Catalysts
·
2024
·Vol. 14
·期 12
·858
·
IF 3.8
Feng Feng,Yajing Liu,Li Yao,Xiuyu Wang
Creatine catalase (CAT), superoxide dismutase (SOD), and NADPH oxidase (NOX) are natural enzyme molecules that play a crucial role in regulating reactive oxygen species (ROS) in biological systems. They maintain life activities and eliminate pathogens by catalyzing various biochemical reactions. However, natural enzymes have some drawbacks in ROS control; they may lose activity under certain environmental conditions, such as high temperatures, extreme pH values, or the presence of organic solvents, which affects their stability and reliability in different applications. The construction of artificial nanozymes is an emerging technology that could probably solve the problems existing in natural enzymes. This study introduces a type of dendritic platinum–iron oxide (DPIO) nanozyme. The unique dendritic structure of this DPIO nanozyme provides a high surface area-to-volume ratio, and the addition of a platinum layer on the surface offers stability, thereby effectively enhancing the catalytic efficiency of producing reactive oxygen species (ROS). The combination of iron-based Fenton reactions and platinum-based Fenton-like reactions in this DPIO nanozyme drastically improves ROS catalytic efficiency. This artificial nanozyme has a high level of biosafety and displays no cytotoxicity. The development of DPIO nanozymes marks a significant advancement in the technology of artificial nanozymes.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Haoyang Xu,Yage Zheng,Yue Shen,Chaoqun Mu,Zhiqiang Zhang,Zhixian He,Yao Wang,Juanqin Xue,Liang Zhang
In this work, the photocatalyst BiOCOOH/BiYO 3 /Chitosan (CS) was prepared by using CS as the carrier and adsorbent. The performance of the material was studied through the photocatalytic degradation of tetracycline (TC) in water. Theoretical calculations and experiments demonstrate that the formation of BiOCOOH/BiYO 3 heterojunctions improves the separation of photogenerated carriers and the absorption of visible light by the material. The introduction of CS improves the difficulties in material recovery, demonstrating exceptional degradation ability for TC under the action of adsorption and photocatalysis. Adsorption kinetics studies indicate that the adsorption of TC by BiOCOOH/BiYO 3 /CS fits the pseudo-second-order model better, while the adsorption at different concentrations of TC is more suitably described by the Freundlich isotherm model. The synthesis of BiOCOOH/BiYO 3 /CS was confirmed by the analysis of XRD, XPS, and FTIR. UV–vis DRS showed that the synthesis of BiOCOOH/BiYO 3 /CS broadened the range of light absorbed by the material. The testing results of PL and transient photocurrent density indicate that BiOCOOH/BiYO 3 exhibits a higher efficiency in separating photogenerated charge carriers. After 5 cycles of reuse, the degradation efficiency can still reach 90 % of the initial efficiency, indicating that CS-based photocatalytic composite catalysts have practical application potential in the field of water pollution treatment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Bo Xu,Guoxiang Pan,Xinyu Fan,Haijie Zhou,Chengcong Qiu,Yuhua Guo,Minhong Xu,Jingwei Sun,Xinhui Xia
Conventional jungle-camouflage materials exhibit four prominent vibration peaks (green peak, red-edge, plateau, and water absorption peaks) on the green-vegetation spectrum. However, they cannot accurately simulate the water peaks of green vegetation, and this limits their application efficiency and considerably hinders their further development. Here, an environment-friendly camouflage coating comprising MgAlFe-LDHs-CA, ZnAl-LDH-AG, and BiVO 4 is proposed to facilitate the precise simulation of NIR spectrum of green-vegetation. Next, the developed material is characterized by XRD, FT-IR, TG-DTA, SEM and XPS techniques. The characterization results reveal that the newly developed jungle-camouflage-coating material achieves a 97.56 % simulation of green vegetation. Additionally, the similarity analysis results of the prepared camouflage coating confirm that it simulated all the spectral characteristics of green vegetation. Thus, we propose a new environment-friendly hydrotalcites camouflage material, thereby offering a new research direction in the development of camouflage materials.
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Yu Lan,Haixia Zhang,Ruichen Xie,Kecheng Li,Feiran Xie,Peihong Xiao,Li Jiang
Glaucoma is a leading cause of irreversible blindness worldwide and characterized by progressive loss of retinal ganglion cells (RGCs). As glaucoma progresses asymptomatically and the lack of specific biomarkers or noninvasive imaging tools during the early stage, it is often discovered at a relatively late stage without cure. Development of an effective tool for early diagnosis remains a necessity. As well known, endoplasmic reticulum (ER) stress and subsequent accumulation of reactive oxygen species (ROS) play a vital role in the development of glaucoma, with peroxynitrite (ONOO − ) as one of the most abundant cytotoxic ROS. In this work, we constructed a novel near-infrared (NIR) fluorescent nanoprobe named ER-ONOO-NPs. It specifically and sensitively targets ER-associated ONOO − with low biotoxicity in cultured RGCs. Systematically applied to the NMDA-induced mouse model of glaucoma, ER-ONOO-NPs performs well for real-time dynamic monitoring of ONOO − fluctuations at the Ganglion cell layer of mice prior to RGCs apoptosis. Thus, our results suggest that the ER-targeted NIR fluorescent nanoprobe could be a noninvasive imaging tool for early diagnosis of glaucoma in high-risk population.
✓ 已验证
产品关联
DOI
高影响因子
Applied Materials Today
·
2024
·
IF 7.2
Xi Wang,Yu Wang,Qihang Zhao,Zhenchu Feng,Qingyi Liu,Gang Wang,Jiakui Zheng,Lin Tao,Jianguo Zhang,Xi Chen
Photothermal immunotherapy, especially combined with immune checkpoint inhibitors (ICIs) targeting programmed cell death 1 (PD-1), marks a breakthrough in cancer treatment. However, therapy often triggers compensatory upregulation of other immune checkpoints. This study introduces an advanced strategy to enhance the efficacy of photothermal immunotherapy by utilizing a novel nanocarrier that targets both PD-1 and T-cell immunoreceptor with Ig and ITIM domains (TIGIT) immune checkpoints. The dual blockade could counteract the compensatory upregulation of immune checkpoints triggered by PD-1 targeted therapies alone. The nanocarrier of this work is composed of a ZrB 2 photothermal core and a mesoporous silica layer, and finally coated with biocompatible polydopamine. This design could effectively deliver both TIGIT and PD-1 inhibitors directly to tumor sites, minimizing systemic side effects such as cytokine release syndrome. We demonstrate that this approach not only enhances cytotoxic responses of T and NK cells, but also promotes macrophage polarization towards a tumor-suppressing M1 phenotype dendritic cell maturation and immunogenic cell death. Our findings provide a promising avenue for cancer immunotherapy.
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2024
·
IF 7.1
Anamika Kushwaha,Lalit Goswami,Beom Soo Kim
In this study, we established an innovative and integrated chemical/biological methodology for the complete poly(ethylene terephthalate) (PET) degradation and biopolyol production using cerium–iron oxide nanoparticles (CeFeNPs). Initially, three nanoparticles, i.e., CeNPs, FeNPs, and CeFeNPs, were synthesized and evaluated for PET glycolysis. CeFeNPs demonstrated the best catalytic performance for PET depolymerization to bis(2-hydroxyethyl) terephthalate (BHET) and were further recovered from the PET depolymerized slurry to be reutilized again. BHET was further biodegraded using the hydrocarbonoclastic bacterium Pseudomonas aeruginosa PR3 under the batch modes using a shake flask and a stirred tank bioreactor. To elucidate the fate of BHET biodegradation under aerobic conditions, identification of various BHET degraded metabolites was carried out using liquid chromatography–mass spectrometry analysis. The strain could produce an extracellular diol synthase enzyme, which transforms oleic acid into the biopolyol, 7,10-dihydroxy-8(E)-octadecenoic acid (DOD). CeFeNPs were further supplemented to enhance DOD production via whole cell and cell-free approaches.
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Yang Zhen,Jingyuan Chen,mengyu Liu,Jiabao Huang,Jieping Liang,Mengjiao Zhu,Yuanwei Shen,Danqing Li,Chong Lei,Xuecheng Sun
An integrated magnetoimpedance (MI) biosensor microfluidic magnetic platform was proposed for the evaluation of of cardiac markers cardiac troponin-I (cTnI). The bioanalytes evaluation platform mainly contained external permanent magnets (PMs), MI elements, peelable SiO2film units and microfluidic chip (MFC). The MI elements were made of micro-electro-mechanical system (MEMS)-based multilayered [Ti(6 nm)/FeNi(100 nm)]5/Cu(400 nm)/[Ti(6 nm)/FeNi(100 nm)]5 thin films and designed as meander structures with closed magnetic flux. The MFC was fabricated by using 3D printing and inverted molding techniques, and designed with a solution mixing reaction region, a magnetic separation region and detection regions. Peelable SiO2 film units with the same size as the MI sensing element are used for bioanalytes immunoreactivity interface. Two large PMs were placed directly below the MI sensing unit to provide a bias magnetic field, and the smaller PM was embedded in MCF for magnetic separation function. The different concentration biological target (cTnI antigen), PBS buffer and Dynabeads labeled polyclonal cTnI antibody solution are injected sequentially into the MCF. After immunoreactivity and magnetic separation, a classical sandwich immunoreaction process occured on the surface of the monoclonal antibody-modified SiO2 film via self-assembling technology in the reaction region of MFC. The fundamental principle for evaluation of cTnI was based on variation of the MI signal under different concentration biological target coupled with different number of Dynabeads. It was demonstrated that the mentioned MI-based magnetic platform can perform detection analyses over a range of cTnI concentrations (lowest concentration 0.1 ng/ml and highest concentration 100 ng/ml). The proposed MI-based magnetic platform provides a sensitive, reliable, stable and reusable bioanalytical platform and has potential for future biomedical applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Xuan Wu,Xingwu Guo,Chenjing Gao,Jing Luo,Lewen Nie,Juan Chen,Liming Peng
WO 3 -based optical hydrogen sensors, while advantageous due to their ignition-free operation and resistance to electromagnetic interference, face limitations due to slow response kinetics in hydrogen gasochromic processes. This study presents a novel post-treatment method using aqueous sulfuric acid, which significantly enhances the response speed of mesoporous Pt/WO 3 films. After treatment, the films exhibit an ultrashort response time of 2.4 s towards 4% H 2 /Ar, a marked improvement from 7.1 s prior to the treatment. The treated films also show excellent reversibility of 120 gasochromic cycles. The adsorbed acid layer is proved to be the cause of accelerated hydrogen gasochromic response. This exceptional performance is attributed to increased proton conductivity and the high porosity of the mesoporous structure. A modified model is proposed for the acceleration effect by acid post-treatment. Our post-treatment method represents a significant advancement in the reliable detection of hydrogen leaks at room temperature.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Minglong He,Junjie Shi,Anyu Zhang,Yuying Xu,Qing Wu,Li Wen,Qi Hong,Yang Yue,Siliang Wang
The plentiful and renewable nature of iodine confers metal-iodine batteries (MIBs) a benefit in the advancement of energy storage technology with high energy and power densities. However, dendrite growth and susceptibility to electrolyte corrosion not only result in low anode utilization but also severely affect battery stability. This paper introduces an ammonium-iodine batteries (AIBs) structure that leverages the inertness of organic materials to iodide ions, thereby avoiding the electrolyte corrosion issues commonly found in the metal anodes of traditional MIBs. Additionally, the use of a non-metallic anode eliminates the impact of dendrite growth on battery stability and increases the anode utilization rate. Because of these features, AIBs attain a high specific capacity of 242mAh g −1 and preserve an 80.7 % capacity retention rate following approximately 2000 cycles at a current density of 10 A g −1 . We have also developed micro batteries and pouch cells to verify the feasibility of the structure. This work provides an innovative strategy for iodine batteries energy storage system.
✓ 已验证
产品关联
DOI
高影响因子
Batteries & Supercaps
·
2025
·
IF 4.7
Zenghao Li,Yujing Sheng,Xingfa Gao,Yuzhen Huang,Zhenzhong Han,Ruliang Zhang,Yinglun Sun
Graphical In this work, an intrinsiclly antifreezing hydrogel based on amphiphilic copolymer was designed, whose freezing point can be as low as −30 °C without adding any organic solvents and salts. By soaking the hydrogel in Zn(ClO 4 ) 2 solution to serve as the electrolyte of flexible zinc ion hybrid capacitor, the device achieved excellent electrochemical performance at −50 °C. Flexible zinc ion hybrid capacitors (ZIHCs) have attracted extensive research interest by virtue of their high safety and low cost. However, their low-temperature application remains limited due to the freeze of hydrogel electrolytes. Herein, we prepared an intrinsiclly antifreezing amphiphilic copolymer hydrogel based on hydrophilic monomer 2-Hydroxyethyl acrylate and hydrophobic monomer 1H, 1H, 2H, 2H perfluorooctyl methacrylate. Thanks to the hydrogen bond destruction effect of the hydrophilic units and the nano-confinement effect of the hydrophobic units, the hydrogel exhibited a freezing point as low as −30 °C, which was significantly lower than that of hydrogel prepared using pure hydrophilic monomers. In addition, the hydrogel also showed excellent adhesion performance, which contributed to the assembly of device and prevented layer-to-layer slippage during the device use. By soaking the hydrogel in Zn(ClO 4 ) 2 solution to serve as the electrolyte of the ZIHC, the device achieved excellent electrochemical performance at −50 °C. This work provides a new path for the design of antifreeze hydrogel electrolytes for ZIHCs.
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2024
·
IF 13
Xiuli Chen,Yusheng Gong,Min Li,Qi Zeng,Rengui Xu,Xiaolong Li,Xiang Lu,Shang Gong,Jiarong Xu,Guanyue Li,Jingwen Yang,Wenhao Jiao,Jiajing Liu,Yuan Liu,Xinting Liang,Linxi He,Fei Xiao,Wei Chen
Anastomotic leakage (AL) is a pervasive and risky postoperative complication that presently features inaccessible prevention, delayed diagnosis, and intractable remediation, resulting in distressing morbidity and mortality. Herein an interior/exterior collaboration-enhanced neoteric intestinal anastomosis (IECIA) is developed, which consists of an interior hydrogel-based protective barrier adhering to mucosa, and exterior synergistic leakage-prevention safeguard sutured to serosa, for multi-tiered leakage complication management. Noticeably, the hydrogel barrier protects anastomosis stoma against injurious stimulation from digestive liquid, consequently reducing leakage risk effectively and comfortably in place of painful gastric tube insertion. The exterior safeguard encompassing fluorescein-loaded hydrogel and electrospun film functions as a secondary defense, exhibiting critical leakage-prevention capability to refrain from lethal intra-abdominal infection. Meanwhile, fluorescein is released to the enteric cavity for following detection within the excrement in case anastomotic leakage occurs, achieving presymptomatic alarming in providing valuable prompts for timely clinical intervention. Importantly, IECIA has been investigated in realistic in vivo end-to-end intestinal anastomosis scenarios as well as simulated leakage models, which present satisfactory postoperative recovery of gastrointestinal functions and systematic indexes. Moreover, the IECIA system is endowed with guaranteed biocompatibility, effective durability, comprehensibility for surgical operation, comfort, and compliance for patients, which demonstrates precious value for clinical translation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Nano
·
2024
·
IF 15.8
Sen Jin,Zuhao Shi,Ruige Wang,Yitong Guo,Libo Wang,Qianku Hu,Kai Liu,Neng Li,Aiguo Zhou
Highly active and low-cost co-catalysts have a positive effect on the enhancement of solar H2 production. Here, we employ two-dimensional (2D) MBene as a noble-metal-free co-catalyst to boost semiconductor for photocatalytic H2 production. MoB MBene is a 2D nanoboride, which is directly made from MoAlB by a facile hydrothermal etching and manual scraping off process. The as-synthesized MoB MBene with purity >95 wt % is treated by ultrasonic cell pulverization to obtain ultrathin 2D MoB MBene nanosheets (∼0.61 nm) and integrated with CdS via an electrostatic interaction strategy. The CdS/MoB composites exhibit an ultrahigh photocatalytic H2 production activity of 16,892 μmol g–1 h–1 under visible light, surpassing that of pure CdS by an exciting factor of ≈1135%. Theoretical calculations and various measurements account for the high performance in terms of Gibbs free energy, work functions, and photoelectrochemical properties. This work discovers the huge potential of these promising 2D MBene family materials as high-efficiency and low-cost co-catalysts for photocatalytic H2 production.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）