Nature Communications
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2025
·Vol. 16
·期 1
·9977
·
IF 15.7
Qin Feiyu,Bai Xiaoya,Fang Yue-Wen,Zhu Pengli,Wang Jun,Cheng Pengtao,Wang Dunhui,Hu Lei,Sun Jun,Ding Xiangdong
Giant negative thermal expansion (NTE), defined by volumetric expansion α V
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Journal of Inorganic and Organometallic Polymers and Materials
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2025
·
IF 4.9
Li Huanxuan,Wei Xueheng,Gao Xing,Liu Chen,Li Ning,Xu Chen,Huang Jingang,Liu Xiuyan,Xu Shaodan
The degradation of antibiotics remains a major and persistent challenge in wastewater treatment. This study reports the synthesis of three distinct catalysts from a zeolitic imidazolate framework-67 (ZIF-67) precursor through pyrolysis at 800 °C, namely ZIF-67(Fe)-800, ZIF-67(Co)-800, and ZIF-67(FeCo)-800. Comprehensive characterization (e.g., X-ray diffractometer and transmission electron microscopy analyses) confirmed their graphitic carbon matrix, specific metallic phases, and unique polyhedral morphologies. These catalysts were employed to activate peroxymonosulfate (PMS) for ciprofloxacin (CIP) degradation. Strikingly divergent catalytic performances were observed, with CIP degradation rate constants of 0.0027, 0.0731, and 0.0504 min –1 for ZIF-67(Fe)-800, ZIF-67(Co)-800, and ZIF-67(FeCo)-800, respectively. Furthermore, the bimetallic ZIF-67(FeCo)-800 demonstrated consistently inferior performance in activating both peroxydisulfate and sodium percarbonate compared to PMS, resulting in significantly lower CIP degradation rates of 52% and 87%, respectively. Mechanistic investigations using electron paramagnetic resonance and quenching tests revealed that hydroxyl radical ( · OH), sulfate radical (SO 4 •− ), and singlet oxygen ( 1 O 2 ) were the dominant reactive species in both the ZIF-67(Fe)-800/PMS and ZIF-67(Co)-800/PMS systems. In contrast, the ZIF-67(FeCo)-800/PMS system operated via a distinct pathway, primarily generating SO 4 •− , accompanied by · OH, 1 O 2 , and superoxide radicals (O 2 •− ). Notably, H 2 PO 4 − and HCO 3 − exhibited strong inhibitory effects on CIP degradation, while SO 4 2− and CH 3 COO − led to modest rate enhancements. Overall, this work provides a rational framework for designing MOF-derived catalysts and highlights their potential for application in advanced oxidation processes aimed at removing pharmaceutical pollutants.
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METABOLIC BRAIN DISEASE
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2025
·Vol. 40
·期 5
·1-13
·
IF 3.5
Huang Ping,Sun Hao,Wang Yan,Wang Ning
Background . The post-stroke inflammatory response denotes the inflammatory damage inflicted upon brain tissue following stroke. Plasma fibrinogen (FIB) can permeate the compromised blood-brain barrier (BBB) after ischemic stroke, leading to the activation of the NLRP3 inflammasome. Tong-Qiao-Huo-Xue-Decoction (TQHXD), a traditional formula used to promote blood circulation and resolve blood stasis, has shown potential in this context. Nevertheless, the precise therapeutic mechanisms of TQHXD in mitigating cerebral ischemia-reperfusion injury remain to be fully elucidated. Objective . To examine the reparative effects and underlying mechanisms of TQHXD-CSF on inflammatory damage in BV-2 cells subjected to oxygen and glucose deprivation/reoxygenation (OGD/R) injury. Methods . To establish an in vitro model of OGD/R injury and an inflammatory BV-2 cells model induced by FIB. The protective effects of TQHXD-CSF on OGD/R-injured cells were verified using CCK-8 and LDH assays. Immunofluorescence, SEM, Western blotting, and CHIP-PCR were employed to confirm that TQHXD reduces the inflammatory response by downregulating FIB levels. Pull-down and co-immunoprecipitation (CO-IP) assays were conducted to detect the interaction between FIB and NLRP3. Results . TQHXD-CSF can significantly inhibit the abnormal increase in LDH levels induced by OGD/R, enhance cell viability, and mitigate cell pyroptosis. Additionally, TQHXD-CSF reversed the marked upregulation of FIB, NLRP3, and GSDMD fluorescence intensity and protein expression caused by the FIB inflammation model, demonstrating an effect comparable to that of lumbrokinase, a fibrinolytic agent for FIB. Furthermore, it notably reduced the acetylation of H3 and H4 in the NLRP3 promoter. Importantly, the pull-down and CO-IP results indicated a robust binding affinity between FIB and NLRP3. Conclusion . TQHXD-CSF can inhibit inflammation by downregulating the FIB-NLRP3 pathway and exert a protective effect on BV-2 cells under OGD/R and FIB inflammatory injury. Graphical abstract
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-10
·
IF 15.7
Li Weipeng,Xu Weizhuo,Sun Zhaopeng,Tang Linning,Xu Guohao,He Xinyue,Deng Yulin,Sun Wei,Zhou Bingjie,Song Jianfei,Liu Wei
As a promising stationary energy storage device, aqueous redox flow battery (ARFB) still faces the challenge of low open-circuit voltage, due to the limitation of the potential of water splitting (1.23 V theoretically). Herein, we present a low potential anolyte design by using Na substituted phosphotungstic acid (3Na-PW 12 ) for an aqueous redox flow battery with the high open-circuit voltage up to 2.0 V. The 3Na-PW 12 can store 5 electrons in the charging process and simultaneously capture Na + or protons from the dissociation of water, resulting in the increase of electrolyte pH to 11. Because of the high pH value, the hydrogen evolution reaction (HER) is highly suppressed, and the 3Na-PW 12 is partially degraded into a lacunary structured PW 11 with extremely low potential down to −1.1 V (vs. SHE). After discharging, the captured protons are re-released into the solution, therefore, pH and the structure of 3Na-PW 12 are recovered. Based on the cyclic pH change and self-regulation process of 3Na-PW 12 in the charge and discharge process, the aqueous flow battery offered a high-power density of 200 mW cm −2 and 160 mW cm −2 coupled with Br 2 /Br − and I 2 /I − catholyte respectively.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2025
·Vol. 36
·期 13
·1-11
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IF 2.8
Wang Zhenyang,Zhang Hui,Chen Zhixing,Zhang Xingyue,Zhou Yuanming,Mei Fei
The recent attention accorded to perovskite light-emitting diodes (PeLEDs) can be attributed to their exceptional optoelectronic characteristics. In this paper, the perovskite emissive layer (EML) modified by two-dimensional material Ti 3 C 2 T x MXene was explored with the aim of improving the morphology of perovskite films and the luminescence efficiency of PeLEDs. A doping concentration of 0.2 mM Ti 3 C 2 T x yielded optimal results for the PeLEDs, with a maximum luminance of 8317 cd/m 2 and a maximum current efficiency (CE) of 6.63 cd/A, representing a 200 and 103% enhancement, respectively, in comparison to the reference device lacking Ti 3 C 2 T x . It has been evidenced that doping Ti 3 C 2 T x MXene plays the role of enhancing the morphology of perovskite films and passivating the defects present in these films. Furthermore, Ti 3 C 2 T x facilitates the exciton recombination efficiency, enhances the radiative recombination of the emissive layer and thus improves the optoelectronic efficiency of the PeLEDs. This work presents novel concepts for the utilization of MXene in PeLEDs.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-12
·
IF 15.7
Wang Shijie,Liang Kang,Zhao Hongshun,Wu Min,He Junfeng,Wei Peng,Ding Zhengping,Li Jianbin,Huang Xiaobing,Ren Yurong
High-capacity power battery can be attained through the elevation of the cut-off voltage for LiNi 0.83 Co 0.12 Mn 0.05 O 2 high-nickel material. Nevertheless, unstable lattice oxygen would be released during the lithium deep extraction. To solve the above issues, the electronic structure is reconstructed by substituting Li + ions with Y 3+ ions. The dopant within the Li layer could transfer electrons to the adjacent lattice oxygen. Subsequently, the accumulated electrons in the oxygen site are transferred to nickel of highly valence state under the action of the reduction coupling mechanism. The modified strategy suppresses the generation of oxygen defects by regulating the local electronic structure, but more importantly, it reduces the concentration of highly reactive Ni 4+ species during the charging state, thus avoiding the evolution of an unexpected phase transition. Strengthening the coupling strength between the lithium layers and transition metal layers finally realizes the fast-charging performance improvement and the cycling stability enhancement under high voltage.
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npj Science of Food
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2025
·Vol. 9
·期 1
·1-9
·
IF 7.8
Zhu Yan,Du Wangli,Cui Jian,Shao Hong,Guo Yakun,Tang Changyu,Xu Run
In this work, we adopt “hyperthermal hydrogen-induced cross-linking (HHIC) technology” to fix an interfacial control layer of polyacrylic acid (PAA) on polylactic acid (PLA) to improve the adhesion and integrity of the permeation barrier film, and meanwhile, the HHIC treatment causes no measurable damage to the functional groups of PAA and PLA. Consequently, the oxygen transmission rate decreases from 150.00 to 0.50 ml m −2 day −1 (a reduction of 99.7%), which is less than one tenth of the best value reported, and that the water vapour transmission rate decreases from 32.93 to 16.25 g m −2 day −1 (a reduction of 50.7%), which is slightly higher than the best value reported (3.8% higher). Our work shows that the HHIC technology used in this study provides an efficient way to improve the oxygen and water vapour blocking ability of PLA and may help in improving the quality of other polymer heterointerfaces in the future.
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APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
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2025
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IF 3.3
Zhang Xiuju,Nie Xiaowei,Yu Wenxiao,Du Guanchao,Liu Shaoming,Song Yewen
MicroRNA (miRNA) has emerged as a potential diagnostic marker for malignancies, such as prostate cancer; yet, few analytical approaches have been established for the simple and effective identification and quantification of miRNA. We depict here a fluorescent dumbbell probe utilizing DNA-silver nanoclusters (DNA-AgNCs) to facilitate the simple and label-free quantification of miRNA. The fluorescent probe was methodically engineered using a double-flapped dumbbell structure, wherein the 5′ flap was synthesized using DNA-AgNCs, and the 3′ flap was extended by a G-rich sequence. The DNA scaffold rigidifies the DNA-AgNCs and the G-rich sequence, bringing them into close contact, which leads to enhanced fluorescence due to the activation of DNA-AgNCs by the G-rich sequence. Upon the introduction of miRNA, the 5′ flap of the probe unfolds, liberating the G-rich sequence from the probe, disrupting the closeness between DNA-AgNCs and the G-rich region, and resulting in decreased fluorescence. The proposed method, by incorporating target recycling and polymerase/endonuclease-assisted cycles, enables sensitive detection of miRNA with a detection limit of 4.2 fM and demonstrates high specificity for monitoring target miRNA in clinical samples, offering a robust platform for miRNA monitoring and disease diagnosis. Graphical
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2025
·Vol. 36
·期 15
·1-12
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IF 2.8
Li Meiling,Cao Yongze,Cheng Lihong,Fan Yuhan,Wang Yichao,Li Xiangping,Zhang Xizhen,Chen Baojiu
A series of Er 3+ /Yb 3+ co-doped NaY(WO 4 ) 2 (NYWO) phosphors are prepared by molten salt synthesis (MSS) with Na 2 SO 4 as solvent. The holding temperature, holding time, and solvent-to-solute mass ratio parameters are regulated. The structure, morphology, and luminescence properties of the samples were tested by XRD, SEM, and fluorescence spectrometers, respectively. The lamellar sample is prepared at 900℃ for 5 h when solvent-to-solute is 3, which has the highest pure green upconversion luminescence (UCL) intensity under 980 nm laser excitation. It is demonstrated that the UCL intensity of the samples prepared by MSS is higher than that of solid sintered samples. The maximum absolute sensitivity (S A ) and relative sensitivity (S R ) are 0.012184 K⁻ 1 at 507 K and 0.01102 K⁻ 1 at 303 K, respectively. These materials can be used for pure green luminescence displays and temperature sensing.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-16
·
IF 15.7
Gao Yang,Luo Mingdu,Wang Hongmiao,Zhou Zhiwei,Yin Yandong,Wang Ruohong,Xing Beizi,Yang Xiaohua,Cai Yuping,Zhu Zheng-Jiang
Metabolic reactions play important roles in organisms such as providing energy, transmitting signals, and synthesizing biomacromolecules. Charting unknown metabolic reactions in cells is hindered by limited technologies, restricting the holistic understanding of cellular metabolism. Using mass spectrometry-resolved stable-isotope tracing metabolomics, we develop an isotopologue similarity networking strategy, namely IsoNet, to effectively deduce previously unknown metabolic reactions. The strategy uncovers ~300 previously unknown metabolic reactions in living cells and mice. Specifically, we elaborately chart the metabolic reaction network related to glutathione, unveiling three previously unreported reactions nestled within glutathione metabolism. Among these, a transsulfuration reaction, synthesizing γ-glutamyl-seryl-glycine directly from glutathione, underscores the role of glutathione as a sulfur donor. Functional metabolomics studies systematically characterize biochemical effects of previously unknown reactions in glutathione metabolism, showcasing their diverse functions in regulating cellular metabolism. Overall, these newly uncovered metabolic reactions fill gaps in the metabolic network maps, facilitating exploration of uncharted territories in cellular biochemistry.
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JOURNAL OF MATERIALS SCIENCE
·
2025
·
IF 3.9
Wang Xi,Wu Juan,Sun Haibin,Lu Bingyan,Huang Jingjing,Liu Qiaoling,Li Tingting
Biofilms pose a significant challenge to public health, fostering persistent infections that are notoriously difficult to eradicate. Their resilience stems partly from the inadequate penetration of conventional antibacterial agents into these structured microbial communities. To address this issue, we have developed a novel magnetite iron oxide Janus nanoparticles (JNPs), harnessing the magnetic field assistance for targeted biofilm elimination. In which, natural tannic acid (TA) and chitosan (CS) were coated on IONPs for improved antibacterial property and biocompatibility. Subsequently, the surfaces were functionalized with epoxy chloropropane and butanediamine, creating anchor points for the deposition of silver nanoparticles (AgNPs). Subsequently, AgNPs were embedded via an in situ reduction process, utilizing polyvinyl pyrrolidone (PVP) to precisely control the morphology of the Ag-armed magnetite JNPs. Remarkably, IONPs@BCS/Ag exhibited dual-responsive release characteristics, sensitively adjusting their Ag + release in response to both oxygen levels and pH variations within the biofilms microenvironment. This system leveraged both stimulus-responsiveness and magnetic guidance to deliver exceptional antimicrobial performance against both planktonic bacteria and established biofilms. Critically, the superparamagnetic nature of IONPs@BCS/Ag enabled enhanced penetration into biofilms under an external magnetic field, facilitating the efficient delivery of AgNPs. Furthermore, the sustained release of Ag + triggered by low pH and oxygen levels within the biofilm triggered the generation of reactive oxygen species (ROS), which not only accelerated the decomposition of the biofilm matrix but also disrupted the integrity of microbial communities. In summary, the IONPs@BCS/Ag magnetite JNPs, augmented by an external magnetic field, demonstrated enhanced anti-biofilm capabilities, offering immense potential as a potent weapon against biofilm-associated infections. Graphical abstract
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JOURNAL OF MATERIALS SCIENCE
·
2018
·Vol. 54
·期 5
·3795-3804
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IF 2.993
Song Lixin,Jing Wanru,Chen Jingjing,Zhang Shouren,Zhu Yuqing,Xiong Jie
The light response range, reusability, and durability of photocatalyst are the key issues for its practical application. To address these problems, the C-doped TiO 2 /carbon nanofibrous (CTCNF) film with incorporation of C-doped TiO 2 nanoparticles into carbon nanofibers was prepared by electrospinning and calcination (pre-oxidation and carbonization). All the obtained CTCNF films exhibited a promising light absorption in ultraviolet–visible region. With optimization of carbonization temperature, the CTCNF film carbonized at 800 °C (CTCNF-800) showed a strongest light absorption. Consequently, the CTCNF-800 possessed a highest photocatalytic degradation efficiency of 94.2% for degradation of rhodamine B. In addition, the CTCNF-800 possessed excellent flexibility and deserved mechanical strength, and hence, the CTCNF-800 could be easily segregated from solution and recycled. Satisfyingly, its degradation efficiency still exceeded 92% after using for six cycles, implying that the CTCNF had excellent reusability and well stability. Besides, the degradation efficiency was over 90% after the CTCNF-800 kept in air without illumination for 1 year, indicating its outstanding durability. The CTCNF film photocatalyst demonstrates tremendous potential in practical application for purification of wastewater.
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