TALANTA
·
2011
·
IF 3.722
Qiong-Wei Yu,Qiao Ma,Yu-Qi Feng
The silica nanoparticle (SiO 2 NP)-deposited capillary fabricated by liquid phase deposition (LPD) was bonded by 3-(triethoxysilyl) propyl methacrylate and then modified with poly(N-isopropylacrylamide) (PNIPAAm) by polymerization. The resulting PNIPAAm modified SiO 2 NP-deposited capillary was applied to in-tube solid-phase microextraction coupled to high-performance liquid chromatography (in-tube SPME–HPLC). To investigate the extraction performance of the prepared capillary, diethylstilbestrol (DES) with moderate polarity was selected as the model analyte. Results demonstrate that PNIPAAm modified SiO 2 NP-deposited capillary exhibited obvious temperature responsive character. Finally, the PNIPAAm modified SiO 2 NP-deposited capillary was applied to the analysis of three synthetical estrogens from milk samples. The detection limit of the method was found to be in the range 1.2–2.2 ng/g, and recovery was 71.7–98.9% with relative standard deviations in the range of 2.8–12.6%.
研究领域:
分析化学
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环境科学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Zhibin Zhang,Yajun Wang,Zheng Li,Hiroshi Fu,Jianying Huang,Zhiwei Xu,Yuekun Lai,Xiaoming Qian,Songnan Zhang
As an effective way to obtain freshwater resources, atmospheric water harvesting (AWH) technology has been a wide concern of researchers. Therefore, hydrogels gradually become key materials for atmospheric water harvesters due to their high specific surface area and three-dimensional porous structure. Here, we construct a core–shell hydrogel-based atmospheric water harvesting material consisting of a shell sodium polyacrylate (PAAS) hydrogel with an open pore structure and a core thermosensitive poly N-isopropylacrylamide (PNIPAAm) hydrogel with a large pore size. Theoretically, the mutual synergistic hygroscopic effect between the core layer and the shell layer accelerates the capture, transport, and storage of moisture to achieve continuous and high-capacity moisture adsorption. Simultaneously, the integration of polydopamine (PDA) with the hydrogel realizes solar-driven photothermal evaporation. Therefore, the prepared core–shell hydrogel material possesses great advantages in water adsorption capacity and water desorption capacity with an adsorption of 2.76 g g–1 (90% RH) and a desorption of 1.42 kg m–2 h–1. Additionally, the core–shell structure hydrogel collects 1.31 g g–1 day–1 of fresh water in outdoor experiments, which verifies that this core–shell hydrogel with integrated photothermal properties can capture moisture in a wide range of humidity without any external energy consumption, can further sustainably obtain fresh water in remote water-shortage areas.
研究领域:
材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
Coatings
·
2018
·Vol. 8
·期 2
·68
·
IF 2.35
Jia Li,Boxiang Wang,Jie Lin,Dehong Cheng,Yanhua Lu
Multifunctional mulberry silk fabrics with excellent temperature- and pH-sensitivity, antibacterial properties and permeability are successfully prepared by surface modification with PNIPAAm/chitosan/poly(ethylene oxide) nanofibers. The nanofibers deposited on the surface of mulberry silk fabric are produced by the electrospinning technique. The surface properties of mulberry silk fabrics were changed by coating process and glutaraldehyde vapor cross-linking technology. The PNIPAAm/chitosan/PEO nanofibers have good apparent morphology and uniform fiber diameter. The contact angle of modified mulberry silk obviously increases with the increasing temperature. The bacterial reduction rates of modification of mulberry silk againstE. coliandS. aureusall reach above 80%. Permeability test results show that it can largely improve the poor permeability of coated fabric by intelligent nanofiber modification technology. The air permeability of temperature- and pH-sensitivity mulberry silk fabric modified with PNIPAAm/chitosan/PEO nanofibers, which has reached about 5.1 × 102L/m2/s, is higher than that of the silk fabric coated with PNIPAAm/chitosan/PEO solution that reached 1.5 × 102L/m2/s. The nanofibers coated with mulberry silk fabrics show outstanding temperature- and pH-sensitivity, antibacterial properties and permeability, and may be a potential application in medical care, intelligent materials and textiles.Keywords:chitosan;poly(N-isopropyl acrylamide);mulberry silk;electrospinning;antibacterial activity;thermosensitive behavior
研究领域:
材料科学
·
纺织工程
·
生物医学工程
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产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 67
·62186-62192
·
IF 3.289
Jianjian Cai,Shouyong Zhou,Yijiang Zhao,Ailian Xue,Yan Zhang,Meisheng Li,Weihong Xing
The hydrophilicity of a thermo-responsive PVDF/palygorskite-g-PNIPAAM hybrid ultrafiltration membrane was enhanced via surface segregation induced by coagulation bath temperature (CBT). The N1s content of the hybrid ultrafiltration membranes prepared at 5 and 20 °C is 1.77% and 1.02%, respectively while that of the membrane prepared at 40 °C is just 0.73%. This indicated that the PNIPAAM chains could be dragged to the membrane surfaces or pores via surface segregation induced by temperature. This resulted in higher hydrophilicity and permeability as well as thermo-responsiveness for membranes prepared at lower temperatures. The initial water contact angle of the PVDF/palygorskite-g-PNIPAAM hybrid ultrafiltration membrane prepared at 5 and 20 °C is 75.2° and 75°, respectively, which is about 6° lower than the one prepared at 40 °C. A higher pure water flux (PWF) of about 366 L m−2 h−1 at 40 °C was obtained for the hybrid membrane prepared at 5 °C while the one prepared at 40 °C only reached 274 L m−2 h−1. Meanwhile, membranes prepared at low temperature exhibited fewer macrovoids, lower membrane thickness and larger elongation.
研究领域:
材料科学
·
环境工程
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产品关联
DOI
高影响因子
Advanced Healthcare Materials
·
2022
·Vol. 11
·期 15
·2200648
·
IF 11.092
Weiyan Sun,Jiahui Zhang,Yechi Qin,Hai Tang,Yi Chen,Weikang Lin,Yunlang She,Kunxi Zhang,Jingbo Yin,Chang Chen
Cell spheroids are a promising bioprinting building block that can mimic several physiological conditions in embryonic development. However, it remains challenging to efficiently prepare cell-spheroid-based bioink (Sph-bioink) with favorable printability and spheroid fusion ability. In this work, a poly( N -isopropylacrylamide) (PNIPAAm)-based porous hydrogel is developed as an “all-in-one” platform for Sph-bioink preparation. On the one hand, the nonadhesive porous structure in hydrogels is an effective tool for fabricating adipose-derived stem cell (ASC) spheroids in high yield, and the hydrogel itself also serves as a “carrier” for conveniently transferring cell spheroids to the bioprinter. On the other hand, the integration of redox/thermo-responsiveness allows the hydrogel to shift from a solid spheroid-making tool to an extrudable bioprinting medium that is sensitive to temperature. These features enabled a simple procedure for preparing Sph-bioink, in which the cell spheroids were densely packed to retain fusion capability. The present study also demonstrates that ASC spheroids formed in hydrogels have good biological preservation and superior chondrogenic differentiation, and verified the feasibility of using Sph-bioink to build custom-shaped mature cartilage. In conclusion, this strategy provides a simple, efficient, and standardized approach for Sph-bioink preparation, making it possible to produce tissue-engineered constructs with accelerated maturation and functionalization.
研究领域:
生物打印
·
组织工程
·
干细胞研究
·
材料科学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jiaojiao Su,Yaning Zhang,Mingli Yue,Jian Liu
Cell chirality is a complex phenomenon that imparts unique properties. The creation of biomimetic artificial cells chirality is a rapidly evolving research topic that has had a profound impact in multiple fields, including materials science, catalysis, biotechnology, and biomedicine. Herein, we report a simple method that combines L- or D-penicillamine (L/D-Pen) with proteinosomes on the surface of gold nanoparticles to afford nanoparticle hybrid microcapsules. Encapsulation of the enzyme in the microcapsule enables a chiral recognition effect on the membrane surface, thereby affording control over the enantioselective catalytic reaction of the d -glucose (D-Glu) substrate loaded inside the hybrid microcapsule. The adsorption energy of D-Glu and D-Pen (−0.095) calculated by MS is less than that of D-Glu and L-Pen (−0.064). Thus enantiomeric selective recognition is a stronger interaction force than adsorption for the same configuration. These findings highlight the development of biomimetic chiral microcompartments, and provide a platform for driving cellular chirality in various organisms.
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Hongxu Liu,Junhao Xie,Jingxuan Zhao,Ruijia Wang,Yuchao Qi,Shulin Sun
Traditional water treatment membranes always face the problem of membrane contamination in the practical application. Those contaminants deposited on the membrane surface and inside the membrane pores make the filtration process more difficult. Herein, the temperature and photo sensitive nanocomposite membranes with superior wasterwater separation and light-cleaning capabilities were prepared by a non-solvent induced phase separation method, which combined the thermo-responsive property of poly(N-isopropylacrylamide) (PNIPAAm) grafted polyvinylidene fluoride (PVDF) and the high photothermal conversion character of core–shell structured BN@PDA-Ag nanosheets. The membranes can be heated to high temperature within a short period of light exposure due to the fast photothermal conversion capability of Ag and the excellent thermal conductivity of boron nitride (BN). The increase in temperature led to the contraction of PNIPAAm chains and bigger pore size. The microstructure, filtration, and cleaning performance of the nanocomposite membranes can be controlled by illumination, which allowed PVDF-g-PNIPAAm/BN@PDA-Ag membranes to achieve the effect of first interception and then cleaning. The membranes showed retention rates of 82, 99 and 95 % for BSA, oil–water emulsions and various dyes with flux recovery rates of > 90 % after light cleaning. This work provides a simpler, more efficient membrane cleaning strategy with superior potential for dealing with membrane contamination.
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DOI
高影响因子
Journal of Materials Chemistry B
·
2014
·Vol. 3
·期 4
·629-634
·
IF 0
Xinhong Xiong,Zhaoqiang Wu,Jingjing Pan,Lulu Xue,Yajun Xu,Hong Chen
Tailoring the surface properties of poly(dimethylsiloxane) (PDMS) is essential for the advancement of its applications. However, the modification process is usually complicated and limited due to the chemical inertness of the surfaces of PDMS. Here, we report for the first time, a facile and versatile method for the functional surface modification of PDMS via visible light-induced grafting polymerization at room temperature. This modification is readily achieved in two steps: (1) covalently integrating alkyl bromine into the PDMS networks using a simple mixing procedure and (2) visible light-induced surface grafting polymerization using Mn2(CO)10. We have demonstrated that the PDMS surface can be functionalized with a wide variety of polymers via covalent grafting, such as poly(trifluoroethyl methacrylate) (PTFEMA), poly(N-isopropylacrylamide) (PNIPAAm), poly(acrylic acid) (PAA) and poly(vinyl acetate) (PVAc). As an example, after the grafted PVAc was transformed into its hydrophilic analogue poly(vinyl alcohol) (PVA), anti-biofouling functionalization of PDMS was obtained. The anti-biofouling properties of the functionalized PDMS were demonstrated using cell adhesion and bacterial adhesion tests. Moreover, the grafting kinetics of PVAc showed that this process was fast and efficient.
研究领域:
材料科学
·
聚合物化学
·
表面工程
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DOI
PubMed
MACROMOLECULES
·
2022
·
IF 6.057
Huaisong Yong,Jens-Uwe Sommer
Despite the fact that the observation of cononsolvency was reported as early as four decades ago, its phase-transition mechanism is still under debate. In this work, we provided a comprehensive study of the phase behaviors of poly(N-isopropylacrylamide) (PNiPAAm) in sulfoxide or sulfone aqueous solutions. We observed a sharp collapse transition of PNiPAAm brushes in sulfoxide but not in sulfone aqueous solutions by equilibrium measurements of in situ spectroscopic ellipsometry. We found that the hydrogen-bond formation between sulfoxide oxygens and amide hydrogens of the polymer chains plays a critical role in regulating the cononsolvency of PNiPAAm. We have extended the concept of preferential adsorption by taking into account hydrophobic interactions between cosolvent molecules, which are adsorbed on the polymer by hydrogen bonds. This can explain the experimental observations of PNiPAAm brushes in these solvent mixtures and sheds light on understanding the phase behaviors of polymer solutions where hydrogen bonds and hydrophobic interaction play a critical role. Our results can also be of interest for the liquid–liquid phase separation in the living cell where the condensation of proteins bound to large biomacromolecules plays an essential role.
研究领域:
高分子科学
·
物理化学
·
生物物理学
·
材料科学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Jingxuan Zhao,Ying Xue,Yue Wu,Xiaonan Hao,Shulin Sun,Huiliang Zhang
This study presents an innovative approach to membrane fabrication by integrating electrospinning with surface modification techniques to develop a novel dual-layer protective membrane system. The key innovation lies in the incorporation of photothermally responsive nanocomposites, enabling multifunctional membrane performance. The primary layer is a PVDF-PNIPAAm thermoresponsive matrix synthesized by radical polymerization, integrated with BN@PDA-Ag nanosheets. This design combines Ag nanoparticles’ photothermal conversion and BN’s thermal conductivity to regulate pore size via PNIPAAm chain conformational changes induced by temperature. The secondary layer, comprising CS@CNT and PVDF, significantly enhances membrane hydrophilicity and antifouling properties through chitosan’s hydrophilic groups and chelating capabilities. The membrane demonstrates self-cleaning, adaptive filtration, antifouling and high flux, representing a significant advancement in smart membrane technology for water treatment applications.
研究领域:
材料科学
·
环境工程
·
纳米技术
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产品关联
DOI
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2024
·Vol. 22
·期 1
·1-14
·
IF 10.6
Liu Xueyan,Hu Tingting,Jia Yijiang,Yang Shuqing,Yang Yu,Cui Zhuolin,Wang Tao,Liang Ruizheng,Tan Chaoliang,Wang Yuji
The rapid proliferation of tumors is highly dependent on the nutrition supply of blood vessels. Cutting off the nutrient supply to tumors is an effective strategy for cancer treatment, known as starvation therapy. Although various hydrogel-based biomaterials have been developed for starvation therapy through glucose consumption or intravascular embolization, the limitations of single-mode starvation therapy hinder their therapeutic effects. Herein, we propose a dual-function nutrition deprivation strategy that can block the nutrients delivery through extravascular gelation shrinkage and inhibit neovascularization through angiogenesis inhibitors based on a novel NIR-responsive nanocomposite hydrogel. CuS nanodots-modified MgAl-LDH nanosheets loaded with angiogenesis inhibitor (sorafenib, SOR) are incorporated into the poly(n-isopropylacrylamide) (PNIPAAm) hydrogel by radical polymerization to obtain the composite hydrogel (SOR@LDH-CuS/P). The SOR@LDH-CuS/P hydrogel can deliver hydrophobic SOR with a NIR-responsive release behavior, which could decrease the tumor vascular density and accelerate cancer cells apoptosis. Moreover, the SOR@LDH-CuS/P hydrogel exhibits higher (3.5 times) compressive strength than that of the PNIPAAm, which could squeeze blood vessels through extravascular gelation shrinkage. In vitro and in vivo assays demonstrate that the interruption of nutrient supply by gelation shrinkage and the prevention of angiogenesis by SOR is a promising strategy to inhibit tumor growth for multimode starvation therapy.
研究领域:
生物医学工程
·
癌症治疗
·
材料科学
·
药学
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产品关联
DOI
PubMed
高影响因子
Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
·
2022
·
IF 3.549
Jiachang Feng,Jianpeng Dou,Wenfu Wu
The competitive inhibition of aflatoxigenic fungi by non-aflatoxigenic Aspergillus flavus has proved to be an effective method to prevent and control peanut aflatoxin contamination, and most of the currently used inoculum carriers are grains. In this study, the reliability and efficiency of replacing grain kernels with novel chitosan-coated alginate-poly(N-isopropylacrylamide) (PNIPAAm) beads impregnated with biochar (CSACB) were evaluated. Characterisation of the beads was performed by SEM, thermogravimetry analysis (TGA), and swelling properties analyses. The optimised CSACB beads had good physical stability, shelf life, and entrapment efficiency. In addition, the water-holding capacity and porous structure were excellent, as the biochar provided a beneficial microenvironment for the attachment and microbial growth of the biocontrol fungus. The effect of reducing aflatoxin in peanuts was verified experimentally. Collectively, the novel CSACB beads are suitable carriers of non-aflatoxigenic A. flavus for the biocontrol of peanut aflatoxin.
研究领域:
农业科学
·
食品科学
·
生物技术
·
微生物学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）