Advanced Composites and Hybrid Materials
·
2025
·Vol. 8
·期 6
·442
·
IF 21.8
Zhang Xueyan,Zhou Jien,Lv Shiyu,Yuan Tian,Yang Pu,Yao Yanpo,Liang Junfeng,Luo Yanli,Gao Tongguo,Wang Feng
The accumulation of phenolic acid autotoxins is a key factor contributing to the challenges of continuous chili cropping, but efficient and stable remediation methods are currently lacking. This study innovatively employs K₂CO₃ alkali etching to prepare engineered biochar as a laccase carrier, achieving high-efficiency immobilization via glutaraldehyde cross-linking (maximum loading capacity: 177.3 U/g). Compared to free laccase, the immobilized system exhibits significant advantages: broader pH and temperature adaptability, enhanced long-term storage stability, and improved reusability. Experimental results demonstrate that 2 U/mL of immobilized laccase can completely degrade 20 mg/L phthalic acid within 10 h and is effective against multiple chili autotoxic phenolic acids (ferulic acid, cinnamic acid, coumaric acid, and p-hydroxybenzoic acid). After phthalic acid degradation, the solution no longer inhibits chili seed germination, and soil experiments confirm a degradation rate of 51.07% after 11 days. Mechanistic studies reveal that the degradation process relies on synergistic radical and non-radical pathways, with electron transfer playing a dominant role. LC–MS analysis confirms the transformation of phenolic acids into low-toxicity small molecules. This study is the first to propose a biochar-immobilized laccase synergistic degradation strategy, which offers high efficiency, environmental safety, sustainability, and broad applicability compared to existing methods.
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Advanced Fiber Materials
·
2025
·
IF 21.3
Zhu Mengjia,Li Shuo,Bi Peng,Liang Huarun,Wu Xun-En,Zhang Chi,Song Xian,Yu Aifang,Xu Jingtao,Lu Haojie,Wang Haomin,Zhai Junyi,Li Yi,Zheng Zijian,Zhang Yingying
Augmented-tactility wearable devices have attracted significant attention for their potential to expand the boundaries of human tactile capabilities and their broad applications in medical rehabilitation. Nonetheless, these devices face challenges in practical applications, including high susceptibility to the operating environments, such as variations in pressure, humidity, and touch speed, as well as concerns regarding wearability and comfort. In this work, we developed an augmented-tactility superskin, termed AtSkin, which integrates a skin-compatible nanofiber sensor array and deep learning algorithms to enhance material recognition regardless of the ambient environment. We fabricated a lightweight and breathable triboelectric sensor array with multilayer nanofiber architectures through electrospinning and hot pressing. The carefully selected combination of sensing layers can capture the electrical characteristics of different materials, thus enabling their distinction. Combined with deep learning algorithms, AtSkin achieved an accuracy of 97.9% in distinguishing visually similar resin and fabric materials, even under varying environmental pressures and humidities. As a proof of concept, we constructed an intelligent augmented-tactility system capable of identifying fabrics with similar textures and hand feel, demonstrating the potential of the superskin to expand human tactile capabilities, enhance augmented reality experiences, and revolutionize intelligent healthcare solutions. Graphical
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 10
·1-10
·
IF 5.3
Su Shicheng,Hu Jing,Zhu Yichun,Liang Bing,Zhu Yaping,Zhang Shuifeng,Sheng Huadong,Chen Hongbo,Xianyu Yunlei,He Chunyan
An all-in-one assay based on the electrical conductivity (EC) has been developed that enables the viability test and the specific detection of pathogenic bacteria, including the differentiation of (1) live/dead bacteria, (2) drug-sensitive/resistant bacteria, (3) Gram-positive/negative bacteria, and (4) specific detection of A. baumannii . Key to this assay is the modification of gold nanoparticles on the surface of bacteria that can amplify the EC signal for enhanced sensitivity and rapid detection. The amplification effect of gold nanoparticles significantly reduces the time and enhances the sensitivity for bacteria detection. This EC-based assay outcompetes traditional colorimetric and fluorescent methods owing to its rapid response, convenient operation, and low cost, which holds great promise for biosensing. Graphical abstract
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JOURNAL OF FLUORESCENCE
·
2025
·
IF 3.1
Gao Lu,Zhao Haimei,Zhou Xiaodan,Zhao Yuxian,Wang Yidi,Geng Huaixiao,Xu Jia,Zhang Zhichao,Han Shuang
Copper and nitrogen co-doped fluorescent carbon quantum dots (Cu-NCDs) were synthesized via a one-pot hydrothermal synthesis method using L-tyrosine and copper chloride as precursors. The as-prepared Cu-NCDs exhibited bright blue fluorescence (emission peak at 427 nm) with high photostability (10.5% intensity loss after 1 h irradiation at 365 nm). Upon introduction of tetracyclines antibiotics (TCs), include oxytetracycline (OTC), chlortetracycline (CTC) and tetracycline (TC), the fluorescence intensity of Cu-NCDs was selectively quenched through fluorescence resonance energy transfer (FRET), as confirmed by time-resolved fluorescence decay analysis. This phenomenon established a linear relationship between fluorescence quenching efficiency and TCs concentration. The calculated limits of detection (S/ N = 3) for three target analytes were determined to be 0.24 µM (OTC), 0.56 µM (CTC), and 0.19 µM (TC), respectively. Accurate quantification of TCs residues in tap water and dairy products demonstrated recovery rates of 97.94 − 112.20% (OTC), 94.93 − 110.00% (CTC), and 97.58 − 107.67% (TC), with relative standard deviations (RSDs) below 4.16% ( n = 3). Based on the paper sensor platform, on-site detection of TCs has been achieved, and visual semi quantitative analysis can be completed within 1 min.
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FOOD SCIENCE AND BIOTECHNOLOGY
·
2025
·
IF 3.1
Nho Soo Bin,Do Sang-Hun,Oh Seongjin,Park Yong-Cheol,Kim Sun-Ki
This study aimed to develop a non-genetically modified organism (non-GMO) Saccharomyces cerevisiae strain with enhanced glutathione production using UV-induced random mutagenesis. Among 30 wild-type strains, S. cerevisiae KACC 48331 was selected for its high glutathione production. A #14 mutant with significantly higher glutathione content was isolated via acrolein resistance screening. Optimal batch fermentation was established at 20 °C and pH 4.5 using a cost-effective medium of molasses and corn steep liquor (CSL). In fed-batch fermentation, the #14 mutant achieved 1.98 g/L of glutathione using molasses and CSL as carbon and nitrogen sources, comparable to yields from expensive complex media containing peptone and yeast extract. Notably, over 99% of the glutathione produced was in the reduced, biologically active form. These results demonstrate the feasibility of using non-GMO yeast and industrial by-products for sustainable and economical glutathione production.
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ONCOGENE
·
2025
·
IF 7.3
Ren Yuqing,Ming Ruijie,Zuo Anning,Liu Shutong,Ba Yuhao,Zhang Yuyuan,Chen Yukang,Pan Teng,Luo Peng,Cheng Quan,Deng Jinhai,Yue Yi,Xu Hui,Weng Siyuan,Han Xinwei,Zhou Dongdong,Liu Zaoqu
The role of cancer-associated fibroblasts (CAFs) in the initiation and invasion phases of human lung adenocarcinoma (LUAD) development is not fully understood. In this study, we utilized single-cell RNA sequencing, spatial transcriptomics, and a combination of in vivo and in vitro models to decode the dynamics of tumor-stroma interactions during human LUAD progression, focusing primarily on adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IAC). We identified a matrix CAF (mCAF) subtype characterized by high THBS2 expression, which was closely associated with poor clinical outcomes, tumor recurrence, and the invasive dynamics of LUAD. Spatial transcriptomics and multiplex immunohistochemistry analysis revealed that this CAF subpopulation was closely associated with tumor cells, with clear spatial colocalization. In vivo and in vitro experiments demonstrated that THBS2 secreted by these mCAFs directly binds to SDC4 on tumor cells, enhancing tumor epithelial-mesenchymal transition (EMT) programs. This study highlights THBS2+ mCAFs as key regulators of tumor-stroma interactions and identifies the THBS2-SDC4-EMT axis as a potential therapeutic target in LUAD.
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Nano-Micro Letters
·
2023
·Vol. 16
·期 1
·1-17
·
IF 26.6
Nan Jingya,Sun Yue,Yang Fusheng,Zhang Yijing,Li Yuxi,Wang Zihao,Wang Chuchu,Wang Dingkun,Chu Fuxiang,Wang Chunpeng,Zhu Tianyu,Jiang Jianchun
Solid-state zinc-ion capacitors are emerging as promising candidates for large-scale energy storage owing to improved safety, mechanical and thermal stability and easy-to-direct stacking. Hydrogel electrolytes are appealing solid-state electrolytes because of eco-friendliness, high conductivity and intrinsic flexibility. However, the electrolyte/electrode interfacial contact and anti-freezing properties of current hydrogel electrolytes are still challenging for practical applications of zinc-ion capacitors. Here, we report a class of hydrogel electrolytes that couple high interfacial adhesion and anti-freezing performance. The synergy of tough hydrogel matrix and chemical anchorage enables a well-adhered interface between hydrogel electrolyte and electrode. Meanwhile, the cooperative solvation of ZnCl 2 and LiCl hybrid salts renders the hydrogel electrolyte high ionic conductivity and mechanical elasticity simultaneously at low temperatures. More significantly, the Zn||carbon nanotubes hybrid capacitor based on this hydrogel electrolyte exhibits low-temperature capacitive performance, delivering high-energy density of 39 Wh kg −1 at −60 °C with capacity retention of 98.7% over 10,000 cycles. With the benefits of the well-adhered electrolyte/electrode interface and the anti-freezing hydrogel electrolyte, the Zn/Li hybrid capacitor is able to accommodate dynamic deformations and function well under 1000 tension cycles even at −60 °C. This work provides a powerful strategy for enabling stable operation of low-temperature zinc-ion capacitors.
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Nano-Micro Letters
·
2023
·Vol. 15
·期 1
·1-18
·
IF 26.6
Wen Jing,Wu Yongchuan,Gao Yuxin,Su Qin,Liu Yuntao,Wu Haidi,Zhang Hechuan,Liu Zhanqi,Yao Hang,Huang Xuewu,Tang Longcheng,Shi Yongqian,Song Pingan,Xue Huaiguo,Gao Jiefeng
A nanofiber composite reinforced organohydrogel with multifunctionality is prepared.
The composite organohydrogel possesses multiple interfacial bondings and multi-level strengthening and toughening mechanism is proposed.
The composite organohydrogel exhibits long-term strain sensing stability and can be used for high performance electromagnetic interference shielding.
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BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
·
2025
·Vol. 115
·期 3
·1-7
·
IF 2.2
Wang Yun,Shan Ning,Habibul Zumrat,Habibul Nuzahat
This study investigated the impact of pH on the combined toxicity of polystyrene microplastics (MPs) and ciprofloxacin (CIP) on ryegrass growth and CIP uptake. Two different sizes of PS-COOH (200 and 500 nm) were utilized. The findings indicated that neutral and alkaline pH conditions (pH 7.0 and 8.8) significantly reduced CIP accumulation in ryegrass roots, regardless of MP presence. Conversely, CIP content in shoots (including leaves) increased with rising pH, showing 24.7-fold and 29.5-fold enhancements under CIP + 200 nm MPs and CIP + 500 nm MPs treatments at pH 8.8 compared to pH 5.3. Additionally, pH significantly influenced growth inhibition, with more pronounced effects at pH 7.0 and 8.8 than at pH 5.3. Under neutral and alkaline conditions, shoot lengths in 500 nm MPs + CIP and 200 nm MPs + CIP treatments were reduced to 50.3%, 69.7% and 86.8%, 81.3% of those at pH 5.3, respectively. These findings highlight the critical role of pH in modulating CIP uptake and toxicity in ryegrass, particularly in MP co-contaminated environments. Moreover, the relatively high CIP removal efficiency suggests the potential of ryegrass for CIP remediation in MP-polluted systems.
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NATURE
·
2025
·Vol. 637
·期 8047
·846-853
·
IF 48.5
Song Huimin,Münch Konrad,Liu Xu,Shen Kaier,Zhang Ruizhuo,Weintraut Timo,Yusim Yuriy,Jiang Dequan,Hong Xufeng,Meng Jiashen,Liu Yatao,He Mengxue,Li Yitao,Henkel Philip,Brezesinski Torsten,Janek Jürgen,Pang Quanquan
With promises for high specific energy, high safety and low cost, the all-solid-state lithium–sulfur battery (ASSLSB) is ideal for next-generation energy storage 1 , 2 , 3 , 4 , 5 . However, the poor rate performance and short cycle life caused by the sluggish solid–solid sulfur redox reaction (SSSRR) at the three-phase boundaries remain to be solved. Here we demonstrate a fast SSSRR enabled by lithium thioborophosphate iodide (LBPSI) glass-phase solid electrolytes (GSEs). On the basis of the reversible redox between I − and I 2 /I 3 − , the solid electrolyte (SE)—as well as serving as a superionic conductor—functions as a surficial redox mediator that facilitates the sluggish reactions at the solid–solid two-phase boundaries, thereby substantially increasing the density of active sites. Through this mechanism, the ASSLSB exhibits ultrafast charging capability, showing a high specific capacity of 1,497 mAh g −1 sulfur on charging at 2C (30 °C), while still maintaining 784 mAh g −1 sulfur at 20C. Notably, a specific capacity of 432 mAh g −1 sulfur is achieved on charging at an extreme rate of 150C at 60 °C. Furthermore, the cell demonstrates superior cycling stability over 25,000 cycles with 80.2% capacity retention at 5C (25 °C). We expect that our work on redox-mediated SSSRR will pave the way for developing advanced ASSLSBs that are high energy and safe.
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NATURE
·
2025
·
IF 48.5
Lin Yuexin,Lin Zhichao,Lv Shili,Shui Yuan,Zhu Wenjing,Zhang Zuhong,Yang Wenhan,Zhao Jinbo,Gu Hao,Xia Junmin,Wang Danning,Du Fenqi,Zhu Annan,Liu Jin,Cai Hairui,Wang Bin,Zhang Nan,Wang Haibin,Liu Xiaolong,Liu Tao,Kong Chuncai,Zhou Di,Chen Shi,Yang Zhimao,Li Tao,Ma Wei,Fang Guojia,Echegoyen Luis,Xing Guichuan,Yang Shengchun,Yang Tao,Cai Wenting,Li Meng,Huang Wei,Liang Chao
A critical challenge in the commercialization of perovskite solar cells (PSCs) is the simultaneous attainment of high power conversion efficiency (PCE) and high stability. Employing polymers interfaces in PSCs can enhance durability by blocking water and oxygen, and by suppressing ions interdiffusion, but their electronic shielding poses a challenge for efficient and stable PSCs 1–3 . In this study, we report a magnetic endohedral metallofullerene Nd@C 82 -polymer coupling layer, which features ultra-fast electron extraction and in-situ encapsulation, thereby promoting homogeneous electron extraction and suppressing ions interdiffusion. The Nd@C 82 -polymer coupling layer in PSCs exhibited PCE of 26.78% (certified 26.29%) and 23.08% with an aperture area of 0.08 square centimetres and 16 square centimetres (modules), respectively. The unencapsulated devices retained ~82% of the initial PCE after 2,500 hours of continuous 1-sun maximum power point operation at 65 °C.
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NATURE
·
2025
·
IF 48.5
Zhu Bao,Zhang Yanjun,Gao Rong,Wu Zhihua,Zhang Wei,Zhang Chao,Zhang Penghong,Ye Can,Yao Linbo,Jin Ying,Mao Hui,Tou Peiyao,Huang Peng,Zhao Jiangzhe,Zhao Qiao,Liu Chang-Jun,Zhang Kewei
Salicylic acid (SA) is a pivotal phytohormone for plant responses to biotic and abiotic stresses. Plants have evolved two pathways to produce SA: the isochorismate synthase and phenylalanine ammonia lyase (PAL) pathways 1 . Whereas the isochorismate synthase pathway has been fully identified 2 , 3 , 4 , the PAL pathway remains incomplete. Here we report the full characterization of the PAL pathway for SA biosynthesis via functional analysis of rice ( Oryza sativa ) SA-DEFICIENT GENE 1 ( OSD1 ) to OSD4 . The cinnamoyl-coenzyme A (CoA) ligase OSD1 catalyses the conversion of trans -cinnamic acid to cinnamoyl-CoA, which is subsequently transformed to benzoyl-CoA via the β-oxidative pathway in peroxisomes. The resulting benzoyl-CoA is further converted to benzyl benzoate by the peroxisomal benzoyltransferase OSD2. Benzyl benzoate is subsequently hydroxylated to benzyl salicylate by the endoplasmic reticulum membrane-resident cytochrome P450 OSD3, which is ultimately hydrolysed to salicylic acid by the cytoplasmic carboxylesterase OSD4. Evolutionary analyses reveal that the PAL pathway was first assembled before the divergence of gymnosperms and has been conserved in most seed plants. Activation of the PAL pathway in rice significantly enhances salicylic acid levels and plant immunity. Completion of the PAL pathway provides critical insights into the primary salicylic acid biosynthetic pathway across plant species and offers a precise target for modulating crop immunity.
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危险品化学品经营许可证（带存储）