Small
·
2018
·Vol. 14
·期 7
·1702431
·
IF 9.598
Jianhua Liu,Longhai Jin,Yinghui Wang,Xing Ding,Songtao Zhang,Shuyan Song,Daguang Wang,Hongjie Zhang
Design of new nanoagents that intrinsically have both diagnostic imaging and therapeutic capabilities is highly desirable for personalized medicine. In this work, a novel nanotheranostic agent is fabricated based on polydopamine (PDA)-functionalized Co-P nanocomposites (Co-P@PDA) for magnetic resonance imaging (MRI)-guided combined photothermal therapy and chemotherapy. The ultrahigh relaxivity of 224.61 m m −1 s −1 can enable Co-P@PDA to be applied as an excellent contrast agent for MRI in vitro and in vivo, providing essential and comprehensive information for tumor clinical diagnosis. Moreover, Co-P@PDA exhibit excellent photothermal performance owing to the strong near-infrared (NIR) absorbance of both Co-P nanocomposite and PDA. Highly effective ablation of tumors is achieved in a murine tumor model because the NIR laser not only induces photothermal effects but also triggers the chemotherapeutic drug on-demand release, which endows the Co-P@PDA with high curative effects but little toxicity and few side effects. These findings demonstrate that Co-P@PDA are promising agents for highly effective and precise antitumor treatment and warrant exploration as novel theranostic nanoagents with good potential for future clinical translation.
研究领域:
纳米医学
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诊疗一体化
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癌症治疗
·
分子影像
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生物医学工程
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DOI
高影响因子
Journal of Energy Storage
·
2026
·
IF 10.7
Mengyao Li,Liangtao Yang,Xinyao Bian,Hailiang Cao,Min Zhao,Peizhi Liu,Zhi Zheng,Wei Deng,Junjie Guo
The practical implementation of lithium‑sulfur (Li - S) batteries is critically hindered by the polysulfide shuttle effect and the sluggish conversion kinetics of lithium polysulfides (LiPSs). Herein, we design a freestanding interlayer comprising bimetallic phosphide nanoparticles embedded within interconnected porous carbon nanofibers (NiCoP@PCNF). In this architecture, the conductive PCNF skeleton functions as a physical barrier and facilitates rapid electron/ion transport, while the polar NiCoP nanoparticles serve as robust chemical anchors for LiPSs. Notably, density functional theory calculations and electrochemical analyses reveal that NiCoP acts as an efficient electrocatalyst by modulating its d-p band center, which optimizes electron transfer and substantially accelerates the liquid-solid conversion of LiPSs. Benefiting from this synergistic adsorption-catalysis effect, Li-S cells equipped with the NiCoP@PCNF interlayer deliver outstanding electrochemical performance, including a high initial capacity of 1652 mAh g −1 at 0.1C, an excellent rate capability of 1013 mAh g −1 at 2C, and exceptional cycling stability with a retained capacity of 757 mAh g −1 after 200 cycles at 3.0C. This work highlights a strategic design for multifunctional interlayers through the integration of conductive carbon frameworks with bimetallic phosphides, offering a promising pathway toward high-performance Li-S batteries.
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DOI
高影响因子
AQUATIC TOXICOLOGY
·
2026
·
IF 4.6
Yijie Zhang,Jiyuan Wang,Jialu Xu,Hairun Li,Xinyi Fei,Ruke Wang,Yuqing Shao,Yuhao Miao,Hao Wu,Yuzi Zhou,Huiliang Zou,Lailing Du,Xiaofen Zhang,Xiaodong Yao,Hongyu Li
p -Aminophenol (PAP) is an important intermediate in the synthesis and environmental degradation of acetaminophen, and it is widely found in pharmaceutical and dyeing wastewater. However, systematic studies on its toxicity to freshwater invertebrates remain limited. In this study, Biomphalaria glabrata was used as a model organism to comprehensively evaluate the acute and chronic toxicity of PAP across three developmental stages (embryo, juvenile, and adult stages) and to identify key target organs of damage through histopathological analysis. Acute toxicity tests revealed a clear stage-dependent sensitivity gradient, with embryos being the most sensitive (216 h LC 50 = 4.16 mg/L, 95% CI = 3.94 to 4.39 mg/L), followed by juveniles (96 h LC 50 = 10.87 mg/L, 95% CI = 9.38 to 12.36 mg/L) and adults (96 h LC 50 = 26.41 mg/L, 95% CI = 22.78 to 29.58 mg/L). During a 21-day chronic exposure, PAP at concentrations of 9-13 mg/L significantly inhibited adult growth and reproduction, with egg-laying nearly completely suppressed at concentrations ≥11 mg/L. Histopathological observations revealed hepatopancreatic acinar dilation, vacuolation, and necrosis, as well as gonadal follicle atrophy and germ cell degeneration, indicating direct damage to the metabolic and reproductive systems. This study integrates multiple lines of evidence linking “developmental sensitivity, functional impairment, and organ pathology,” suggesting that PAP may pose potential risks to mollusk populations under high or pulse exposure scenarios.
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DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2026
·
IF 6.7
Ming Xie,Yulin Tan,Zhenhua Zhi,Yanfang He,Dawei Cao
Titanium dioxide (TiO 2 ) has been extensively utilized owing to its outstanding physicochemical properties in the field of photocatalytic degradation. However, its efficiency is fundamentally limited by poor charge carrier mobility and severe recombination. These defects critically impair both charge utilization and reactive oxygen species generation. Herein, we in-situ hydrothermally grow ferroelectric barium titanate (BTO) layers on vertically aligned TiO 2 nanorod arrays (NRs), polarize the sample via an external electric field, and load graphene quantum dots (GQDs) through controlled impregnation, successfully constructing a TiO 2 /BTO-Polarized/GQDs (TiO 2 /BTO-P/GQDs) heterostructure. An external electric field induces a stable depolarization field in the BTO layer, creating a persistent interfacial driving force that enhances charge extraction from TiO 2 while suppressing bulk and surface electron-hole recombination. The BTO layer further acts as an electron transfer highway, efficiently channeling photogenerated electrons to GQDs. The π-conjugated system of GQDs serves as both an electron accumulation platform and a chemically active surface, facilitating pollutant adsorption and activation, thereby synergistically accelerating degradation kinetics through combined electron storage and catalytic effects. TiO 2 /BTO-P/GQDs demonstrated a 2.06-fold higher (OTC) degradation efficiency (82.5%) compared to unmodified TiO 2 (40%) within 90 min. This study provides novel insights into ferroelectric polarization-enhanced photocatalytic degradation efficiency. Implication This work presents a highly efficient, stable, and recoverable photocatalyst (TiO 2 /BTO-P/GQDs) for degrading persistent antibiotic pollutants like oxytetracycline in water. By enabling effective solar-driven remediation of agricultural wastewater, it offers a promising strategy to mitigate antibiotic contamination, protect aquatic ecosystems, and reduce risks to microbial communities and human health associated with residual antibiotics in the environment.
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DOI
高影响因子
Catalysts
·
2026
·Vol. 16
·期 5
·397
·
IF 4.5
Henan Shang,Qi Jia,Shilei Zhang,Sijia Li,Jinsheng Liang
A novel citric acid-assisted in situ reduction method has been developed for the synthesis of bimetallic AuPd alloy nanoparticles supported on amine–phosphate-functionalized carbon nanotubes (AuPd/NH2-P-CNTs). In this strategy, formic acid acts not only as the reducing agent for reducing metal precursors, but also as the hydrogen source for the subsequent catalytic dehydrogenation. The introduction of citric acid significantly accelerates the reduction kinetics and promotes the uniform formation of ultrafine AuPd nanoparticles (∼1.8 nm). As a result, the optimized Au0.5Pd0.5/NH2-P-CNTs exhibit an extraordinary catalytic activity and 100% H2selectivity during hydrogen generation from FA with sodium formate as an additive, affording a remarkable initial turnover frequency of 5663.94 mol H2mol Pd−1h−1at 303 K. The experimental results reveal that the -NH2and -P functional groups on the support are crucial for stabilizing and uniformly dispersing the alloy nanoparticles. Furthermore, the enhanced reaction rate can be attributed to the strong metal–support interaction established between AuPd nanoparticles and -NH2-P-CNT supports. This work provides a new perspective on the design of highly efficient Pd-based catalysts for hydrogen production from formic acid.
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DOI
高影响因子
JOURNAL OF VINYL & ADDITIVE TECHNOLOGY
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2026
·
IF 4
Zhihao Zhu,Bingtao Wang,Siqi Huo,Zhenghong Guo,Jinjun Tang,Juan Li
Developing flame-retardant epoxy resin (EP) with high performance has drawn extensive attention recently due to the growing public concern for fire safety. However, the simultaneous enhancement of flame retardancy and toughness without the sacrifice of mechanical strength and thermal stability is still a challenge for EP. Herein, a novel kind of imidazole-based reactive flame retardant MD containing P/N/Si was synthesized and applied into EP. The results demonstrated that due to the presence of P/N/Si multiple flame-retardant elements, incorporating 4 wt% MD could make EP/MD pass UL-94 V-0 grade and have a limiting oxygen index (LOI) of 29.7%. Meanwhile, compared with pure EP, the peak heat release rate (PHRR), total heat release rate (THR), peak smoke production rate (PSPR), and total smoke production (TSP) of EP composite containing 4 wt% MD exhibited an obvious reduction of 41.5%, 11.4%, 24.2%, and 12.9%, respectively. Moreover, thanks to the high reactivity of imidazole groups, the MD could participate in the cross-linking reactions of EP and form strong interfacial interaction between the matrix and flame retardant. Therefore, the mechanical strength and toughness as well as the glass transition temperature of EP/MD composites could be simultaneously and greatly enhanced (tensile strength +30%, flexural strength +35%, impact strength +22%, and T g + 7°C). This work provided a feasible methodology for the fabrication of highly efficient flame-retardant EP with prominent mechanical and thermal properties. Highlights A reactive flame-retardant MD containing DOPO groups, imidazole moieties, and siloxane segments was synthesized in mild conditions. MD endowed EP with satisfying flame-retardant and smoke suppression properties. EP/MD composites realized simultaneous improvement of fire safety, mechanical strength, and glass-transition temperature in a small amount of MD.
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DOI
高影响因子
POLYMER
·
2026
·
IF 5.1
Shuai Huang,Ziqiang Xiang,Yuhao Zhu,Renfeng Gong,Yicheng Wang,Ruoyi Liu,Guanjun Liu,Qingshan Wu
The rapid evolution of high-power flexible electronics necessitates materials that concurrently enable efficient heat dissipation and high-precision thermal monitoring. Conventional ionogels suffer from intrinsically low thermal conductivity, which induces severe thermal hysteresis, fundamentally compromising their accuracy in dynamic thermal detection. Herein, rather than treating copolymer regulation or h-BN filling as isolated design elements, we propose a thermally coupled ionogel design aimed at reconciling two usually conflicting requirements: rapid heat equilibration and high thermoresistive sensitivity. P(DMAA-co-AAM)/h-BN composite ionogels are fabricated via in-situ UV-initiated free-radical polymerization, in which N,N-dimethylacrylamide (DMAA) and acrylamide (AAM) form a mechanically compliant and ion-transportable copolymer network, lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) provides thermally activated ionic pathways, and hexagonal boron nitride (h-BN) nanosheets introduce filler-assisted thermal transport pathways. Systematic optimization reveals that a DMAA-to-AAM mass ratio of 3:1 with 20 wt% h-BN yields the optimal synergy among mechanical flexibility, thermal transport, and ionic conduction. The resulting composite achieves a thermal conductivity of 0.469 W/(m·K), representing a ∼160% enhancement over the pristine matrix, which effectively suppresses heat accumulation. Concurrently, the ionogel exhibits an ultra-high temperature coefficient of resistance (TCR) of −13.5%/°C and a thermosensitive coefficient (B value) of 3879 K within 0-20°C. Benefiting from the enhanced thermal transport performance, the dynamic thermal response speed of this series of ionogel sensors (30°C → 35°C) is significantly accelerated with the increase of h-BN loading: the T90 response time of the 10 wt%, 20 wt%, and 30 wt% h-BN samples is 32.40 s, 24.34 s, and 15.14 s respectively. Meanwhile, the devices can still maintain stable and reversible resistance switching characteristics over 50 heating-cooling cycles. This study achieves the synergistic enhancement of the thermal management and temperature sensing performance of the ionogel, providing an ideal material platform for the next-generation wearable electronic devices and intelligent thermal management systems.
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Yinfei Wang,Mengjiao Li,Yuhong Su,Ying Sun,Chenqi Peng,Han Cheng,Bowen Wang,Hongxia Zhao
To address the challenges of low hydrogen peroxide(H 2 O 2 ) utilization efficiency in traditional homogeneous systems, this study successfully developed a novel photocatalytic colloidal clay mineral composite gel microsphere system (Fe 0 -OA-P/Gel-H 2 O 2 ). This system achieved efficient degradation of p-nitrophenol (PNP, 50 mg/L) in aqueous solutions through the synergistic activation of O 2 and H 2 O 2 to generate hydroxyl radicals (·OH), demonstrated a remarkable H 2 O 2 utilization rate of 91.55 %. The system exhibited 89.45 % PNP degradation efficiency with 64.87 % total organic carbon (TOC) removal. Under optimized conditions, the pseudo-first-order kinetic model revealed a degradation rate constant of 0.0084 min −1 , representing a 28.84-fold enhancement compared with H 2 O 2 systems. Radical quenching experiments combined with in situ EPR analysis confirmed a multi-path synergistic degradation mechanism to PNP, involving ·OH, superoxide radicals (·O 2 − ), and singlet oxygen ( 1 O 2 ). Material characterization through EDS and XRD spectra identified Fe-O-Si active sites on the microsphere surfaces. FTIR and XPS analyses verified successful encapsulation of Fe 0 within the gel matrix and its subsequent oxidation to Fe 2+ /Fe 3+ during photocatalytic processes. TG analysis demonstrated excellent thermal stability (weight loss <15 % below 150 °C), superior water absorption capacity (8.0 g/g) and adsorption capability for strongly polar organic pollutants. The introduction of oxalic acid as an electron shuttle significantly enhanced photoelectron transfer efficiency, increasing ·OH generation by 2–3 folds and achieving a quantum efficiency of 27.07 %. This study innovatively develops an efficient heterogeneous photocatalytic activation system through colloidal-clay mineral composite gel microspheres, which demonstrating significant potential for treating refractory organic pollutants in water and soil environments.
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Lei Sun,Meng Yang,Hao Guo,Tingting Zhang,Ning Wu,Mingyue Wang,Fan Yang,Junye Zhang,Wu Yang
Herein, covalent organic framework (COF) and covalent triazine framework (CTF) have been successfully combined for electrochemical sensing via carboxylated multi-walled carbon nanotubes (COOH-MWCNTs). The COF was synthesized from 1,3,5-tris-(4-formylphenyl) benzene (TFPB) and benzidine (BD), named TFPB-BD-COF. Meanwhile, CTF was synthesized by 1, 4-dicyanobenzene (DCB), then chemically activated with KOH at 700 °C to obtained chemically activated porous product, caCTF-1–700. A novel electrochemical sensor based on TFPB-BD-COF/caCTF-1–700/COOH-MWCNT composite was constructed for simultaneous detection of acetaminophen (ACOP) and 4-aminophenol (4-AP). The electrochemical behaviors of the ACOP and 4-AP on the TFPB-BD-COF/caCTF-1–700/COOH-MWCNT electrode were explored via differential pulse voltammetry (DPV) and cyclic voltammetry (CV). The fabricated TFPB-BD-COF/caCTF-1–700/COOH-MWCNT composite modified glassy carbon electrode (GCE) possessed outstanding electrocatalytic performance for the electro-oxidation of acetaminophen (ACOP) and 4- aminophenol (4-AP). Under optimal conditions, the linear ranges were 0.6–150 μM for ACOP and 4-AP, respectively, with the low detection limits of 0.053 μM and 0.075 μM, respectively. In addition, it also showed excellent selectivity, repeatability, reproducibility and stability. The proposed modified electrode was applied for the determination of ACOP and 4-AP in acetaminophen tablet and Yellow river water and obtained satisfactory recovery between 96.31~103.96% and 97.2~101.6%, respectively.
研究领域:
分析化学
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电化学
·
生物传感器
·
药物分析
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环境监测
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材料科学
·
纳米技术
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DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2026
·
IF 6.8
Xiuyan Guo,Yufei Cao,Ling Sun,Yuhan Wang,Xiaohui Liu,Yuanlin Ren,Yuesheng Li
Developing high-performance epoxy resins (EP) that integrate outstanding flame retardancy, mechanical reinforcement and optical transparency is a persistent challenge, often hindered by the detrimental effects of conventional additives. Herein, a novel hyperbranched polymeric flame retardant (HPBAE) containing phosphorus and borate ester moieties was synthesized from boric acid, ethanolamine and phenylphosphonic dichloride. Remarkably, incorporation of merely 2 wt% HPBAE substantially boosted the flammability resistance of resin to the UL-94 V-0 rating with 32.9% limiting oxygen index (LOI) and a 23.4% suppression in the peak heat release rate (PHRR). The superior flame retardancy arises from dual-phase action: condensed-phase formation of a P/B-rich thermal barrier char and gas-phase release of phosphorus radicals that quench H · /HO · combustion intermediates. Relative to pure EP, the EP/HPBAE-2 exhibited a 57.9% enhancement in tensile strength while retaining the optical transparency. The synergistic effects imparted by HPBAE not only provide a balanced property profile but also offer a viable design paradigm for developing high-performance, transparent and flame-retardant epoxy composites.
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DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Qian Liu,Liulin Wei,Xiaomei Chen,Xueyun Gao,Jingchan Zhao
In this work, we rationally designed a facile dispersible and self-collectible nano-adsorbent GR@p(POSS-co-DMAEMA) to simplify the dispersive solid-phase microextraction (DSPME). The difficulty of allowing close contact between the nano-adsorbent and donor sample solution was solved, thus improving the extraction efficiency. Furthermore, the GR@p(POSS-co-DMAEMA) with temperature-sensitive property can self-collect at high temperature, simplifying the DSPME steps (7 min). Fabrication and dispersity of GR@p(POSS-co-DMAEMA) were certified by characteristic analyses. Based on above, a method for analyzing four parabens by GR@p(POSS-co-DMAEMA)-DSPME combined with HPLC-UV was established. The feasibility of the method was verified in simulated water targeting four parabens with good precision (RSD%, 1.7–11.3, n = 3) and low detection limits (0.29–0.63 ng mL −1 ) under optimal conditions. The method was successfully applied to analyze three condiments and obtained relative recoveries between 91.20 and 133.71%. The results showed that the proposed method is promising to be a fast, efficient and reliable method for the trace analysis of parabens.
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产品关联
DOI
高影响因子
POLYMER DEGRADATION AND STABILITY
·
2023
·
IF 5.9
Yadong Wang,Li Ma,Jun Yuan,Zongmin Zhu,Xiaoming Liu,Dengsong Li,Liqing He,Fei Xiao
The development of high-performance EP composites with high glass transition temperature (T g ), excellent flame retardancy, and UV resistance is a challenging topic in the flame retardancy community. In this work, a bio-based phosphorus/nitrogen/sulfur (P/N/S) containing flame retardant (FDI) was prepared from furfural, 2-amino-5-nitrothiazole, and DOPO. It was applied to improve the flame retardant, dielectric, and UV-resistant properties of EP. Thanks to the combination of phosphorus, nitrogen, and sulfur in FDI, the EP/FDI composites showed superior flame retardancy. Only adding 5 wt% FDI made EP achieve UL-94 V-0 flammability rating with a limiting oxygen index (LOI) of 27%. Meanwhile, EP/FDI-5% composite showed significant reduction of 65.1% and 33.6% in total smoke production (TSP) and the peak heat release rate (pHRR), respectively. The flame-retardant mechanisms of EP/FDI thermosets were investigated by residual char photographs, SEM, XPS, and Py/GC-MS. Moreover, compared to pure EP, EP/FDI composites showed excellent UV resistance, low dielectric properties, and high glass transition temperature, which was expected to be extensively used in multiple areas of production.
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产品关联
DOI
高影响因子
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