JOURNAL OF NANOBIOTECHNOLOGY
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2023
·Vol. 21
·期 1
·1-14
·
IF 10.2
Yang Wen,Wang Ning,Yang Jin,Liu Chao,Ma Shuang,Wang Xiye,Li Wenzhen,Shen Meiling,Wu Qinjie,Gong Changyang
Background Photothermal therapy (PTT) is taken as a promising strategy for cancer therapy, however, its applicability is hampered by cellular thermoresistance of heat shock response and insufficient accumulation of photothermal transduction agents in the tumor region. In consideration of those limitations, a multifunctional “Golden Cicada” nanoplatform (MGCN) with efficient gene delivery ability and excellent photothermal effects is constructed, overcoming the thermoresistance of tumor cells and improving the accumulation of indocyanine green (ICG). Results Down-regulation of heat shock protein 70 (HSP70) makes tumor cells more susceptible to PTT, and a better therapeutic effect is achieved through such cascade augmented synergistic effects. MGCN has attractive features with prolonged circulation in blood, dual-targeting capability of CD44 and sialic acid (SA) receptors, and agile responsiveness of enzyme achieving size and charge double-variable transformation. It proves that, on the one hand, MGCN performs excellent capability for HSP70-shRNA delivery, resulting in breaking the cellular thermoresistance mechanism, on the other hand, ICG enriches in tumor site specifically and possesses a great thermal property to promoted PTT. Conclusions In short, MGCN breaks the protective mechanism of cellular heat stress response by downregulating the expression of HSP70 proteins and significantly augments synergistic effects of photothermal/gene therapy via cascade augmented synergistic effects.
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DOI
PubMed
高影响因子
JOM
·
2023
·Vol. 75
·期 12
·5321-5330
·
IF 2.6
Ma Yu,Zheng Yu,Xu Ming,Huang Shu,Yuan Guohui
Research on graphite as anode material for lithium-ion batteries (LIBs) has been carried out for a long time. Natural microcrystalline graphite (MG) with low cost and eco-friendly properties is a promising anode for LIBs. However, the tiny and irregular MG would cause serious side reactions with electrolytes and reduce the efficiency of energy storage. Here, the alkali fusion acid leaching method is employed for the purification of MG. After removing impurities, the purified MG is bound and wrapped by phenolic resin pyrolytic carbon to form secondary particles (PCG). Benefiting from the formation of secondary particles with a carbon shell, PCG exhibits a high specific capacity of 354.3 mAh/g and outstanding rate performance (82.7% capacity retention at 2 C). Meanwhile, outstanding cycling stability is demonstrated, with 92.7% capacity retention after 500 loops at 2 C. This research cleverly employs phenolic resin pyrolytic carbon to bind and wrap fragmented MG into secondary particles by a one-step method for high-performance LIBs anode. Such a “one stone two birds” strategy is cost-effective, environmentally friendly, and simple to operate, which is highly valuable for practical applications and provides a reference for the optimization of other graphite materials.
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2023
·Vol. 30
·期 8
·1-11
·
IF 2.8
Chen Fanfan,Xiao Yao,Yan Sitong,Fang Lin,Wang Zhifen,Liao Jianhe
Modifying natural rubber latex (NRL) and blending it with NRL can improve NRL performance and expand application fields. The performance of co-blended latex will change due to changes in non-rubber components during storage. Therefore, it is important to study the change of properties during the storage of co-blended latexes. In this paper, 30% methyl methacrylate grafted natural rubber (MG30) was synthesized by cumene hydroperoxide/ tetraethylenepentamine (CHPO/TEPA) initiating system, MG30 and NRL were mixed in different proportions to study the morphology and physical and mechanical properties, and the colloidal properties and emulsion properties of co-blended latexes were studied during storage. The results showed that the mechanical stability of NRL and co-blended latexes were high and the viscosity gradually increased during storage. The study of the vulcanization characteristics of the co-blended latexes films and the physical and mechanical properties of the vulcanized latex films showed that the vulcanization time of the co-blended films increased and the torque value increased in comparison to NRL. With the increase of MG30 content, the tensile strength and tear strength of the co-blended latexes vulcanized films showed a trend of increasing and then decreasing, and the co-blended film with 10% MG30 showed the best mechanical properties.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2023
·Vol. 58
·期 28
·11631-11646
·
IF 4.5
Li Peihang,Ran Hongshun,Pan Yaoyu,Xu Ziqiang,Chen Xueqin,Li Cao,Jiang Bingbing
Membrane separation is one of the most effective ways to remove organic dyes in wastewater. Rationally regulating the pore size of separation membranes would contribute to great performance. However, membranes with a uniform pore structure make it difficult to simultaneously realize high flux and excellent rejection ratio. Herein, functional composite nanoporous fiber membrane material with visible-light-driven self-cleaning performance was constructed by spinning hypercrosslinked polystyrene nanoparticles (HCPNPs) and TiO 2 -based catalysts into the electrospun membrane of polyvinylidene fluoride (PVDF). The composited fiber membrane with a hierarchical pore structure exhibits unique performances: excellent adsorption capacity for organic dyes, reaching 12 mg·g −1 (methylene blue), respectively, extraordinary high photocatalytic degradation rate (up to 99%) and gorgeous cycle degradation performance for MB (degradation rate is maintained at 95% after five cycles), and excellent comprehensive performance for the removal of extensive pollutant library including organic dye, and antibiotic pollutant. Therefore, coupled with facile and economical synthesis, we provide a novel idea for advanced membrane construction, which has the potential to be widely used for organic pollutants’ removal in sewage treatment. Graphical abstract
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高影响因子
Journal of Coatings Technology and Research
·
2023
·
IF 2.3
Meng Fangfei,Wang Wenjin,Yu Yijia,Xia Wenjuan,Wang Ling,Wu Zhaoqiang,Chen Hong
A simple and convenient strategy for fabricating superhydrophilic multifunctional antifogging coatings was developed by hydrolyzing triethoxysilyl-terminated poly( N -vinylpyrrolidone) (TRES-PVP) with tetraethyl orthosilicate (TEOS) under acidic conditions. These antifogging coatings can be easily obtained by coating TRES-PVP hydrolysates on substrates at room temperature and then curing by thermal treatment. The superhydrophilic transparent coatings exhibited excellent antifogging, self-cleaning and antifouling properties. Additionally, the coatings also have good adhesion against the cross-cut test and remain stable after exposure to the laboratory environment for five months or immersion in water at room temperature for 20 days. Therefore, the present TRES-PVP hydrolysate coatings are promising for practical multifunctional antifogging applications.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2023
·Vol. 34
·期 20
·1-15
·
IF 2.8
Xia Yifan,Lin Jingyu,Qian Jun,Liu Xiaoyun,Zuo Peiyuan,Zhuang Qixin
Improving the compatibility and dispersion between nanoparticles and polymers has become the key to enhance the dielectric properties. In addition, dielectric materials should also have excellent dielectric and thermal stability to meet the application under extreme conditions. Herein, we synthesized a core–shell structure BST@HBPI and BST@HBPI/PEI nanocomposite films. HBPI owns a chemical structure similar to polyetherimide (PEI), and the dipole moment of the polar group contained in it is small, so it can enhance the interface interaction between the nanoparticles and the matrix, hence effectively inhibiting the free charge, and reducing the leakage current in composite. The results show that the introduction of HBPI not only effectively improves the compatibility and dispersion of nanoparticles and polymer matrix, but also greatly enhances the dielectric properties and energy storage properties of nanocomposites. Under an electric field of 200 kV mm −1 , the minimum charge-discharge efficiency of BST@HBPI/PEI reaches 74.36%, which is 1.33 times of that for BST/PEI (55.97%), and the maximum discharge energy density reaches 5.01 J cm −3 , which is 1.28 times comparing to BST/PEI (3.89 J cm −3 ). Meanwhile, due to the preeminent electrothermal stability of nanoparticles and matrix, nanocomposites can maintain excellent dielectric properties at high temperatures. The dielectric constant of 10 vol% BST@HBPI/PEI (7.56 J cm −3 ) is 93.24% at 25 °C (8.113 J cm −3 ) while the dielectric loss at 200 °C (0.04287) is 114.29% when comparing to that at 25 °C (0.03751). This work provides a promising method for manufacturing dielectric materials that can work in extreme environments.
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高影响因子
Science China-Chemistry
·
2023
·
IF 9.6
Zhang Min,Li Zijun,Zhang Mengyang,Heng Hang,Xu Shiying,Wang Zhaoyin,Dai Zhihui
The content of biothiols in cells is highly associated with the occurrence and development of several diseases. However, due to their active chemical properties, thiol-contained molecules are normally volatile during the detection process, rendering precise analysis of intracellular biothiols challenging. In this study, 5,5′-dithiobis-(2-nitrobenzoic acid) (DTNB) is covalently modified on the surface of gold nanorods (AuNRs), constructing sensing substrates for in situ Raman imaging analysis of biothiols in cells. AuNRs are able to serve as ideal surface-enhanced Raman scattering substrates, and thus Raman signals of DTNB are greatly amplified by AuNRs. Meanwhile, the disulfide bond of DTNB can be broken by thiols, thereby releasing part of DTNB from the surface of AuNRs. As a result, three kinds of main biothiols are sensitively quantified with DTNB-modified AuNRs according to the variation of Raman signals, and DTNB-modified AuNRs exhibit far better analytical performance than a commercial probe. In addition, the sensing substrates can be readily delivered to cytoplasm with the transmembrane of AuNRs, and are capable of responding to biothiols in cells. Notably, the Raman approach is established by the breaking of chemical bonds rather than the aggregation of substrates, which is more inclined to analyze intracellular biothiols with a desirable spatial resolution. Therefore, fluctuation of biothiols in glioma cells is evidently observed via Raman imaging. Overall, this work provides an alternative strategy for designing Raman sensors to visualize active molecules in cells.
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高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
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2023
·Vol. 41
·期 12
·1889-1901
·
IF 4.3
Ma Jin-Liang,Liu Long-Long,Zhao Ren-Hai,Yuan Ding,Ning Xin
Reasonable construction of high activity and low cost non-noble metal oxygen reduction reaction (ORR) catalyst is of great importance for the wide application of zinc-air batteries (ZABs). Using bimetallic MOF as a precursor combined with electrospinning, high-temperature carbonization and electrodeposition, we successfully developed a porous carbon nanofiber (Co@Fe-CNFs-1000) with bimetallic active center as an efficient catalyst for ORR. The successful construction of this special core-shell structure directly explores the synergy between different active centers. The results showed that the synthesized Co@Fe-CNFs-1000 catalyst exhibited ORR performance comparable to that of Pt/C in 0.1 mol/L KOH electrolyte, high half-wave potential ( E 1/2 =0.81 V) and limiting current density ( J L =5.4 mA-cm −2 ). In addition, homemade liquid ZABs with Co@Fe-CNFs-1000 as the air cathode showed excellent power density (155.8 mW·cm −2 ), specific capacity (780.6 mAh·g Zn −1 ) and long-term stability (over 100 h at 2 mA·cm −2 ), surpassing even Pt/C-based batteries. In addition, the flexible solid-state ZABs assembled based on Co@Fe-CNFs-1000 demonstrates excellent flexibility and durability. This work provides a new idea for constructing ORR catalysts with high activity centers.
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高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2023
·
IF 2.5
Zhang Xiaodong,Zhang Guofeng
The materials conventionally used for electrocatalysis in electrocatalytic Fenton applications are unstable and perform poorly. Based on the fact that iron and copper are common electrocatalytically active metals, they can provide abundant electron transfer capacity to facilitate electron transfer in the reaction and further promote the electrical conductivity of nitrogen-doped doped carbon materials Here, FeCu alloy/N-doped carbon composites (FeCu/N-C) are prepared for the electrocatalytic degradation of naproxen (NPX). Characterization results reveal that FeCu/N-C has more active sites, a larger surface area, and faster charge transport than N-doped carbon composites (N-C). Meanwhile, the increased number of active sites, surface area, and electron transport result in excellent NPX electrocatalytic degradation efficiency. The FeCu/N-C composite exhibits higher degradation efficiency than N-C under optimal conditions. In addition, the degradation efficiency is sustained at around 100% after five cycles. A detailed analysis of the mechanism reveals that 1 O 2 and ·OH are the primary active species responsible for NPX degradation through bursting studies. A potential pathway for the NPX degradation is proposed. This study provides a new and feasible method for developing carbon-based electrocatalysts to expand their applications in the environmental field.
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高影响因子
CLAYS AND CLAY MINERALS
·
2023
·
IF 2.2
Weng Ming,Wang Xiuhua
Muscovite has been used increasingly as a substrate in flexible electronics and fillers in high-performance nanocomposites. Muscovite-based interfacial interactions play a crucial rule in material fabrication. Hansen solubility parameters (HSPs) have proven useful in characterizing molecular interactions within/between condensed phases. The present study aimed to determine the HSPs of raw muscovite (RM) and to investigate solvent dispersion mechanisms of RM. To achieve this, the solubilities of RM in 17 solvents were evaluated by dispersion tests, and the HSPs of RM were calculated as the center of the optimal solubility rotated-ellipsoid in HSP space, which included all good solvents, had the smallest number of outliers, and had the smallest volume. The resulting dispersion, polar, and hydrogen bonding components of RM were 18.301, 2.366, and 3.727 MPa 1/2 , respectively. By considering the HSPs and Kamlet-Taft's solvatochromic parameters of solvents, we concluded that the low polarity of RM is due to hindered K + /H + exchange on the RM surface, resulting from limited water/moisture contact. For solvent dispersion of RM, essential conditions include strong dispersion forces and weak polar forces, finely tuned to match the surface property of RM at a certain hydration level. The HSPs of RM determined from dispersion tests were restricted to predicting/characterizing RM-based interfacial phenomena in an environment with strictly controlled water/moisture content. The HSP calculation method proposed herein was applicable to any clay mineral.
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高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2023
·Vol. 52
·期 11
·7475-7483
·
IF 2.1
Sun Baorui,Zhang Minghui,Li Junjie,Li Zhe,Wen Mingli,Liu Zhi-Quan
Ag sintering technology for die-attach application in power semiconductors has garnered significant attention in recent years due to its excellent high-temperature service reliability. In this study, a highly reliable bonding joint was achieved using a specific Ag paste, resulting in shear strength of 37.63 MPa after pressureless bonding at 250°C for 10 min. However, a significant reduction in bonding strength was observed when using another set of Ag paste with better sintering performance. To investigate this anomalous phenomenon, we have performed a series of characterizations and proposed a corresponding bonding formation mechanism. The conclusions and inferences drawn from this study offer valuable theoretical support for the further application of Ag sintering, thereby promoting the advancement of this technology. Graphical Abstract
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2023
·Vol. 59
·期 2
·728-741
·
IF 4.5
Zhang Yongyue,Li Lin,Wang Hua,Wang Xiaowen,Pan Yanqiu,Wang Tonghua
In this work, in situ sol–gel strategy was used to introduce silica gel in polyacrylonitrile (PAN) membrane pores, by which the pore structure of organic solvent nanofiltration (OSN) membrane prepared with thermal crosslinking was maintained well. The chemical structure, microstructure and morphology changes of membrane during sol–gel and thermal crosslinking were systematically studied by FTIR, XPS, XRD and SEM. Benefitting from the introduction of silica gel, the fusion of membrane pore structure during thermal crosslinking was effectively inhibited by supporting the pore with silica gel. Therefore, the permeances of the thermally crosslinked membranes supported by in situ silica gel were greatly improved. Furthermore, the thermally crosslinked membrane showed excellent stability of OSN performance due to the generated ladder structure of membrane during thermal crosslinking. This work showed that in situ silica gel supporting is a promising strategy to stabilize the pore structure of PAN membrane during thermal crosslinking.
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高影响因子
危险品化学品经营许可证（带存储）