Reaction Chemistry & Engineering
·
2024
·
IF 3.4
Shan Huang,Jiajia Liu,Lingxin Kong,Mengmeng Wang,Yi Liu,Yi Fang,Qi Xiao
This study reports the synthesis of Er-doped, Mn-doped, and Er, Mn co-doped monoclinic BiVO4 photocatalysts via a facile one-pot hydrothermal method. Er6%Mn2%/BiVO4 exhibited a larger specific surface area, bigger pore volume, and smaller average pore size compared to pure BiVO4 and single-doped BiVO4. The co-doping of Er3+ and Mn2+ ions resulted in lattice distortion and crystal particle size reduction of BiVO4, and generated a new impurity level at the bottom of the conduction band, narrowing the band gap and widening the absorption edge of visible light, thus improving the separation efficiency of photogenerated electron–hole pairs. Photocatalytic experiments on rhodamine B showed that Er6%Mn2%/BiVO4 achieved a degradation efficiency of 97.8% under visible light irradiation (λ >420 nm) within 100 min, which is higher than those of BiVO4, Er6%/BiVO4, and Mn6%/BiVO4. The kinetic rate constant (0.0312 min−1) of Er6%Mn2%/BiVO4 was 1.3, 2.2, and 4.7 times higher than those of Er6%/BiVO4, Mn6%/BiVO4, and BiVO4, respectively. The study also identified ·O2− and h+ as the predominant active species involved in the photocatalytic degradation of rhodamine B and demonstrated the excellent stability of Er6%Mn2%/BiVO4 for five cycles of photodegradation experiment. This work highlights that Er6%Mn2%/BiVO4 has great potential as a candidate for treating organic pollutants in water.
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DOI
高影响因子
TALANTA
·
2017
·
IF 4.162
Yaoyao Zhou,Bo Ling,Hongqi Chen,Lun Wang
A novel fluorescence method for the determination of hydrogen peroxide (H 2 O 2 ) and uric acid (UA) was developed. The procedure was based on the hydroxyl radicals (·OH), which effectively quenched the fluorescence of the Mn 2+ -doped NaYF 4 :Yb,Er upconversion nanoparticles (UCNPs). Based on the property of Mn 2+ -doped NaYF 4 :Yb,Er upconversion nanoparticles, the Fenton reaction and enzymatic reaction of uric acid, this method could be used for highly sensitive detection of H 2 O 2 and uric acid. Under optimal conditions, we observed that the fluorescence quenching signal showed good linearity with the H 2 O 2 concentration in the range of 3.00 × 10 -8 M ~ 6.00×10 -5 M, and the detection limit of this assay was 1.30×10 -8 M. Meanwhile, the linear concentration range for UA was 4.00 × 10 -9 M ~ 1.00×10 -5 M, and the lower limit of detection was 1.90×10 -9 M. Furthermore, the developed method was successfully used for the determination of UA levels in human serum with satisfactory results.
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PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Zhengren Tao,Fangrui Cheng,Yinghan Wang,Sijie Su,Enhai Song,Jiulin Gan,Shi Ye
The arrangement of lithium and niobium in the LiNbO 3 lattice is crucial to its notable ferroelectric, piezoelectric, ion conductive, and nonlinear optical properties. However, the synthesis of Li concentration-gradient nanocrystals remains a significant challenge. In this paper, we report a reliable method for synthesizing LiNbO 3 : Yb/Er nanocrystals with a Li-gradient through topochemical molten salt synthesis. We elucidate the Li-gradient characteristics using various analytical techniques, including depth-dependent elemental analysis. Variable-temperature upconversion luminescence spectroscopy provided insights into thermally induced surface and interior Li + diffusion. Our findings demonstrate that Li-gradient nanocrystals exhibit enhanced ferroelectric behavior and increased sensitivity to mechanical force in upconversion emission response. This study proposes a feasible universal strategy for synthesizing alkali metal niobate materials with controlled polarization, offering promising candidates for flexible, low-power optoelectronic devices.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Wei Zhou
Traditional optical temperature sensors rely on strong fluorescence emission materials, high-homogeneity nanoparticles, and individual temperature calibration to ensure measurement accuracy and reliability. However, these requirements inevitably introduce disadvantages such as significant time costs, extensive labor inputs, and challenges in material synthesis, which hinder large-scale applications. Consequently, this paper investigates the effects of size, homogeneity, metal doping, and core-shell structures of rare-earth nanoparticles on the thermally coupled energy levels ( 2 H 11/2 and 4 S 3/2 ) of Er-based upconversion nanoparticles (UCNPs). The nanoparticles NaLuF 4 :Yb,Er, NaLuF 4 :Yb,Er,Li, NaLuF 4 :Yb,Er,Mg and NaLuF 4 :Yb,Er@NaLuF 4 :Yb,Tm@NaLuF 4 were prepared using a thermal decomposition method. The morphology and luminescence properties of the four UCNPs were characterized through transmission electron microscopy and fluorescence spectrophotometry. Additionally, variable-temperature luminescence intensity measurements of the four UCNPs were conducted under 980 nm laser excitation. The experimental results demonstrate a strong linear relationship between temperature and the luminescence intensity ratios (LIRs) of the thermally coupled energy levels of Er-based UCNPs with varying shapes, sizes, core-shell structures, and luminescence intensities. Notably, the fitted straight lines relating LIR for different Er-based UCNPs to temperature exhibit approximately equal slopes (sensitivity). This characteristic allows for the calibration of thermometers using only a single temperature point, significantly simplifying the calibration process. Furthermore, the synthesis of the materials is streamlined, enabling mass production without the need to consider the homogeneity and symmetry of the material. Therefore, thermometers based on rare-earth Er-based UCNPs hold significant potential for large-scale production and application.
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2025
·
IF 6.1
Jie Tang,Bairu Chen,Fang Yu,Long Xu,Muxin Yu,Chunji Wang,Fang Zhang,Li Zhang,Yujia Yang,Jiani Hou,Xingfei Li,Weihao Xu,Nenghua Zhang
Increasing evidence links hearing loss to environmental pollutant exposure, with cochlear hair cell being a key target. Bisphenol A (BPA) has been suggested to cause ototoxicity, but its mechanism is not fully understood. In this study, cell viability was assessed by varying concentrations of BPA (0–150 μM) exposed to mouse cochlear hair cells (HEI-OC1), followed by RNA transcriptome sequencing to identify the possible molecular mechanisms. Results showed that BPA above 50 μM reduced cell viability in a dose-dependent manner. RNA sequencing identified 1764 differentially-expressed genes, comprised of 1152 up-regulated and 612 down-regulated genes. Notably, estrogen receptor-related genes were enriched, with a marked up-regulation of estrogen receptor α (ER-α) at both mRNA and protein levels. GO and KEGG analyses revealed the main pathway involvement for oxidative damage, lipid metabolism, protein phosphorylation, and DNA damage. STRING analyses constructed gene networks to identify functionally interacting genes correlated with pyroptotic pathways. BPA exposure induced pyroptosis-like morphological changes characterized by cell swelling, rounding, and membrane blebbing. Increased intracellular ROS and mitochondrial superoxide (MitoSOX) levels, reduced mitochondrial membrane potential ( ΔΨm ), and elevated intracellular calcium (Ca²⁺) levels were observed. Flow cytometry showed an increased proportion of apoptotic and necrotic cells. Pyroptosis-related genes, including caspase-3, caspase-8, caspase-9, and GSDME, were down-regulated, while IL-1β and IL-18 were up-regulated. Protein expressions of caspase-3, caspase-8, caspase-9, and GSDME were decreased, while cleaved caspase-3 and N-terminal GSDME (GSDME-NT) were increased. Furthermore, ROS inhibitor N-acetylcysteine (NAC) and the ER-α antagonist fulvestrant alleviated BPA-induced cell death, and suppressed the protein expressions of the pyroptotic pathway. These results demonstrate that BPA exposure induces ototoxicity possibly through activating ER-α and triggering mitochondrial ROS that contributes to pyroptosis.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Jiaxin Wang,Yifan Wang,Huixin Qiu,Huixia Zhu,Zhenyu Wang,Yue Li,Youshun Jia
We systematically study the crystal structure, magnetism and cryogenic magnetocaloric effect (MCE) in heavy rare-earth RE 6 MoO 12 ( RE = Tb, Dy, Ho, and Er) compounds. All RE 6 MoO 12 compounds belong to a cubic structure (space group: F m 3 − m ). Meanwhile, magnetic measurements illustrate that RE 6 MoO 12 compounds exhibit an antiferromagnetic (AFM) phase transition. It is proved by the slope of the basic Arrott-plots that all compounds undergo second-order magnetic phase transition (SOMT). In addition, under the applied magnetic change ΔH = 7 T, the maximum magnetic entropy change (-∆ S M max ) near Néel temperature ( T N ) is evaluated to be 12.9, 20.7, 21.1, and 21.2 J/kg K, and relative cooling power ( RCP ) is evaluated to be 308.3, 473.9, 506.2, and 381.4 J/kg for Tb 6 MoO 12 , Dy 6 MoO 12 , Ho 6 MoO 12 , and Er 6 MoO 12 , respectively. Consequently, our study underscores the magnetism and magnetocaloric effect properties exhibited by heavy rare-earth RE 6 MoO 12 compounds family, positioning them as a potential magnetic refrigerant in the field of low-temperature magnetic refrigeration.
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高影响因子
OPTICAL MATERIALS
·
2025
·
IF 4.2
Haoran Zhang,Tianxi Feng,Song Ye,Deping Wang
In this research, the modified upconversion nanocrystals NaYF 4 :Yb,Er were adopted as the precursors for the synthesis of the NaYF 4 :Yb,Er@UiO-66 composite. The XRD, XPS and TEM characterizations indicated that the composite has good crystallinity and uniform morphology. Under 980 nm excitation, the NaYF 4 :Yb,Er@UiO-66 composite exhibits bright upconversion emission that characterized of Er 3+ : 2 H 11/2 → 4 I 15/2 , 4 S 3/2 → 4 I 15/2 , and 4 F 9/2 → 4 I 15/2 radiative transitions. After modified with BPEI (branched polyethyleneimine), the NaYF 4 :Yb,Er@UiO-66/BPEI fluorescence probe was constructed and was used for the detection of Cu 2+ . The results revealed that the integrated emission intensity of Er 3+ displayed a linear relationship with the concentration of Cu 2+ within the range of 5 to 45 μM with a LOD of 0.9615 μM. This study offered a feasible method for constructing UCNC@UiO-66 composites with regular morphology,which may have a potential application as fluorescent probes for the detection of various metal ions by adjusting the doping luminescent center.
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高影响因子
Journal of Superconductivity and Novel Magnetism
·
2025
·Vol. 38
·期 6
·231
·
IF 1.7
Liu Wanxia,Gao Yuxia,Li Yaning,Li Yulong,Ren Weijie,Sun Xin,Li Xiaofeng,Wang Mingli
The synthesis, structure, and magnetic properties of Ba 3 REB 9 O 18 (RE = Dy-Yb) compounds were investigated. Rietveld Refinement of the X-ray diffraction (XRD) data confirms that all compounds crystallize in a hexagonal Ba 3 YB 9 O 18 -type structure with space group P 6 3 /m (No. 176) and Pearson symbol hP 62. The lattice parameters a and c increase linearly with the increasing ionic radii of the RE 3+ ions. RE 3+ ions form two-dimensional triangular layers in the ab plane, which are separated by non-magnetic Ba/B-O polyhedra. The magnetic susceptibility measurement reveals no long-range magnetic order or spin glass behavior in any of the compounds above 2 K. The negative Curie-Weiss temperatures indicate dominant antiferromagnetic (AFM) exchange interactions between the RE 3+ ions. The combination of triangular lattice and antiferromagnetic interaction suggests this family of compounds is a promising system for researching magnetic frustration.
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高影响因子
CANCER RESEARCH
·
2024
·
IF 12.5
Fang Liang,Zhang Li,Wang Mengran,He Yuhao,Yang Jiao,Huang Zengjin,Tan Ying,Fang Ke,Li Jun,Sun Zhiyuan,Li Yanping,Tang Yisen,Liang Weizheng,Cui Huanhuan,Zhu Qionghua,Wu Zhe,Li Yiming,Hu Yuhui,Chen Wei
Epithelial-mesenchymal transition (EMT) is a fundamental cellular process frequently hijacked by cancer cells to promote tumor progression, especially metastasis. EMT is orchestrated by a complex molecular network acting at different layers of gene regulation. In addition to transcriptional regulation, post-transcriptional mechanisms may also play a role in EMT. Here, we performed a pooled CRISPR screen analyzing the influence of 1547 RNA binding proteins (RBPs) on cell motility in colon cancer cells and identified multiple core components of P-bodies (PBs) as negative modulators of cancer cell migration. Further experiments demonstrated that PB depletion by silencing DDX6 or EDC4 could activate hallmarks of EMT thereby enhancing cell migration in vitro as well as metastasis formation in vivo. Integrative multi-omics analysis revealed that PBs could repress the translation of the EMT-driver gene HMGA2, which contributed to PB-meditated regulation of EMT. This mechanism is conserved in other cancer types. Furthermore, endoplasmic reticulum (ER) stress was an intrinsic signal that induced PB disassembly and translational derepression of HMGA2. Taken together, this study has identified a function of PBs in regulation of EMT in cancer.
研究领域:
癌症生物学
·
分子生物学
·
细胞生物学
·
遗传学
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高影响因子
JOURNAL OF APPLIED PHYSICS
·
2021
·Vol. 129
·期 5
·
IF 2.546
Jiao Yan,Guo Mengting,Wang Renle,Shao Chongyun,Hu Lili
In this study, Er 3+ /Al 3+ co-doped silica glasses with various Al/Er ratios ranging from 0 to 200 and a constant Er 2 O 3 amount were prepared using the sol-gel method combined with high-temperature vacuum sintering. The absorption, emission spectra, and fluorescence lifetime of Er 3+ ions were recorded and the absorption and emission cross sections were calculated. Using Raman, 27 Al and 29 Si magic angle spinning nuclear magnetic resonance (MAS-NMR), 27 Al triple-quantum (TQ)-MAS-NMR, and electron paramagnetic resonance (EPR) spectroscopies, the physical and optical properties were correlated with the glass structural modifications due to the Al/Er ratio change. With the increase in the Al/Er ratio, the content of Al 3+ ions around the Er 3+ ions gradually increased. Meanwhile, the AlO 5 and AlO 6 polyhedrons increased at the expense of the AlO 4 and SiO 4 tetrahedrons, which resulted in an improved symmetry and better ionic Er–O bonds. These structural changes led to the site-to-site variations in the Er 3+ local environment and the changes in the ligand field strength of the Er–O bonds. This, in turn, resulted in the inhomogeneous broadening of the absorption and emission spectra, with a blue shift of both absorption and emission peaks and a decrease in both absorption and emission at 1.53 μ m. With the increase in Al/Er ratio, the full width at half maximum (FWHM) of the emission increased from 27.2 to 54.3 nm. The FWHM × emission cross section ( σ e m i ) parameter for evaluating broadband amplification behavior was 30.1 × 10 −20 cm 2 · nm. This work reveals the close relationship between the glass structure and the spectroscopic properties of Er 3+ ions and provides an important reference for the design of broadband amplifier materials in the field of optical communication.
研究领域:
材料科学
·
光学
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高影响因子
ACS Sustainable Chemistry & Engineering
·
2020
·
IF 7.632
Xiaokai Xu,Wei Li,Chaofan Hu,Bingfu Lei,Xuejie Zhang,Yadong Li,Qiuqiang Zhan,Yingliang Liu,Jianle Zhuang
In recent years, the application of nanomaterials in promoting plant growth and augmenting photosynthesis has aroused great interest. Herein, carbon dots (CDs) are combined with NaYF4:Yb,Er to achieve an enhanced upconversion red emission. The effects of the obtained NaYF4:Yb,Er@CDs nanocomposites on the growth of mung bean plants are investigated. It is found that an appropriate concentration of the NaYF4:Yb,Er@CDs nanocomposites (0.5 mg/mL) can enhance the water absorption ability of hydroponic mung beans and promote their growth after incubation for 7 days. Confocal imaging shows that the nanocomposites can transfer from the roots to the stems and leaves. Interestingly, after spraying the nanocomposite solution on the surface of the mung bean seedling leaves and placing them under sunlight for 2 weeks, the root/stem lengths and wet/dry weight clearly increase. Moreover, the photosynthetic rate of the mung bean seedling is found to increase by more than 2 times, while the transpiration rate and stomatal conductance are improved by 144 and 148%, respectively. Such a promoting effect is ascribed to the ability of the NaYF4:Yb,Er@CDs nanocomposites to convert near-infrared (NIR) radiation into red light, which is beneficial for plant photosynthesis. This work provides a promising strategy for promoting plant growth by the application of nanomaterials.
研究领域:
植物学
·
纳米生物学
·
农业科学
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高影响因子
CHEMICO-BIOLOGICAL INTERACTIONS
·
2016
·
IF 2.618
Pianpian Chen,Yongmei Shen,Hongxue Shi,Xiuying Ma,Beibei Lin,Tong Xiao,Fenzan Wu,Jingjing Zhu,Zhengmao Li,Jian Xiao,Xiaokun Li,Hongyu Zhang,Funeng Geng
Oxidative stress and ER stress play a role in the pathogenesis of gastric ulcer . Kangfuxin (KFX) has been used to treat gastric ulcer in patients. However, the underlying mechanisms of KFX action remain unclear. The current study was undertaken to evaluate the gastroprotective effects of KFX and to determine its potential mechanisms. Ethanol-induced gastric ulcer mouse model was employed. Ethanol pretreated mice were treated with low (0.02 g/kg) and high (0.05 g/kg) dose of KFX for 14 days. Cimetidine (0.8 g/kg) was used as positive control. Histological evaluation of the gastric mucosa revealed that mice treated with ethanol exhibited severe gastric mucosal damage. Ethanol treatment increased plasma and gastric MDA level, decreased plasma and gastric SOD activity, and reduced gastric HO-1 and GCL-c mRNA levels. ER stress markers (CHOP, GRP78 , and caspase 12) were up-regulated upon ethanol administration. Moreover, increased cell apoptosis and pro-apoptotic protein Bax and caspase 3 were observed in ethanol treated mice, while the anti-apoptotic protein Bcl 2 was inhibited. Finally, KFX treatment reversed ethanol-induced phenotypes and ameliorated gastric ulcer. Our results demonstrated that the gastroprotective effects of KFX against ethanol-induced gastric ulcer could be attributed to its anti-oxidative stress, anti-ER stress and anti-apoptotic effects.
研究领域:
药理学
·
胃肠病学
·
分子生物学
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高影响因子
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