NEW CARBON MATERIALS
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2022
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IF 3.7
Mei-li Liu,Xiang Long,Hai-yan Tang,Xin-hang Fan,Chao-yi Chen,Jiao-jing Shao
The electrochemical properties of graphene-polyaniline (PANI) hybrids are largely determined by their microstructures and the distribution of PANI on the graphene network. Uniform hybridization of each component is critical to avoid the re-stacking of the graphene sheets and the agglomeration of PANI nanoassemblies during the use of the hybrids. Conventional strategies, such as layer-by-layer assembly or electrochemical in-situ polymerization, involve intricate procedures, making it difficult to achieve the large-scale production of the hybrids. We report a completely miscible cosolvent consisting of N, N-dimethylformamide and water that solves this problem and was used to produce graphene-PANI hybrid flexible fibers. It was found that the composite fiber had a homogeneous microstructure with PANI nanoassemblies uniformly distributed on the graphene sheets, and had outstanding electrochemical properties, much better than the counterpart fabricated using only water as the solvent. The work proposes a universal but simple strategy to achieve the mass production of graphene-PANI hybrids or similar materials with uniform hybridization of the two components.
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高影响因子
CHINESE JOURNAL OF CATALYSIS
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2021
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IF 8.271
Yan-Cheng Hu,Ying Li,Ding-Wei Ji,Heng Liu,Hao Zheng,Gong Zhang,Qing-An Chen
C2 prenylated indoles are widespread in a variety of bioactive natural alkaloids. Therefore, the selective installation of prenyl group at C2 position of NH indoles is of great significance. However, the known protocols generally require a multi-step procedure and stoichiometric promoters. Herein we develop a one-step C2 prenylation of NH indole with cheap tert- prenyl alcohol enabled by acid catalysis. Salient features include good regioselectivity, step- and atom-economy, broad substrate scope, and simple catalytic system. The mechanistic investigations demonstrate that both C2 prenylation and C3 prenylation/migration pathways are engaged in the reaction. Notably, this practical strategy can be applied to the late-stage diversification of tryptophan-based peptides and concise synthesis of tryprostatin B.
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高影响因子
Chinese Journal of Natural Medicines
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2021
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IF 3
Di ZHANG,Bing YANG,Shi-Quan CHANG,Sheng-Suo MA,Jian-Xin SUN,Lin YI,Xing LI,Hui-Mei SHI,Bei JING,Ya-Chun ZHENG,Chun-Lan ZHANG,Feng-Guo CHEN,Guo-Ping ZHAO
This study was to investigate the protective effect of paeoniflorin (PF) on hydrogen peroxide-induced injury. Firstly, “SMILES” of PF was searched in Pubchem and further was used for reverse molecular docking in Swiss Target Prediction database to obtain potential targets. Injury-related molecules were obtained from GeenCards database, and the predicted targets of PF for injury treatment were selected by Wayne diagram. For mechanism analysis, the protein-protein interactions were constructed by String, and the KEGG analysis was conducted in Webgestalt. Then, cell viability and cytotoxicity assay were established by CCK8 assay. Also, the experimental cells were allocated to control, model (200 μmol·L −1 H 2 O 2 ), SB203580 10 μmol·L −1 (200 μmol·L −1 H 2 O 2 + SB203580 10 μmol·L −1 ), PF 50 μmol·L −1 (200 μmol·L −1 H 2 O 2 + PF 50 μmol·L −1 ), and PF 100 μmol·L −1 (200 μmol·L −1 H 2 O 2 + PF 100 μmol·L −1 ) groups. We measured the intracellular ROS, Hoechst 33258 staining, cell apoptosis, the levels of Bcl-xl, Bcl-2, Caspase-3, Cleaved-caspase3, Cleaved-caspase7, TRPA1, TRPV1, and the phosphorylation expression of p38MAPK. There are 96 potential targets that may be associated with PF for injury treatment. Then, we chose the “Inflammatory mediator regulation of TRP channels” pathway for the experimental verification from the first 10 KEGG pathway. In experimental verification, H 2 O 2 decreased the cell viability moderately ( P < 0.05), and 100 μmol·L −1 PF increased the cell viability significantly ( P < 0.05). Depending on the difference of intracellular ROS fluorescence intensity, PF inhibited H 2 O 2 -induced reactive oxygen species production in Schwann cells. In Hoechst 33258 staining, PF reversed the condensed chromatin and apoptotic nuclei following H 2 O 2 treatment. Moreover, Flow cytometry results showed that PF could substantially inhibit H 2 O 2 induced apoptosis ( P < 0.05). Pretreatment with PF obviously reduced the levels of Caspase3, Cleaved-caspase3, Cleaved-caspase7, TRPA1, TRPV1, and the phosphorylation expression of p38MAPK after H 2 O 2 treatment ( P < 0.05), increased the levels of Bcl-2, and Bcl-xl ( P < 0.05). PF inhibited Schwann cell injury and apoptosis induced by hydrogen peroxide, which mechanism was linked to the inhibition of phosphorylation of p38MAPK.
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PubMed
高影响因子
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
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2021
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IF 2.917
Lei HUANG,Zhi-hui YANG,LÜ-ji YAN,Sikpaam Issaka ALHASSAN,Hai-yin GANG,Ting WANG,Hai-ying WANG
2D carbon ribbon/Al 2 O 3 was synthesized with two-dimensional metal organic frameworks 2D-MOFs as precursors using the solvothermal and calcination methods. Batch experiments of adsorption parameters such as pH, liquid/solid ratio, adsorption kinetics, adsorption thermodynamics, and anions competitions were investigated to understand the adsorptive behavior of fluoride on carbon ribbon/Al 2 O 3 and nitrogen-doped carbon ribbon/Al 2 O 3 . The adsorption of fluoride on carbon ribbon/Al 2 O 3 could be described as the chemical and multilayer adsorption, while the adsorption of fluoride on nitrogen-doped carbon ribbon/Al 2 O 3 followed the chemical and monolayer adsorption phenomenon. The fluoride on nitrogen-doped carbon ribbon/Al 2 O 3 had a much faster adsorption rate of 3.1×10 −7 m/s than carbon ribbon/Al 2 O 3 , which was 1.2×10 −7 m/s. The nitrogen-doping on carbon ribbon enhances structural defects and improves the adsorption performance of fluoride. Also, the diacetylene linkages (—C≡C—) and pyridinic-N were studied to understand their influences on removing fluoride. The result indicates that carbon ribbon and nitrogen-doped ribbon could serve as good adsorbents for removing fluoride.
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高影响因子
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
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2021
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IF 1.134
Xiao-Xuan ZHANG,Wu-Bo CHU,Nan JIANG,He LI
Serum albumin is the most abundant protein in mammalian plasma and is often used as a model to understand the adhesion behavior of proteins on surfaces. Attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) is used to non-destructively and dynamically detect the chemical change information between the protein and the surface during the adhesion process, which is especially suitable for in-situ measurement of samples in water. Therefore, the adhesion of bovine serum albumin (BSA) on the surface in H 2 O and D 2 O is investigated by ATR-FTIR technology, which effectively avoids the interference of the characteristic peak of deformation vibration of liquid H 2 O (1645 cm −1 ) on the amide I band of BSA. Sodium alginate, a polysaccharide widely present in the ocean, is introduced into the BSA solution to explore the changes in the adhesion process of proteins on the surface of ZnSe, and polarized ATR-FTIR spectra are also collected to study the adhesion orientation of BSA. Sodium alginate presents a negative effect on the adhesion of BSA on the surface and there is no specific orientation of BSA on the surface.
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高影响因子
CHINESE JOURNAL OF CATALYSIS
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2020
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IF 6.146
Feiyue Ge,Shuquan Huang,Jia Yan,Liquan Jing,Feng Chen,Meng Xie,Yuanguo Xu,Hui Xu,Huaming Li
Expanding the optical absorption range of photocatalysts is still a key endeavor in graphitic carbon nitride (g-C 3 N 4 ) studies. Here, we report on a novel thiophene group extending the optical property, which is assigned to n-π* electronic transitions involving the two lone pairs on sulfur (TLPS). The as-prepared samples, denoted as CN-ThA x (where x indicates the amount of ThA added, mg), showed an additional absorption above 500 nm as compared to pristine g-C 3 N 4 . Further, the thiophene group enhanced charge carrier separation to suppress e − /h + pair recombination. The experimental results suggest that the thiophene group can obstruct the polymerization of melem to generate a large plane, thus exposing the lone electron pairs on the sulfur. The photocatalytic activity was evaluated in the decomposition of bisphenol A and H 2 evolution. Compared with g-C 3 N 4 , the optimized CN-ThA 30 sample led to a 6.6- and 2-fold enhancement of the degradation and H 2 generation rates, respectively. The CN-ThA 30 sample allowed for synchronous H 2 production and BPA decomposition.
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高影响因子
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
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2020
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IF 0.936
Wen-Nan FENG,Jin HE,Si-Ying LI,Dan YANG,Hong-Na LI,Guo-Cheng YANG,Qiang FU,Yu-Ping SHAN
In recent years, exosomes as the intercellular vehicles have received extensive attention for their fundamental roles in biosystem and as novel biomarkers for early detection and therapeutic applications. It has been demonstrated that anti-CD63 can effectively target exosomes from cancer cells. In this work, multifunctional nanoelectrode-nanopore nanopipettes (MNNPs) were prepared to detect exosomes secreted from human cervical cancer cells (HeLa cells) at the single-entity level using the nanopore- based resistive pulse sensing technique. Synthetic liposomes were also measured for comparison. By modifying the anti-CD63 on the carbon nanoelectrode surface near the nanopore, the detected current signals were very different from the signals from the non-modified MNNPs. The differences were induced by the specific interactions between anti-CD63 and the membrane protein CD63 at the surface of exosomes. No obvious differences were observed when liposomes were tested. Furthermore, by utilizing micromanipulation technology, the position of the nanopipette tip could be accurately located, which enabled monitoring the secretion of exosomes from individual cells in a real-time manner. In the control experiment, the probe-to-cell distance was optimized and the HeLa cells incubated with exosomes inhibitor (GW4869) were tested by MNNPs. These significantly reduced translocation signals proved that anti-CD63 modified MNNPs were competent for exosomes detection in complex cellular environments.
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高影响因子
CHINESE JOURNAL OF CATALYSIS
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2019
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IF 4.914
Ruowen Liang,Zhiyu Liang,Feng Chen,Danhua Xie,Yanling Wu,Xuxu Wang,Guiyang Yan,Ling Wu
Magnetically recyclable porous sodium dodecyl sulfate (SDS)/Fe 2 O 3 hybrids, which combine the porous structure of Fe 2 O 3 and hydrophobicity of SDS, have been successfully synthesized for the first time. Porous Fe 2 O 3 has been first pyrolyzed from MIL-100(Fe) using a simple two-step calcination route. Then, the obtained porous Fe 2 O 3 nanoparticles have been self-assembled with SDS molecules and yielded hydrophobic SDS/Fe 2 O 3 hybrids. The porous SDS/Fe 2 O 3 hybrids have been demonstrated to be highly efficient for the denitrification of pyridine under visible light irradiation. The pyridine removal ratio has reached values as high as 100% after irradiation for 240 min. Combining the results of a series of experimental measurements, it was concluded that the superior photocatalytic performance of SDS/Fe 2 O 3 hybrids could be attributed to (i) the fast electron transport owing to the unique porous structure of Fe 2 O 3 , (ii) the superior visible light absorption of Fe 2 O 3 nanoparticles, and (iii) the “bridge molecule” role of SDS efficiently improving the separation and transfer across the interfacial domain of SDS/Fe 2 O 3 of photogenerated electron-hole pairs. More significantly, after the catalytic reaction , the SDS/Fe 2 O 3 hybrids could be easily recovered using magnets and reused during subsequent cycles, which indicated their stability and recyclability.
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高影响因子
Chinese Journal of Natural Medicines
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2019
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IF 1.773
Yan YAN,Qiang LI,Hui-Zhi DU,Chen-Xi SHEN,Ai-Ping LI,Xiang-Ping PEI,Chen-Hui DU,Xue-Mei QIN
ABSTRACT Ziziphi Spinosae Semen (ZSS) has been used for treatment of insomnia in China for centuries. To reveal the influence of insomnia on the levels of the neurotransmitters including serotonin (5-HT), glutamic acid (Glu), γ -aminobutyric acid (GABA), noradrenaline (NE) and dopamine (DA), and to study the role of ZSS aqueous extract in the treatment of insomnia, an UPLC-ESI- MS/MS method was developed and validated for simultaneous determination of five neurotransmitters in the rat brain. The brain samples were pretreated by one-step direct protein precipitation with acetonitrile. The analytes were detected in positive mode with multiple reaction monitoring (MRM) and the procedure was completed in less than 10 min. The method showed a good linearity ( R 2 > 0.9967) with the other validation parameters were within acceptance range. The results indicated that the concentration of 5-HT, GABA and DA is significantly lower ( P < 0.01) in para -chlorophenylalanine (PCPA)-induced insomnia rat model group, while Glu and NE significantly higher than those in control group ( P < 0.01). Treatment with ZSS aqueous extract (4 or 8 g·kg –1 ·d –1 for seven days) could ameliorate the symptoms of insomnia by significantly changing the levels of the neurotransmitter parameters mentioned above. The data obtained in this study demonstrate that ZSS aqueous extract could ameliorate the symptoms of insomnia by modulating the levels of monoamines and amino acid neurotransmitters in the brain.
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PubMed
高影响因子
CHINESE JOURNAL OF CATALYSIS
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2019
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IF 4.914
Lijie Xu,Lanyue Qi,Yang Sun,Han Gong,Yiliang Chen,Chun Pei,Lu Gan
Excitation of metal-free graphitic carbon nitride (g-C 3 N 4 ) under visible light can successfully achieve efficient activation of peroxymonosulfate (PMS). Synergistic effects and involved mechanism were systematically investigated using a light-inert endocrine disrupting compound, dimethyl phthalate (DMP), as the target pollutant. Under visible light irradiation, DMP could not be degraded by direct g-C 3 N 4 -mediated photocatalysis , while in the presence of PMS, the dominant radicals were converted from •O 2 to SO 4 • - and •OH, resulting in effective DMP degradation and mineralization. Results showed that higher dosage of PMS or g-C 3 N 4 could increase the activation amount of PMS and corresponding DMP degradation efficiency, but the latter approach was more productive in terms of making the most of PMS. High DMP concentration hindered effective contact between PMS and g-C 3 N 4 , but could provide efficient use of PMS. Higher DMP degradation efficiency was achieved at pH lower than the point of zero charge (5.4). Based on intermediates identification, the DMP degradation was found mainly through radical attack (•OH and SO 4 • - ) of the benzene ring and oxidation of the aliphatic chains.
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高影响因子
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
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2019
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IF 2.338
Wen-qiang HUANG,Gui-hua LIU,Jin-bin JU,Xiao-bin LI,Qiu-sheng ZHOU,Tian-gui QI,Zhi-hong PENG
Effect of lithium ion in sodium aluminate solution on precipitation rate, lithium content, morphology, and crystallization of alumina trihydrate (ATH) was investigated. Results showed that increasing lithium ion concentration in solution improved the precipitation rate and lithium content in ATH, whereas reduced the mass fraction of lithium precipitation from solution. Lithium ion in solution generated the fine ATH, and thereafter significantly increased the total particle number due to the preferential nucleation. Elevating temperature or reducing lithium ion concentration decreased lithium content in ATH and reduced the fine particle amount. Moreover, lithium ion in the solution changed the morphology of ATH by improving the growth of the (110) and (200) planes of gibbsite. A large amount of fine bar- or flake-shaped ATH attached on the coarse particles also benefited the secondary nucleation and led to the poor strength of alumina. All results will further contribute to improving the quality of alumina.
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高影响因子
CHINESE JOURNAL OF CATALYSIS
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2018
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IF 3.525
Yanyan Guo,Chengna Dai,Zhigang Lei
We studied the hydrogenation of 2-ethylanthraquinone (eAQ) over Pd/SiO 2 /COR (COR = cordierite) monometallic and Pd-M/SiO 2 /COR (M = Ni, Fe, Mn, and Cu) bimetallic monolithic catalysts, which were prepared by the co-impregnation method. Detailed investigations showed that the particle sizes and structures of the Pd-M (M = Ni, Fe, Mn, and Cu) bimetallic monolithic catalysts were greatly affected by the second metal M and the mass ratio of Pd to the second metal M. By virtue of the small particle size and the strong interaction between Pd and Ni of Pd-Ni alloy, Pd-Ni bimetallic monolithic catalysts with the mass ratio of Pd/Ni = 2 achieved the highest H 2 O 2 yield (7.5 g/L) and selectivity (95.3%). Moreover, density functional theory calculations were performed for eAQ adsorption to gain a better mechanistic understanding of the molecule-surface interactions between eAQ and the Pd(1 1 1) or PdM(1 1 1) (M = Ni, Fe, Mn, and Cu) surfaces. It was found that the high activity of the bimetallic Pd-Ni catalyst was a result of strong chemisorption between Pd 3 Ni 1 (1 1 1) and the carbonyl group of eAQ.
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高影响因子
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