Nano Research
·
2021
·Vol. 15
·期 2
·1039-1046
·
IF 8.897
Xu Tong,Liang Jie,Wang Yuanyuan,Li Shaoxiong,Du Zhaobai,Li Tingshuai,Liu Qian,Luo Yonglan,Zhang Fang,Shi Xifeng,Tang Bo,Kong Qingquan,Asiri Abdullah M.,Yang Chun,Ma Dongwei,Sun Xuping
Electrocatalytic N 2 reduction provides an attractive alternative to Haber-Bosch process for artificial NH 3 synthesis. The difficulty of suppressing competing proton reduction, however, largely impedes its practical use. Herein, we design a hydrophobic octadecanethiol-modified Fe 3 P nanoarrays supported on carbon paper (C18@Fe 3 P/CP) to effectively repel water, concentrate N 2 , and enhance N 2 -to-NH 3 conversion. Such catalyst achieves an NH 3 yield of 1.80 × 10 −10 mol·s −1 ·cm −2 and a high Faradaic efficiency of 11.22% in 0.1 M Na 2 SO 4 , outperforming the non-modified Fe 3 P/CP (2.16 × 10 −11 mol·s −1 ·cm −2 , 0.9%) counterpart. Significantly, C18@Fe 3 P/CP renders steady N 2 -fixing activity/selectivity in cycling test and exhibits durability for at least 25 h. First-principles calculations suggest that the surface electronic structure and chemical activity of Fe 3 P can be well tuned by the thiol modification, which facilitates N 2 electroreduction activity and catalytic formation of NH 3 .
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 14
·19380-19389
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IF 2.478
Zhao Yingying,Zhang Jiejing,Fu Wuyou
Organic pollutant is an environmentally harmful and ubiquitous aquatic pollutant with extensive production and application. In this study, a unique novel TiO 2 -based dual-sensitized heterojunction photocatalyst (PbS/CdS/TiO 2 ) was successfully obtained by one step hydrothermal method, chemical bath deposition (CBD) method and ionic layer adsorption and reaction (SILAR) method. Scanning electron microscopy, X-ray photoelectron spectroscopy, transmission electron microscopy and energy dispersive spectrometer characterized the composition. PbS/CdS was successfully decorated on the surface of TiO 2 nanosheet array. As a stable catalyst with wide-spectrum (300–800 nm) optical response, excited electron–hole pairs of PbS/CdS/TiO 2 could apply in degrading organic pollutants. Successfully, the degradation efficiency of PbS(5 C)/CdS(30 min)/TiO 2 nanocomposites reached 99.9% under visible light, which was 5 times over pure TiO 2 . This ternary heterostructured materials will be well-promising photocatalysts.
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RESEARCH ON CHEMICAL INTERMEDIATES
·
2021
·Vol. 47
·期 10
·4051-4066
·
IF 2.914
Chen Rong,Yi Guohui,Wu Songshuai,Meng Chuangang
Well-dispersed Au–Pt alloyed bimetallic nanoparticles are synthesized using chlorogenic acid as the only reducing agent and stabilizer to reduce Au/Pt precursors successively has been presented here. The shapes of Au–Pt bimetallic nanoparticles are controlled by changing the sequence of successive reduction: the spherical shape in the sequence of Pt precursor reduced prior to Au precursor, and the flower shape by reversing the sequence. The sizes of Au–Pt bimetallic nanoparticles can be tuned by changing the molar ratios of the precursors to chlorogenic acid, and the average size of Au–Pt bimetallic nanoparticles decreased or increased with an increase in chlorogenic acid concentration in different sequence of successive reduction. Additionally, the high antioxidant activity of Au–Pt bimetallic nanoparticles was verified by in vitro radical scavenging assays. Our results show that chlorogenic acid is an excellent reducing and capping agent for the controlled synthesis and stabilization of Au–Pt bimetallic nanoparticles, which could be extended to reduce other metal precursors for synthesizing bimetallic and trimetallic nanoparticles. These shape-controlled and size-tunable Au–Pt bimetallic nanoparticles by chlorogenic acid will expand their biomedical applications in future. Graphic abstract
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CELLULOSE
·
2021
·Vol. 28
·期 11
·7465-7481
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IF 5.044
Xiao Mengyuan,Guo Yingbin,Zhang Jiayue,Liu Yansong,Ren Yuanlin,Liu Xiaohui
Ammonium salt of diethylene triamine penta methylene phosphonic acid (ADTPMPA), a novel flame retardant, was synthesized and grafted on the lyocell fabric to obtain a kind of flame retardant lyocell fabric (FR-lyocell). Then FR-lyocell was coated by Ag nanoparticles (Ag NPs) to fabricate flame retardant and antibacterial lyocell fabric (FR-Ag-lyocell). The elemental composition, surface morphology, combustion behavior and antibacterial activity of the lyocell fabric before and after modification were investigated. The flame retardant and antibacterial mechanism of FR-Ag-lyocell fabric was also analyzed. The limiting oxygen index (LOI) values of FR-Ag-lyocell fabric before and after 20 laundering cycles (LCs) reached 44.8% and 31.3%, respectively. The treated lyocell fabric possessed lower peak of heat release rate (pHRR) and total heat release (THR) values compared with control lyocell fabric. The FR-Ag-lyocell fabric exhibited excellent antimicrobial ability against Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ), even after 10 LCs. These results indicated that FR-Ag-lyocell fabric had durable flame retardant and antibacterial properties. Graphic abstract
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Drug Delivery and Translational Research
·
2021
·Vol. 12
·期 3
·603-614
·
IF 4.617
Shi Feng,Chen Lin,Wang Yaping,Liu Jing,Adu-Frimpong Michael,Ji Hao,Toreniyazov Elmurat,Wang Qilong,Yu Jiangnan,Xu Ximing
The objective of this study was to fabricate a novel drug delivery system using Soluplus® (polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer) and glycyrrhizic acid to improve solubility, bioavailability, and anti-hyperuricemic activity of aloe emodin (AE). The AE-loaded mixed micelles (AE-M) were prepared by thin-film hydration method. The optimal AE-M contained small-sized (30.13 ± 1.34 nm) particles with high encapsulation efficiency (m/m, %) of 90.3 ± 1.08%. The release rate of AE increased in the micellar formulation than that of free AE in the four media (DDW, pH 7.0; phosphate buffer solution, pH 7.4; phosphate buffer solution, pH 6.8; and hydrochloric acid aqueous solution, pH 1.2). In comparison to free AE, the pharmacokinetic study of AE-M showed that its relative oral bioavailability increased by 3.09 times, indicating that mixed micelles may promote gastrointestinal absorption. More importantly, AE-M effectively reduced uric acid level by inhibiting xanthine oxidase (XOD) activity in model rats. The degree of ankle swelling, serum levels of interleukin (IL)-1, and IL-6-related inflammatory factors levels all decreased in the gouty arthritis model established via monosodium urate (MSU) crystals. Taken together, the AE-M demonstrated the potential to improve the bioavailability, anti-hyperuricemic activity, and anti-inflammation of AE. Graphical abstract
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PubMed
高影响因子
MOLECULAR MEDICINE
·
2021
·Vol. 27
·期 1
·1-16
·
IF 6.354
Cui Jing,Guo Yao,Wu Heshui,Xiong Jiongxin,Peng Tao
Background Gemcitabine (GEM) resistance remains a significant clinical challenge in pancreatic cancer treatment. Here, we investigated the therapeutic utility of everolimus (Evr), an inhibitor of mammalian target of rapamycin (mTOR), in targeting the Warburg effect to overcome GEM resistance in pancreatic cancer. Methods The effect of Evr and/or mTOR overexpression or GEM on cell viability, migration, apoptosis, and glucose metabolism (Warburg effect) was evaluated in GEM-sensitive (GEM sen ) and GEM-resistant (GEM res ) pancreatic cancer cells. Results We demonstrated that the upregulation of mTOR enhanced cell viability and favored the Warburg effect in pancreatic cancer cells via the regulation of PI3K/AKT/mTOR signaling. However, this effect was counteracted by Evr, which inhibited aerobic glycolysis by reducing the levels of glucose, lactic acid, and adenosine triphosphate and suppressing the expression of glucose transporter 1, lactate dehydrogenase-B, hexokinase 2, and pyruvate kinase M2 in GEM sen and GEM res cells. Evr also promoted apoptosis by upregulating the pro-apoptotic proteins Bax and cytochrome-c and downregulating the anti-apoptotic protein Bcl-2. GEM was minimally effective in suppressing GEM res cell activity, but the therapeutic effectiveness of Evr against pancreatic cancer growth was greater in GEM res cells than that in GEM sen cells. In vivo studies confirmed that while GEM failed to inhibit the progression of GEM res tumors, Evr significantly decreased the volume of GEM res tumors while suppressing tumor cell proliferation and enhancing tumor apoptosis in the presence of GEM. Conclusions Evr treatment may be a promising strategy to target the growth and activity of GEM-resistant pancreatic cancer cells by regulating glucose metabolism via inactivation of PI3K/AKT/mTOR signaling.
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PubMed
高影响因子
Journal of Analytical Science and Technology
·
2021
·Vol. 12
·期 1
·1-9
·
IF 2.769
Dong Bin,Fan Qian,Li Ming,Huan Yanfu,Feng Guodong,Shan Hongyan,Fei Qiang
In this study, N-(4-aminobutyl)-N-ethylisoluminol (ABEI) was used as an energy donor, while sodium fluorescein was used as an enhancer and energy acceptor, which resulted in it producing resonance energy transfer and greatly increasing the strength of chemiluminiscence (CL). When horseradish peroxidase (HRP) is added, hydrogen peroxide (H2O2) will quickly separate into hydroxyl radicals (·OH) and superoxide ions (O2·−). If tyrosine (Tyr) is present in the system, the hydroxyl group on the benzene ring of Tyr robs ·OH and O2·− in the CL system, thereby reducing the intensity of CL. Based on this phenomenon, a luminescence system of ABEI and sodium fluorescein system was established to detect Tyr for the first time. This method has an ultra-low detection limit and a wide linear range, and is cheap and easy to operate. Under various optimal conditions, the linear range is from 3.0×10−8 to 3.0×10−5 mol/L, and the limit of detection is 2.4×10−8 mol/L. It has been successfully used in the detection of dairy products with satisfactory results.
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KOREAN JOURNAL OF CHEMICAL ENGINEERING
·
2021
·Vol. 38
·期 5
·899-905
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IF 3.309
Chen Binglin,Li Jiachen,Feng Yunchao,Le Kai,Zai Yuxia,Tang Xing,Sun Yong,Zeng Xianhai,Lin Lu
Algal biomass was converted into 5-aminolevulinic acid (5-ALA) in five chemical steps: conversion to 5-(chloromethyl)furfural (5-CMF), ammoniation, ring-opening (photo-oxidation), reduction, and hydrolyzation. Among them, we mainly focused on the 5-CMF production and the following ammoniation. To our knowledge, the mixed solvent catalytic system of deep eutectic solvent (DES) and low concentration hydrochloric acid is the first reported for the synthesis of 5-CMF from algal biomass, providing a 24.6% 5-CMF yield at 120 °C for 5 h. Potassium phthalimide (KPI) was employed as an ammoniation reagent with superb selectivity and activity instead of conventional sodium azide (NaN 3 ). Optimizing the experimental design, a 23.7% 5-ALA yield along with high purity (>96%) was achieved from 5-CMF, and the total 5-ALA yield was 5.8% from algal biomass. This work provides a green and mild pathway for 5-ALA production from algal biomass.
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Food Analytical Methods
·
2021
·Vol. 14
·期 10
·2076-2087
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IF 3.366
Wang Dan,Yang Yi,Xu Zhigang,Liu Yujian,Liu Zhimin,Lin Tao,Chen Xinglian,Liu Hongcheng
An effective method based on molecularly imprinted polymer solid-phase microextraction (MIP-SPME) to assess the risk of kojic acid (KA) in food was proposed in this work. KA is widely used in the food industry but may have potential hazards, such as carcinogenicity. Herein, theoretical simulation and UV–vis spectrum were applied to investigate the synthesis procedure of MIP. The molecular simulation was in marked contrast with the traditional complicated preparation optimization of MIP-SPME coating. The prepared MIP-SPME fiber coating was a mesoporous material with high porosity, the leading cause of better mass transfer of target analytes in complex media. Furthermore, a novel theoretical simulation method of annealing operation was used to obtain the hydrogen bond interaction force for every possible or even dominate action site in the template-monomer system. In addition, compared to the existing approaches of KA determination, this method exhibited ultralow limits of quantification (0.20 and 0.72 μg L −1 ); it was successfully used for the selective trace detection of KA in wheat flour and starch. The proposed MIP-SPME approach, as a strategy for the risk assessment of KA, is proven to have great stability, high sensitivity and reproducibility.
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INTERNATIONAL JOURNAL OF THERMOPHYSICS
·
2021
·Vol. 42
·期 6
·1-24
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IF 1.608
Liu Ping,Liu Zimin,Zhao Tianxiang,Liu Fei,Liao Quanlan
Densities and viscosities for the binary system of tetraethylene glycol (1) + water (2) at T = (298.15 to 323.15) K were measured as a function of composition under atmospheric pressure. The excess properties, including excess molar volumes ( \(V_{{\text{M}}}^{{\text{E}}}\) ), viscosity deviations (Δ η ), and the excess Gibbs free energy of activation for viscous flow (Δ G * E ) were calculated by using density and viscosity data, respectively. Excess properties indicated that there are hydrogen bonding interactions between tetraethylene glycol and water molecules, which are investigated in detail by FTIR and UV–Vis spectra.
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JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2021
·Vol. 98
·期 3
·497-507
·
IF 2.326
Jia Ke,Bi Zun,Liu Yunfei,Lyu Yinong
Studying electronic structure plays a key role in improving the photoluminescence (PL) properties of materials. Therefore, the electronic structure of YF 3 : x Eu 3+ with different Eu 3+ ions doping concentrations was explored by first-principles calculations based on density functional theory (DFT). As calculated, the YF 3 host had an indirect bandgap of 7.68 eV. From all calculation results we got, the band structure of YF 3 : x Eu 3+ exhibited the smallest direct band gap of 6.54 eV when the value of x was 0.10. This small direct band gap is beneficial to obtain excellent emission intensity. Besides, the morphologies and sizes have a significant influence on the fluorescence intensity of the products. A series of YF 3 : x Eu 3+ phosphors with leaf-like, spindle-like, pecan-like, and granular-like morphologies were obtained by changing the RE 3+ /NaF ratio via a microwave hydrothermal method. At the same time, the formation process of granule-like YF 3 : Eu 3+ was explored through time-dependent experiments. Furthermore, the fluorescence performance of YF 3 : x Eu 3+ was studied in detail. The as-obtained YF 3 : x Eu 3+ can exhibit orange-red emission under ultraviolet excitation because of the magnetic dipole of the 5 D 0 – 7 F 1 transition of Eu 3+ ions. After comparing the luminescence properties of samples with different morphologies, we found that the sample with granule-like morphology had the highest orange-red emission intensity. The experimental result proved that the appropriate Eu 3+ ions doping concentration were x = 0.10, which is highly consistent with the calculation result.
The great orange-red emission intensity was obtained by adjusting the electronic structure and morphology of the YF 3 : x Eu 3+ . The electronic structures of YF 3 : x Eu 3+ can be altered by changing Eu 3+ doping concentrations. The morphologies can be regulated by changing the RE 3+ /NaF ratio. Besides, the formation process of granule-like YF 3 : 0.1Eu 3+ was explored through time-dependent experiments.
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CELLULOSE
·
2021
·Vol. 28
·期 9
·5657-5668
·
IF 5.044
Zhu Enwen,Xu Haiyu,Xie Yuanyuan,Song Yiheng,Liu Dongning,Gao Yujiao,Shi Zhuqun,Yang Quanling,Xiong Chuanxi
Abstract Ionic hydrogels with excellent flexibility and good conductivity have great potential in diverse electric devices. However, it remains challenging to improve the biocompatibility of ionic hydrogels. Here, natural and environment-friendly cellulose nanofiber hydrogels were prepared without adding any organic active materials. The cellulose hydrogel networks with free metal ions (Li + /Ca 2+ /K + ) were obtained by soaking in ion aqueous solution of different concentrations in order to endow tunable conductivity, thus a new kind of transparent ionic hydrogels with both excellent sensing performance obtained by a simple, low-cost and harmless process. The free metal ions locked in the negatively charged nanocellulose network through electrostatic interaction provided adjustable conductivity and sensing performance. Hydrogels doped with 4 mol L −1 lithium ions exhibited the best sensing performance with the conductivity of 4.36 × 10 –4 S cm −1 , and the current response value was as high as 127%. It was worth noting that the strain-sensitive performance of calcium ions was generally excellent even at low temperatures (−30 °C). The antifreezing of the hydrogel improved its service under extreme environment. This kind of hydrogel has great application prospects in artificial intelligence products, such as human healthy monitoring equipment and soft robotics at subzero temperature. Graphic abstract
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危险品化学品经营许可证（带存储）