Nanoscale
·
2023
·Vol. 15
·期 45
·18395-18406
·
IF 6.7
Kun Wang,Liyuan Wang,Jinrui Huang,Ye Chen,Xupo Liu,Tianfang Yang,Gangya Wei,Shuyan Gao
The introduction of transition bimetallic alloys can effectively improve oxygen reduction reaction (ORR) activity. However, the alloy particles are inclined to dissolve under harsher conditions, resulting in a serious decrease in catalytic activity and stability. Herein, an efficient ORR catalyst, FeCo alloy nanoparticles (NPs) encapsulated in N,S co-doped carbon nanotubes (FeCo10-NSCNTs), was developed through a self-catalyzed growth strategy. Due to the delicate structural design, the N,S co-doped structure can effectively improve the ORR performance by modulating the electronic properties and surface polarity of the carbon substrate, and the randomly connected carbon nanotube structure with large specific surface area can further enhance the adsorption and dissociation of gas molecules, accelerating the kinetics of gas participation in the reaction. Carbon-encapsulated FeCo alloys are beneficial for improving catalytic activity and durability. The FeCo10-NSCNTs displayed excellent ORR activity with a half-wave potential of E1/2 = 0.84 V and robust stability of 13 k cycles. More impressively, the assembled liquid-state Zn–air battery (ZAB) with FeCo10-NSCNTs as the air-electrode delivers an output power density of 146.68 mW cm−2 along with excellent operation durability. The assembled all-solid ZAB has good cyclic stability under 0–180° bending conditions. The synthesized N,S co-doping, carbon nanotubes and FeCo alloys provide important guidance for the construction of cheap non-noble metal–carbon hybrid nanomaterials.
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高影响因子
MOLECULES
·
2023
·Vol. 28
·期 15
·5885
·
IF 4.6
Haiyan Zhao,Li Chen,Nan Ni,Yang Lv,Hezhen Wang,Jia Zhang,Zhiwen Li,Yu Liu,Yubo Geng,Yan Xie,Li Wang
There is an urgent need to design and synthesize non-noble metal electrocatalysts (NNMEs) for the replacement of platinum-based electrocatalysts to enhance the sluggish oxygen reduction reaction (ORR) for Zn–air batteries and fuel cells. Herein, Fe-N,S-C materials were fabricated through two steps: first, reprecipitating hemin by adjusting the pH and, then, decorating it with melamine and cysteine in the presence of Zn2+. The resulting Fe-N,S-C-950 (Zn) was prepared after pyrolysis at 950 °C. Using this method, abundant iron-based active species with good dispersion were obtained. The fabrication of more micropores in Fe-N,S-C-950 (Zn) plays a positive role in the improvement of ORR activity. On comparison, Fe-N,S-C-950 (Zn) outperforms Fe-N,S-C-950 and Fe-N-C-950 (Zn) with respect to the ORR due to its larger specific surface area, porous structure, multiple iron-based active sites and N- and S-doped C. Fe-N,S-C-950 (Zn) achieves outstanding ORR performances, including a half-wave potential (E1/2) of 0.844 V and 0.715 V versus a reversible hydrogen electrode (RHE) in 0.1 M KOH and 0.1 M HClO4solution, respectively. In addition, Fe-N,S-C-950 (Zn) shows an outstanding Zn–air battery performance with an open-circuit voltage (OCV) of 1.450 V and a peak power density of 121.9 mW cm−2, which is higher than that of 20 wt% Pt/C. As a result, the as-prepared electrocatalyst in this work shows the development of the Zn-assisted strategy combined with the assembly of porphyrins as NNMEs for the enhancement of the ORR in both alkaline and acidic solutions.Keywords:FeNSC;hemin;oxygen reduction reaction;Zn–air battery
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MOLECULES
·
2019
·Vol. 24
·期 7
·1203
·
IF 3.06
Mengying Wei,Yuanyuan Liu,Zifeng Pi,Shizhe Li,Mingxin Hu,Yang He,Kexin Yue,Tianshu Liu,Zhiqiang Liu,Fengrui Song,Zhongying Liu
Lignans fromSchisandra chinensis(Turcz.) Baill can ameliorate cognitive impairment in animals with Alzheimer’s disease (AD). However, the metabolism of absorbed ingredients and the potential targets of the lignans fromS. chinensisin animals with AD have not been systematically investigated. Therefore, for the first time, we performed an in-vivo ingredient analysis and implemented a target-network pharmacology strategy to assess the effects of lignans fromS. chinensisin rats with AD. Ten absorbed prototype constituents and 39 metabolites were identified or tentatively characterized in the plasma of dosed rats with AD using ultra high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Based on the results of analysis of the effective constituents in vivo, the potential therapeutic mechanism of the effective constituents in the rats with AD was investigated using a target-network pharmacology approach and independent experimental validation. The results showed that the treatment effects of lignans fromS. chinensison cognitive impairment might involve the regulation of amyloid precursor protein metabolism, neurofibrillary tangles, neurotransmitter metabolism, inflammatory response, and antioxidant system. Overall, we identified the effective components of lignans inS. chinensisthat can improve the cognitive impairment induced by AD and proposed potential therapeutic metabolic pathways. The results might serve as the basis for a fundamental strategy to explore effective therapeutic drugs to treat AD.Keywords:Alzheimer’s disease;lignan;metabolite identification;Schisandra chinensis;target-network pharmacology;UHPLC–Q-TOF-MS
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2019
·
IF 2.931
Shengmei Song,Fan Liang,Minglu Li,Fangfang Du,Wenjuan Dong,Xiaojuan Gong,Shaomin Shuang,Chuan Dong
A fluorescent sulfur and nitrogen dual-doped carbon dots (S,N-CDs) was prepared by a simple and one-step acid-base neutralization and exothermic carbonization method. Hexavalent chromium (Cr(VI)) could effectively quench the fluorescence of S,N-CDs based on inner filter effect (IFE) and dynamic quenching, whereas ascorbic acid (AA) could recover the fluorescence of S,N-CDs/Cr(VI) because of IFE weakening. So an “on-off-on” and label-free nano-probe consecutive determination of Cr(VI) and AA was constructed. This nano-probe system demonstrated excellent selectivity and sensitivity to Cr(VI) and AA with linear range of 0.065–198 μmol/L (3.38–10,296 μg/L) and 6.6–892 μmol/L (1.16–157 mg/L), respectively. Meanwhile, the as-prepared S,N-CDs possess low toxicity and could be used for multi-color cell imaging in SMMC 7721 cells. More importantly, this nano-probe was successfully employed for detection of Cr(VI) in tap water and AA in food samples. In view of its simple detection condition, rapid response, wide linear range, low detection limit and inexpensive instrument, the as-constructed nano-probe system could have a wide range of potential application, including water quality monitoring and evaluation, food inspection and testing and biomedical analysis.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Guojun Li,Zheng Lian,Qiuqiu Lyu,Chenyu Zhu,Zhinian Liu,Shule Zhang,Qin Zhong
The efficiency of photocatalytic Nitric Oxide(NO) oxidation is limited by the lack of oxygen(O 2 ) active sites and poor charge carrier separation. To address this challenge, we developed a molecular Cobalt Phthalocyanine modified MIL-68(In)–NH 2 photocatalyst with a robust Built-in electric field(BIEF). In the 2 % CoPc-MIN sample, the BIEF strength is increased by 3.54 times and 5.83 times compared to pristine CoPc and MIL-68(In)–NH 2 , respectively. This BIEF facilitates the efficient S-scheme charge transfer, thereby enhancing photogenerated carrier separation. Additionally, the Co-N4(II) sites in CoPc can effectively trap the separated photoexcited electrons in the S-scheme system. In addition, the Co-N4(II) sites can also serve as active sites for O 2 adsorption and activation, promoting the generation of superoxide radical ( O 2 – ), thereby driving the direct conversion of NO to nitrate(NO 3 – ). Consequently, the 2 % CoPc-MIN sample exhibits a remarkable photocatalytic NO removal efficiency of 79.37 % while effectively suppressing the formation of harmful by-product nitrogen dioxide(NO 2 ) to below 3.5 ppb. This study provides a feasible strategy for designing high-efficiency O 2 activation photocatalysts for NO oxidation.
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APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2016
·Vol. 181
·期 4
·1347-1359
·
IF 1.606
Dai Yong,Huan Bin,Zhang Hai-Sheng,He Yu-Cai
To increase the biocatalytic activity of Escherichia coli CCZU-T15 whole cells, choline chloride/glycerol ([ChCl][Gly]) was firstly used as biocompatible solvent for the effective biotransformation of ethyl 4-chloro-3-oxobutanoate (COBE) into ethyl ( S )-4-chloro-3-hydroxybutanoate [( S )-CHBE]. Furthermore, L-glutamine (150 mM) was added into [ChCl][Gly]–water ([ChCl][Gly] 12.5 vol%, pH 6.5) media instead of NAD + for increasing the biocatalytic efficiency. To further improve the biosynthesis of ( S )-CHBE (>99 % e.e. ) by E. coli CCZU-T15 whole cells, Tween-80 (7.5 mM) was also added into this reaction media, and ( S )-CHBE (>9 % e.e. ) could be effectively synthesized from 2000 and 3000 mM COBE in the yields of 100 and 93.0 % by whole cells of recombinant E. coli CCZU-T15, respectively. TEM image indicated that the cell membrane was permeabilized and lost its integrity and when the cell was exposed to [ChCl][Gly]–water media with Tween-80. Clearly, this bioprocess has high potential for the effective biosynthesis of ( S )-CHBE (>99 % e.e. ).
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ACS Sensors
·
2024
·
IF 8.2
Fan Shi,Zejun Zhang,Behisht Ara,Zhitan Huang,Qifeng Gui,Ahmad Mansoor,Wei Sun
Fe single-atom and Fe cluster-coupled N, S co-doped carbon nanomaterials (FeSA–FeONC-NSC) were prepared through a two-step high-temperature pyrolysis process using Gelidium corneum enriched with C, Fe, O, N, and S as precursors. The analysis by aberration-corrected scanning transmission electron microscopy and X-ray absorption spectroscopy revealed the presence of single-atom Fe in Fe–N4 coordination structures, along with small clusters as Fe–O-coordinated Fe2O3. Single-atom Fe in the form of Fe2+/Fe3+ provides more electrocatalytic active sites, which synergistically accelerates the charge migration process in the assembly of FeSA–FeONC-NSC with Fe2O3 clusters. The flexible nonenzymatic sensor, based on FeSA–FeONC-NSC and fabricated using a polydimethylsiloxane substrate, exhibited excellent catalytic activity for both uric acid (UA) and tyrosine (Tyr). Low detection limits for UA (0.14 μmol L–1) and Tyr (0.03 μmol L–1) were observed by using chronoamperometry in artificial sweat. The in situ detection of sweat was performed in combination with an integrated circuit board affixed to human skin, and the results were generally consistent with those of the high-performance liquid chromatography method. Therefore, FeSA–FeONC-NSC serves as a good modifier for wearable electrochemical sweat sensor applications.
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2025
·
IF 3.7
Yahui Gao,Gendi Song,Yanjie Xu,Yuyu Sun,Yong Feng,Huijun Tan,Wenjie Tian
By enhancing surface interaction between metal oxide particles and carbon-based materials,it can effectively improve Faraday capacitance and conductivity, ultimately achieving high energy density with sufficient redox reactions in supercapacitors. Through a gentle biomineralization process and subsequent thermal reduction strategy, we successfully prepared the graphene oxide (GO) wrapping mixed-valence manganese oxides (MnO x ) and S, P self-codoped carbon matrix porous composite (MnOx@SPC@reduced graphene oxide (RGO)).During the biomineralization process of engineered Pseudomonas sp. (M1) cells, GO nanosheets functioned as the ‘soil’ to adsorb Mn 2+ ion and uniformly disperse biogenic Mn oxides (BMO). After undergoing annealing, the MnOx nanoparticles were evenly wrapped with graphene, resulting in the creation of the MnO x @SPC@RGO3 composite. This composite possesses strong C—O—Mn bond interfaces, numerous electroactive sites, and a uniform pore structure. By optimizing the synergistic interaction between the highly conductive graphene and the remarkable surface capacitance of MnO x , the MnO x @SPC@RGO3 electrode, with its intercalation Faraday reactions mechanism of Mn 2+ ↔ Mn 3+ and Mn 3+ ↔ Mn 4+ transformations, exhibits an outstanding specific capacity (448.3 F g −1 at 0.5 A g −1 ), multiplying performance (340.5 F g −1 at 10 A g −1 ), and cycling stability (93.8% retention after 5000 cycles).Moreover, the asymmetric all-solid-state supercapacitors of MnO x @SPC@RGO3//PC exhibit an exceptional energy density of 64.8 W·h kg −1 and power density of 350 W kg −1 , as well as a long lifespan with capacitance retention of 92.5 % after 10000 cycles. In conclusion, the synthetic route utilizing biomineralization and thermal reduction exhibits significant potential for exploiting high-performance electrode materials in all-solid-state supercapacitor applications.
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FITOTERAPIA
·
2024
·
IF 2.5
Liwenyu Chen,Yi Yu,Min Lin,Ming Liang,Chen Yang,Xutian Kan,Xiaoliang Lin,Jin Qi
Schisandra chinensis (Turcz.) Baill, a traditional Chinese medicine with significant nourishing functions, has a regulatory effect on the cardiovascular system, digestive system, central nervous system, and endocrine and immune systems. It can protect the cardiovascular system, improve immunity, and has anti-oxidant and anti-aging properties. This study aimed to identify the chisandra chinensis components that increased NAD+ levels, by using spectrum-effect analysis and experimental validations. First, the quality of the S. chinensis extract was analyzed by HPLC-MS. The extract of S. chinensis increased the NAD+ levels of HUVECs during oxygen and glucose deprivation injury, and protected HUVEC s from injury from superoxide dismutase (SOD) and aging. The relationships of spectral effects were studied by partial least square regression. Coupled with target cell extraction, the material basis for increasing NAD+ levels in S. chinensis was obtained. The pharmacological activity of S. chinensis was verified at the cellular level. The related enzymes of the NAD+ synthesis and decomposition pathways were identified, showing that S. chinensis increased the level of NAD+ by increasing the activity of related enzymes in the synthesis pathways of NMNAT1, NMNAT2, NMNAT3, and NAMPT, but had no effect on the decomposition pathway. Finally, four constituents were confirmed, in vitro, to be the basis of S. chinensis -induced increases in the levels of NAD+. The EC 50 values of the four constituents were also determined.
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Polymer Chemistry
·
2010
·Vol. 1
·期 8
·1205-1214
·
IF 0
Peng-Fei Gou,Wei-Pu Zhu,Zhi-Quan Shen
Novel well-defined drug-grafted seven-arm amphiphilic star poly(ε-caprolactone-co-carbonate)-b-poly(ethylene glycol)s based on a β-CD core [CDS-P(CL-co-DTC)-D-b-PEG] have been synthesized by the combination of controlled ring-opening polymerization (CROP), esterification coupling reactions and “click” reactions. First, 5,5-dibromomethyl-trimethylene carbonate (DBTC) bearing two bromide pendent groups was synthesized and used to copolymerize with CL to prepare seven-arm star random copolymers [CDS-P(CL-co-DBTC)] in the presence of per-2,3-acetyl-β-cyclodextrin and Sn(Oct)2. Second, esterification coupling reaction between CDS-P(CL-co-DBTC) and carboxyl-terminated mPEG led to amphiphilic seven-arm star copolymers [CDS-P(CL-co-DBTC)-b-PEG]. Subsequently, the bromide pendent groups on CDS-P(CL-co-DBTC)-b-PEG had been converted into azide groups by treating with NaN3. Finally, alkyne functionalized ibuprofen had been grafted onto the hydrophobic block of the star copolymers by copper(I)-catalyzed “click” reaction. 1H NMR, FT-IR and SEC analyses confirmed the well-defined drug grafted star architecture. These copolymers could self-assemble into multi-morphological aggregates in water, which were characterized by dynamic light scattering (DLS) and transmission electron microscopy (TEM).
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MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Chenglong Xue,Zhanpeng Ren,Jianying Wang,Minghua Deng,Jiashen Li,Xianbao Wang,Jinhua Li
The conventional methods for detecting Hg 2+ ions are generally impaired by low sensitivity, a high limit of detection (LOD), and the long detection time required. In this work, we develop a novel solution gated graphene transistor (SGGT) based on carbon dots doped with N and S elements (N/S CDs) as gate electrode probes. The prepared N/S CDs, which are 3–5 nm in diameter, are first modified at the gate of the SGGT through covalent bonding that specifically recognizes Hg 2+ ions. The SGGT is then used as a Hg 2+ sensor, exhibiting good selectivity, ultrahigh sensitivity, good reproducibility, and a short detection time. The SGGT sensor has an excellent linear detection range, from 0.1 fM to 1 nM. The LOD can reach 28 aM, which is far lower than that of conventional detection methods. Moreover, the SGGT sensor also has a rapid response time of ∼ 40 s. Finally, the ability to analyze real water samples and serum samples is demonstrated.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Guocui Cai,Helong Jiang,Fangyi Chu,Xiangcun Li,Xiaobin Jiang,Xiao Wu,Gaohong He,Yan Dai
Here, the conventionally disordered Co(OH)F filaments are rearranged to form highly-ordered flower-like Co(OH)F architectures in a conductive membrane substrate. The important findings contribute to designing delicate nanostructures and improving the catalytic activity of advanced materials for energy applications. The hierarchically porous CNT@NC membrane with CNT as the core and N -doped carbon as the crosslinking shell is scalably designed firstly for strengthening the transport of Li + and electrons in the electrode, providing an ultrahigh porosity for growing flower-like Co(OH)F on both surfaces and interior of the membrane, as well as offering electrons for the redox reactions through the roots of the Co(OH)F flowers. Furthermore, the ordered Co(OH)F bundles with divergent and open-ended structures provide the catalyst with the broad reaction interface and active sites for polysulfides (LiPSs) anchoring and catalytic conversion at a low energy barrier, significantly facilitating the diffusion of ions and electrolyte in the catalyst, and thus effectively alleviating the shuttle effect. Owing to the synergistic effect between the conductive membrane substrate and the grown Co(OH)F catalyst, the Co(OH)F-CNT@NC cathode generates a high reversible capacity and excellent long-term cycling performance (622 mAh·g −1 at 1C after 600 cycles). Conclusively, the proposed facile strategy provides insights regarding the design of novel cathode materials for high-areal-capacity Li–S batteries.
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