JOURNAL OF POLYMER RESEARCH
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2024
·Vol. 31
·期 9
·1-11
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IF 2.6
Liu Xiang,Ni Zecheng,Li Weiyi,Wang Ping
With the rapid development of smart devices and wearable electronic products, there is an increasing demand for flexible, durable, and high-performance energy storage systems. Supercapacitors (SCs) have become strong candidates for the next generation of energy solutions due to their excellent power density, rapid charge and discharge capabilities, and long cycle life. However, the limitations of existing electrolytes in terms of high ionic conductivity, mechanical strength, and stability under extreme conditions have restricted the development of SCs. This study has developed a new type of dual-network hydrogel-polymer electrolyte (DNHPE) based on polyvinyl alcohol (PVA), polyacrylamide (PAM), Lithium bistrifluoromethanesulfonimidate (LiTFSI), and 1-ethyl-3-methylimidazolium tetrafluoroborate ([EMIM][BF 4 ]), to enhance mechanical performance and ionic conductivity. The DNHPE-1 exhibits outstanding ionic conductivity (9.34 S m −1 ), stretchability (650%), and thermal stability, which are crucial for the development of SCs and wearable sensors. In addition, the high strain sensitivity of the DNHPE-1 makes it an ideal material for strain sensors, capable of accurately monitoring various human movements. The research results show that the supercapacitor (SC) based on DNHPE-1 can operate effectively under different environmental conditions, demonstrating its broad application prospects in flexible, wearable smart devices.
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Nature Communications
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2024
·Vol. 15
·期 1
·1-17
·
IF 14.7
Zheng Botuo,Zhong Liling,Wang Xiaoxiao,Lin Peiyao,Yang Zezhou,Bai Tianwen,Shen Hang,Zhang Huagui
Inverse vulcanization exploits S 8 to synthesize polysulfides. However, evolution of products and its mechanism during inverse vulcanization remains elusive. Herein, inverse vulcanization curves are obtained to describe the inverse vulcanization process in terms of three stages: induction, curing and over-cure. The typical curves exhibit a moduli increment before declining or plateauing, reflecting the process of polysulfide network formation and loosing depending on monomers. For aromatic alkenes, in the over-cure, the crosslinked polysulfide evolves significantly into a sparse network with accelerated relaxation, due to the degradation of alkenyl moieties into thiocarbonyls. The inverse vulcanization product of olefins degrades slowly with fluctuated relaxation time and modulus because of the generation of thiophene moieties, while the inverse vulcanization curve of dicyclopentadiene has a plateau following curing stage. Confirmed by calculations, the mechanisms reveal the alkenyl groups react spontaneously into thiocarbonyls or thiophenes via similar sulfur-substituted alkenyl intermediates but with different energy barriers.
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
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2025
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IF 1.6
Tian Duan,Wang Zhe,Zhang Jiaqian,Luo Ying,Zhang Zhenlong,Li Chao,Ye Kai,Peng Chaoliang,Chen Yiming,Lin Wenxue,Zhang Jingyan
This study examines attapulgite-bentonite-pyrite (AB 7 Fe) and zeolite-bentonite-pyrite (ZB 7 Fe) mixtures as buffer and backfill materials for nuclide migration using soil column experiments and COMSOL modeling. The results indicated that ZB 7 Fe possessed higher adsorption capacities for cesium (Cs) and strontium (Sr) compared to AB 7 Fe. Conversely, AB 7 Fe demonstrated superior retardation performance, more effectively slowing nuclide migration. After 1000 years, Cs and Sr concentrations in AB 7 Fe surpassed those in ZB 7 Fe. Additionally, nuclide migration increased with higher initiation pressure, dispersion, and diffusion coefficients. This research is crucial for improving the long-term safety of nuclear waste repositories.
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JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
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2025
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IF 3.2
Liu Hongli,Peng Ziyang,Yuan Wenjin,Zhang Baojie,Chu Peng,Liu Yuhao,Xie Weiqiang,Tao Bingxin,Song Yao,Zu Wenjing,Yu Kun,Bian Chenghao
Mullite fiber aerogels are suitable for high-temperature insulation and other extreme environment applications due to their low density, excellent thermal stability, and low thermal conductivity. However, the elevated thermal conductivity at high temperatures and the limited mechanical strength confined its wider application. In this paper, mullite fibers/silicon carbide (SiC) composite aerogels were prepared by freeze-drying method with polycarbosilane (PCS) as a precursor. The SiC formed during the pyrolysis of PCS served as a high-temperature binder, which can form a tough three-dimensional network structure with mullite fibers. Benefit from the good infrared shielding property and high strength of SiC phase, the high-temperature insulation and mechanical properties of the aerogels were greatly improved. The lowest thermal conductivity of the mullite fibers/SiC aerogel can be 0.037 W·m −1 ·K −1 at room temperature and 0.067 W·m −1 ·K −1 at 1000 °C. Meanwhile the compressive strength can reach 0.31 MPa (10% strain). These favorable properties make it a very promising material in high temperature insulation applications. Graphical
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Nature Communications
·
2024
·Vol. 15
·期 1
·1-17
·
IF 14.7
Huang Yanli,Wan Xufeng,Su Qiang,Zhao Chunlin,Cao Jian,Yue Yan,Li Shuoyuan,Chen Xiaoting,Yin Jie,Deng Yi,Zhang Xianzeng,Wu Tianmin,Zhou Zongke,Wang Duan
Implant-associated infections due to the formation of bacterial biofilms pose a serious threat in medical healthcare, which needs effective therapeutic methods. Here, we propose a multifunctional nanoreactor by spatiotemporal ultrasound-driven tandem catalysis to amplify the efficacy of sonodynamic and chemodynamic therapy. By combining piezoelectric barium titanate with polydopamine and copper, the ultrasound-activated piezo-hot carriers transfer easily to copper by polydopamine. It boosts reactive oxygen species production by piezoelectrics, and facilitates the interconversion between Cu2 + and Cu + to promote hydroxyl radical generation via Cu + -catalyzed chemodynamic reactions. Finally, the elevated reactive oxygen species cause bacterial membrane structure loosening and DNA damage. Transcriptomics and metabolomics analysis reveal that intracellular copper overload restricts the tricarboxylic acid cycle, promoting bacterial cuproptosis-like death. Therefore, the polyetherketoneketone scaffold engineered with the designed nanoreactor shows excellent antibacterial performance with ultrasound stimulation and promotes angiogenesis and osteogenesis on-demand in vivo.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-12
·
IF 15.7
Zhang Jie,Liu Yong,Dittrich Thomas,Wang Zhuan,Ji Pengxiang,Li Mingrun,Ta Na,Zhang Hongyan,Zhen Chao,Xu Yanjun,Li Dongfeng,Feng Zhendong,Li Zheng,Luo Yaling,Cui Junhao,Su Dong,Weng Yuxiang,Liu Gang,Wang Xiuli,Fan Fengtao,Li Can
Charge separation is a critical process for achieving high photocatalytic efficiency, and ferroelectrics hold significant potential for facilitating effective charge separation. However, few studies have demonstrated substantial photocatalytic activity in these materials. In this study, we demonstrate that in ferroelectric PbTiO 3 , surface Ti vacancy defects near the positively polarized facets impede photocatalytic performance by trapping electrons and inducing their recombination. To tackle this issue, we selectively grew SrTiO 3 nanolayers on the polarized facets PbTiO 3 , effectively mitigating interface Ti defects. This modification establishes a efficient electron transfer pathway at the interface between the positively polarized facets and the cocatalyst, extending the electron lifetime from 50 microseconds to the millisecond scale and significantly increasing electron participation in water-splitting reactions. Consequently, the apparent quantum yield for overall water splitting achieves the highest values reported to date for ferroelectric photocatalytic materials. This work provides an effective strategy for designing advanced ferroelectric photocatalytic systems.
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RARE METALS
·
2025
·
IF 11
Guo Jing,Mu Zhi-Mei,Yu Jing,Sun Guan-Liang,Hou Lin-Rui,Qiao Xue-Zhi,Yang Shi-Kuan,Zhang Xing-Shuang,Xu Guan-Chen,Liu Guo-An,Yang Fan,Yuan Chang-Zhou,Liang Xiu
Metal–organic framework materials exhibit considerable potential as molecularly selective surface-enhanced Raman spectroscopy (SERS) substrates because of their microporous structures, which enrich small molecules while excluding larger ones. In this study, we develop a template-assisted chemical-etching strategy to prepare layered tuneable SERS substrates based on hierarchical porous zeolitic imidazolate framework-67 (HP-ZIF-67) with a rhombic dodecahedral structure. The synergistic SERS enhancement mechanisms of HP-ZIF-67, which combine electromagnetic (EM) and chemical (CM) effects, were systematically studied through numerical simulations and experiments. Calculations revealed that under 633-nm laser excitation, the contributions of the EM and CM effects to the total SERS enhancement factor of HP-ZIF-67 were 60% and 40%, respectively. The hierarchical porous structure enhanced the fluid-flow flux over the microporous ZIF-67 because the increased pore radius reduced the viscous resistance and facilitated rapid molecular transport through the interconnected macro-meso-channels. Precise modulation of the CM and EM effects, combined with enhanced mass transfer, facilitated the development of HP-ZIF-67 and HP-ZIF-67@Au as efficient SERS sensors. An investigation of the relationship between pore-size distribution and EM effects revealed the pivotal role of light confinement by whispering-gallery-mode microcavities in enhancing the SERS performance. The optimised HP-ZIF-67@Au composites functioned as flexible and highly sensitive in situ SERS sensors for gases and liquids, including volatile organic-compound gas and liquid-pesticide residues. This study introduces a novel design concept and provides a robust theoretical foundation for the future development of exhaled-breath point-of-care diagnostic devices and sweat-based wearable biomedical sensors. Graphical abstract
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Communications Chemistry
·
2025
·Vol. 8
·期 1
·1-12
·
IF 6.2
Bai Si-Cong,Wang Ye-Cheng,Ye Wei-Lin,Wu Sheng-Yen,Jia Lee,Hong Liu,Xie Huan-Zhang,Li Gao
Abnormal amyloid beta (Aβ) aggregation is a key factor in Alzheimer’s disease (AD) pathology. Despite efforts to develop Aβ aggregation inhibitors, efficient screening strategies remain limited. Here, we initially applied structure-based virtual screening to target Aβ fibril ends, aiming to identify compounds that could effectively combat AD neurodegeneration. Using this approach, we screened a traditional Chinese medicine library with thousands of compounds, and selected high-scoring hits likely to inhibit fibril elongation or promote fibril depolymerization. Forsythoside A emerged as the most potent inhibitor, effectively reducing Aβ 40 aggregation and disassembling pre-formed fibrils, as confirmed through biophysical assays and surface plasmon resonance analysis. Chemical kinetics further elucidated its inhibitory mechanism. In Caenorhabditis elegans , forsythoside A alleviated Aβ-induced toxicity and extended the lifespan of the AD transgenic models. Further virtual screening and experimental validation using a CNS-penetrant compound library confirmed the robustness of our strategy. Our study underscores the effectiveness of virtual screening in the identification of Aβ aggregation inhibitors and emphasizes the critical significance of targeting fibril ends.
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Neuroscience Bulletin
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2025
·
IF 5.8
He Junqiu,Sun Shan,Wang Hongfeng,Ying Zheng,Tam Kin Yip
Alzheimer’s disease (AD) poses one of the most urgent medical challenges in the 21st century as it affects millions of people. Unfortunately, the etiopathogenesis of AD is not yet fully understood and the current pharmacotherapy options are somewhat limited. Here, we report a novel inhibitor, Compound 44, for targeting cholinesterases, amyloid-β (Aβ) aggregation, and glycogen synthase kinase 3β (GSK-3β) simultaneously with the aim of achieving symptomatic relief and disease modification in AD therapy. We found that Compound 44 had good inhibitory effects on all intended targets with IC 50 s of submicromolar or better, significant neuroprotective effects in cell models, and beneficial improvement of cognitive deficits in the triple transgenic AD (3 × Tg AD) mouse model. Moreover, we showed that Compound 44 acts as an autophagy regulator by inducing nuclear translocation of transcription factor EB through GSK-3β inhibition, enhancing the biogenesis of lysosomes and elevating autophagic flux, thus ameliorating the amyloid burden and tauopathy, as well as mitigating the disease phenotype. Our results suggest that triple-target inhibition via Compound 44 could be a promising strategy that may lead to the development of effective therapeutic approaches for AD.
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Science China-Chemistry
·
2025
·
IF 9.7
Qiu Zhuo,Dai Yiqi,Zhang Runzhi,Xiao Xin,Tong Yuqiao,Yao Lihua,Yan Dongpeng
Cost-effective metal-based electrocatalysts are desirable for industrial water and seawater electrolysis, triggering the hydrogen evolution reaction (HER) with high efficiency. Here, we report the loading of ultralow-content Ru-Os dual-atom onto NiCoP nanoneedles significantly enhancing HER in seawater splitting. The localization of 0.16% Ru and 0.58% Os atoms within NiCoP induces changes in the electronic structure and coordination environment of the Ni active sites. This catalyst achieves low overpotentials (29 and 303 mV in alkaline solution, 68 and 331 mV in alkaline seawater) at 10 and 800 mA/cm 2 , respectively, demonstrating remarkable stability by maintaining performance at 500 mA/cm 2 for 24 h in alkaline and simulated seawater. Experimental and theoretical studies indicate that ultralow content Ru and Os dual atoms are immobilized on the surface of NiCoP/NF through Ru-P and Os-P bonds, leading to electron transfer and changes in the coordination environment. These results enhance the activity of Ni active sits on support, demonstrating superior HER performance in alkaline solution and seawater. Ultralow content Ru and Os dual atoms in NiCoP@Ru-Os/NF play a crucial role in reducing the Gibbs free energy of hydrogen adsorption and lowering the d -band position of the catalyst, thereby accelerating the HER kinetic.
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npj Biofilms and Microbiomes
·
2025
·Vol. 11
·期 1
·1-14
·
IF 9.2
Zhang Song-xia,Hu Fang-fang,Chen Huan,Guo Jing,Xiang Zhong-wen,Ding Xin,Ye Meng-ling,Ye Wen-li,Chen Jun-hong,Wang Xin,Han Wen-jing,Zhou Hong-hao,Zhang Wei,Huang Yun,Wu Lie-lin,Lian Guang-hui,Chen Yao
Drug tolerance is clinically common but its mechanism is unclear. Previous studies found RSV tolerance in ALD treatment. This study explores mechanisms involving gut bacteria and host factors. Male C57BL/6J mice were induced into ALD with the Lieber-DeCarli alcohol diet, then ALD-RSV group mice were gavaged RSV (150 mg/kg/day) for 5 weeks. Throughout the experiment, ALD and ALD-RSV mice were on the Lieber-DeCarli alcohol diet, while the Vehicle group received a control diet. By week 5, tolerance to RSV efficacy emerged, with markedly reduced RSV exposure at the final dose. ALD-RSV group exhibited increased levels of Eggerthella lenta ( E.lent ), which metabolizes RSV into dihydroresveratrol (DHR). Chronic RSV treatment upregulated UGT1A1, the enzyme converting RSV into its primary metabolite, trans-resveratrol-3-O-β-D-glucuronide (R3G). The synergy between gut bacteria and host factors enhances RSV metabolism in ALD mice, driving tolerance and offering insights into other clinical drugs tolerance mechanisms.
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JOURNAL OF POROUS MATERIALS
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2025
·
IF 3.2
Han Minhang,Hao Mingyuan,Li Zhuohang,Jian Sihao,Ma Chao,Miao Yang
In recent years, ceramic fiber aerogel have been one of the most attractive insulating materials due to its low thermal conductivity, excellent mechanical properties and heat resistance. However, the high radiation heat transfer limits its practical application at high temperatures. In this study, a novel SiO 2 -ZrO 2 fiber aerogel/TiO 2 composite (SZTFAs) was successfully designed and prepared through an air-assisted electrospinning technique in conjunction with the hydrolysis of TiCl 4 . The SZTFAs exhibits anatase TiO 2 nanocoating on the fiber surface. The SZTFAs have low density (14 mg/cm 3 ), good mechanical properties (up to 80% compressive strain, 105.6 KPa), excellent high temperature stability (1200 °C) and fatigue resistance (after 1000 cycles, the maximum stress and Young’s modulus of the SZTFAs remain above 60%) and low thermal conductivity (0.0292 W/(m·K)). After 10 min of exposure to a butane flame, the backside temperature of the SZTFAs was 165 °C, which was approximately 40 °C lower than that of the samples without added TiO 2 . Due to the porous layered three-dimensional structure of SiO 2 -ZrO 2 fibers aerogel and TiO 2 nanolayer with shielding infrared radiation, the SZTFAs exhibit excellent heat resistance and thermal insulation properties. This study provides a method for developing ceramic fiber aerogels with excellent thermal insulation and mechanical properties at high temperatures.
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