high-performance n UV-excited warm white phosphors and demonstrates potential for widespread application in highly efficient pc- w LED devices.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Peiyu Zeng,Renli Fu,Chaoyue Jia,Yifan Lv,Yitao Xue
Sapphire, with its superior optical and thermal properties, is an increasingly attractive high-performance substrate material for advanced LED packaging. However, its inherent surface characteristics-namely the absence of grain boundaries and strong chemical inertness-pose significant challenges for conventional metallization processes, severely limiting its broader application in electronic packaging. To address this critical issue, this study develops a novel silver conductive paste incorporating a custom-designed ZnO–B 2 O 3 –SiO 2 –CuO (ZBSC) glass frit as the inorganic binder. A robust silver thick film was successfully fabricated on a sapphire substrate via a thick-film metallization process. We systematically investigate the effect of sintering temperature on the film's microstructure and properties. The results demonstrate that the ZBSC glass exhibits excellent comprehensive performance and exceptional compatibility with the sapphire substrate. A key finding is the in-situ formation of a spinel CuAl 2 O 4 phase at the interface during sintering, resulting from a chemical reaction between the glass frit and the substrate. This interfacial reaction is crucial for achieving superior bonding. Optimized at a sintering temperature of 850 ℃, the silver film exhibits outstanding comprehensive performance: an ultra-low sheet resistance of 2.03 mΩ/□ and a high shear strength of 21.97 MPa. This performance is attributed to a dense, well-sintered silver microstructure with a continuous and complete conductive network, intimately bonded to the sapphire substrate. This work not only provides a high-performance solution for sapphire metallization but also offers new insights into the role of interfacial chemistry in thick-film technology. The proposed method represents a high-quality, reliable metallization technique with significant promise for advanced electronic packaging applications.
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Nature Communications
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2026
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IF 18.1
Wu Jing,Yang Jingying,Liu Qisijing,Zhang Pixian,Zheng Bowen,Liu Linyuan,An Tingtao,Wang Hao,Xu Fupei,Shen Yudi,Wang Shuo
Characterizing exercise-induced fatigue is challenging due to difficulties in monitoring biochemical and electrophysiological signals consistently. While wearable sensors able to monitor both signals are available, they struggle to maintain stable signal acquisition across exercise-rest scenarios because of significant sweat variation. Here we describe the development of a system, FatigueVisual, combining an adaptive sweat-regulating hybrid electronic textile (e-ASRHT) patch with artificial intelligence (AI) analytics to improve fatigue management. The key innovation lies in the precise regulation of the breakthrough pressure of micropores in fabric electrodes and sweat-excreting areas, allowing for accurate sweat management. This design enables efficient enrichment at an ultralow sweat rate (5.0×10 −4 ml cm −2 min −1 ) while rapidly transporting excess sweat at a rate 2533 times the human physiological limit, ensuring stable chemical-electrophysiological sensing from exercise to rest. A cloud-connected AI model, trained on over 200,000 time-resolved observations collected from 10 participants, recognizes six fatigue-related states and provides personalized exercise management via a mobile app. Validation in three participants showed 87.3% agreement with clinical assessments. The system reduced exercise fatigue by 51.8% and accelerated recovery by 48 h compared with the control group. In practice, FatigueVisual may enable intelligent sports health management.
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CARBOHYDRATE POLYMERS
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2026
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IF 13.2
Wei Tan,Jieyun Zhao,Lei Tan,Yin Tian,Guixiang Song,Ying Chang,Lu Bai,Ping Li,Yuanlin Ren,Xiaohui Liu
The inherent flammability and insufficient ultraviolet (UV) protection of regenerated cellulose fibers limit their functional applications. Inspired by the natural polyphenol–polysaccharide synergy in plants, a lignin-derived boron-containing phenolic network (Lig-BPF) was incorporated into a cellulose spinning system and then coordinated with Zn 2+ to fabricate Cellulose/Lig-BPF@Zn fibers. Compared with pristine cellulose fibers, Cellulose/Lig-BPF@Zn increased the char residue at 800 °C from 13.72% to 30.35% under N 2 atmosphere, and reduced the peak heat release rate by 43.03%. The limiting oxygen index increased from 17.2% to 31.5%, and still remained 29.1% after 20 laundering cycles. TG-FTIR analysis showed an 88.56% reduction in total volatile release intensity, while Raman analysis confirmed an increased degree of graphitization, as evidenced by a decreased I D /I G value from 3.59 to 2.55. Furthermore, the UV protection factor increased from 11.42 to 128.82, and remained 109.74 after durability testing. Mechanistic analyses demonstrate that lignin-derived aromatic domains, boron-containing structures and Zn-coordinated species regulate cellulose pyrolysis and promote the char formation. This work develops a sustainable strategy for converting natural lignin into a bio-based flame retardant that simultaneously improves the flame retardancy and UV protection performance of regenerated cellulose fibers, providing a phosphorus-free and eco-friendly approach for preparing multifunctional carbohydrate-based fibers.
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高影响因子
MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Guoyong Liu,Yanrui Xie,Yanzhen Cao,Yingying Jing
Under the catalysis of MnO 2 , TBHQ can react with Cys to generate fluorescent CDs. • A fluorescence turn-on sensor for detection of TBHQ is proposed based on in-situ formation of fluorescent CDs. • This sensor is capable of quantitatively measuring the concentration of TBHQ in edible oils. Excessive intake of the food additive tert -butylhydroquinone (TBHQ) causes potential hazards to the human body. Designing an easy-to-fabricate and efficient TBHQ sensor is of great research significance. We found that in the presence of MnO 2 , TBHQ can react with cysteine (Cys) to generate fluorescent carbon dots (CDs). Inspired by this simple fluorogenic reaction, a turn-on sensor for TBHQ detection is proposed based on in-situ formation of fluorescent CDs. The sensor offers a linear range of 1–200 μM and a detection limit as low as 0.06 μM. Due to its simple reaction precursors and unambiguous reaction mechanism, this sensor demonstrates good practicability for TBHQ measurement in edible oils. This fluorescence turn-on in-situ sensor, which does not require pre-synthesized materials, offers considerable potential for on-site detection of TBHQ. Download: Download high-res image (122KB) Download: Download full-size image
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JOURNAL OF RARE EARTHS
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2026
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IF 9.6
Biao Xu,Zihao Xu,Chunyu Li,Jian Peng,Xingyu Li,Wubin Dai
Phosphor with thermally stable and highly efficient photoluminescence (PL) is a premise/challenge for use in high-quality phosphor-converted light-emitting diodes (pc-LEDs). Herein, via a facile solid-phase sintering method in air, a negative thermal quenching (TQ) blue emitting SrGa 2 B 2 O 7 (SGB): Bi is reported, mainly associating with the underlying collaborative effect of negative volumetric thermal expansion of rigid host, heterovalent substitution (Bi 3+ → Sr 2+ )-induced V Sr /V O vacancies, and generating self-reduction ions (Bi 2+ ). For charge balance under the condition of temperature rising, both opposite process of self-oxidation (Bi 2+ to Bi 3+ ) and charge release from trap levels can compensate blue-PL loss. This phosphor is comparable to Eu 2+ /Ce 3+ -activated blue-emitting phosphors, and even boasts superior quantum efficiency (QE) and thermal stability. Via artificially codoping Na + for charge compensation, the QE of the SGB:Bi/Na can be further significantly enhanced. Color-tunable PL is achieved via cascade-connected energy transfer (ET) from Bi 3+ to Tb 3+ (green)/Eu 3+ (red) in SGB: Bi/Na/Tb/Eu that possesses high QE/stability than the case of blue/green/red tricolor phosphor blends adopted in warm white LEDs (wLEDs). Finally, the SGB: Bi/Na and SGB: Bi/Tb/Eu/Na are respectively, encapsulated with distinct encapsulants via either traditional or remote “capping” packaging strategy to form blue LEDs and wLEDs, showcasing splendid electroluminescence behaviors and luciferous application prospects.
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JOURNAL OF LUMINESCENCE
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2026
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IF 3.8
Xiao Cheng,Hao Zhang,Zixu Chen,Haozhuo Dong,Ting Yu,Ruifang Guan
Room-temperature phosphorescent carbon dots (RTP-CDs) exhibit exceptional biocompatibility and tunable luminescence but are limited by short lifetimes and exciton quenching. Herein, we develop a one-step pyrolysis strategy using m-phenylenediamine and boric acid to fabricate boron-doped RTP-CDs (M-CDs) with ultralong green afterglow (16 s) and extended lifetime (37.03 ms). The rigid polycrystalline boron oxide matrix effectively confines molecular motion, isolates quenchers, and stabilizes triplet excitons, while boron doping reduces the singlet-triplet energy gap (ΔE ST = 0.206 eV) to promote intersystem crossing (ISC). Further heavy-atom doping (Cl/Br) enhances spin-orbit coupling, boosting afterglow to 18 s and lifetime to 41.16 ms, whereas iodine disrupts the matrix. Leveraging tunable afterglow dynamics, we demonstrate dynamic information encryption with visible/UV-switchable patterns. This work provides a cost-effective route to high-performance RTP-CDs and clarifies synergistic regulation mechanisms for advanced optoelectronic applications.
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MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Zitong Yang,Jingyu Deng,Yili Zhang,Wenkai Qi,Yali Li,Yuxia Zhang
TT-COF/RGO three-dimensional porous structure improves electronic conductivity and stability. • Electrochemical signals are amplified through the electrodeposition of silver nanoparticles. • MIPs achieve highly selective and specific capture of BPA. • A linear range of 0.25–500 nM and a detection limit 0.09 nM. Herein, we developed an electrochemical sensor based on molecularly imprinted polymers (MIPs) for the sensitive detection of bisphenol A (BPA) in food samples. The sensing platform was constructed based on ternary AgNPs/TT-COF/RGO hybrid architecture. Subsequently, a molecularly imprinted polymer (MIP) film was electrodeposited onto the modified electrode using o -phenylenediamine ( o -PD) as the functional monomer and BPA as the template molecule. By integrating the high surface area of RGO, the readily accessible binding sites of TT-COF, and the efficient electron-transfer capability of AgNPs, the ternary AgNPs/TT-COF/RGO hybrid architecture achieves highly sensitive BPA detection. Under optimized conditions, the sensor exhibited a wide linear range of 0.25–500 nM and a low detection limit of 0.09 nM. With its excellent selectivity and sensitivity, the proposed sensor serves as a reliable platform for accurate BPA detection in complex food matrices. We propose an electrochemical sensor based on a MIP/AgNPs/TT-COF/RGO composite for highly selective detection of BPA in complex food samples. The sensor features a tightly integrated composite of RGO and TT-COF, which possesses ordered channels and an electron-rich surface, forming a three-dimensional porous conductive framework that significantly enhances electron transfer efficiency. AgNPs are then electrodeposited onto this framework, leveraging their localized surface plasmon resonance effect and catalytic activity to further amplify the electrochemical response signal at the interface. Finally, the incorporation of MIP enables specific recognition of BPA. Following systematic optimization, the sensor exhibits a broad linear range (0.25–500 nM) and low detection limit (0.09 nM), along with excellent selectivity, reproducibility, and stability. Download: Download high-res image (144KB) Download: Download full-size image
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危险品化学品经营许可证（带存储）