Advanced Healthcare Materials
·
2019
·Vol. 8
·期 23
·1900911
·
IF 6.27
Peng Ji,Haiqin Huang,Shirui Yuan,Le Wang,Siqi Wang,Yiwei Chen,Na Feng,Hanitrarimalala Veroniaina,Ziheng Wu,Zhenghong Wu,Xiaole Qi
Reactive oxygen species (ROS)-mediated apoptosis is considered a crucial therapeutic mechanisms for artesunate (AS). As an Fe(II)-dependent drug, the anticancer effect of AS is often limited due to insufficient Fe(II) concentration in targeted cells. To overcome this problem, a recombinant apoferritin nanocarrier containing ferriferous oxide (M-HFn) is constructed to produce auxiliary exogenous Fe(II) when delivering AS to cancer cells. Here, the newly fabricated AS-loaded M-HFn nanoparticles (M-HFn@AS NPs) can significantly improve the tumor-specific targeting and intracellular uptake efficiency of AS in human cervical carcinoma cells. After being captured in the acidic cavity of endosomes, M-HFn@AS NPs can simultaneously release Fe(II) and allow AS to activate satisfactory ROS-mediated apoptosis. Furthermore, in vivo studies demonstrate that M-HFn@AS NPs can selectively accumulate in tumors to efficiently inhibit tumor growth. Thus, M-HFn@AS NPs are a promising system to enhance the therapeutic effect of Fe(II)-dependent drugs.
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高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 27
·期 5
·5085-5096
·
IF 2.914
Li Haijie,Huang Guofu,Wang Mianmian
2,2′,4,4′-Tretrabromodiphenyl ether (BDE47) is known as a typical polybrominated diphenyl ethers (PBDEs) due to its high environmental abundance, ecological toxicity, and bioaccumulation. In this study, the influences of three typical surfactants (CTAB, SDS, and TX-100) on BDE47 solubilization and degradation by the polyanionic cellulose–stabilized Pd/Fe (PAC-Pd/Fe) nanoparticles were investigated. The results showed that BDE47 solubilities increased linearly when surfactant concentrations were above their critical micelle concentrations (CMCs), and the solubilization capacities of surfactants for BDE47 followed the order of TX-100 > CTAB > SDS. The appropriate dosages of surfactants were favorable for BDE47 degradation due to enhancing solubilization and accelerating mass transfer, while excessive surfactants inhibited BDE47 degradation due to excessive and thicker micelles formed, but still higher than no surfactant. The influences of various factors (PAC-Pd/Fe nanoparticle dosage, solution pH, and temperature) on BDE47 degradation in TX-100 solution were also tested. The results showed that BDE47 degradation followed the pseudo first-order kinetics model. The degradation rates of BDE47 increased as PAC-Pd/Fe nanoparticle dosage and temperature increased. Weak acidic condition (pH 5.5) was favorable for BDE47 degradation with 96.8% BDE47 was removed within 7.5 min, while alkaline condition (9.0) was not conducive to the degradation of BDE47. The degradation of BDE47 by PAC-Pd/Fe nanoparticles was a catalytic reductive debromination process via active H-species attack, wherein the sequential debromination was the dominant reaction. This study suggests that in the presence of moderate surfactant, PAC-Pd/Fe nanoparticles may be potentially employed to eliminate BDE47 in contaminated water.
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Processes
·
2019
·Vol. 7
·期 6
·351
·
IF 1.963
Yali Liu,Xiaorong Kang,Han Cheng
The addition of Fe2+is considered an effective method for increasing methane production, but the added Fe2+may not be absorbed by anaerobic microorganisms due to complex chemical reactions. In this study, ethylenediaminetetraacetic acid (EDTA) was used as a ligand of Fe2+(EDTA-Fe) to promote the dissolution of Fe, and the anaerobic performances of kitchen wastes (KWs) in a semi-continuous reactor were studied. The results indicated that the biogas yields and methane contents were enhanced to 594–613 mL·g−1VSadd·d−1and 63.6–64.4% at an organic loading rate (OLR) of 2.5 gVSadd·L−1·d−1due to EDTA-Fe addition. Simultaneously, the EDTA-Fe was more effective than Fe2+in preventing the acidification of KWs with a high OLR (5.0 gVSadd·L−1·d−1). In addition, the sequential extraction results showed that the water-soluble fraction of Fe in the R3 (EDTA-Fe addition) was 1.49-fold of that in the R2 with Fe2+addition. The contents of coenzymes F420 and F430 were also improved 1.09 and 1.11 times, respectively. Mechanism analysis confirmed that the EDTA enhanced methane production and operational stability by promoting the dissolution of Fe and maintaining a high content of water-soluble Fe.Keywords:semi-continuous reactor;EDTA;Fe;kitchen wastes;methane
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ChemSusChem
·
2019
·Vol. 12
·期 21
·4791-4798
·
IF 7.804
Xiaohao Liu,Chenguang Wang,Ying Zhang,Yan Qiao,Yang Pan,Longlong Ma
Graphical Linked in to lignin : 4-Alkylphenol is produced selectively over a magnetic Co 1 –Fe 0.1 @NC catalyst from real lignin oil as feedstock, which is obtained by a “lignin-first” strategy from raw biomass. The incorporation of Fe attenuates the adsorption of 4-alkylphenol to the catalyst, which inhibits the further hydrogenation of 4-alkylphenol to 4-alkylcyclohexanol. Lignin valorization to produce high-value chemicals selectively is an enormous challenge in biorefinery. In this study, 4-alkylphenol, formed by breaking the robust C aryl −OCH 3 bonds solely with the retention of other structures in lignin-derived methoxylalkylphenols, was produced selectively over a Co 1 –Fe 0.1 @NC catalyst from real lignin oil as feedstock, which was obtained by a “lignin-first” strategy from either birch or cornstalk. A yield of 64.7 or 88.3 mol % of 4-propylphenol was obtained if birch lignin oil or eugenol was used as the substrate, respectively. The catalysts were characterized by using methods that include Brunauer–Emmett–Teller measurements, XRD, X-ray photoelectron spectroscopy, high-resolution transmission electron microscopy, high-angle annular dark-field scanning transmission electron microscopy, energy-dispersive X-ray spectroscopy, and temperature-programmed desorption with synchrotron vacuum ultraviolet photoionization mass spectrometry. The results of catalyst characterization and comparison experiments indicated that CoN x was the main active phase for demethoxylation and hydrogenation, and the incorporation of Fe weakens the adsorption of 4-propylphenol to the catalyst, which inhibits the excessive hydrogenation of 4-propylphenol. This work shows the potential to produce high-value-added 4-alkylphenol from renewable raw biomass.
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CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Xiaoxia Ou,Fotios Pilitsis,Yilai Jiao,Yong Zhang,Shaojun Xu,Martin Jennings,Yi Yang,S.F. Rebecca Taylor,Arthur Garforth,Huiping Zhang,Christopher Hardacre,Ying Yan,Xiaolei Fan
Structured Fe-ZSM-5 zeolite supported on silicon carbide (SiC) foam catalyst was develop and applied as the packed foam bed catalytic reactor (FBCR) to the liquid phase catalytic wet peroxide oxidation (CWPO) of phenol under flow conditions. Fe catalysts were uniformly incorporated into ZSM-5 coatings using chemical vapour deposition (CVD). Fluid flow analysis of FBCR was performed by varying liquid flow rate, showing the transition of reactor type from the plug flow reactor to the continuous stirred tank reactor at about 1 ml min −1 . Systematic investigation of CWPO within Fe-ZSM-5/SiC FBCRs identified the optimum condition of operating the FBCR (80 mm bed length) as at 60 °C and 1 ml min −1 with the turnover frequency (TOF) of 95 h −1 for phenol degradation (apparent activation energy = 3.4 kJ mol −1 ) and total organic carbon (TOC) conversion of 45.5%. It was believed that the enhanced macromixing promoted by cellular foam supports was accountable for the observed catalytic performance. The longevity of FBCR under flow conditions was also assessed, showing its good stability over 24 h, as well as the potential for practical adoption.
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FUEL
·
2018
·
IF 4.908
Qicong Liu,Zhe Xiong,Syed Shatir A. Syed-Hassan,Zengtong Deng,Xingyu Zhao,Sheng Su,Jun Xiang,Yi Wang,Song Hu
Ni-based catalyst is prone to the deactivation by coke deposition during the catalytic steam reforming of bio-oil. In order to optimize catalytic activity of the Ni-based catalyst, a two-stage catalytic reforming scheme was proposed whereby a low-temperature (350–600 °C) pre-reforming process with a less expensive catalyst was introduced prior to the Ni-based catalyst. To study this scheme, the reforming experiments with different combinations of Fe/bio-char (in the first stage) and Ni-Ca/γ-Al 2 O 3 (in the second stage) were conducted. In addition to the quantification of product yields, the tar and gas were characterized with an ultraviolet (UV) fluorescence spectroscopy, a gas chromatography/mass spectrometer (GC/MS) and a gas chromatography (GC). The results indicate that significant proportions of naphthalenes and polycyclic aromatics in the intermediate volatiles turned into furans, phenols and non-aromatics, which are easier to be reformed on Ni-based catalysts, via the Fe/bio-char pre-reforming, resulting in the increase of the final H 2 and CO yields of the overall process. At high pre-reforming temperatures (550–600 °C), the coke formation on Ni-based catalyst was significantly inhibited due to the Fe/bio-char pre-reforming. In addition, the results indicate that the spent Ni-based catalyst had more free NiO and NiAl 2 O 4 spinel than the fresh one, suggesting that the increase in the catalytic activity of Ni-based catalyst during the reforming process was promoted by Fe/bio-char pre-reforming.
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ENERGY CONVERSION AND MANAGEMENT
·
2018
·
IF 6.377
Junguang Meng,Zengli Zhao,Xiaobo Wang,Anqing Zheng,Dongyan Zhang,Zhen Huang,Kun Zhao,Guoqiang Wei,Haibin Li
Ni/Fe bimetallic catalysts were synthesized on an olivine support using the wetness impregnation (WI) and thermal fusion (TF) methods, and catalytic cracking and steam reforming on different tar model compounds (phenol and naphthalene) were investigated in a fixed bed reactor. The effects of the reaction temperature and space-time on the catalytic cracking activity of phenol and naphthalene were tested, and the influences of steam on the carbon molar ratio (S/C) and different synthesized methods on the steam reforming of phenol and naphthalene were also studied. In addition, the carbon deposited on the catalyst was analysed using temperature program oxidation (TPO), Raman spectroscopy and transmission electron microscopy (TEM) methods. The elemental composition of the catalyst was analysed by X-ray fluorescence (XRF), and the physiochemical properties of the catalysts were characterized via X-ray diffraction (XRD), the BET surface area, scanning electron microscopy (SEM), TEM, Raman spectroscopy, temperature program reduction (TPR), and X-ray photoelectron spectroscopy (XPS). The results showed that the structure of TF-Ni/Fe/olivine changed considerably compared with that of calcined olivine (mainly the Mg 2 SiO 4 phase) and that a portion of Fe was fused into the olivine structure and reorganized into a new (Mg, Fe) Fe 2 O 4 phase. After reduction, the Ni-Fe alloy was detected on both catalysts, and the particle size of the Ni-Fe alloy on TF-Ni/Fe/olivine was smaller than that of WI-Ni/Fe/olivine. The TF-Ni/Fe/olivine cracked phenol into small-molecule gas (CO and H 2 ) and a small quantity of olefin. By contrast, phenol was polymerized to naphthalene in the absence of a catalyst. The phenol and naphthalene steam reforming conversion on WI-Ni/Fe/olivine were both higher than that of TF-Ni/Fe/olivine. A 100-h stability test of phenol steam reforming on TF-Ni/Fe/olivine and WI-Ni/Fe/olivine was conducted, and TF-Ni/Fe/olivine showed higher stability in the early stages of the experiment due to stronger interactions between the active sites and olivine support. The deposited carbon from naphthalene steam reforming was more difficult to eliminate because it contained more C β and C γ , which had higher degrees of graphitization.
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CHINESE JOURNAL OF CATALYSIS
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2018
·
IF 3.525
Guoqiang Shen,Lun Pan,Zhe Lü,Chongqing Wang,Fazal-e- Aleem,Xiangwen Zhang,Ji-Jun Zou
Adsorption and photodegradation are promising approaches for removing organic pollutions. In this study, we combined these two processes by co-loading Fe-TiO 2 and Fe 2 O 3 quantum dots (QDs) on porous MCM-41, using a simple hydrolysis method. X-ray diffraction, high-resolution transmission electron microscopy, and X-ray photoelectron spectroscopy results indicated that Fe-TiO 2 QDs are formed at low Fe precursor concentrations, while additional Fe 2 O 3 QDs are formed at higher Fe precursor concentrations. The Fe 2 O 3 and Fe-TiO 2 QDs impart high adsorption capacity and high photoactivity to the porous MCM-41, respectively. Thus, their combination results in a synergic effect of the adsorption and photodegradation. The highest-performing sample exhibits excellent performance in removing rose bengal from aqueous solution.
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RSC Advances
·
2018
·Vol. 8
·期 46
·25873-25880
·
IF 2.936
Jie Guo,Yongjiang Hou,Bo Li
A hollow Ni–Fe–B nanochain is successfully synthesized by a galvanic replacement method using a Fe–B nanocomposite and a NiCl2 solution as the template and additional reagent, respectively. Both the concentration of Ni and the morphology of the resulting Ni–Fe–B alloy are controlled by varying the duration of the replacement process during the synthesis. The Ni–Fe–B sample synthesized for 60 min (Ni–Fe–B-60) shows the best catalytic activity at 313 K, with a hydrogen production rate of 4320 mL min−1 gcat−1 and an activation energy for the NaBH4 hydrolysis reaction of 33.7 kJ mol−1. The good performance of Ni–Fe–B-60 towards the hydrolysis of NaBH4 can be ascribed to both hollow nanochain structural and electronic effects. Furthermore, the effects of temperature, catalyst amount, and concentration of NaOH and NaBH4 on the hydrolysis process are systematically studied, and an overall kinetic rate equation is obtained. The hollow Ni–Fe–B nanochain catalyst also shows good reusability characteristics and maintained its initial activity after 5 consecutive cycles.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2018
·
IF 3.927
Ying Liu,Deli Wu,Shuhan Peng,Yong Feng,Zhigang Liu
Cu-Fe-O nanoparticles (CFO NPs), synthesized with zero-valent iron (ZVI) and Cu(NO 3 ) 2 as the metal precursors, were used to enhance ozonation to degrade dimethyl phthalate (DMP). Great DMP degradation and mineralization rates were achieved in a wide range of the initial pH values (3–9); the amount of OH in catalytic ozonation was much higher than that of O 3 alone at the initial pH of 5.70. The generation of hydroxyl radicals ( OH), methyl radicals ( CH 3 ) and superoxide radicals (O 2 − ) were identified and OH mainly contributed to DMP removal. The potential of Fe(III)/ Fe(II) and Cu(II)/ Cu(I) cycles have largely been overlooked, which was found to be the key for producing more OH in CFO/O 3 system. The underlying mechanisms were probably initiated by a chain reaction: initiated O 3 reaction with Cu(I)/ Fe(II) OH to form OH and O 2 − , accelerated reaction between Cu(II)/ Fe(III) and the in situ generated O 2 − with a relatively high reaction constant, redox reaction between Cu(I) and Fe(III), OH oxidizing reaction with DMP to produce CH 3 . In addition, different degradation pathways of DMP were proposed based on the intermediates in the presence of CH 3 . This study sheds new light on the specific radical chain reaction mechanisms of catalytic ozonation.
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Chemical Engineering and Processing-Process Intensification
·
2018
·
IF 2.826
Ding Chen,Peng-fei Feng,Fu-hua Wei
Fe-based metal-organic frameworks(Fe(III)-MOFs)were synthesized by Fe 2 (SO 4 ) 3 and trimesic acid using microwave-assisted ball milling method. The structure of the Fe(III)-MOFs was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Fourier transform infrared spectrometry (FTIR). The thermostability of the MOFs was analyzed by thermogravimetric analysis (TGA). Fe(III)-MOFs were added in aqueous solutions to remove organic dyes. The removal efficiencies of Orange II, CR and MB reached 95.9%, 98.7%, 95.7% respectively at 10℃ and reached 97.7%, 99.7%, 97.5% respectively at 35℃ in 300 min.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2018
·
IF 4.229
Ya Chu,Lin Gu,Hongmei Du,Konggang Qu,Yan Zhang,Jinsheng Zhao,Yu Xie
In this study, we synthesized a nitrogen rich compound (FPPHA) as the precursor of oxygen reduction reaction (ORR) catalysts, which was prepared based on 1,10-phenanthroline-5-amine and 2,2’-bipyridyl-5,5’-dialdehyde. The FPPHA-Fe complex was formed and be loaded on the carbon powder to form the FPPHA-Fe/C composite catalyst. The pyrolysis of the FPPHA-Fe/C composite was conducted at different temperatures, including 700 °C, 800 °C, and 900 °C, and the resultant pyrolyzed materials were designated to FPPHA-Fe/C-700, FPPHA-Fe/C-800, FPPHA-Fe/C-900, respectively. The physical characteristics of the catalysts were examined by powder X-ray diffraction (PXRD), Brunauer–Emmett–Teller analysis, X-ray photoelectron spectrometer (XPS) and scanning electron microscopy (SEM) etc. The ORR performance of the composite catalysts were evaluated by cyclic voltammetry (CV), linear sweep voltammetry (LSV), and rotating ring disk electrodes (RRDE) in an alkaline solution. The results suggested that the pyrolysis process has a positive effect on the ORR activity of the catalysts, and among the catalysts the Fe-FPPHA/C-800 had the most preferable performance, which reduces oxygen through a predominantly four electron pathway with an average electron transfer number of 3.86 and an average hydrogen peroxide yield of 6.7%.
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危险品化学品经营许可证（带存储）