POLYMER INTERNATIONAL
·
2014
·Vol. 64
·期 4
·477-485
·
IF 2.247
Funian Mo,Faxing Zhou,Shaojun Chen,Haipeng Yang,Zaochuan Ge,Shiguo Chen
In this study, a series of shape memory polyurethanes (SMPUs) were synthesized successfully by the bulk polymerization method from liquefied 4,4′-diphenylmethane diisocyanate (L-MDI), 1,4-butanediol (BDO) and polyethylene glycol (PEG). The influence of the hard segment content (HSC) on the structure, morphology, properties and biocompatibility of PEG based SMPUs (PEGSMPUs) was carefully investigated. The results show that a microphase separation structure composed of a semicrystalline soft phase and an amorphous hard phase is formed in the PEG6000/L-MDI/BDO system. Crystallization of the PEG soft segment is influenced by the hard segments. The PEG semicrystalline soft phase serves as a reversible phase while the L-MDI−BDO hard segment acts as physical netpoints. Finally, a cyclic tensile test shows that all PEGSMPUs have good shape recovery (e.g. above 80%), whereas good shape fixity can only be achieved when the HSC is less than 35 wt%. The Cell Counting Kit 8 assay also demonstrates that only PEGSMPUs containing less than 40 wt% HSC have low cytotoxicity. It is thus concluded that PEGSMPUs bearing both good shape memory effects and good biocompatibility can be used as shape memory materials for biomedical applications when the HSC is less than 35 wt%. © 2014 Society of Chemical Industry
研究领域:
材料科学
·
生物医学工程
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高影响因子
POLYMER INTERNATIONAL
·
2014
·Vol. 64
·期 5
·647-653
·
IF 2.247
Ping Liang,Chao-Qun Wang,Hong Chen,Ren-Xi Zhuo,Si-Xue Cheng
A facile strategy for the fabrication of multi-functional polymer/inorganic hybrid nanoparticles for efficient gene and drug co-delivery was developed. A therapeutic gene (p53 plasmid) and a chemotherapy drug (doxorubicin hydrochloride, DOX) were co-loaded simultaneously in hybrid nanoparticles during co-precipitation with high encapsulation efficiency. The prepared heparin–biotin/heparin/CaCO 3 /calcium phosphate/DNA/DOX (HPB/HP/CaCO 3 /CaP/DNA/DOX) nanoparticles exhibited pH sensitivity and tumor-targeting property due to the presence of the CaCO 3 /CaP inorganic component and biotin moiety in the polymer chain, respectively. For comparison, HPB/HP/CaCO 3 /CaP/DOX hybrid nanoparticles for drug delivery were also fabricated. The cell inhibition effects of different nanoparticles on HeLa cells were evaluated using methylthiazole tetrazolium assay. In vitro study indicated that the gene and drug co-delivery system (HPB/HP/CaCO 3 /CaP/DNA/DOX) showed a stronger cell growth inhibition effect as compared with the drug delivery system (HPB/HP/CaCO 3 /CaP/DOX), indicating that HPB/HP/CaCO 3 /CaP/DNA/DOX hybrid nanoparticles could effectively mediate gene transfection and deliver the drug. The hybrid nanoparticles with good biocompatibility have great promise for gene and drug co-delivery. © 2014 Society of Chemical Industry
研究领域:
纳米技术
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药剂学
·
分子生物学
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生物医学工程
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高影响因子
POLYMER INTERNATIONAL
·
2014
·Vol. 64
·期 6
·804-810
·
IF 2.247
Jiming Yang,Ning Zhang,Haolong Li,Bin Xu,Wenjing Tian,Dewen Dong
A facile and efficient strategy for the preparation of polymer grafts on zirconia particles is developed by means of self-initiated photografting and photopolymerization. The UV-induced grafting polymerization is applicable to a variety of polymerizable monomers, allowing the direct formation of homogeneous and stable polymer coatings on zirconia particles without any initiator immobilization. The as-prepared polymer grafts are proved to be efficient supports for polyoxometalates as H 3 PW 12 O 40 can be uniformly and stably immobilized on a poly(4-vinylpyridine) layer through electrostatic interaction. The resulting hybrid catalyst system, associated with high catalytic activity for a series of oxidation reactions such as amines, alkenes, alcohols and sulfides, represents a novel and efficient system with a high catalyst loading capacity and stability upon reuse in further cycles. © 2014 Society of Chemical Industry
研究领域:
材料科学
·
催化化学
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高影响因子
POLYMER INTERNATIONAL
·
2015
·Vol. 64
·期 8
·979-985
·
IF 2.409
Lijuan He,Zongbo Zhang,Xiaogan Yang,Lingling Jiao,Yongming Li,Caihong Xu
A series of liquid polycarbosilanes were successfully synthesized by a sequential Grignard coupling reaction of (chloromethyl)triethoxysilane and vinylmagnesium bromide, followed by reduction with lithium aluminium hydride. The use of non-corrosive, easily handleable and storage stable (chloromethyl)triethoxysilane as starting material is an attractive advantage for this route. The as-synthesized polymers containing Si−CH=CH 2 and Si − H groups are storage stable and can be easily cured in an inert atmosphere. The ceramic yield of the cured polycarbosilane and the C:Si ratio of the derived ceramic were varied by adjusting the mole ratio of starting materials in the feed. Among them, the polymer with a mole ratio of Si−CH=CH 2 to Si − H of 1:10 has the highest ceramic yield at 89.6% after curing at 220 °C and the C:Si ratio of the derived ceramic is 1.48. This kind of polycarbosilane shows high potential as an SiC ceramic precursor in the fabrication of an SiC matrix by the precursor infiltration pyrolysis process. © 2015 Society of Chemical Industry
研究领域:
材料科学
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化学工程
·
无机化学
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高影响因子
POLYMER INTERNATIONAL
·
2017
·Vol. 66
·期 11
·1579-1586
·
IF 2.07
Lanxia Zhao,Xia Zhang,Xin Liu,Juan Li,Yuxia Luan
The synthesis, characterization and potential application in the doxorubicin (Dox) delivery system of a biodegradable polypeptide-based block copolymer, poly(ethylene glycol) 2000 -poly(ϵ-caprolactone) 6000 -poly(glutamic acid) 1000 (PEG 2000 -PCL 6000 -PGA 1000 ), was investigated. The copolymer was synthesized via ring-opening polymerization and characterized by 1 H NMR and Fourier transform IR. The synthesized copolymer could self-assemble into aggregates and the critical aggregation concentration was 0.23 mg mL −1 . Transmission electron microscopy indicated that spherical polymersomes formed with a desirable size about 180 nm. Therefore Dox was encapsulated into these polymersomes, and then we investigated its applications in a drug delivery system. These Dox-loaded polymersomes (PolyDox) were characterized by dynamic light scattering, zeta potential and pH responsiveness measurements. In vitro drug release indicated that the release rate of drug from PolyDox was pH-responsive and significantly decreased. The drug pharmacokinetic parameters were improved in comparison to the group treated with free Dox, which proved the prolonged Dox release from PolyDox. A WST-1 assay indicated a low toxicity and good compatibility of copolymer to cells within 48 h. The results also showed that PolyDox appeared to induce a higher anti-tumor effect. Cell uptake results indicated that PolyDox displayed higher cellular uptake in A549 cells. Endocytosis inhibition results demonstrated that the internalization of PolyDox was mostly mediated by the fluid-phase endocytosis pathway. © 2017 Society of Chemical Industry
研究领域:
药学
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材料科学
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生物医学工程
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癌症研究
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高影响因子
POLYMER INTERNATIONAL
·
2017
·Vol. 66
·期 11
·1530-1537
·
IF 2.07
Xuewen Guo,Xin Liu,Hongying Su,Shaoyun Shan,Qingming Jia
Photoresists involving polymer solubility and degradation play a crucial role in the manufacture of integrated circuits by photolithography. Conventional photoresists typically rely on a single switching mechanism based on a change in either polarity or molecular weight of the polymer. Here we report a new type of poly(olefin sulfone) as a photoresist which overcomes the drawback of poor dry etching resistance, solubility and thermal degradation. The effects of different side-chain groups (acetyl, acetoxy and carboxylic acid) of norbornene on the properties of poly(norbornene sulfone)s were analyzed with the aim of developing a new type of photoresist. Thermogravimetry and gel permeation chromatography results revealed that bond breaking occurred at different temperatures, because of the different side-chain groups, and the three side-chain groups affect the solubility and stability of the poly(norbornene sulfone)s. A novel photoresist material based on a poly(olefin sulfone) with different side-chain groups was synthesized and its physical properties examined. © 2017 Society of Chemical Industry
研究领域:
材料科学
·
化学工程
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高影响因子
POLYMER INTERNATIONAL
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2017
·Vol. 66
·期 11
·1598-1609
·
IF 2.07
Peikun Zhang,Yang Zhou,Hui Su,Hong Lin,Saiqi Tian,Yi Chen,Jun Yan,Yazhou He,Haojun Fan
Despite being extensively implemented in research, it remains challenging but highly desirable to develop ammonium polyphosphate (APP)-based polyurethane (PU) combining excellent flame retardancy and improved mechanical properties. Herein, hydroxyl-decorated APP (OH-APP) was successfully fabricated through a facile, green, yet efficient cation exchange reaction with N -methylethanolamine, and utilized as a multifunctional reinforcing agent for solvent-free two-component PU in the curing process. Results demonstrate that the conjugation of OH-APP imparts to the resultant cured PU samples (PU/OH-APP) enhanced fire safety and smoke suppression performance, as evidenced by the considerable decrease in peak heat release rate, total heat release, peak smoke production rate and total smoke production by 75.4, 30.1, 64.3 and 14.4% over those of pure PU. Furthermore, the tensile strength of PU/OH-APP is improved by 66.5%, while the ductility is well maintained, highlighting its promising potential in industrial applications. This work is aimed at opening a new avenue for the development of APP-based PU with outstanding performances through covalent anchoring approaches. © 2017 Society of Chemical Industry
研究领域:
材料科学
·
化学工程
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高影响因子
POLYMER INTERNATIONAL
·
2017
·Vol. 66
·期 11
·1633-1639
·
IF 2.07
Nafeesa Mushtaq,Lala Rukh Sidra,Guofei Chen,Yongmei Tang,Lubo Xu,Xingzhong Fang
A series of cardo based asymmetric polyimides containing bulky rigid naphthalimide and phthalimide groups were prepared from asymmetric monomer bishaloimide and bisphenols by solution polycondensation. Bishalo(naphthalimide-phthalimide) monomers containing different terminal leaving groups (Cl, F, NO 2 ) were synthesized, and the reactivity difference of these monomers was compared for the successful synthesis of polyimides. The inherent viscosities of the polyimides were in the range 0.51 − 0.60 dL g −1 in N -methyl-2-pyrrolidone at 30 °C. These polyimides demonstrated good organosolubility and mechanical properties with tensile strengths of 93 − 120 MPa, tensile moduli of 3.5 − 5.3 GPa and elongations at break of 2.8% − 4.3%. The polyimides showed high glass transition temperatures ( T g ) ranging from 330 to 363 °C. The 10% weight loss ( T 10% ) of asymmetric polyimides reached 436 − 500 °C in nitrogen and 417 − 476 °C in air. The water uptake of the polyimides was in the range 0.35% − 0.72%. © 2017 Society of Chemical Industry
研究领域:
材料科学
·
高分子化学
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高影响因子
POLYMER INTERNATIONAL
·
2017
·Vol. 66
·期 12
·1827-1833
·
IF 2.07
Jian Zhao,Yanlei Liu,Jianglong Cheng,Shengming Wu,Zhaobo Wang,Haiqing Hu,Chunhua Zhou
Solvent-exfoliated graphene (SEG)-reinforced polystyrene (PS) composites were prepared using a straightforward solution-casting method. SEG sheets, obtained by sonication-assisted solvent direct exfoliation from natural graphite, were well dispersed in the PS matrix as evidenced from scanning electron microscopy and transmission electron microscopy observations. Addition of 0.5 wt% SEG resulted in a 6% increase in tensile strength and a 77% improvement in Young's modulus over pure PS due to the effective load transfer between SEG and PS matrix. The Young's moduli of the PS/SEG composites were obtained from both tensile experiments and calculations using the well-established Halpin–Tsai model. Results from dynamic mechanical analysis indicated that the storage modulus of the PS/SEG composites was significantly improved relative to neat PS. The glass transition temperatures of the composites were found to increase substantially upon addition of SEG, consistent with differential scanning calorimetry analysis. © 2017 Society of Chemical Industry
研究领域:
材料科学
·
复合材料
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高影响因子
POLYMER INTERNATIONAL
·
2018
·Vol. 67
·期 5
·535-543
·
IF 2.352
Yang Hu,Lihui Wang,Jie Shen,Guoqiang Jiang,Chengyou Kan
Using styrene (St) and N , N ′-dimethylaminoethyl methacrylate (DMAEMA) as raw materials, monodispersed P(St- co -DMAEMA) nanoparticles (NPs) were first prepared via semi-continuous emulsion polymerization, and using a stepwise acid–alkali post-treatment, porous P(St- co -DMAEMA) NPs were then obtained and used to adsorb heavy metal ions in aqueous phase. Results showed that the post-treatment conditions including temperature, initial pH and time of acid–alkali treatment had significant effects on the morphology of the porous P(St- co -DMAEMA) NPs, with higher temperature, more extreme pH condition and longer treatment time resulting in larger pores and volume swelling ratio. Under the optimized acid–alkali post-treatment conditions (60 °C, acid treatment at pH = 4.0 for 1 h and then alkali treatment at pH = 10.0 for 1 h), the obtained porous NPs had nearly 15 times the surface area and 1.5 times the amount of surface amino groups than the corresponding solid NPs. An analysis of the mechanism of metal ion adsorption on the porous NPs indicated that the adsorbed amount of metal ions was the result of synergistic effect of physical and chemical adsorption, which was closely related to the porous NP surface area, amount of surface of amino groups and the volume of the ions. © 2018 Society of Chemical Industry
研究领域:
材料科学
·
环境科学
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高影响因子
POLYMER INTERNATIONAL
·
2018
·Vol. 67
·期 5
·598-605
·
IF 2.352
Yongmei Tang,Lan Li,Kai Ma,Guofei Chen,Wei Wang,Xingzhong Fang
Two series of cardo polyimides were prepared from 1,4-bis(4-fluorophthalimide)cyclohexane with different trans / cis ratios and phenolphthalein/ o -cresolphthalein via aromatic nucleophilic substitution reaction. The inherent viscosities of the synthesized polymers were found to be 0.55–0.66 dL g −1 in N , N ′-dimethylacetamide. The cardo polyimides showed excellent solubility in organic solvents, high glass transition temperatures ( T g ) of 275–312 °C and moderate thermal stability with 5% weight loss temperatures ( T d5% ) of 415–441 °C in nitrogen and 370–436 °C in air. The polyimide films exhibited high optical transparency with cut-off wavelengths of 350–355 nm and moderate mechanical properties. The different properties of the polymers caused by trans and cis configurations of 1,4-diaminocyclohexane were also investigated. It was found that with an increasing content of trans configuration of 1,4-diaminocyclohexane in the polyimide backbone, T g of the polyimides increased as well as T d5% , while the solubility gradually decreased. The polyimide films had good optical transparency regardless of trans / cis configuration. © 2018 Society of Chemical Industry
研究领域:
材料科学
·
化学工程
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高影响因子
POLYMER INTERNATIONAL
·
2018
·Vol. 67
·期 6
·700-707
·
IF 2.352
Junsu Jin,Lintao Guo,Chengwei Chang,Hong Meng
The solubility of polystyrene with molecular weight of 100 000 and 260 000 g mol −1 was measured at temperatures from 313 to 333 K and at pressures from 5.0 to 13.0 MPa in subcritical 1,1,1,2-tetrafluoroethane (R134a). The effects of pressure, temperature and molecular weight on the solubility of polystyrene were investigated. Meanwhile, the solubility of polystyrene was correlated using six density-based semi-empirical models (Chrastil, A-L, K-J, S-S, M-S-T and Bartle). The M-S-T model was used to verify the self-consistency of the experimental data, and the enthalpy values of polystyrene, including Δ H total , Δ H sub and Δ H sol , were estimated through the Chrastil and Bartle models. In addition, a modified M-S-T model was proposed through a detailed study of semi-empirical model formulas and verified by the solubility of polystyrene in subcritical R134a and 38 other solid solutes in supercritical carbon dioxide and subcritical R134a. © 2018 Society of Chemical Industry
研究领域:
化学工程
·
材料科学
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DOI
高影响因子
危险品化学品经营许可证（带存储）