JOURNAL OF MEMBRANE SCIENCE
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2016
·
IF 5.557
Yupeng He,Zhi Wang,Songlin Dong,Song Zhao,Zhihua Qiao,Xiaochang Cao,Jixiao Wang,Shichang Wang
Improvement of the performance of CO 2 separation membrane under high temperature is of great importance in industrial applications. In this work, 2-aminoterephthalic acid (AA) was used to chemically cross-link polyvinylamine (PVAm) to fabricate PVAm-AA aqueous solution. PVAm-AA/polysulfone(PSf) composite membrane was then prepared by coating PVAm-AA aqueous solution on PSf support membrane. Through the chemical cross-linking by AA, the polymer chain mobility was restrained, resulting in the enhancement of thermal stability. The introduction of AA also increased the effective carrier content for CO 2 separation. Therefore, CO 2 permeance and CO 2 /gas selectivity of PVAm-AA/PSf membrane under relatively high temperature were greatly improved. For CO 2 /N 2 mixed gas (15/85 by volume), PVAm-AA/PSf membrane showed a CO 2 permeance of 661 Gas Permeation Unit (GPU) and CO 2 /N 2 selectivity of 95 at 0.3 MPa and 120 °C. Excellent performance stability was shown during the operation for 250 h at 120 °C. Moreover, PVAm-AA/PSf membrane displayed excellent separation performance and thermal stability for the separation of CO 2 /CH 4 and CO 2 /H 2 mixed gases.
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PROGRESS IN ORGANIC COATINGS
·
2016
·
IF 2.632
Jiahui Su,Xiaoxuan Liu,Chengjing Xiong,Hong Huang,Yanyan Cui
In this study, we prepared a novel triblock copolymer, PDMS- b -(PMAEBB- co -PDMAEMA) 2 ( tri -PI) bearing side-chain benzophenone (BP) and coinitiator amine, as a macro-photoinitiator via reversible addition-fragmentation chain transfer (RAFT) copolymerization of the polymerizable photoinitiator 2-(methacryloyloxy)ethyl-2-benzoylbenzoate (MAEBB) and the unsaturated coinitiator amine 2-(dimethylamino)ethyl methacrylate (DMAEMA) with a bifunctional polydimethylsiloxane (PDMS) macro-chain transfer agent (macro-CTA). The structure of synthesized copolymer was confirmed by Fourier-transform infrared spectroscopy (FT-IR), proton nuclear magnetic resonance ( 1 H NMR), differential scanning calorimetry (DSC), and gel permeation chromatography (GPC). The effects of the photoinitiator/coinitiator ratio, concentration, and photoinitiator systems on the photopolymerization kinetics of tri(propylene glycol) diacrylate (TPGDA) were investigated by real-time FT-IR. The mobility of the tri -PI chain segments was proven by X-ray photoelectron spectroscopy (XPS), and the surface morphology of TPGDA curing coatings was studied by scanning electron microscopy (SEM). Results showed that tri-PI strongly suppressed the effect of oxygen inhibition on the photopolymerization system. Tri-PI was also used in the curing of UV-curable waterborne polyurethane acrylate (UV-WPUA) resin to determine its versatility.
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MICROPOROUS AND MESOPOROUS MATERIALS
·
2017
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IF 3.615
Yajun Du,Lingping Cheng,Long Chen,Yunchao He,Yaling Wu,Shanshan He,Yanxiong Ke
Sub-2 μm large-pore monodispersed mesoporous silica spheres (MMSS) were synthesized by using mixed non-ionic surfactants of dodecylamine (DDA) and dodecylamine polyoxyethylene ether (AC1210) as templates through an alkali-catalyzed silica sol–gel technique combined with the template method. Methanol-H 2 O volume ratio on morphology was researched in detail. In addition, by using hydrothermal treatment , the average pore size of MMSS could be enlarged to 11 nm from 4.4 nm. The mesoporous silica particles were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), laser particle size analyzer, X-ray diffraction, N 2 physisorption technique. The synthesized sub-2 μm monodispersed mesoporous silica microspheres were successfully functionalized by dimethyloctadecylchlorosilane and used as a packing material in high performance liquid chromatography (HPLC).
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2016
·Vol. 408
·期 25
·7067-7075
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IF 3.125
Dang Qian,Gao Hongfang,Li Zhejian,Qi Honglan,Gao Qiang,Zhang Chengxiao
A simple and sensitive electrogenerated chemiluminescence biosensor was developed to monitor matrix metalloproteinase 2 (MMP-2) by employing a specific peptide (CGPLGVRGK) as a molecular recognition substrate. Bis(2,2′-bipyridine)-4′-methyl-4-carboxybipyridine-ruthenium N -succinimidyl ester-bis(hexafluorophosphate) (Ru(bpy) 2 (mcbpy-O-Su-ester)(PF 6 ) 2 (Ru1) was used as ECL-emitting species and covalently labeled onto the peptide through NH 2 -containing lysine on the peptide via acylation reaction to form Ru1-peptide as an ECL probe. An ECL peptide-based biosensor was fabricated by self-assembling the ECL probe onto the surface of gold electrode. MMP-2 can specifically cleave the Ru1-peptide on the electrode surface, which led the partly Ru1-peptide to leave the electrode surface and resulted in the decrease of the ECL intensity obtained from the resulted electrode in 0.1 M phosphate-buffered saline (pH 7.4) containing tri- n -propylamine. The decreased ECL intensity was piecewise linear to the concentration of MMP-2 in the range from 1 to 500 ng/mL. Moreover, the ECL biosensor is successfully applied to detection of MMP-2 secreted by living cell, such as HeLa cells. Additionally, the biosensor was also applied to the evaluation of matrix metalloproteinase inhibitors. The strategy presented here is promising for other disease-related matrix metalloproteinase assay and matrix metalloproteinase inhibitor profiling with sensitivity and simplicity.
Detection of MMP-2 released from living cells by ECL peptide-based biosensor
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JOURNAL OF CHEMICAL THERMODYNAMICS
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2016
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IF 2.196
Cui Wang,Yao Chen,Kai Cheng,Caiyu Wen
(Liquid + liquid) equilibrium (LLE) for the ternary systems of {water + acetone + diethyl carbonate (DEC)} and (water + 2-butanone + DEC) were determined at T = (293.15, 298.15, 303.15, 313.15) K and p = 100 kPa. The reliability of the experimental LLE was verified by the Othmer-Tobias and Bachman equations. The experimental LLE values were correlated with the modified and extended UNIQUAC models. Distribution coefficients and separation factors were calculated from the LLE data to evaluate the extraction capability of the organic solvents.
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OPTIK
·
2016
·
IF 0.742
Renping Cao,Dedong Peng,Haidong Xu,Zhiyang Luo,Hui Ao,Siling Guo,Jingwei Fu
Sr 3 (VO 4 ) 2 :Eu 3+ and Sr 3 (VO 4 ) 2 :Eu 3+ , Li + phosphors are synthesized by solid-state reaction method in air. X-ray diffraction patterns indicate that all samples are pure phase Sr 3 (VO 4 ) 2 . The host Sr 3 (VO 4 ) 2 with excitation 348 nm emits yellow-green light. Emission spectrum of Sr 3 (VO 4 ) 2 :Eu 3+ phosphor with excitation 335 nm contains a broad emission band peaking at ∼540 nm due to V 5+ → O 2− charge transfer and some narrow emission bands owing to the 4 f – 4 f electron transations of Eu 3+ ion in the range of 400–780 nm. With excitation 394 nm, only emision bands derived from Eu 3+ ion are observed. Emission intensity of Sr 3 (VO 4 ) 2 :Eu 3+ phosphor can be improved obviously due to charge compensation and fluxing agent role of Li + ion when Li + ion is co-doped. The optimal Eu 3+ doping concentration is ∼5 mol%. The energy transfer process between [VO 4 ] 3− group and Eu 3+ ion is observed and analyzed by emission spectrum in Sr 3 (VO 4 ) 2 :Eu 3+ phosphor. The luminous mechanism of Sr 3 (VO 4 ) 2 :Eu 3+ phosphor is explained by energy transfer and energy level diagram of [VO 4 ] 3− group and Eu 3+ ion.
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RSC Advances
·
2016
·Vol. 6
·期 18
·15210-15219
·
IF 3.289
Zhi Cheng,Shi Mo,Jing Jia,Ji Feng,Hong Qun Luo,Nian Bing Li
The inhibition effect of 4,6-diamino-2-mercaptopyrimidine (DAMP) as a copper corrosion inhibitor in 3.5 wt% NaCl solution was investigated by weight loss, electrochemical impedance spectroscopy, and potentiodynamic polarization. The inhibition efficiency increased with increasing DAMP concentration in the range of 1.0 to 2.0 mM DAMP and decreased with increasing temperature. The obtained results showed that DAMP inhibited both the anodic and cathodic currents and the maximum inhibition efficiency reached 93.2% at 2.0 mM DAMP. The inhibition performance of DAMP was confirmed by SEM and EDS. Quantum chemical calculations revealed that the DAMP molecule was adsorbed on the copper surface in a paralleled way through S and N atoms and the pyrimidine ring. Adsorption of DAMP was found to obey the Langmuir adsorption isotherm.
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APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2015
·Vol. 178
·期 8
·1471-1480
·
IF 1.735
Zheng Jian-yong,Liu Yin-yan,Luo Wei-feng,Zheng Ren-chao,Ying Xiang-xian,Wang Zhao
A new esterase-producing strain ( Bacillus cereus WZZ001) which exhibiting high hydrolytic activity and excellent enantioselectivity on rac -α-ethyl-2-oxo-pyrrolidineacetic acid methyl ester ( R , S - 1 ) has been isolated from soil sample by our laboratory. In this study, the stereoselective hydrolysis of ( R , S - 1 ) was performed using the recombinant Bacillus cereus esterase which expressed in Escherichia coli BL21 (DE3). Under the optimized conditions of pH 8.0, 35 °C, and concentration of substrate 400 mM, a successful enzymatic resolution was achieved with an e.e.
s of 99.5 % and conversion of 49 %. Immobilization considerably increased the reusability of the recombinant esterase; the immobilized enzyme showed excellent reusability during 6 cycles of repeated 2 h reactions at 35 °C. Thereby, it makes the recombinant B. cereus esterase a usable biocatalyst for industrial application.
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PubMed
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 107
·105723-105728
·
IF 3.289
Cheng Chen,Yan Li,Lijian Liu
Oligomers as fluorescent macromolecules are of significant importance and are fairly attractive for high quantum yield two-way conversion luminescence. We report a high conversion rate (ΦF = 0.5184) for a fluorescent oligomer, 1,4-butanediol-bis(5-carbonyl-3-carbethoxy-2-pyrazoline). It was prepared by the novel cyclopolycondensation of 1,4-butanediol-bis(5-carbonyl-3-carbethoxy-2-pyrazoline), a chromophore with good fluorescence (ΦF = 0.0573). After polymerization, a green fluorescent protein (GFP)-mimetic structure was formed, in which a methylene chain (–CH2–CH2–CH2–CH2–) as a flexible group is beneficial due to its folding, and an azo group sits in the rigid pyrazoline ring because of a resonance effect. These factors collectively contribute to the excellent efficiency of the fluorescence performance of the oligomer. Additionally, the oligomer exhibited a weak red shift and a significant fluorescence enhancement compared with the monomer, and we achieved good quality live-cell imaging. The oligomer also allowed for the enhancement of fluorescence intensity through the two-wavelength excitation of a cell rather than increasing the dosage of the dye or the power of the laser.
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ELECTROCHIMICA ACTA
·
2016
·
IF 4.803
Yonghao Zhang,Tingting Yu,Weiqing Han,Xiuyun Sun,Jiansheng Li,Jinyou Shen,Lianjun Wang
A novel tubular porous electrode electrocatalytic reactor was employed to undertake electrochemical treatment of actual anticancer drugs wastewater containing 5-Fluoro-2-Methoxypyrimidine. Effects of operating parameters on the performance of the reactor were studied with the discussion of energy consumption. The results indicated that the optimal condition was flow rate of 0.31 L min −1 , pH value of 5.0, current density of 5 mA cm −2 and without supporting electrolyte. In addition, the degradation intermediates and final products of 5-Fluoro-2-Methoxypyrimidine were analyzed by GC-MS and IC system. A pathway for the electrochemical degradation was proposed as well by quantum chemical calculation using DFT method. After treatment in the reactor, COD and 5-Fluoro-2-Methoxypyrimidine of the wastewater were removed by 84.1% and 100%. Particularly, the BOD 5 /COD value and EC 50,48h value of wastewater were increased from 0.14 and 16.4% to 0.53 and 51.2% respectively, indicating a great biodegradability enhancement. Besides, the electric energy consumption and operating cost of the reactor were only 1.5 kWh kg −1 COD and $ 0.78 per ton, lower than the other conventional electrochemical reactors. The excellent performance as well as the low energy consumption of the electrocatalytic reactor confirmed that electrochemical oxidation is highly applicable for the treatment of anticancer drugs wastewater.
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CANCER LETTERS
·
2017
·
IF 6.375
Changzheng Wang,Hongwei Lv,Wen Yang,Ting Li,Tian Fang,Guishuai Lv,Qin Han,Liwei Dong,Tianyi Jiang,Beige Jiang,Guangshun Yang,Hongyang Wang
Cholangiocarcinoma (CC) is a devastating malignancy with late diagnosis and poor response to conventional chemotherapy. Recent studies have revealed anti-cancer effect of vitamin C ( l -ascorbic acid, ascorbate) in several types of cancer. However, the effect of l -ascorbic acid (AA) in CC remains elusive. Herein, we demonstrated that AA induced cytotoxicity in CC cells by generating intracellular reactive oxygen species (ROS), and subsequently DNA damage, ATP depletion, mTOR pathway inhibition. Moreover, AA worked synergistically with chemotherapeutic agent cisplatin to impair CC cells growth both in vitro and in vivo. Intriguingly, sodium-dependent vitamin C transporter 2 (SVCT-2) expression was inversely correlated with IC50 values of AA. Knockdown of SVCT-2 dramatically alleviated DNA damage, ATP depletion, and inhibition of mTOR pathway induced by AA. Furthermore, SVCT-2 knockdown endowed CC cells with the resistance to AA treatment. Finally, the inhibitory effects of AA were further confirmed in patient-derived CC xenograft models. Thus, our results unravel therapeutic potential of AA alone or in combination with cisplatin for CC. SVCT2 expression level may serve as a positive outcome predictor for AA treatment in CC.
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JOURNAL OF MEMBRANE SCIENCE
·
2017
·
IF 6.035
Xuehua Ruan,Xinfang Zhang,Xuhang Liao,Xiaobin Jiang,Yan Dai,Xiaoming Yan,Gaohong He
Zeolitic imidazolate framework-8 (ZIF-8) with regular pore size (~ 0.34 nm) is widely attempted for gas separation membranes based on size sieving. However, the prospect is subjected to fabricating the continuous ZIF-8 membranes with high mechanical stability and uniformity. In response, an adhesive layer of Zn(II)-doped polydopamine (Zn-PDA) is pre-coated on the stainless steel nets in this work to improve ZIF-8 nucleation and growth. Zn-PDA layer shows high tolerance to ultrasonic agitation and heated methanol (system for ZIF-8 synthesis), little dissolution within 24 h, which supplies a high stable surface for ZIF-8 growth. Furthermore, the Zn(II) doped in PDA layer is opportunely serving as the even-distributed ZIF-8 nucleation starting sites, verified with the EDX and FE-SEM images for the aggregated Zn(II) clusters and the nascent ZIF-8 crystals. Therefore, an indented and hinged boundary is constructed between ZIF-8 and substrate to enhance the mechanical stability. The FE-SEM images after ultrasonic agitation show that the continuous ZIF-8 membranes prepared on Zn-PDA layers can tolerate the deformation to a certain extent. Finally, the prepared ZIF-8 membranes behave excellently with α H2/CO2 = 9.9, α H2/CO = 17.2, α H2/CH4 = 26.0, and permeation rate J H2 = 3980 GPU. This work supplied a useful approach to enhance mechanical stability and uniformity of defect-free ZIF-8 membranes.
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