JOURNAL OF MEMBRANE SCIENCE
·
2014
·
IF 4.908
Chuanxiong Nie,Lang Ma,Yi Xia,Chao He,Jie Deng,Lingren Wang,Chong Cheng,Shudong Sun,Changsheng Zhao
Nowadays, polymeric membrane based hemodialysis is considered to be the most practical approach for the treatment of kidney failure. To develop advanced hemodialysis membrane integrated with favorable blood and cell compatibilities and efficient blood purification ability, novel biocompatible composite membranes consisting of heparin-mimicking polymer brush functionalized carbon nanotubes (f-CNTs) and polyethersulfone (PES) are designed. Firstly, surface initiated atom transfer polymerization (SI-ATRP) is applied to synthesize heparin-mimicking polymer brush (contained the sodium styrene sulfonate (SS) and methyl ether methacrylate (EGMA) units) grafted CNT. Then, the f-CNT/PES composite membranes are prepared by a liquid–liquid phase separation technique. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) results indicated that the f-CNT would not cause severe damage on the membrane morphologies. Systemic protein ultrafiltration experiment indicated that the heparin-mimicking composite membranes owned satisfied antifouling property and protein rejection ratio. Further blood compatibility evaluation revealed that the composite membranes had decreased protein adsorption, prolonged clotting time, and suppressed platelet adhesion compared to pristine PES membrane. The results of human embryonic hepatocytes (LO-2) culture revealed that the cyto-compatibility of the modified membrane was enhanced by the blending of heparin mimicking polymer functionalized CNT. Furthermore, with the addition of f-CNT, the composite membranes showed remarkably increased removal efficiency of uremic toxin. In general, the fabricated heparin-mimicking f-CNT/PES composite membranes exhibited anti-fouling ability in ultrafiltration, excellent blood and cell compatibility and efficient toxic molecules removal ratio, thus present great potential for various applications, such as hemodialysis and bio-artificial liver support. Furthermore, the proposed method might forward the fabrication of advanced hemodialysis membrane by integrating functional nanomaterials and bioactive polymers.
研究领域:
生物医学工程
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材料科学
·
医学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CONTROLLED RELEASE
·
2016
·
IF 7.441
Yuling Bao,Mingxing Yin,Xiaomeng Hu,Xiangting Zhuang,Yu Sun,Yuanyuan Guo,Songwei Tan,Zhiping Zhang
A pH-sensitive prodrug , TPGS-CH N -DOX, was introduced by conjugating anticancer drug , doxorubicin (DOX), onto d -α-tocopherol polyethylene glycol 1000 succinate (TPGS) via a cleavable Schiff base linkage. The prodrug was mixed with a PEGylated lipid to form a simple but multifunctional hybrid micelle system, which can realize high drug loading capability and biocompatibility , extended blood circulation time, inhibited drug resistance in cancer cells, improved therapeutic response, reduced side effects, and easy functionalities for targeting delivery. The hybrid micelles exhibited in vitro pH-sensitive drug release, enhanced cellular uptake and strengthened cytotoxicity on both drug-sensitive human breast cancer MCF-7 and resistant MCF-7/ADR cells. P-glycoprotein functional inhibition and mitochondria-associated cell apoptosis induced by TPGS were thought to play an important role in overcoming the multidrug resistance . As a result, the hybrid micelles demonstrated good anticancer efficacy in MCF-7/ADR xenograft model. Additionally, after modifying with a tumor-specific targeting peptic ligand, cRGD, the tumor growth/metastasis inhibition was further evidenced in integrin receptor overexpressed melanoma cancer B16F10 and even murine hepatocarcinoma H22 models. This TPGS-based pH-sensitive prodrug provides a safe and “Molecular economical” way in the rational design of prodrugs for overcoming multidrug resistance and targeting delivery, which can improve the potency for clinical use.
研究领域:
药学
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肿瘤学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2021
·Vol. 32
·期 8
·2110782
·
IF 18.808
Qiang Chen,Zhewen Ma,Zhengzhou Wang,Lei Liu,Menghe Zhu,Weiwei Lei,Pingan Song
Recently, soaring developments in microelectronics raise an urgent demand for thermal management materials to tackle their “overheating” concerns. Polymer nanocomposites are promising candidates but often suffer from their inability of mass production, high-cost, poor mechanical robustness, and even flammability. Hence, it is desirable to scalably fabricate low-cost, robust polymeric nanocomposites that are highly thermally conductive and fire-retardant to ensure safe and efficient thermal management. Herein, the scalable production of nacre-like anisotropic nanocomposite films using the layer-by-layer assembly of phenylphosphonic acid@graphene nanoplatelets (PPA@GNPs)-poly(vinyl alcohol) (PVA) layer and GNPs layers, is demonstrated. The PPA serves as interfacial modifiers and fire retardants for flammable PVA (film-forming agent) and GNPs (inexpensive conductive nanofillers) via hydrogen-bonding and π–π stacking. The resultant nanocomposite exhibits a high flexibility, high tensile strength of 259 MPa, and an ultrahigh in-plane thermal conductivity of 82.4 W m -1 K -1 , making it effectively cool smartphone and high-power light emitting diode modules, outperforming commercial tinfoil counterparts. Moreover, the as-designed nanocomposites are intrinsically fire-retardant and can shield electromagnetic interference. This work offers a general strategy for mass production of thermally conductive nanocomposites holding great promise as thermal management materials in electronic, military, and aerospace fields.
研究领域:
材料科学
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电子工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Jiajia Li,Lipeng Yang,Haitao Zhang,Xiaoyan Ji
The Li dendrites introduced by the inhomogeneous Li-ion flux are the barriers to the commercialization of solid-state lithium metal batteries (LMBs). Increasing the Li + transference number and homogenizing the Li + flux are two effective strategies to solve the aforementioned issues. Herein, a flexible composite solid electrolyte (CSE) with an enhanced Li + transference number, high ionic conductivity, and self-healing function was synthesized via a simple template method. Boron nitride (BN) nanosheets with high specific surface area and richly porous structure were used as the passive inorganic filler, homogenizing the Li + flux and facilitating the Li + transmission. The flexible and self-healing features of the CSE reduced the interface resistance and considerably prolonged their cycling life. By exploiting stress–strain curves before and after healing, along with physical characterizations, the self-healing efficiency was obtained and the dendrite suppress mechanisms at the electrode/CSE interface were discussed. Finally, the assembled LiFePO 4 /Li cell with optimized CSE exhibited impressive cycling performance and delivered a steady discharge capacity up to 152 mA h g −1 after 300 cycles at 0.1C. This universal strategy can be used in other emerging energy storage fields to boost high energy density and long cycling life.
研究领域:
材料科学
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电化学
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能源存储
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Pan-Pan Zhao,Peng Lu,Ze-Yong Zhao,Si-Wei Chen,Xing-Yu Li,Cong Deng,Yu-Zhong Wang
Polymeric phase change materials (PCMs) have garnered enduring interest owing to no leakage and considerable latent heat in thermal management. However, the flammability, poor recyclability, and low energy storage density of typical polymeric PCMs have long-term constraint on their applications in sustainable energy. Herein, we fabricated a novel linear polymeric solid–solid PCM (HPPEG-PU) with facile recyclability, fire safety, and simultaneous high heat transition capacity via introducing aromatic Schiff base structure into the hard segment of HPPEG-PU and meanwhile using high-molecular-weight polyethylene glycol as energy-storage soft segment. HPPEG 8000 -PU achieved the latent heat of 131.1 J g −1 , higher than the reported polymeric solid–solid PCMs, and realized thermal reprocessing at 80 ℃ and fire extinguishment once being ignited. Mechanisms for safe, leak-free, and highly efficient thermal energy storage/release were discussed deeply, in which aromatic Schiff base structure induced network confinement, crystallization, and self-crosslinking charring are highly responsible for shape stability, high thermal storage capacity, and fire safety, respectively. Based on the phase change characteristic of HPPEG-PU, thermosensitive imaging and convenient thermal management applications were developed in this work. Cunningly targeting aromatic Schiff base structure to polymeric PCMs may provide a promising route for safe, leak-free, and efficient thermal energy management.
研究领域:
材料科学
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能源管理
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产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Xiaogang Li,Kefan Liu,Yue Yan,Junfeng Yu,Nanxi Dong,Bingxue Liu,Guofeng Tian,Shengli Qi,Dezhen Wu
Separators are applied to segregate cathode and anode, and provide ion transport channels in lithium-ion batteries (LIBs). Nevertheless, present commercial polyolefin separators represent high thermal shrinkage and inferior electrolyte wettability , seriously limiting wider development of LIBs. In this work, we prepared zirconia (ZrO 2 ) nanolayer encapsulated polyimide (PI) nanofiber compound separator through in-situ polar adsorption and hydrolysis strategy. The obtained PI/ZrO 2 compound separator has superior thermal stability, electrolyte wettability and flame retardance in comparison with polypropylene (PP) separator. The shrinkage ratio of prepared PI/ZrO 2 compound separator is 0 even at 300 °C, while the PP separator significantly shrank at 160 °C. Furthermore, the ionic conductivity of PI/ZrO 2 separator reaches up to 1.32 mS cm −1 , far higher than 0.34 mS cm −1 of PP separator. Besides, the coin batteries of LiNi 0.8 Co 0.1 Mn 0.1 O 2 (NCM811)/electrolyte-separator/lithium (Li) assembled with PI/ZrO 2 compound separator exhibit enhanced rate performance, high discharge capacity retention rate of 88.3% after 100 cycles at 1C and excellent battery safety performance even at 140 °C. Thus, combined with its advantages, such as preparation, thermostability, electrolyte wettability, electrochemical property and safety, the PI/ZrO 2 compound separator exhibits promising prospect in the application of commercial LIBs.
研究领域:
材料科学
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能源技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2022
·
IF 9.224
Yu Wang,Xingbao Zhu,Peng Tan,Yuanguo Wu,Zining Man,Xiangyu Wen,Zhe Lü
Solid-state lithium–oxygen batteries (SSLOBs) with high energy density and enhanced safety are promising for green energy storage but plagued by limited O2/Li+/e– triple-phase reaction zone and high internal resistance. Herein, we design and fabricate a novel SSLOB with an integrated cathode and electrolyte structure in which carbon nanotubes were uniformly coated by an in situ-formed hybrid polymer electrolyte (HPE). This interface engineering builds a three-dimensional hybrid electronic and ionic conductor with sufficient void spaces, which facilitates oxygen diffusion and product accommodation and contributes to a significant expansion of the triple-phase reaction zone. The HPE is prepared in situ from poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP), trimethyl phosphate (TMP), and lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) via weak hydrogen bond interactions and shows a flame-resistant property and high electrochemical stability (until 5.4 V). More importantly, it exhibits both a high ionic conductivity (1.08 × 10–3 S cm–1) and high lithium ion transference number (tLi+ up to 0.73) at ambient temperature, promoting uniform Li deposition. In consequence, the battery displays a gravimetric energy density of 542.1 Wh kg–1 (calculated from the weight of the whole device), superior rate performance, and long cycle life (1000 cycles, 167 days). These systems may promote the practical application of SSLOBs in next-generation energy storage.
研究领域:
材料科学
·
能源存储技术
✓ 已验证
产品关联
DOI
高影响因子
Materials Today Energy
·
2021
·
IF 7.311
Qiushi Sun,Xiao Chen,Jian Xie,Changhai Shen,Yuan Jin,Cheng Huang,Xiongwen Xu,Jian Tu,Bo Wang,Tiejun Zhu,Xinbing Zhao,Jipeng Cheng
A solid-state lithium metal battery has been considered as a promising next-generation energy storage system for its high safety. Great challenges remain for the scale-up fabrication of solid-state Li batteries with the current manufacturing facility used for liquid Li-ion batteries. In this work, a scale-up route is employed to fabricate quasi-solid-state Li batteries by cathode-supported coating of a solid electrolyte combined with in-situ polymerization for interfacial modification. A Li 1.3 Al 0.3 Ti 1.7 (PO 4 ) 3 (LATP) layer with a polyvinylidene fluoride (PVDF) binder is coated on the LiCoO 2 cathode as the solid electrolyte. A iquid electrolyte containing a poly(ethylene glycol) methyl ether acrylate (PEGMEA) monomer is injected during the battery fabrication process followed by in-situ polymerization. The in-situ formed gel electrolyte acts as a soft interface to enhance the contact between the electrode and the solid electrolyte. A coin-type quasi-solid-state Li||LiCoO 2 battery delivers a high capacity of 122 mAh g −1 and retains 81% of its initial capacity after 100 cycles at 0.5 C and 60 °C. A pouch-type Li||LiCoO 2 battery is also fabricated using a commercial LiCoO 2 electrode and shows a satisfactory safety performance and stable cycling at 0.5 C.
研究领域:
材料科学
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能源技术
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Zheng Chen,Yun Yang,Qinting Su,Songde Huang,Dakun Song,Rui Ma,Caizhen Zhu,Guanghui Lv,Cuihua Li
An ionogel polymer electrolyte (IGPE), which combines the merits of high ionic conductivity and excellent safety property of a liquid electrolyte and a solid electrolyte, respectively, has shown great prospects in the application of a new generation of lithium secondary batteries. However, the increase in the ionic conductivity of IGPE will inevitably be at the expense of reduced mechanical strength, and this dilemma limits its application and market promotion. Here, an IGPE with a semi-interpenetrating cross-linked network structure was synthesized by UV-cross-linking to tackle this plight. The optimal sample ME82 shows an excellent ionic conductivity of 1.19 mS cm–1 at room temperature and robust mechanical strength (breaking strength: 1.55 MPa, elongation at break: 259%). Therefore, the assembled LiFePO4/ME82/Li cion cell displays an outstanding initial specific discharge capacity of 160.9 mAh g–1 at 55 °C 0.5 C, with a capacity retention of 94.00% after 200 cycles. In addition, ME82-based flexible batteries can withstand bending, folding, and even shearing abuse, which indicates that ME82 has application potentials in flexible electronic devices.
研究领域:
材料科学
·
能源存储
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2023
·
IF 8.7
Bing Liu,Quan Liu,Yucheng Pan,Jianyu Zhou,Junshuo Zhang,Shuai Liu,Ziyang Fan,Huaxia Deng,Yuan Hu,Xinglong Gong
An intelligent material with shear thickening, flame-retardant and sensing properties was prepared by introducing mesoporous silica and carbon nanotubes to ionic liquids. By impregnating the conductive shear thickening fluid (STF) on Kevlar fabric and drying in an oven, CNTs/STF/Kevlar composite was obtained. Due to the rate-sensitive performance of STF, the yarn pull-out force of CNTs/STF/Kevlar increased 3–4 times compared with that of neat Kevlar, once the impregnation weight gain is 55 wt%. Furthermore, the CNTs/STF/Kevlar composite can maintain intact at 110 m/s incident velocity of bullet, whereas neat Kevlar fabric was penetrated at the same velocity, and exhibited the flame resistance as well due to the thermal insulation property of mesoporous silica and flame-retardant performance of ionic liquids. Then, CNTs/STF/Kevlar composite also performed obvious sensing characteristic due to the introducing of carbon nanotubes, and showed the application potential in the field of safe wearable equipment.
研究领域:
材料科学
·
安全工程
·
纺织科学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Haoshan Xu,Shuhong Huang,Jiaqi Qian,Siming Liu,Ling Li,Xiaohui Zhao,Wenming Zhang
Herein, Li 7 La 3 Zr 2 O 12 (LLZO) ceramic nano-networks were introduced by electrostatic spinning into the polyethylene oxide (PEO)/thermoplastic polyurethane (TPU)/LiTFSI matrix (PTL) to constitute novel composite solid electrolytes due to the synergy between the nano-networks and the electrolyte matrix. By adjusting the LLZO nanonetwork with different weight ratios (5 wt%, 10 wt%, and 15 wt%) relative to the total weight of the PEO/TPU/LiTFSI/LLZO (PTLL) composite electrolyte, the electrochemical behavior of the gel electrolyte was optimized. When filled with a 10 wt% Li 7 La 3 Zr 2 O 12 nano-network, the PTLL has a maximum ionic conductivity of 1.33 × 10 −3 S cm −1 at 60 °C and an electrochemical stability window of 5.6 V. Furthermore, the LiFePO 4 /PTLL/Li battery presents an initial specific discharge capacity of 170 mA h g −1 at 0.1 C. After 100 cycles, it demonstrated superior cycle durability at 0.5 C at 60 °C, representing 96.1 % of the initial capacity. These results indicate that the PTLL electrolyte is a promising candidate for advanced solid state lithium batteries .
研究领域:
材料科学
·
能源科学
✓ 已验证
产品关联
DOI
高影响因子
CELLULOSE
·
2023
·Vol. 30
·期 4
·2441-2452
·
IF 5.7
Yi Caifu,Yuan Tianzhong,Ren Hao,Xiao Huining,Zhai Huamin
With the popularity of air fryer, there is an increasing demand for air frying paper. Here, we successfully prepared an air frying paper with good barrier capacity, cytocompatibility and degradability by coating chitosan, zein and lignin containing cellulose nanofibers (LCNFs), in sequence. The obtained triple-coated paper has a high kit number of 12 and a low Cobb 60 value of 4.93 g/m 2 . Importantly, it had excellent hot oil resistance, which was no penetration even at oil temperature of 210 °C. The triple-coated paper also showed good resistance to ethanol, acid and alkali solutions. These excellent barrier capacities were due to the smooth and dense barrier layer formed by chitosan, zein and LCNFs. Thus, the triple-coated paper was successfully used in the air fryer to fry fries and chicken drumsticks. And the good cytocompatibility and degradability of the coated paper further promote its practical application.
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）