查找使用阿拉丁产品的科研文献

Widely targeted metabolomics and physiological analyses reveal the impact of ‘Zhongmikangzhen No. 2’ rootstock on Actinidia deliciosa

Peng Zhang,Miaomiao Lin,Gloria De Mori,Congcong Li,Guido Cipriani,Sumei Li,Qina Zhang,Zhenzhen Zhang,Yihang Li,Leiming Sun,Jinbao Fang,Xiujuan Qi

Kiwifruit has extremely high nutritional value, but its rootstock strongly influences the physiology and metabolism of its scion fruit. Here, we evaluated the influence of a new kiwifruit rootstock, Actinidia valvata ′Zhongmikangzhen No. 2′, on the leaves and fruits of the scion A. deliciosa ′Zhongmi 2′. The leaf size, leaf mineral element contents, fruit size (single-fruit weight, longitudinal diameter and transverse diameter), and fruit quality traits (soluble sugar content, vitamin C content, total acidity and dry matter content) of ′Zhongmi 2′ grafted on ′Zhongmikangzhen No. 2′ (zk) and A. deliciosa seedling (zp) rootstock were measured at five fruit developmental stages (30, 60, 90, 120, and 150 days after flowering (DAF)). The zk fruits were significantly larger than those of zp and their leaves were also longer. The leaf length and width of the zk fruits was significantly greater than those of the zp fruits. The leaf contents of Cu, P and Mo significantly differed at 60, 120 and 120 DAF, respectively. The fruits of the two stock–scion combinations may presented different flavors. UPLC–MS/MS analysis of the fruit metabolome revealed 1697 differentially expressed metabolites. These metabolites, which were divided into multiple categories through KEGG analysis, indicated significant differences in fruit quality and resistance. Decanoic acid (decreased in zk-hard) and 9-oxononanoic acid (increased in zk-hard) may collectively affect fruit aroma. Moreover, α-linolenic acid and 12-oxo-phytodienoic acid (a precursor of jasmonic acid), both of which increase in zk-hard, contribute to increased nutritional value and are involved in the abiotic stress response, respectively. This study revealed the effects of different rootstock–scion combinations on fruit quality traits and leaf mineral elements and provides a basis for studying the mechanisms of rootstock–scion interactions.

Influence of hexagonal boron nitride on the selective catalytic reduction of NO with NH3 over CuOX/TiO2

Dongsheng Zhou,Zhiyuan Ren,Bo Li,Zhaoxia Ma,Xiaobin Zhang,Hangsheng Yang

Hexagonal boron nitride (hBN) was used as a CuOX/TiO2 catalyst carrier and its effect on NO reduction with NH3 was studied. After hBN was treated with concentrated HNO3, CuOX/TiO2 nanoparticles were dispersed well onto hBN, and the addition of hBN was found to promote NO oxidation, while at the same time suppress NH3 oxidation to NO, and thus promoted the selective catalytic reduction of NO at reaction temperatures between 150 to 350 °C, and a high de-NOX efficiency of 90.6% was achieved at 275 °C. Our study indicates that hBN is a promising catalyst promoter and carrier with excellent stability compared to carbonaceous materials.

Ultrasound-Responsive Hydrogel with ROS Scavenging and NO Controllable Release Capabilities for Accelerated Healing of Diabetic Wounds

Jialei Luo,Xinyi Yan,Kang Fu,Yuxuan Qiu,Yana Xu,Zhaojie Wang,Xuexiao Li,Ting Lin,Ying Wang,Yunting Zhang,Yawei Yu,Shibo Wang,Jianqing Gao,Gaoyi Yang

Diabetic wounds represent a common and challenging complication of diabetes mellitus, characterized by a complex pathological microenvironment that includes excessive reactive oxygen species (ROS), chronic inflammation, hypoxia, and impaired nitric oxide (NO) synthesis. These factors collectively contribute to delayed wound healing, increased infection risk, and potential progression to chronic non-healing ulcers. Herein, we constructed a multifunctional injectable hydrogel (Prussian blue nanozyme and S-nitrosothiol-loaded hydrogel, PBE&SNO@HG) co-loaded with multi-enzyme-mimicking Prussian blue nanozymes (PBE) and an ultrasound-responsive nitric oxide (NO) donor (SNO). This composite hydrogel exhibited favorable injectability and tissue adhesiveness. The incorporated PBE nanozymes simultaneously mimicked superoxide dismutase (SOD) and catalase (CAT), enabling the scavenging of superoxide anions (⋅O 2 - ) and hydrogen peroxide (H 2 O 2 ), thereby reducing oxidative stress levels at the wound site. Additionally, the ultrasound (US)-responsive release of NO promoted angiogenesis and alleviates inflammatory responses in the wound area. Animal experiments demonstrated that this hydrogel system significantly enhances collagen deposition, accelerates re-epithelialization, promotes hair follicle regeneration, and accelerates wound healing. This study demonstrated the synergistic effect of combining antioxidant strategies with gas therapy in diabetic wound treatment, while also indicating that US-responsive hydrogel materials can achieve on-demand release of therapeutic molecules via external field stimulation, thereby providing a novel strategy for chronic wound management.

Spatiotemporal NO/O2-releasing cascade nanozyme microneedles enhance diabetic infected wound healing by modulating the immune microenvironment

Hanqing Zhao,Wenjun Shao,Man Jiang,Fangyuan Chen,Yingying Li,Xiaoyu Zhang,Tao Ma,Minglong Chen,Baohong Sun,Zekun Wang,Chuanbin Wu,Qingqing Wang

Rationale: Chronic diabetic wounds present significant therapeutic challenges due to biofilm resistance and dysregulated metabolism of glucose, reactive oxygen species (ROS), and nitric oxide (NO), which collectively exacerbate immunosuppression and impair tissue repair. Methods: This study developed a glucose-driven cascade nanozyme-loaded dissolvable microneedle system (PPLG@MN) that enables spatiotemporal regulation of the wound microenvironment through a closed-loop mechanism involving nutrient deprivation, gas modulation, and immune reprogramming. The system consists of porous Prussian blue nanozymes (PPB) loaded with glucose oxidase (GOx) and L-arginine (L-arg), which is precisely delivered into the tissue via microneedles. Results: PPLG@MN initiates a self-sustaining therapeutic cycle within the biofilm microenvironment, in which GOx catalyzes the oxidation of glucose to generate hydrogen peroxide (H 2 O 2 ), inducing bacterial starvation. Subsequently, H 2 O 2 reacts with PPB and L-arg to release oxygen (O 2 ) and biofilm-disrupting NO, thereby alleviating local hypoxia and enhancing antibacterial efficacy. Furthermore, the synergistic action of O 2 and NO reprograms macrophages toward an anti-inflammatory M2 phenotype (approximately 30-fold increase compared to the model group), effectively resolving inflammation and promoting angiogenesis. In vivo studies confirmed that the system achieved > 99.9% biofilm eradication efficiency and accelerated wound healing by 25.6% compared to the model group. Conclusion: This nanoplatform offers a clinically translatable therapeutic strategy for biofilm-associated diabetic wounds by synergistically combining gas therapy and immune reprogramming.

Simultaneously accomplishing selective catalytic reduction of NO and catalytic oxidation of CO in a catalyst coupling system

Xue Li,Xiaolong Liu,Hao Tang,Yang Zou,Wanglai Cen,Tingyu Zhu

Considering that nitrogen oxides (NO x ) and carbon monoxide (CO) usually meantime exist in industrial flue gas, it is meaningful to develop a collaborative control technology for the simultaneous purification of NO x and CO. In this work, the catalysts xCu-1V-5W/Ti were evaluated in the simultaneously selective catalytic reduction by NH 3 (NH 3 -SCR) and CO oxidation . The introduction of CuO provided the active sites for the oxidation of CO, while inhibited the NH 3 -SCR process and facilitated the generation of N 2 O by-product at high temperature. Accordingly, a catalyst coupling system was designed by employing 1V-5W/Ti and 2Cu-1V-5W/Ti catalysts in one reactor, and high NO conversion (>90 %) and CO removal efficiency (>80 %) could be simultaneously realized within 350–500 °C. This work would provide valuable insights for achieving simultaneous removal of NO x and CO using the catalyst coupling method.

Bacteria-Targeted Combined with Photothermal/NO Nanoparticles for the Treatment and Diagnosis of MRSA Infection In Vivo

Kai Lv,Guowei Li,Xiangjun Pan,Luxuan Liu,Ziheng Chen,Yu Zhang,Hao Xu,Dong Ma

Currently, undeveloped diagnosis and delayed treatment of bacteria-infected sites in vivo not only expand the risk of tissue infection but are also a major clinical cause of multiple drug-resistant bacterial infections. Here, an efficient nanoplatform for near-infrared (NIR)-light-controlled release and bacteria-targeted delivery of nitric oxide (NO) combined with photothermal therapy (PTT) is presented. Using maltotriose-decorated mesoporous polydopamine (MPDA-Mal) and BNN6, a smart antibacterial (B@MPDA-Mal) is developed to combine bacterial targeting, gas-controlled release, and PTT. Utilizing bacteria's unique maltodextrin transport system, B@MPDA-Mal can accurately distinguish bacterial infection from sterile inflammation and target the bacteria-infected sites for efficient drug enrichment. Moreover, NIR-light causes MPDA to generate heat, which not only effectively induces BNN6 to produce NO, but also raises the temperature to harm the bacteria further. NO/photothermal combination therapy effectively eliminates biofilm and drug-resistant bacteria. The myositis model of methicillin-resistant Staphylococcus aureus infection is established and indicates that B@MPDA-Mal can successfully eradicate inflammation and abscesses in mice. Meanwhile, magnetic resonance imaging technology is used to monitor the treatment procedure and healing outcomes. Given the aforementioned advantages, the smart antibacterial nanoplatform B@MPDA-Mal can be used as a potential therapeutic tool in the biomedical field against drug-resistant bacterial infections.

Green and facile synthesis of nanostructured Co3O4/CeO2 catalysts via a glucose-urea method for NO oxidation

Shengjun Yi,Pincai Lai,Guilin Ma,Jinjian Pan,Zhen Chen,Yuanhang Qin,Xingmao Jiang

Nanocatalysis plays an important role in chemical industrial production, environmental protection and etc. However, traditional catalyst preparation methods are generally labor-intensive, time-consuming and need high-temperature calcination, which are not conducive to the preparation of nanostructured catalyst. Therefore, developing a green and facile method for nano-sized catalyst preparation is very significative. In this work, a series of nano-sized Co 3 O 4 /CeO 2 catalysts with high specific surface area, high oxygen storage and homogeneous distribution of active species were synthesized via a glucose-urea (G-U method), and applied in NO oxidation The NO oxidation performance indicates that the 12.5% CoCe G−U catalyst prepared by the G-U method shows higher activity than those of catalysts prepared by the traditional methods (precipitation, hydrothermal and impregnation methods). The characterization results revealed that the CoCe G−U catalysts have the highest specific surface area, pore volume, content of surface Ce 3+ and Co 3+ among the catalysts. Moreover, the nano Co 3 O 4 is better dispersed on CeO 2 , which resulted in more active oxygen species on the surface of the catalysts prepared by the G-U method. Herein, the higher specific surface area, the smaller Co 3 O 4 nanoparticles, the more active oxygen species and the higher Ce 3+ and Co 3+ contents of the CoCe G−U catalyst lead to the more excellent NO oxidation performance. This work provides a green and efficient approach for the industrial production of nano-sized oxide catalysts.

Au Catalyzing Control Release NO in vivo and Tumor Growth-Inhibiting Effect in Chemo-Photothermal Combination Therapy

Ying Zhang,Tianfu Zhou,Jian Li,Nuo Xu,Mingze Cai,Hong Zhang,Qinfu Zhao,Siling Wang

One Step Synthesis of Oxygen Defective Bi@Ba2TiO4/BaBi4Ti4O15 Microsheet with Efficient Photocatalytic Activity for NO Removal

Ting Gao,Ke Zhang,Qiuhui Zhu,Qingyun Tian,Hui Wang,Wei Zhang,Jiangyushan Liang,Jingqi Lin,Ahmed A. Allam,Jamaan S. Ajarem,Peter K. J. Robertson,Chuanyi Wang

Photocatalysis is an effective technology for NO removal even at low concentrations in the ambient atmosphere. However, the low efficiency of this advanced process and the tendency of producing toxic byproducts hinder the practical application of photocatalysis. To overcome these problems, the Bi@Ba2TiO4/BaBi4Ti4O15photocatalytic composites were successfully prepared by a one-step hydrothermal method. The as-synthesized photocatalysts exhibited an efficient photocatalytic performance and generated low amounts of toxic byproducts. X-ray diffraction studies show that Bi3+is successfully reduced on the surface of Ba2TiO4/BaBi4Ti4O15(BT/BBT). After L-Ascorbic acid (AA) modification, the photocatalytic NO removal efficiency of Bi@Ba2TiO4/BaBi4Ti4O15is increased from 25.55% to 67.88%, while the production of the toxic byproductNO2is reduced by 92.02%, where the initial concentration of NO is diluted to ca. 800 ppb by the gas stream and the flow rate is controlled at 301.98 mL·min−1in a 150 mL cylindrical reactor. Furthermore, ambient humidity has little effect on the photocatalytic performance of theBi@Ba2TiO4/BaBi4Ti4O15, and the photocatalyst exhibits excellent reusability after repeated cleaning with deionized water. The improved photocatalytic effect is attributed to the addition of AA in BT/BBT being able to reduce Bi3+ions to form Bi nanoparticles giving surface plasmon effect (SPR) and generate oxygen vacancies (OVs) at the same time, thereby improving the separation efficiency of photogenerated carriers, enhancing the light absorption, and increasing the specific surface areas. The present work could provide new insights into the design of high-performance photocatalysts and their potential applications in air purification, especially for NO removal.Keywords:photocatalysis;BaBi4Ti4O15;surface plasmon effect;NO removal

Simultaneous NO/CO2 removal performance using Ce-doped CaO in calcium looping process: Experimental and DFT studies

Shoubing Chai,Yingjie Li,Wan Zhang,Zirui He

In carbonation stage of calcium looping process, NO could be reduced by CO using CaO as a catalyst, allowing simultaneous CO 2 and NO removal. However, to achieve efficient NO removal, the required CO/NO molar ratio in the carbonator is very high (up to 30:1), which leads to lots of unreacted CO in the exhaust gas. In this work, to maintain high efficiency of NO removal at low CO concentration in carbonator, Ce-doped CaO was employed to simultaneously enhance NO and CO 2 removal performance. The effects of Ce-doped CaO on simultaneous CO 2 and NO removal in bubbling fluidized bed reactor were investigated during the carbonation stage of calcium looping process. When the molar ratio of CO/NO is about 3.57:1, Ce-doped CaO obtains an 83% CO 2 capture efficiency and a 97% NO removal efficiency in 20 cycles in chemical reaction controlling stage. The average CO concentration in exhaust gas of Ce-CaO was reduced by 79% at the same NO removal efficiency as Mn-doped CaO. The presence of Ce 3+ makes the charge imbalance of the material, resulting in more charge transfer from the Ce-CaO surface to the molecules. The density functional theory reveals that Ce doping reduces the energy barriers of the conversion of NO to N 2 and the CO 2 adsorption, promoting the simultaneous NO/CO 2 removal in carbonation stage. Therefore, under a low molar ratio of CO/NO in carbonation stage of calcium looping, Ce considerably improves the simultaneous CO 2 and NO removal action of CO and CaO.

Efficient full spectrum responsive photocatalytic NO conversion at Bi2Ti2O7: Co-effect of plasmonic Bi and oxygen vacancies

Qiuhui Zhu,Reshalaiti Hailili,Yue Xin,Yingtang Zhou,Yu Huang,Xinzhu Pang,Ke Zhang,Peter K.J. Robertson,Detlef W. Bahnemann,Chuanyi Wang

Developing full-spectrum responsive and efficient photocatalysts is still an important challenge in the field of photocatalytic treatment of trace environmental pollutants. Herein, full-spectrum Bi@Bi 2 Ti 2 O 7 with rich-oxygen vacancies (OVs) were fabricated via a one-pot hydrothermal method. The optimized composite photocatalyst exhibited a photocatalytic efficiency of 79 %, more than doubled higher than that of its counterpart, Bi 2 Ti 2 O 7 (31.79 %), for removing ppb-level NO under visible-near infrared (Vis-NIR) irradiation. The enhanced photocatalytic performance was attributed to the co-effect of Bi and OVs reveal by control experiments and theoretical calculations, which not only benefited the adsorption and photocatalytic activation of NO but broadened light absorption to near infrared region. Furthermore, the adsorption and photocatalytic conversion pathway of NO was explored by in situ DRIFTS, suggesting that NO + as intermediate species is crucial to improve the selectivity of NO converting to nitrate. This work provides a new perspective of constructing full-spectrum-driven photocatalysts for environment remediation.

Experimental Study on the Removal of NO from Coal-Fired Flue Gas by the Na2SiO3/Fenton System

Shujun Sun,Jun Zhang,Changdong Sheng,Hui Zhong

A novel Na2SiO3/Fenton system was employed for NO removal from coal-fired flue gas in a bubble reactor. The NO removal efficiency of this system could reach 94.36% when the flue gas residence time was 3 s. The hydrolysis reaction of Na2SiO3 produced OH-, which made the solution alkaline, and the formation of iron-based colloids in the alkaline environment effectively catalyzed the generation of free radicals from H2O2, O2•– radicals, which was the main reason for the increase of NO removal efficiency. The reaction of H2O2 catalyzed by iron-based colloids increased the solution pH, which could not only further improve the NO removal efficiency but also enhance the useless decomposition of H2O2. Na2SiO3 could buffer the solution pH, which weakened the ineffective decomposition of H2O2 and prolonged the effective denitrification time. The X-ray diffraction and ion chromatography analysis showed that NO was finally converted to NO3– and NO2–.