Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
·
IF 15.7
Hou Changshun,Guo Junjia,Sun Bonan,Chan Kai Fung,Song Xin,Zhang Li
Natural biological tissues exhibit different mechanical and surface properties. These disparate features make their connections with engineering materials quite difficult due to the lack of universal methods for tuning the interfacial bonding over a wide range. However, the precise control of interfacial properties, including modulus and adhesion on diverse biological tissues, requires overcoming multiple inherent and external barriers. Here we propose an interface-enhanced strategy by spatial and temporal anchoring of magnetic nanostickers for controlled bioadhesive properties. Fully exploiting the interactions from nanostickers by remote control enables the attached patch to achieve extremely high adhesion energy ( ~ 1250 J m -2 ) and interfacial fatigue resistance with a threshold of ~50 J m -2 , at a very low area density of nanostickers (4 μg/mm 2 ). The controlled interfacial properties as well as space and time for anchoring, lead to comprehensively tunable bioadhesion on diverse tissues such as skin, intestine, liver, and kidney, which are strongly desired in biomedical applications. Integration with fragile tissues in female Sprague-Dawley rats for 10 days further demonstrates that the anchored biointerface can adapt to the in vivo environment and promote postoperative recovery. The biointerface bridged by intelligent nanostickers prompts the methodology for bioadhesion towards controllable orientation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Chenxi Liu,Xiao Wang,Xiangze Jia,Wanlin He,Shaobo Zhang,Hongsheng Liu
To meet the demand for nondestructive detection, we developed a truly human-wearable glove biosensor, which can be applied for in-situ analysis of pesticides on crop surfaces during the picking process. Herein, the Burkholderia cepacia (BCL)@UiO-66/Pro functionalized Kevlar-based laser-induced graphene (LIG) three-electrode glove sensing system was equipped with biocompatible semisolid electrolyte. In this system, Kevlar-based LIG electrodes showed the lowest sheet resistance of 28.26 Ω/sq. and I D /I G ratio value of 0.163 with optimal laser power of 9 %. Importantly, the BCL@UiO-66/Pro modified on Kevlar-based LIG electrode enhanced the catalytic efficiency of the BCL, the absolute value of the redox potential increases from the −0.412 V to −0.664 V due to an increase in the immobilization efficiency of BCL on UiO-66 after proline modification. In addition, the Kevlar-based wearable glove biosensor exhibited high repeatability, selective and sensitive electrochemical sensing of MP at concentrations ranging from 5 to 40 μM with a low detection limit of 0.84 μM. During the 10-day storage stability test, the fabricated Kevlar-based LIG biosensor demonstrated good reusability and excellent stability for MP detection with retention of more than 96 % of its initial response. Such wearable Kevlar-based glove biosensor could be a transformative approach for the in-situ analysis of pesticide residue on crops, which could also promote future precision agriculture development.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Wentao Zhu,Fang-Yi Huo,Lei-Ming Cao,Zi-Zhan Li,Qian Zhu,Rongxiang He,Bolei Chen,Yong Liang,Bo Cai,Hong He,Lin-Lin Bu,Ligang Hu
Mimicking natural bio-surfaces with specific microstructures that possess inherent antibacterial ability provides a promising bacteriostatic strategy. However, current methods for biomimetic surface antisepsis can only be implemented on planar substrates made of limited materials. Herein, we developed a 3D printing-based strategy to facilely customize biomimetic microstructures on specified surfaces to successfully enable bacteriostatic function. Two-photon polymerization was employed to fabricate elaborate bacteriostatic microstructures on either flat or curved surfaces regardless of their material (daily-used glass or plastics). Streptococcus mutans were cultured on microstructured surfaces as model bacteria to validate surface bacteriostatic performance. As an example, the strategy was adopted to endow clear aligner substrate surface with bacteriostatic ability, which would enhance the applicability and convenience of these orthodontic devices for maintaining personal oral hygiene. Our strategy will inspire daily or industrial applications aiming at surface sterilization in a customized, convenient, and safe manner.
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Chuanyi Ma,Jian Li,Yi Wang,Zhanguo Li
Hydrogels have attracted widespread attention in the field of surface radioactivity decontamination due to their mild and rapid decontamination processes, as well as their tunable properties. However, fabricating decontamination hydrogels with suitable mechanical properties and environmental adaptability remains challenging. In this study, a tough and freeze-resistant hydrogel (PEAG) was prepared based on graphene oxide (GO), polyvinyl alcohol (PVA), agar (AG), and ethylene glycol (EG) for efficient removal of surface radioactive uranium (VI). Due to the dynamic action of borax and the formation of a nanocomposite dual-network structure, PEAG possesses improved modulus and excellent self-healing properties, allowing the hydrogel to be easily applied to surfaces and to perform operations such as stretching and peeling. In addition, it is found that the PEAG achieves excellent decontamination rates for radioactive uranium (VI) on glass (88.53±1.43 %), stainless steel (86.72±3.41 %), rubber (67.0±2.43 %), ceramics (82.39±1.78 %), and cement (64.52±1.72 %) surfaces, respectively. XPS and contact angle experiments demonstrated that the improved decontamination performance of PEAG is mainly due to the abundant hydroxyl and carbonyl functional groups in the graphene oxide adsorbent, which provide a rich source of complexation sites and enhance its hydrophilic properties for PEAG. Additionally, due to the incorporation of EG, the PEAG hydrogel exhibits good environmental adaptability, which can retain internal moisture and maintain softness and decontamination stability at low temperatures of −20°C. Therefore, PEAG hydrogel is a promising and sustainable candidate material for various surface radioactive decontamination scenarios.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Cleaner Production
·
2024
·
IF 9.7
Chun-dan Gan,Jin-yan Yang,Jiang-fei Li,Meng-qi Yang,Xin-yue Du,Aleksander Nikitin
The continuously elevated concentration of vanadium (V) in the environment is of great concern due to its potential risks to organisms. Microbial reduction is considered a green way to remediate the V-contaminated sites. This study presents the first demonstration of Pseudomonas balearica , a bacterium flourishing in vanadium-titanium magnetite tailings, exhibiting the capacity to reduce pentavalent V [V(V)]. We found that P. balearica exhibited strong tolerance to high V(V) levels, despite lacking known V(V)-reducing genes. After 48 h of incubation, the reduction rates of V(V) by P. balearica under 0.5 mM and 10 mM V(V) stress reached 81.1% and 60.6%, respectively. The phosphorus group and carboxyl group on the bacterial cell surface contributed to V(V) binding and reduction. Both extracellular and intracellular V(V) reduction was significantly facilitated by many critical V-induced differentially expressed genes (DEGs) encoding nitrate/nitrite reductases, ABC transporters , NADH, and c-type cytochromes . In addition, up-regulation of DEGs associated with reactive oxygen species (ROS)-scavenging enzymes , such as glutathione peroxidase, superoxide dismutase , and catalase , was observed as a protective response to oxidative stress triggered by V(V). Moreover, some up-regulated DEGs ( ureC , ureE , ureA , and ureG ) encoding urease subunit or urease accessory proteins significantly enriched in the nickel cation binding pathway, indicating that P. balearica may be resistant to Ni stress by regulating urease activity. This study will help to more thoroughly elucidate the characteristics and mechanisms of V(V) reduction by microbes and provide a native bacterium flourishing in tailings for potential bioremediation of V pollution and bioleaching of V-sources.
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Manyi Yang,Fangzhi Mou,Kang Xiong,Luolin Li,Shuming Zhang,Fuyan Wang,Tianyu Gao,Zixuan Zhao,Jianguo Guan
Hydrazine (N 2 H 4 ) poses severe health risks even in trace amounts due to the highly carcinogenic and teratogenic degeneration while it is frequently used in industrial products. However, current techniques are difficult to perform in-situ detection of N 2 H 4 within confined sophisticated reactors or slim apparatus. Bioinspired by natural plant tumbleweed, we have demonstrated that swarming aggregation-induced emission microrobots (AIE-bots), which have a tumbleweed-like macroporous structure, are capable of performing motile-targeting detection of N 2 H 4 leakage or accumulation. In this protocol, the AIE-bots are assembled from emulsion droplets containing AIEgens and hydrophobic Fe 3 O 4 nanoparticles evenly distributed in CHCl 3 and n-hexane through phase separation during the evaporation of volatile solvents. Upon the application of a precessing B ( t ), the AIE-bots can wobble in swarms and adaptively navigate through narrow channels without adjusting B ( t ). Additionally, they can efficiently ascend steep slopes with angles up to 45° due to the lightweight and coarse surface. While moving, the swarming AIE-bots can in-situ perceive the N 2 H 4 concentration surrounding with an LOD of 3.81 ppb via fluorescence enhancement based on the Schiff base reaction. This work provides a microrobot detecting unknown toxin leakage or accumulation in hard-to-reach microenvironments, and will inspire the development of fluorescent micro-/nanorobots for intelligent motile sensing.
✓ 已验证
产品关联
DOI
高影响因子
Foods
·
2024
·Vol. 13
·期 15
·2385
·
IF 4.7
Mian Wang,Yiting Wang,Muhammad Bilal,Chong Xie,Pei Wang,Xin Rui,Runqiang Yang
Isoflavones, a class of substances with high biological activity, are abundant in soybeans. This study investigated isoflavone biosynthesis in soybean cell suspension cultures under UV-B radiation. UV-B radiation enhanced the transcription level and activity of key enzymes involved in isoflavone synthesis in cell suspension cultures. As a result, the isoflavone contents significantly increased by 19.80% and 91.21% in hypocotyl and cotyledon suspension cultures compared with the control, respectively. Meanwhile, a significant difference was observed in the composition of isoflavones between soybean hypocotyl and cotyledon suspension cultures. Genistin was only detected in hypocotyl suspension cultures, whereas glycitin, daidzein, and genistein accumulated in cotyledon suspension cultures. Therefore, UV-B radiation exhibited tissue-specific regulation of isoflavone biosynthesis in soybean cell suspension cultures. The combination of suspension cultures and abiotic stress provides a novel technological approach to isoflavone accumulation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Liang Liu,Xiaoshuang Zhou,Wei Wang,Kewei Zhang,Xiankai Li,Long Chen,Yanhui Li
Cubic vanadium nitride (VN) holds substantial promise as an anode material for supercapacitors, owing to its high conductivity, theoretical capacity, and a wide negative voltage window. However, the tendency of VN to agglomerate, coupled with poor cycling stability from irreversible volume expansion during charge-discharge cycles, hinders its application in asymmetric supercapacitors. In this work, we reported a one-pot molten salt pyrolysis method to prepare VN/nitrogen doped porous carbon (VN/NPC) materials. The nitrogen-doped carbon material with 3D hierarchical porous structure not only facilitates ion diffusion and charge transport, but also serve as a matrix to in-situ synthesis VN nanoparticles to improve the cycling performance. The VN/NPC exhibits a specific capacitance of 272.3 F/g at 2 mV/s, and 268 F/g at 0.5 A/g. In addition, the VN/NPC demonstrates an excellent cycling stability with only 7 % capacity decay after 10,000 cycles. Furthermore, the all-solid-state asymmetric supercapacitors (ASCs) constructed using VN/NPC as anode and NiCo-layered double hydroxides (NiCo-LDH) as cathode deliver remarkable energy densities of 61.1 and 22.9 Wh/kg at power densities of 700.4 and 7496.6 W/kg, respectively. In addition, this ASCs exhibits excellent cycling stability with 83 % capacity retention after 10,000 cycles. This work provides a green and facile method to prepare anode materials with high capacitance and excellent cycle performance for high energy density ASCs devices.
✓ 已验证
产品关联
DOI
高影响因子
FUEL
·
2025
·
IF 7.5
Qiongqiong He,Zhaoyang Song,Libo Liu,Yuan Xu,Shaomeng Huang,Zhenyong Miao
Butyl xanthates (BX) are the most important agents utilized in the processing of metallic sulfide ores, and residual BX in beneficiation wastewater pollutes the mining environment. In this study, a cobalt carbon composite catalyst (Co@C800-1) was prepared to activate peroxydisulfate (PDS) for the degradation of BX, accompanied by a COD removal rate of up to 97.7% and an extremely high mineralization rate of 91.5%. After six cycles, Co@C800-1 still retained 96% of its catalytic performance. Moreover, this catalytic system demonstrated excellent degradation efficiency (>96 %) within a wide pH range (3–9) and exhibited good salt tolerance (SiO 3 2− and HCO 3 − ). Electron spin resonance analysis suggested that SO 4 − and OH are the main active species, while a small amount of 1 O 2 is present in the Co@C800–1/PDS system. The cobalt particles on the Co@C800-1 surface and the delocalized π-electrons from edge defects are the active sites for generating SO 4 − and OH. The C O groups on the Co@C800-1 surface are the active sites for producing 1 O 2 . Therefore, the synergistic effect of free radical and non-free radical reactions enables the Co@C800-1/PDS system to exhibit excellent degradation performance. The introduction of cobalt ions not only expedites the generation of SO 4 − and OH but also ensures the high stability of Co@C800-1 through cyclic reactions between cobalt ions. This provides a theoretical basis for the development of heterogeneous catalysts for BX degradation.
✓ 已验证
产品关联
DOI
高影响因子
Advanced Healthcare Materials
·
2024
·
IF 10
Chaobo Dai,Zhenghan Shi,Yi Xu,Lingkai Su,Xin Li,Peixue Deng,Hao Wen,Jiahao Wang,Qing Ye,Ray P.S. Han,Qingjun Liu
Bacterial-driven dental caries and tooth discoloration are growing concerns as the most common oral health problems. Current diagnostic methods and treatment strategies hardly allow simultaneous early detection and non-invasive treatment of these oral diseases. Herein, a wearable multifunctional double network hydrogel combined with polyaniline and barium titanate (PANI@BTO) nanoparticles is developed for oral microenvironment visualized sensing and sonodynamic therapy. Due to the colorimetric properties of polyaniline, the hydrogel displays a highly sensitive and selective response for visualized sensing of oral acidic microenvironment. Meanwhile, the barium titanate in the hydrogel efficiently generates reactive oxygen species (ROS) under ultrasound irradiation, realizing non-invasive treatment in the oral cavity. Through bacterial elimination experiments and tooth whitening studies, the hydrogel can achieve the dual effect of effectively inhibiting the growth of cariogenic bacteria and degrading tooth surface pigments. Owing to the visualized sensing of the oral acidic microenvironment and efficient sonodynamic therapy function, the proposed hydrogel system offers a solution for the prevention of caries and tooth whitening, which is promising in developing the biomedical system targeting the simultaneous sensing and therapy for oral diseases.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Plants-Basel
·
2024
·Vol. 13
·期 18
·2576
·
IF 4
Yiqun Hu,Qingqing Chen,Aifang Zhang,Liyuan Zhang,Hansong Dong
Small non-coding RNAs (sRNAs) are pivotal post-transcriptional regulatory factors influencing biological activity. Studies on the rice bacterial blight pathogenXanthomonas oryzaepathovaroryzaestrain PXO99A, previously identified a virulence-associated sRNA, trans3287. A mutant strain lacking this sRNA, named SK01, resulted in markedly diminished virulence towards rice. This study aims to further elucidate the underlying bacterial virulent function of trans3287. The expression of trans3287 was quantified in virulence-inducing and standard nutritional conditions to clarify its production mechanism. The detection of virulence-associated genes revealed that trans3287 regulated the synthesis processes of extracellular polysaccharides, lipopolysaccharides, and the type III secretion system. Moreover, bioinformatics prediction and quantitative PCR indicated a potential direct target of trans3287,PXO_03470, encoding cardiolipin synthase. A dual-plasmid system fusing with GFP tag and protein immunoblotting confirmed that sRNA trans3287 negatively regulatedPXO_03470. Bacterial biofilms demonstrated trans3287 regulated the disruption of biofilm integrity through cardiolipin synthase. This study provides preliminary insights into the mechanistic underpinnings of the role of sRNA trans3287 in mediating bacterial virulence through cardiolipin synthase.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2025
·
IF 8.4
Zhixiang Xu,Caiqing Li,Jinrui Xiong,Siyuan Hu,Yitao Ma,Siyuan Li,Xiaomin Ren,Bin Huang,Xuejun Pan
Antibiotic resistance genes (ARGs) have become a major focus in environmental safety and human health, with concerns about non-antibiotic substances like microplastics facilitating their horizontal gene transfer. Phthalate esters (PAEs), as ubiquitous plastic additives, are prevalent in aquatic environments, yet there remains a dearth of studies examining their impacts on ARG dissemination. This study focuses on dibutyl phthalate (DBP), a prototypical PAE, to assess its potential influence on the conjugative transfer of ARGs along with the related molecular mechanisms. The results revealed that DBP exposure at environmentally relevant concentrations significantly promoted the conjugative transfer of RP4 plasmid-mediated ARGs by up to 2.7-fold compared to that of the control group, whereas it severely suppressed the conjugation at a high concentration (100 μg/L). The promotion of conjugation transfer by low-concentration DBP (0.01–10 μg/L) was mainly attributed to the stimulation of ROS, enhanced membrane permeability, increased energy synthesis, increased polymeric substances secretion, and upregulation of conjugation-related genes. Conversely, high DBP exposure induced oxidative damage and reduced ATP synthesis, resulting in the suppression of ARG conjugation. Notably, donor and recipient bacteria responded differently to DBP-induced oxidative stress. This study explores the environmental behavior of DBP in the water environment from the perspective of ARG propagation and provides essential data and theoretical insights to raise public awareness about the ecological security risks of PAEs.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）