JOURNAL OF CHROMATOGRAPHY A
·
2012
·
IF 4.531
Zian Lin,Hui Huang,Xiaobo Sun,Yao Lin,Lan Zhang,Guonan Chen
A new polymer monolith with three modes of reverse-phase, hydrophilic and cation-exchange interaction was synthesized in 100 μm i.d. fused-silica capillary by in situ polymerization procedure. The pre-polymerization mixture consisted of glycidyl methacrylate (GMA) and 4-vinylphenylboronic acid (VPBA) as bifunctional monomers, ethylene dimethacrylate (EDMA) as crosslinker, 1,4-butanediol (BDO) and diethylene glycol (DEG) as binary porogenic solvents, and azobisisobutyronitrile (AIBN) as initiator. The resulting poly(GMA-co-VPBA-co-EDMA) monolith showed a relatively homogeneous monolithic structure, good permeability and mechanical stability. Different ratios of monomers and porogens were used for optimizing the properties of monolithic column. The column performance was assessed by the separation of a series of neutral solutes, charge solutes, phenols and anilines. Compared with poly(GMA-co-EDMA) monolith, the proposed monolith exhibited more flexible adjustment of selectivity in terms of hydrophobic, hydrophilic, as well as cation-exchange interaction in the same chromatographic conditions. High column efficiencies for benzene derivatives with 70,000–102,000 theoretical plates/m could be obtained at a linear velocity of 0.265 mm/s. The run-to-run, column-to-column, and batch-to-batch repeatabilities of the retention times were less than 8.23%. Additionally, the purposed monolith was also applied to efficient separation of alkaloids and proteins for demonstrating its potential in biomolecule separation.
研究领域:
分析化学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
SYNTHETIC METALS
·
2023
·
IF 4.4
Shuai Fu,Yuhui Ma,Zhiyuan Zhang,Yao Xu,Heyi Zhang,Zihan Xiao,Sihao Zhang,Ruidong Xia
A high-quality perovskite film is of great significance for efficient and stable perovskite solar cells (PSCs). The use of additives to improve the crystallinity and morphology of perovskite films is an effective way to improve the performance of PSC devices. In this work, 4-carboxyphenyl isothiocyanate (CPIC) was used as an additive in perovskite films to improve the quality of the films. The results of FT-IR showed that the SCN - and -COOH groups with Lewis base in CPIC can coordinate with unpaired Pb 2+ on the perovskite films to form Lewis acid-base adducts. The addition of CPIC can effectively improve the crystallinity and grain size of the perovskite films. The results showed that the short circuit current density ( J SC ) and fill factor (FF) of PSC devices increase significantly with the improvement of film quality, when the concentration of CPIC is 0.5 mg mL −1 . These made the efficiency of the devices increase from 16.16 % to 18.19 %. Meanwhile, the introduction of the benzene ring in CPIC can improve the stability of the PSC devices. After aging at room temperature and 50 % humidity for 30 days, the device added with CPIC retained 61.9 % of the initial PCE. This work proves that using CPIC as an additive is an effective method to achieve efficient and stable PSCs.
研究领域:
材料科学
·
可再生能源
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太阳能电池
·
化学
✓ 已验证
DOI
高影响因子
POLYMER
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2018
·
IF 3.483
Jun Cheng,Zhiqiang Zhang,Wenxin Shi,Ruijun Zhang,Bing Zhang,Xian Bao,Yuan Guo,Fuyi Cui
In this study, 4-dimethylaminopyridine (DMAP) was firstly used as a catalyst in the interfacial polymerization of pentaerythritol (PE) and trimesoyl chloride (TMC) to enhance membrane performance. A series of nanofiltration membranes were prepared using five different DMAP concentrations of 0%, 10%, 20%, 30% and 40% (mass percentage accounting for PE). The filtration test results demonstrated that the water permeability of the typical PE-4 (40% DMAP addition) was 3.47-fold higher than that of the PE-0 (no DMAP addition) with no significant salt rejection loss, indicating that DMAP could effectively improve the water permeability. Characterization by SEM, AFM , and ATR-FTIR indicated that DMAP facilitated the reaction of PE and TMC, which resulted in polyester forming on the surface of the substrate membrane, rather than blocking the membrane pore. Moreover, the PE-DMAP-TMC TFC membrane displayed excellent dye separation performance and high antifouling ability.
研究领域:
材料科学
·
环境工程
✓ 已验证
DOI
高影响因子
Sustainable Energy & Fuels
·
2022
·Vol. 6
·期 11
·2745-2754
·
IF 6.813
Hua Tan,Xuecheng Li,Hao Ma,Xiaolin Yang,Tong Zhan,Wenyu Xie,Suhua Wang,Jiaping Zhu
Herein, N-doped carbon embedded Ni catalysts were prepared by a co-impregnation method followed by pyrolysis in a N2 atmosphere for transfer hydrogenolysis of lignin β-O-4 alcohol and ketone model compounds using isopropanol as the hydrogen source. It was found that pyrolysis at 800 °C resulted in the formation of graphitic N-doped carbon shell encapsulated Ni nanoparticles (Ni@NC-800). The obtained Ni@NC-800 exhibited higher activity and selectivity to aromatics in the conversion of 2-phenoxy-1-phenylthanol and 2-phenoxyacetophenone, compared with Ni@NC-600 and Ni/NC-800. Moreover, the selectivity to aromatics could be further improved over Ni@NC-800-H, which is Ni@NC-800 after strong acid leaching. However, the presence of Cα–OH in lignin β-O-4 model compounds was essential for their product distributions. The control and characterization experiments suggested that the catalytic reaction occurred on the surface of N-doped carbon shells, because the encapsulated Ni NPs could donate electrons to the outer shells, leading to surface electron enrichment, thus making inert shells the new active sites in Ni@NC-800-H. In addition, Ni@NC-800-H was efficient for the conversion of various lignin β-O-4 alcohol and ketone model compounds with methoxyl groups with high yields of the aromatic products and also possessed high stability during consecutive reaction runs, which is because Ni nanoparticles are physically isolated from the reactive environment.
研究领域:
化学工程
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催化材料
·
可再生资源转化
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2024
·
IF 5.8
Chang Miao,Meiling Ma,Yingrui Sui,Yue Cui,Zhanwu Wang,Lili Yang,Fengyou Wang,Xiaoyan Liu,Bin Yao
Environmentally benign and earth-abundant constituent’s kieserite Cu 2 ZnSn (S, Se) 4 (Cotises) is considered as a hopeful photovoltaic material. Unfortunately, the severe tail state caused by various harmful deep defects in CZTSSe absorber prevents further development of its device efficiency. Here, we report firstly that the Co was incorporated into CZTSSe films to form the Cu 2 Co x Zn 1-x Sn (S, Se) 4 (CCZTSSe) films using a two-step annealing and solution-processing technique method. Through optimized the Co/(Co+Zn) ratio, the CCZTSSe film has excellent good surface morphology and single-phase composition. Appropriate amount of Co elements replacing Zn elements in CZTSSe films can effectively reduce the degree of Cu-Zn disorder, thus inhibiting [2Cu Zn +Sn Zn ] defect clusters and Cu Zn defects. The detrimental deep defects located in the film were effectively passivated to reduce electrostatic potential fluctuations, resulting in relief of the trailing state. Therefore, a champion device having an efficiency of 7.50 % with a fill factor (FF) of 61.00 % was achieved from CCZTSSe with 3 % Co content. This work provides new insights into the impacts of Co doping in CZTSSe by a solution processed method and offers a deeper comprehension of the origin of the efficiency enhancement of CCZTSSe devices.
研究领域:
材料科学
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能源技术
·
半导体物理
✓ 已验证
DOI
高影响因子
ENZYME AND MICROBIAL TECHNOLOGY
·
2024
·
IF 3.4
Quan Luo,Guan Zhou,Zhongxia Li,Jiangpeng Dong,Hang Zhao,Huifang Xu,Xuefeng Lu
The chiral amine ( R )-2-(1-aminoethyl)-4-fluorophenol has attracted increasing attentions in recent years in the field of pharmaceuticals because of its important use as a building block in the synthesis of novel anti-tumor drugs targeting tropomyosin receptor kinases. In the present study, a ω-transaminase (ωTA) library consisting of 21 ( R )-enantioselective enzymes was constructed and screened for the asymmetric biosynthesis of ( R )-2-(1-aminoethyl)-4-fluorophenol from its prochiral ketone. Using ( R )-α-methylbenzylamine, D-alanine, or isopropylamine as amino donor, 18 ωTAs were identified with target activity and the enzyme AbTA, which was originally identified from Arthrobacter sp. KNK168, was found to be a potent candidate. The E. coli whole cells expressing AbTA could be used as catalysts. The optimal temperature and pH for the activity were 35–40 °C and pH8.0, respectively. Simple alcohols (such as ethanol, isopropanol, and methanol) and dimethyl sulfoxide were shown to be good cosolvents. High activities were detected when using ethanol and dimethyl sulfoxide at the concentrations of 5–20%. In the scaled-up reaction of 1-liter containing 13 mM ketone substrate, about 50% conversion was achieved in 24 h. 6.4 mM ( R )-2-(1-aminoethyl)-4-fluorophenol was generated. After a simple and efficient process of product isolation and purification (with 98.8% recovery), 0.986 g yellowish powder of the product ( R )-2-(1-aminoethyl)-4-fluorophenol with high ( R )-enantiopurity (up to 100% enantiomeric excess) was obtained. This study established an overall process for the biosynthesis of the high value pharmaceutical chiral amine ( R )-2-(1-aminoethyl)-4-fluorophenol by ωTA. Its applicable potential was exemplified by gram-scale production.
研究领域:
生物化学
·
制药工程
·
酶催化
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL ENGINEERING SCIENCE
·
2013
·Vol. 30
·期 6
·294-301
·
IF 1.154
Lejin Xu,Jianlong Wang
Degradation of 4-chloro-3,5-dimethylphenol (PCMX) by a heterogeneous Fenton-like process using nanoparticulate zero-valent iron (nZVI) and hydrogen peroxide (H2O2) at pH 6.3 was investigated. Interactive effects of three factors—initial PCMX concentration, nZVI dosage, and H2O2 concentration—were investigated using the response surface method based on the Box–Behnken design. Experimental results showed that complete decomposition of PCMX and 65% of total organic carbon removal were observed after 30 min of reaction at neutral pH under recommended reaction conditions: nZVI, 1.0 g/L; H2O2, 18 mM; and initial PCMX concentration, 0.15 g/L. Based on the effects of scavengers n-butanol and KI, removal of PCMX was mainly attributed to the attack of •OH, especially the surface-bonded •OH. A possible degradation pathway of PCMX was proposed.
研究领域:
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Yijie Wang,Yue Huang,Yan Zhang,Henan Wang
Staphylococcal enterotoxins as common bacterial toxins can bring about food contamination and lead to severe foodborne illnesses, so facile and sensitive detection of staphylococcal enterotoxins is significant to ensure food safety and protect public health. In this work, an ultrasensitive biosensor for staphylococcal enterotoxin B (SEB) detection is developed based on the novel electrochemical nanoprobe named MXene/AgNPs@pSC4/MB, which is prepared by functionalizing MXene with para-sulfonatocalix[4]arene-decorated silver nanoparticles (AgNPs@pSC4) and electroactive signal molecules methylene blue (MB). The collaborative effect of AgNPs and MXene endows the fabricated electrochemical nanoprobe with excellent conductivity and admirable loading capacity of signal molecules to significantly enhance the response of biosensor, while pSC4 as the robust linker can bridge the nanoprobe and target SEB by binding with multifarious amino acid residues on SEB. With the specific aptamer immobilized on the electrode as the identifying element to capture SEB, the electrochemical nanoprobes MXene/AgNPs@pSC4/MB are anchored to SEB via pSC4, producing remarkably amplified signal output. The proposed electrochemical biosensor facilitates the ultrasensitive detection of SEB with a low detection limit of 1.76 × 10 −7 ng/mL in addition to the merits of facile operation and rapid response. Moreover, benefiting from the high chemical stability and good resistance to fouling and passivation of the electrochemical nanoprobe, the biosensor exhibits long-lasting stability, good accuracy and anti-interference ability in SEB detection. The reliable detectability of the biosensor has also been examined in the analysis of real food samples, demonstrating potential application toward food safety monitoring.
研究领域:
食品安全检测
·
生物传感
·
纳米技术
·
微生物学
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 17
·7035-7041
·
IF 3.288
Mufei Liu,Hao Yang,Zewen Xu,Wenlu Ma,Fang Cui,George Lu,Linxu Xu,Tieyu Cui
Based on green chemistry, 3D hierarchical ZnO microflowers (MFs) constructed from layered 2D nanosheets have been designed as carriers to uniformly load PdO/Pd nanoparticles by the calcination of the precursor (ZnO/Pd(II) microflowers) in air. The ZnO/Pd(II) microflowers are prepared by dipping the 3D ZnO MFs in an ethanolic solution of PdCl2 without involving additional agents. The as-prepared 3D hierarchical ZnO microflowers are a stable support to enhance the dispersibility of PdO/Pd nanoparticles to achieve better catalytic performance for the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP). In addition, the synergistic effect between the PdO and Pd nanoparticles is another major driver that promotes the catalytic process. Over 98% of 4-NP is reduced within 7 min. Furthermore, structural analysis of the ZnO/PdO/Pd microflowers can provide useful information for understanding structure-performance relationships.
研究领域:
材料科学
·
催化化学
✓ 已验证
DOI
高影响因子
ACS Applied Nano Materials
·
2021
·
IF 5.097
Shijian Zhou,Chunxia Liu,Weiming Jin,Lingling Pan,Qichao Jiang,Yingjie Hu,Yan Kong
Noble-metal nanoparticles (NPs), due to their high surface energy, suffer from serious problems, such as ease of agglomeration at high temperatures, which unfortunately causes a significant decline in their original catalytic activity during the reaction and recycling processes. To solve these problems, in this work, a multiple-step synthetic method is proposed to construct an advanced core–shell structure by anchoring ultrasmall Au nanoparticles on the inner surface of mesoporous Co3O4 (m-Co3O4). The m-Co3O4, which has a high surface area, is fabricated by a hard-templating method, and the ultrasmall Au NPs (1.9 nm) are confined to the inner surface of the m-Co3O4. The target sample of Au–m-Co3O4 is found to achieve the highest catalytic efficiency in the probe reaction of the catalytic reduction of 4-nitrophenol to 4-aminophenol, and more importantly, thermal stability tests demonstrate that the Au–m-Co3O4 catalyst is more stable at higher temperatures. Furthermore, DFT calculations have verified that both activated hydrogen adsorption and 4-aminophenol desorption are significantly promoted on the surface of the Au–m-Co3O4 catalyst due to a strong synergetic effect between Au and the m-Co3O4. The construction of this advanced architecture for Au-based catalysts could provide a facile method for stabilizing ultrasmall noble-metal NPs and reasonably designing noble-metal catalysts with desirable activity and stability.
研究领域:
材料科学
·
催化化学
·
理论计算化学
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL RESEARCH
·
2025
·
IF 7.7
Liang Zeng,Qilin Wang,Xinyi Lou,Chang Peng,Ruoxi Wu,Shu Chen
Responsive catalysts with self-healing response capabilities will have great potential in sustainable catalytic applications, effectively extending the lifespan of catalysts. Herein, a near-infrared-responsive self-repairing composite gel catalyst is presented for efficient and sustainable reduction of 4-nitrophenol (4-NP, i.e., a specific organic pollutant). Copper nanoparticles (CuNPs) serve as catalytic species, while transition metal carbide (Ti 3 C 2 T x ) acts as efficient electron transfer medium in the composite gel. The synergistic effect of these components significantly enhances catalytic activity of the gel (e.g., the catalytic rate constant k for 4-NP reduction reaches up to 0.6159 min −1 ). More importantly, by leveraging the self-healing of poly(N, N-dimethylacrylamide) (PDMAA, i.e., the third component in the gel) and combining the photothermal conversion of Ti 3 C 2 T x , the gel is endowed with the ability to rapidly repair itself by near-infrared light induction, thereby ensuring its sustainability in the catalytic application. This photo-induction way not only effectively repairs the damaged gel catalyst but also preserves its catalytic efficiency, making it ideal for prolonged application. This research offers novel insights into using responsive catalysts to achieve sustainable and efficient catalytic application.
研究领域:
材料化学
·
环境催化
·
纳米催化
·
高分子凝胶
·
光响应材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Cell Reports
·
2023
·Vol. 42
·期 11
·113349-113349
·
IF 8.8
Shao Q,Wijaya CS,Wang S,Meng X,Yuan C,Ma C,Xu S
Maintaining cellular viability relies on the integrity of the plasma membrane, which must be repaired upon damage. Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)-mediated membrane fusion is a crucial mechanism involved in membrane repair. In C. elegans epidermal cell hyp 7, syntaxin-2 (SYX-2) facilitates large membrane wound repair; however, the underlying molecular mechanism remains unclear. Here, we found that SNAP-25 protein RIC-4 and synaptobrevin protein SEC-22 are required for SYX-2 recruitment at the wound site. They interact to form a SNARE complex to promote membrane repair in vivo and fusion in vitro. Moreover, we found that SEC-22 localized in multiple intracellular compartments, including endosomes and the trans-Golgi network, which recruited to the wounds. Furthermore, inhibition of RAB-5 disrupted SEC-22 localization and prevented its interaction with SYX-2. Our findings suggest that RAB-5 facilitates the formation of the RIC-4/SEC-22/SYX-2 SNARE complex and provides valuable insights into the molecular mechanism of how cells repair large membrane wounds.
研究领域:
细胞生物学
·
分子生物学
·
发育生物学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）