Journal of Environmental Chemical Engineering
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2025
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IF 7.2
Yimu Qiao,Xue Han,Yijia Ren,Feiyong Chen,Cuizhen Sun,Jin Wang,Zhigang Yang,Linxu Xu,Xue Shen,Rupeng Liu
The extensive use of ibuprofen (IBU) and acetaminophen (APAP) has led to their accumulation in surface water, resulting in combined pollution with natural organic matter (NOM). In this study, a novel modified chitosan-based coagulant (CTS-DMDAAC) was successfully synthesized by adding ceric ammonium nitrate (CAN) to make chitosan (CTS) and dimethyldiallylammonium chloride (DMDAAC) produce free radicals for graft copolymerization. The study investigated the effects of pH, initial NOM concentration, and suspended particulates on the performance of contaminant removal and the characteristics of flocs. Through analysis of the Zeta potential and floc characteristics, the primary flocculation mechanisms were identified as: net capture and sweep, charge neutralization, and bridging effect. CTS-DMDAAC demonstrated effective removal of NOM, particularly humus, but encountered challenges in removing small-molecule pharmaceuticals such as IBU and APAP, with removal rates below 15%. To enhance the removal rate of small organic molecules, powdered activated carbon (PAC) was incorporated into the coagulation system, resulting in increased removal rates of IBU and APAP to 71.44% and 79.9%, respectively. Additionally, PAC improved the bridging capacity during coagulation, resulting in a 1.25-fold increase in the strength factor and a 2.34-fold increase in the recovery factor of the flocs. These findings suggest that the combined use of PAC and CTS-DMDAAC presents a novel approach for treating water bodies contaminated with NOM and pharmaceutical complexes.
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Materials Research Express
·
2024
·Vol. 11
·期 11
·115308
·
IF 1.8
Yang Gao,Huanjun La,Haonan Min,Zhenzhong Hou
Hydrogels have demonstrated significant potential in wound dressings, owing to their adjustable water content, excellent biocompatibility, and other advantages. An ideal wound dressing requires absorbing exudate while maintaining mechanical properties to prevent secondary damage to the wound under external pressure. In this study, Polyacrylic Acid (PAA)/Chitosan (CS) double network hydrogels were prepared via radical polymerization, and the swelling ratio, compressive modulus, and other parameters were experimentally measured. A hyperelastic finite element model of the hydrogel was then established, and its rationality was validated by experiments. Based on the model, the impacts of CS content and dynamic water content on the compressive properties of PAA/CS hydrogels were analyzed. Tetracycline hydrochloride was loaded into PAA/CS hydrogels, the drug release performance and adhesion experiments were carried out. The results indicated that, compared with the hydrogels with 2.5% and 5% CS content, the hydrogel with 1% CS content had the highest swelling ratio, which was 1774%. Meanwhile, its equilibrium water content could attain 94.6%. When the water content varied within the range from 45% to 75%, the compressive strength of the hydrogel with 5% CS content ranged from 0.33 MPa to 1.22 MPa, similar to that of skin tissue. Additionally, the prepared drug-loaded PAA/CS hydrogels exhibited a drug release pattern approximately following the Korsmeyer-Peppas model within 7 days. They also exhibited remarkable adhesion to porcine skin and different substrate surfaces. This study provides a basis for the clinical application of PAA/CS double network hydrogels as wound dressings in the repair of infected wounds.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Huayong Luo,Juexi Zeng,Mingqi Xu,Qiongfang Tang,Tao Liu,Shuhan Wu,Shiyin Li,Hongwei Rong
The development of a sustainable and eco-friendly silver-based hybrid nanocomposite for safe and efficient point-of-use (POU) water disinfection remains a challenge. Herein, a simple and facile approach was proposed for the in situ immobilization of silver nanoparticles (AgNPs) on chitosan-g-poly (sulfobetaine methacrylate) (CS-g-PSBMA) hydrogel beads, which have been achieved via graft copolymerization of sulfobetaine methacrylate along the chitosan chains followed by a drop method. The AgNPs-decorated CS-g-PSBMA hydrogel beads were characterized and their bactericidal efficacy towards Escherichia coli was evaluated concurrently with their anti-biofouling behaviors. The results indicated that the grafted PSBMA hydrogels on CS would not only enhance the immobilization of more AgNPs (122.63 mg/g material), but also restricted the silver release (only 0.015 % after the 14th day of incubation), which surpassed numerous other AgNPs-based nanocomposites for water disinfection. Moreover, the release of silver can be modulated by altering the temperature due to the thermosensitivity of PSBMA, and the maximum concentration of silver leaching in the effluent was 33.1–52.3 μg/L at 25–60 °C. Importantly, the synthesized AgNPs-based CS-g-PSBMA can exert both exceptional bactericidal and superior anti-biofouling capabilities as well as reusability features, indicating sustained antibacterial effectiveness and significant potential for practical applications in water disinfection.
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COMPOSITES COMMUNICATIONS
·
2025
·
IF 7.7
Yanwen Xiao,Qiaoyu Huang,Yong Hu,Yige Chen,Man Zhou,Zhaoxia Chen,Xueliang Jiang,Yuhong Zhang
Creating conductive hydrogel flexible wearable sensors with excellent conductivity, adhesion, antibacterial and biocompatibility still poses a challenge. Herein, an electrically stable multifunctional poly (vinyl alcohol)/quaternary ammonium chitosan-lithium ion conducting hydrogel (PVA/HACC-Li + ) was fabricated. PVA-based hydrogels regulated by Li + and HACC have high electrical conductivity (12.35 ms/cm), high stretchability (∼372 %), excellent antibacterial properties, effectively inhibiting both Escherichia coli and Staphylococcus aureus, and very good biocompatibility (L929 cell survival rate of 108.76 %). Moreover, PVA/HACC-Li + hydrogel successfully serve as strain sensor, which can accurately identify different joint and subtle muscle movements signals of the human body with high sensitivity (GF = 2.42), wide sensing range (0–300 %) and fast response time (183 ms). Thus, this endeavor offers a feasible method for utilizing versatile multifunctional hydrogels in the field of motion monitoring and serves a practical reference for the diverse applications within wearable electronic skin.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Junze Tang,Xin Cheng,Rui Pan,Jinfeng Li,Ziqiao Li,Wanting Liang,Hongshan Xie,Hailiang Zhang,Ji Zhao,Kun Yu,Xiaoyu Zhao,Xiaofei Li,Xujie Liu,Yan He
Wound healing presents a persistent challenge, particularly in enhancing tissue regeneration and mitigating inflammation. Conventional wound dressings often fall short in providing adequate protection against microbial infections and do not fully support the regenerative processes necessary for effective healing. In this study, extracellular vesicles (PPEVs) were successfully isolated from Paris polyphylla var. yunnanensis , with an average particle size of 156.8 ± 13.15 nm and a zeta potential of −15 ± 2.54 mV. Transmission electron microscopy (TEM) images confirmed that the PPEVs exhibited an irregular spherical shape, characteristics of extracellular vesicles. PPEVs demonstrated significant anti-inflammatory properties, reducing the expression of pro-inflammatory cytokines, including IL-1β, IL-6, and TNF-α by >1.5 times relative to the model group. Additionally, PPEVs promoted the expression of epidermal growth factor and collagen mRNA, exhibiting potent reactive oxygen species (ROS) scavenging activity, with 50 % reduction in ROS levels in the high-concentration group compared to the positive control. To facilitate the controlled delivery of PPEVs and promote wound healing, a composite hydrogel was developed by incorporating polyvinylpyrrolidone (PVP) and carboxymethyl chitosan (CMC) through physical crosslinking. The hydrogel exhibited high porosity (43.6 ± 7.2 %) and remarkable swelling capacity (445.4 ± 38.3 %), with a drug release of 61.3 ± 11.8 % within 6 h. Rheological analysis revealed that the hydrogel exhibited pseudoplastic behavior and elastic characteristics, with good thermal stability. In vivo studies demonstrated that the wound healing rate in the PPEVs@PVP/CMC hydrogel group on day 7 (82.17 ± 5.44 %) was significantly higher than that of the control group (58.5 ± 12.15 %). On day 14, the wounds in the PPEVs@PVP/CMC group were nearly completely healed, with a healing rate of 99.66 ± 0.42 %, significantly surpassing the control group (95.85 ± 0.90 %). Therefore, the PPEVs@PVP/CMC hydrogel can serve as a safe and efficient wound dressing to regulate the inflammatory response and accelerate wound healing in mice. This finding suggests that utilizing the PPEVs@PVP/CMC hydrogel may be a promising strategy for wound healing.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
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IF 3.8
Li Ma,Yilong Yao,Xiong Zhao,Junsheng Hou,Lei huang,Zihan Ding,Xinlan Lu,Jinjia Wei,Nanjing Hao
The uniformity and monodispersity of the chitosan microsphere are essential requirements for its related applications, and the appearance of undesired satellite droplets needs to be avoided. However, preparing monodispersed, uniform, and size-controllable chitosan microspheres is still a significant challenge. In this paper, a droplet-based microfluidic strategy is developed for the chitosan and fluorescent chitosan microsphere synthesis with controllable size and monodispersity. A water-in-oil droplet microfluidic reaction system is formed, and the monodispersed viscous droplet generation one by one in a step T-junction microchannel and solidified microspheres is observed via a chemical cross-reaction. A side microchannel is designed to separate satellite droplets successfully and improve the quality of the product. The effects of flow rates of two phases, phase ratio, and reaction time are investigated experimentally. The stable operating range for viscous droplets is given. The size of the chitosan could be tuned from 50 to 200 μm, and the production rate could reach up to 1.2 mL·h–1. This work not only provides valuable guidance for polymer microsphere synthesis but also helps to understand the microdispersion mechanism of the non-Newton viscous fluid in depth.
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Polymer Chemistry
·
2024
·
IF 4.1
Ningning Zhang,Xianjie Pan,Aoqian Xi,Wenpei Chen,Ting Huang,Yanning Zeng
The increase in nondegradable polymer waste and the depletion of nonrenewable fossil resources result in environmental concerns and unsustainable industrial development. It is significant to fabricate polymer thermosets with degradable, self-healable, weldable and recyclable performances from biomass. Herein, for the first time, natural peach gum (PG) as an attractive feedstock was employed to prepare degraded and recycled polyimine (PI) networks, due to the hydrolysable and renewable nature of PG. Firstly a peach gum polysaccharide with pendent –CHO groups (PGP-CHO) was synthesized through a graft reaction between 4-formylbenzoic acid and PGP; then it was cured with chitosan (CS) via a moderate and catalyst-free Schiff base reaction resulting in fully biobased PI networks (PGCS). The resultant PGCS-100 networks display good mechanical properties (tensile strength of ∼56.5 MPa and Young's modulus of ∼439 MPa) and high thermal stability (initial decomposition temperature around 227.1 °C). Meanwhile, the PGCS-100 network containing the most dynamic imine bonds exhibits superior self-healing, welding, shape memory and reprocessing performances. Moreover, PGCS-100 can be degraded completely under acidic conditions, allowing sustainable recycling. Furthermore, PGCS-100 can be applied in recycled adhesion, exhibiting excellent adhesion strength (10.5 MPa). Briefly, a new strategy to develop green environmentally friendly PI networks with high performance from biomass is provided, contributing to the reduction of polymer waste and sustainable industrial development.
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POLYMER ENGINEERING AND SCIENCE
·
2024
·
IF 3.2
Yao Xiao,Yukun Zhou,Yinggang Huang,Biao Li,Yaqi Ge,Zhenchun Xu,Chuansheng Wang,Huiguang Bian
In this paper, chitosan (CS), which is naturally degradable and low-cost, was incorporated into nitrile butadiene rubber (NBR), the effects of chitosan amount on the properties of the NBR composites were investigated, and the optimal amount of chitosan was determined. On this basis, CS, silica and Si69 were modified by ball milling and plasma to prepare NBR composites with higher oil resistance and high temperature resistance. The results showed that the overall properties of NBR composites filled with 2phr CS is better. FTIR and SEM demonstrated the surface polarity of ball milling combined with plasma co-modified CS/silica was weakened, the dispersion of fillers in the NBR matrix was promoted, the oil resistance and high-temperature resistance of the composites were enhanced, the cross-linking density and tear strength were improved by 28.12%, and 51.76% compared with that of the NBR composites without CS. The investigation on the oil and high-temperature resistance of NBR composites for blowout preventer cores has been carried out, which promotes the development of blowout preventer cores toward high safety, low cost, and sustainability. Highlights The effect of chitosan amount on nitrile butadiene rubber (NBR) composites was explored. Chitosan, silica, and coupling agent were modified by ball milling and plasma. The oil and high-temperature resistance of NBR composites were improved. The tear strength was increased by 28% under double destructive environment.
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COMPOSITES PART B-ENGINEERING
·
2024
·
IF 12.7
Hang Zhang,Longhai Yi,Yezhou Ni,Zhenhua Jia,Hua Qiu,Kunlin Chen
Flexible conductive coatings have the potential to imbue traditional textiles with a range of functional or intelligent properties, including sensing, light emission, heat generation, etc. However, these flexible coatings are prone to damage from external forces in real-world applications. This study focuses on developing a chemically modified flexible coating with MXene as a conductive ligand, aiming to strike the characteristics of mechanical, conductive, and self-healing harmoniously. The process involves synthesizing modified 4-vinyl benzaldehyde into polyurethane (VPU), which is then cross-linked with chitosan to enhance the self-healing efficiency. The conductive ligand, MXene, was modified with tannic acid to strengthen hydrogen bonding with the VPUs. The resulting self-healing waterborne polyurethane conductive coating exhibits an impressive self-healing efficiency of 96 %, along with a high tensile strength at a break of 5.58 MPa and an elongation at a break of 340 %. It also demonstrates antimicrobial effects against Escherichia coli and Staphylococcus aureus of up to 86.8 % and 90.1 %, respectively. Importantly, this study also explores the wearable applications of flexible electronic devices. They can detect pressures up to 100 kPa in a maximum sensitivity of 0.204 kPa −1 in the initial pressure range from 1 to 15 kPa. They can also monitor the pressure response of the foot in different motion states, suggesting potential integration with insoles or socks. This work offers a practical method for combining the key properties of polymer conductive coatings with the design of carbon nanomaterial-based stress-strain sensors. They are potentially applied to this approach including smart robots, e-skins, wearable health management systems, and artificial intelligence, among others.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Xinyue Cao,Zaimei Li,Che Han,Conglu Zhang
Pharmaceuticals and personal care products and dyes have low biodegradability and high toxicity, seriously threaten the human health and ecological environment. Therefore, seeking effective removal methods has become the focus of research. In this study, silver-based metal-organic framework (Ag-MOF) and chitosan (CS) hybrid adsorbent (Ag-MOF-CS) was synthesized via solvothermal one-pot synthesis to remove diclofenac sodium (DCF) and acid Red 1 (AR1) from water for the first time. The morphology and structure of Ag-MOF-CS were confirmed by various characterizations. The effect on adsorption was investigated by changing the adsorbent dosage, pH and other conditions. The adsorption kinetics, adsorption isotherms and thermodynamics were analyzed. Ag-MOF-CS showed a high adsorption capacity. And the maximum adsorption capacity of Ag-MOF-CS for DCF and AR1 was 351.75 mg/g and 678.83 mg/g, respectively. The adsorbent bound to DCF and AR1 may via electrostatic forces, π-π interactions, hydrogen bonding. Even after four cycles of Ag-MOF-CS, the DCF removal can still be higher than 80 %. The eco-friendly Ag-MOF-CS demonstrated significant potential for utilization in treating wastewater.
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CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Tiantian Wang,Bingbing Xu,Tong Yu,Yan Yu,Jiayi Fu,Yuhang Wang,Xianwu Gao,Zhebin Xue,Ruoxin Li,Guangtao Chang
Hydrogels have garnered significant interest as promising materials for flexible wearable devices. However, it remains a major challenge to develop multifunctional hydrogels. In this study, we prepared a multifunctional hydrogel based on the polyvinyl alcohol (PVA) and chitosan (CS), which is characterized by high strength, good electrical conductivity, and resistance to freezing and water retention. The hydrogel formulation utilizes p -carboxyphenylboronic acid (PBA) and MXene in combination with freeze-thaw cycling and glycerin (GL) immersion technology. Additionally, we explored the applications of this hydrogel in motion detection and sensing. Research results indicate that the hydrogel has excellent mechanical properties, achieving a strength of up to 3.42 MPa, with modulus and toughness improved by 7 times and 5 times, respectively, compared to pure PVA hydrogels. Moreover, when the MXene dispersion is at 8 vol%, the conductivity is 163.15 mS/m, and we explore their applications in strain sensing (GF = 7.03) and motion detection. The hydrogels exhibit a good strain range (600 %) and a fast response time (42 ms), as well as regular and stable electrical signals demonstrated at joints and breathing, providing strategic support for the application of this hydrogel in the field of smart wearable flexibility.
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ChemistrySelect
·
2025
·Vol. 10
·期 35
·e01362
·
IF 2
Changshun Lv,Xiangru Feng,Boyuan Jian,Xue Jiang,Tianhui Liu,Leijiao Li,Qingshuang Wang
One of the main challenges in wound healing is bacterial infection, and the emergence of antibiotic resistant superbugs in recent years has exacerbated these concerns. In this study, we developed a chitosan/tannic acid/poloxamer 407/poloxamer 188 thermo-sensitive hydrogel (CTPP). The bioactive compound α-Mangostin (α-M) extracted from mangosteen fruit was incorporated into CTPP (CTPP@α-M). The results indicate that CTPP@α-M can slowly and continuously release α-M within 11.5 h. In addition, CTPP@α-M effectively inhibits bacterial proliferation, accelerates collagen deposition, reduces inflammatory response, and promotes rapid wound healing in the presence of wound infection. The biosafety experiment showed that the hydrogel had excellent biocompatibility. Overall, these findings suggest that CTPP@α-M has the potential to become a potential treatment for repairing infectious wounds. Graphical In this study, CTPP hydrogel and CTPP @ α - M drug carrying hydrogel were prepared by physical crosslinking method. CTPP shows excellent performance and can be converted to semi-solid gel at 37 ° C. CTPP @ α - M showed strong inhibitory effects on MRSA and accelerated wound healing, reducing the expression of pro-inflammatory cytokines. The data show that CTPP @ α - M is a highly effective antibacterial thermosensitive hydrogel with excellent performance.
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