ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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2022
·Vol. 29
·期 29
·44504-44512
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IF 5.19
Chen Yanghan,Jin Qiuye,Tang Zhaomin
Drug residues, including various antibiotics, are being increasingly detected in aqueous environments. Ofloxacin (OFX) is one such antibiotic that is widely used in the treatment of several bacterial infections; however, chronic exposure to this antibiotic can have adverse impacts on human health. Hence, the identification of an effective OFX degradation method is essential. Thus, in this study, the degradation performance of OFX using potassium ferrate (Fe(VI)) under the influence of different initial concentrations, pH, temperature, and common ions in water was investigated. OFX degradation by Fe(VI) was directly proportional to the concentration of Fe(VI) and temperature and inversely proportional to the pH. Among the common ions in water, Fe 3+ and NH 4 + could significantly promote the degradation of OFX by Fe(IV), while humic acid (HA) significantly inhibited it. Under the conditions of [Fe(VI)]:[OFX] = 15:1, T = 25℃, and pH = 7.0, the removal efficiency of 8 μM OFX reached more than 90% in 4 min. Seven intermediates were identified by quadrupole time-of-flight tandem ultra-performance liquid chromatography mass spectrometry (Q-TOF LC/MS), and two possible pathways for the degradation of OFX by Fe(VI) were proposed. Overall, the results suggest that advanced oxidation technology using Fe(VI) is effective for treating wastewater containing OFX.
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SCIENCE OF THE TOTAL ENVIRONMENT
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2020
·
IF 6.551
Yi-meng Huang,Guang Li,Mingzhen Li,Jijie Yin,Na Meng,Di Zhang,Xiao-qiang Cao,Fan-ping Zhu,Ming Chen,Lin Li,Xian-jun Lyu
N-doped carbon materials have been proven to be effective catalysts for activating peroxymonosulfate (PMS). Marine algae biomass is rich in nitrogenous substances , which can reduce the cost of N-doping process and can obtain excellent N-doped catalysts cheaply and easily. In this study, kelp biomass was selected to prepare N-doped kelp biochar (KB) materials. The high defect degree, high specific surface area, and participation of graphite N make KB have excellent catalytic degradation ability. The KB degraded 40 mg/L ofloxacin (OFL) close to 100% within 60 min, applied with PMS. Through quenching experiments and electron paramagnetic resonance spectroscopy, the degradation process dominated by non-radical pathways was determined. At the same time, O 2 ·- and 1 O 2 were closely related, and a significant impact of quenching O 2 ·- on the reaction was observed. The non-radical approach made the system excellent performance over a wide pH range and in the presence of multiple anions. The experiments of reusability confirmed the stability of the material. Its catalytic performance was restored after low-temperature pyrolysis . This research supports the use of endogenous nitrogen in biomass. It provides more options for advanced oxidation process application and marine resource development.
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JOURNAL OF PHYSICAL CHEMISTRY B
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2014
·
IF 3.377
Wei Li,Xiongfei Chen,Yan Fu,Jinli Zhang,Wei Li
The specific interactions of Cu2+ with self-complementary DNA sequences involving d[G4C4(GC)2G4C4], d[(GC)10], and d[(AT)10], as well as the chiral recognition mechanism of ofloxacin enantiomers via the CuII-modulated DNAs, were investigated using characterizations of circular dichroism, gel electrophoresis, FT-IR spectroscopy, UV melting measurement, electron paramagnetic resonance, and HPLC. The CuII-coordinated GC-rich DNAs exhibit amplified enantioselectivity toward the S-enantiomer of ofloxacin. Especially in the case of d[G4C4(GC)2G4C4], ofloxacin enantiomers intercalate into the two adjacent guanine bases through the minor groove mediated by Cu2+, which leads to a more favorable binding between S-ofloxacin and DNA. The highest ee value of ofloxacin enantiomers in the permeate after being adsorbed by the CuII–DNA complex is obtained as 49.2% in the R-enantiomer at the [Cu2+]/[base] molar ratio of 0.25, while at the [Cu2+]/[base] molar ratio of 0.05 the highest ee value of ofloxacin enantiomers in the retentate reaches 26.3% in the S-enantiomer. This work illustrates a novel promising route to construct DNA-based chiral selectors toward certain drug enantiomers through the programmable enantioselective recognition on the basis of DNA chirality and the specific binding of transition metal ions.
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CHEMOSPHERE
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2020
·
IF 5.778
Guilong Peng,Chengdu Qi,Xiachao Wang,Linli Zhou,Qiang He,Wei Zhou,Lin Chen
Developing cost–effective metal/metal oxides for peroxymonosulfate (PMS) activation remains a key issue in the sulfate radical based advanced oxidation process . In this work, electroplating sludge (ES), a transition metal–rich byproduct, was anaerobic calcined and characterized. Then, calcined electroplating sludge (CES) was applied as PMS activator for degradation of ofloxacin (OFL) and CES/PMS system exhibited a nearly 90% of OFL removal in 60 min. In addition, effect of CES, PMS , the initial pH and water constituents (chloride, bicarbonate , natural organic matter (NOM) and water backgrounds) on OFL degradation were systematically studied. Moreover, radical quenching tests and electron spin–resonance spectroscopy studies manifested that both SO 4 – and HO were the ruling reactive oxygen species . X–ray photoelectron spectroscopy results of the fresh and used CES demonstrated that the PMS activation mainly occur in the transformation from Fe 3+ (Cu 2+ ) to Fe 2+ (Cu + ). Furthermore, liquid chromatography coupled with ion trap time–of–flight mass spectrometry was used to illustrate the possible degradation pathway of OFL. Moreover, CES showed excellent stability and reusability during reaction. This work points out a new way for value–added reuse for ES as a cost–efficient activator of PMS for organic contaminant removal.
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Journal of Environmental Chemical Engineering
·
2024
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IF 7.4
Jun Chen,Zongsheng Zhan,Zhaoming Chen,Yutong Wang,Xue Li,Mingxia Du,Dawei Teng,Dong Lv,Chunnan Da,Mengqiu Xu
An iron-nitrogen co-doped cattail carbon (Fe-N@CC) was prepared by chemical modification using potassium ferrate, urea, and biomass of cattail. The specific surface area of Fe-N@CC was 552.13 m 2 /g, with abundant functional groups on the Fe-N@CC surface. The synergistic manner with physical field strength of ultrasound (US) and chemical modification of Fe-N@CC was applied in the activation of persulphate (PS). The US/Fe-N@CC/PS system achieved the highest degradation efficiency compared to other systems, with 99.72% ofloxacin (OFX) degradation rate within 30 min. The results indicated that the non-radical pathway dominated by singlet oxygen ( 1 O 2 ) played an important role in the US/Fe-N@CC/PS system for OFX degradation. The sp 2 -hybrid carbon of C-N, pyridinic N, and α-Fe 0 as the active site in Fe-N@CC, while effects of US such as strong turbulence, liquid flow contribute to enhanced mass transfer, cavitation effects, and locally higher pressures and temperatures, these synergistic effects promoted electron transfer and production of reactive oxygen species during OFX degradation in US/Fe-N@CC/PS system. The ten intermediates and four degradation pathways of OFX were determined by liquid chromatography-mass spectrometry and density functional theory calculations. The toxicity of most intermediates was lower than that of the parent OFX as determined by the toxicity analysis software in the US/Fe-N@CC/PS system. The new approach to synergistically activating PS by US physical field strength and with chemical modification using Fe-N@CC had provided an efficient method for the treatment of antibiotics.
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Discover Materials
·
2026
·
IF 5.8
Shah Roman,Ahmad Wisal,Khan Dilaram,Shah Syed Izaz Ali,Anwar Muhammad,Khan Sidra,Khan Javed Ali
In this study, phosphorus-doped graphene oxide nanosheets (P-GO NSs) were prepared using modified Hummer’s method. The as-prepared sample was evaluated for the degradation of ofloxacin (OFL) and hydrogen (H 2 ) production. The structural, morphological, optical, and electronic properties of the P-GO NSs were characterized using UV-DRS, FTIR, SEM, XPS, HR-TEM and BET analysis. Phosphorus doping significantly improved the physicochemical properties of graphene oxide (GO) as evident by higher surface area of P-GO NSs (423 m² g⁻¹) than that of pristine GO (160 m² g⁻¹). Additionally, phosphorus doping narrowed the bandgap of GO from 3.9 to 3.3 eV. The P-GO NPs exhibited remarkable photocatalytic performance towards OFL degradation. The % degradation of OFL was observed to be 99.2% for P-GO and 65.0% for GO under UV light irradiation. The degradation experiments were performed under the conditions of: [OFL] 0 = 10 mg/L, [P-GO/GO] 0 = 0.5 g/L, pH = 7 and reaction time = 120 min. The GC-MS was used to identify the degradation products (DPs) of OFL and their ecotoxicity was predicated using the ECOSAR software. Furthermore, the P-GO NPs demonstrated efficient photocatalytic H 2 production under UV light irradiation, reaching H 2 production rate of 410 µmol h -1 g -1 in the presence of Pt (0.2 wt%) as a co-catalyst. Overall, phosphorus doping effectively modified the optoelectronic and structural characteristics of GO, improving charge carrier separation and providing more active sites which led to enhanced performance for removal of organic pollutants and sustainable H 2 production. Graphical abstract
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2020
·Vol. 412
·期 19
·4555-4563
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IF 3.637
Huang Yukun,Wang Chong,Huo Qiuyu,Song Yaning,Du Gang,Wang Lijun,Yang Xiao,Chen Xianggui
A novel sensitive, competitive, and time-resolved luminescence sensor for the detection of ofloxacin (OFL) was developed in this study. The sensor used OFL-specific aptamer as a recognition molecule and rolling circle amplification (RCA) as a signal amplification tool. In this way, the time-resolved luminescence can not only avoid background noise from sample, but also provide robust luminescence for detection. Besides, the separation and enrichment of target veterinary drug can be conducted assisted by magnetic treatment. Under optimal conditions, the logarithmic correlation between the concentration of OFL and the luminescence intensity was found to be linear in the range of 5 × 10 −11 –5 × 10 −8 mol L −1 ( R 2 = 0.9988), with a detection limit (LOD) of 32.1 pmol L −1 . Furthermore, this method was applied to the determination of OFL in chicken and pork samples, exhibiting good recovery (72.5–100%) and repeatability (RSD < 10.0%). These results confirm that this novel established method has good application potential for the detection of OFL in food samples.
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SCIENCE OF THE TOTAL ENVIRONMENT
·
2018
·
IF 4.61
Yang Yu,Fei Huang,Yide He,Xiyang Liu,Chenjing Song,Yanhua Xu,Yongjun Zhang
In this study, heterogeneous Fenton-like degradation of ofloxacin (OFX) was investigated by sludge derived carbon (SC). The effects of SC catalyst, temperature and pH on the efficiency of ofloxacin degradation were investigated. SC treated with sulfuric acid (SC-H 2 SO 4 ) performed high catalytic activity , indicating that sulfate group produced low pH of the surface and was beneficial for heterogeneous Fenton-like degradation. The removal of ofloxacin and TOC was 91.5% and 62.3%, respectively, after 180 min adsorption and 540 min oxidation, at pH 6 and a dosage of 138 mg L −1 H 2 O 2 . It was found that OFX conversion increased with the decrease of pH and OFX was degraded under the wide range of pH (3–6) by SC-H 2 SO 4 . These promising results clearly demonstrate the potential of the heterogeneous Fenton-like process for the effective degradation of ofloxacin by SC-H 2 SO 4 . Based on intermediated products identified by gas chromatography–mass spectrometry, a possible OFX oxidation pathway in Fenton-like reaction was proposed.
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iScience
·
2025
·
IF 4.1
Li Yanhong,Zhao Zikang,Zhao Yao,Tang Shen,Zhang Lihao,Zhang Jie,Peng Yuqing
The overuse of antibiotics poses critical threats to environmental and human health. This study developed a constructed wetland-microbial fuel cell (CW-MFC) system integrated with pre-acclimated Shewanella oneidensis MR-1 to enhance ofloxacin (OFL) removal from wastewater. The CW-MFC demonstrated exceptional removal efficiency (>96%) for OFL across tested concentration gradients, significantly outperforming conventional constructed wetlands (CW) in both antibiotic elimination and conventional pollutant reduction. Microbial community analysis revealed that S. oneidensis MR-1 inoculation enhanced microbial diversity under OFL stress while promoting enrichment of electroactive Firmicutes phylum members compared to non-inoculated systems. The synergistic integration of bioelectrochemical processes and microbial consortia modification in CW-MFCs effectively addressed antibiotic contamination challenges. These findings establish CW-MFC technology combined with electroactive bacteria acclimation as a sustainable solution for pharmaceutical wastewater treatment, providing critical insights for optimizing antibiotic removal strategies in engineered ecosystems.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Hao Li,Manling Zhang,Yufeng Jiang,Yi Liu,Wenjun Duan,Di Lang,Wei Du,Zhaofeng Chang,Peng Zhang,Bo Pan
s Biochar exhibited excellent performance in activating persulfate (PS) for the degradation of organic contaminants. However, the role of endogenous metals in the activation of PS needs to be clarified, which will hinder the understanding of the PS activation mechanism by biochar and the design of efficient biochar for PS activation. In this study, biochars were prepared at different temperatures using cellulose, and trace amounts of Fe (0.069 %) and Mn (0.056 %) were incorporated separately or together into biochar to mimic the endogenous metals whose concentrations were consistent with the ones in local corn stalks. Our results demonstrated that a trace amount of Fe could greatly enhance the removal of ofloxacin (OFL) in the C1000-Fe system. Removing metals from biochar via acid-washing did not significantly impact the removal efficiency of OFL. The Raman analysis showed that Fe could increase the defect structures in C1000-Fe, which were converted during the cycling experiments, indicating they participated in the activation of PS. ROS capturing and quenching experiments confirmed that the increased defect structures via Fe in C1000-Fe facilitate the activation of PS to generate superoxide anions (O 2 •− ) and then convert them into singlet oxygen ( 1 O 2 ) for OFL degradation. Our results highlighted that a trace amount of Fe in biochar enhanced its activation of PS for degradation of OFL via altering the carbon structure, not itself as the activation site, which will benefit understanding the role of endogenous metals in the activation of PS.
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Surfaces and Interfaces
·
2024
·
IF 5.7
Yiqiong Yang,Jiaying Ye,Yixuan Zhai,Bingbing Yang,Mingyao Yin,Yi Xu,Jinfeng Wang,Xiaodong Zhang
In this study, we successfully synthesized ZIF-67 material on three-dimensional (3D) nickel foam (NF) substrate by co-precipitation method, and then fixed CoS x on NF by hydrothermal vulcanization method to form CoS x /NF. The optimized CoS x /NF can effectively activate peroxymonosulfate (PMS) and improve the degradation efficiency of ofloxacin (OFL). The effects of PMS dosage, reaction temperature, initial pH and co-existing ions on the degradation effect of OFL were investigated in detail. CoS x /NF (1 piece 2 × 2 cm) and PMS (1 mM) in an aqueous solution (pH = 7) degraded 85 % of OFL (20.0 mg/L) within 45 min. This favorable degradation performance is mainly attributed to the enhanced electron transfer capability introduced by the bimetallic material. In addition, CoS x /NF still maintained high degradation effect and stable structure after 5 cycles. Quenching experiments further revealed that radicals •OH and 1 O 2 play a major role in degrading OFL. In addition, the degradation pathway, ecotoxicity evaluation and degradation mechanism of OFL were comprehensively investigated. In summary, the CoS x /NF catalyst proved to be a highly efficient, stable and recyclable heterogeneous composite, and opened up the possibility of using Metal-organic framework (MOF) derivatives in fields such as wastewater treatment .
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Materials Science & Engineering C-Materials for Biological Applications
·
2016
·
IF 3.42
Jing Li,Sanming Li,Zhonggui He
In the present work, molecular imprinting silica xerogel (MISX) with selective recognition function aiming to regulate drug therapy was synthesized using biomimetic method with poly(ethyleneimine)s (PEIs) as the polymer template and levorotatory ofloxacin (LOFL) as recognition template. Ultraviolet spectroscopy wavelength scanning was used to test the removal process of LOFL, and characteristics of selective loading ofloxacin (OFL) into MISX were investigated using Fourier transform infrared spectroscopy (FT-IR) and differential scanning calorimetry (DSC). Molecular recognition functionality of MISX was intensively studied, including OFL loading and release. The results suggested that MISX possessed ability to recognize and selectively adsorb LOFL into MISX in OFL aqueous solution. Amorphous phase of adsorbed molecules contributed to molecular recognition because amorphous state increased the stability of LOFL that were selectively adsorbed into MISX, which induced stronger hydrogen bonding formed between LOFL and MISX so as to improve LOFL recognition ability. In vitro release revealed that OFL-MISX tablet initially released LOFL and later gradually OFL into dissolution medium. Thus conversion of drug release with different pharmacological activity had special value in delivering systems.
研究领域:
药剂学
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药物化学
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纳米医学
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生物材料
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分子识别
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药物递送系统
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危险品化学品经营许可证（带存储）