CHEMISTRY-A EUROPEAN JOURNAL
·
2019
·Vol. 25
·期 51
·11940-11944
·
IF 5.16
Jinxing Chen,Weiwei Wu,Liang Huang,Qian Ma,Shaojun Dong
In addition to superior enzyme-mimicking abilities, nanozymes also have intrinsic physicochemical properties. Integrating the enzyme-like activities and tunable physicochemical properties into a single nanoparticle is a promising strategy for versatile nanozyme design and application. Herein, a composite nanozyme in which Au nanoparticles are encapsulated by Au nanoclusters (AuNP@AuNCs) is presented. By integrating the peroxidase-mimicking ability of fluorescent Au NCs with the glucose oxidase-like activity of Au NPs, the composite nanozyme realized cascade assay of glucose without the aid of external indicators. Compared to traditional multistep colorimetric methods, the analytical process was highly simplified by using the self-responsive nanozyme. This synthetic strategy provided valuable insights into exploring talented nanozymes for sensing diverse targets. Graphical Nanozymes : By integrating the peroxidase-mimicking ability of fluorescent Au nanoclusters with the glucose oxidase-like activity of Au nanoparticles, a composite nanozyme that is capable of cascade assay of glucose without the aid of external indicators was fabricated (see figure).
研究领域:
纳米技术
·
生物传感器
·
酶模拟
·
分析化学
✓ 已验证
DOI
高影响因子
Chem Catalysis
·
2025
·
IF 11.6
Yunfeng Bao,Jingzhen Zhang,Shiwen Du,Sanlue Hu,Yejun Xiao,Zhaochi Feng,Fuxiang Zhang
Inorganic mixed-anion semiconductor photocatalysts are promising for water splitting due to their broad visible light absorption and structural stability. However, efficient photocatalytic production of hydrogen peroxide (H 2 O 2 ) remains challenging. This study reports a one-step photocatalytic method for H 2 O 2 production using the synthesized β-ZrNBr inorganic nanosheet photocatalyst, achieving an apparent quantum efficiency of 11.7% at 420 ± 10 nm and a solar-to-H 2 O 2 efficiency of 0.5%. This superior H 2 O 2 synthesis performance is attributed to efficient carrier mobility, high bulk charge carrier separation efficiency exceeding 70%, and the ability to directly promote water oxidation into H 2 O 2 . Additionally, 600 μmol L −1 g cat −1 of H 2 O 2 can be continuously generated over the β-ZrNBr film without significant decay under visible light in a homemade flow cell. Our work offers a scalable alternative for H 2 O 2 production using robust inorganic semiconductors under ambient conditions.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2025
·
IF 21.1
Jiahao Liu,Zhaorui Zhang,Chenshuai. Han,Zhihang Xu,Ye Zhu,J. Paul Attfield,Jianrong Zeng,Minghui Yang
Hydrogen peroxide (H 2 O 2 ) is a clean and versatile oxidant with significant applications in marine pollution treatment. Direct electrosynthesis of H 2 O 2 via the two-electron oxygen reduction reaction (2e - ORR) from seawater offers a sustainable and efficient alternative by eliminating the need for H 2 O 2 transport and storage. Herein, we report a 2-bromothiophene-modified nickel nitride (D-Ni 3 N) catalyst that optimizes oxygen adsorption to selectively enhance the 2e - ORR pathway while mitigating halide-induced corrosion and alkaline earth salt precipitation. D-Ni 3 N achieves a remarkable H 2 O 2 yield rate of 4.69 mol·h −1 ·g −1 with a Faradaic efficiency of 94.6 %, sustaining continuous operation for over 120 hours in natural seawater. Notably, the capital cost of 70 wt% H 2 O 2 is remarkably low at just $0.20 kg −1 . This work highlights the transformative potential of ligand-modified metal nitrides as stable and efficient 2e - ORR catalysts for sustainable H 2 O 2 production in seawater purification applications.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Food Bioscience
·
2021
·
IF 4.24
Qiang Chu,Ruoyi Jia,Chaowei Chen,Yaxuan Wang,Xin Yu,Yiru Zhang,Tao Wu,Xiaodong Zheng
Apios americana Medik leaves are rich in polyphenols and prevent glucose-induced damage in organisms. Polyphenols are a group of natural antioxidants. Therefore, a H 2 O 2 induced oxidative stress model of HepG2 cells was used to explore the protective effects of the Apios americana Medik leaves water extract (ALWE) against oxidative stress. Nine compounds were identified in ALWE using HPLC-TOF-MS including C 18 H 24 O 13 , which had not previously been reported. Fluorescence staining assays showed that the ALWE significantly decreased apoptosis, intracellular ROS generation, mitochondrial membrane potential (MMP) dissipation and mitochondrial membrane lipid peroxidation after ALWE pretreatment. Data from western blots showed that Keap1-Nrf2 and Sirt1-FoxO1 signaling pathways were involved in preventing H 2 O 2 induced oxidative stress. Transmission electron microscope and Western blot analyses indicated that autophagy contributed to the regulation of the oxidative balance. These results together indicated that ALWE is a potential antioxidant and autophagy activator, and it protects HepG2 cells against H 2 O 2 damage through activation of autophagy.
研究领域:
药理学
·
细胞生物学
·
分子生物学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 42
·32897-32901
·
IF 3.84
Miaolin Yin,Lifang Zhao,Qin Wei,He Li
A simple, rapid and sensitive detection method by the naked eye for melamine in dairy products is reported. Within 60 min, melamine can be detected as low as 0.4 μM by UV-vis spectrometric or naked eye observation, which is far below the melamine safety limit in the USA and EU.
研究领域:
食品科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
NANO
·
2020
·
IF 1.566
Zhikun Zhang,Qingqing Liu,Yumin Liu,Ran Qi,Lilong Zhou,Zhengjie Li,Jimmy Yun,Runjing Liu,Yongqi Hu
In view of the importance of convenient and rapid H 2 O 2 detection for biological analysis, we herein propose Ag nanoparticle (NP)-decorated silica microspheres as a probe for instant and non-enzymatic on-site colorimetric detection of H 2 O 2 . The surface hydroxyl groups of silica microspheres were reacted with (3-mercaptopropyl)trimethoxysilane to afford thiolated microspheres that subsequently bind Ag NPs. The oxidation of residual –SH groups on the silica surface to –S–S– moieties in the presence of H 2 O 2 induces the aggregation of decorated microspheres and is accompanied by a color change. Sensor response is found to be proportional to H 2 O 2 concentration in the range from 100 nM to 1 mM, with UV–Vis and colorimetric detection limits determined as 10 − 8 M and 10 − 5 M, respectively. The developed platform is successfully used to detect H 2 O 2 in simulated human urine and is, therefore, concluded to be sufficiently stable and selective for practical applications.
研究领域:
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Qiong Sun,Bing Han,Kaijing Li,Liyan Yu,Lifeng Dong
Photocatalytic fuel cell (PFC) is a novel energy conversion device that can effectively convert light into chemical energy and then electrical energy, accompanied with the pollutant purification treatment by photocatalytic technology. In this study, the synergetic photocatalytic degradation of organic dye in anode and the reduction of heavy metal Cr(VI) in cathode are carried out in an improved dual-chamber PFC device with TiO 2 and core–shell structured Ag@Fe 2 O 3 nanoparticles as photoanode and cathode materials , respectively. Among different materials, Ag@Fe 2 O 3 shows the highest catalytic activity to the reduction of Cr(VI) with an apparent kinetic constant of 0.058 min −1 , even much better than commercial Pt foil (0.027 min −1 ). From morphology and electrical characterizations, the excellent electrical conductivity of noble metal Ag and suitable conduction band positions between TiO 2 and Fe 2 O 3 lead to a rapid and directional transfer of photoinduced electrons, and the variable valence of Fe(II)/(III) in iron oxide facilitates continuous catalytic reduction of Cr(VI) to Cr(III). Moreover, the addition of H 2 O 2 into anode chamber can significantly accelerate the reactions and electricity output. The radical quenching tests prove that the existence of H 2 O 2 can efficiently increase the production of photoinduced carriers, and more oxidizing species (such as O 2 − and OH) can be produced from the reactions between H 2 O 2 and photoinduced holes or electrons.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
Biotechnology Journal
·
2024
·Vol. 19
·期 4
·2300584
·
IF 3.2
Jingjia Liu,Nan Zhang,Bowen Shen,Liling Zhang,Zhidong Zhang,Liying Zhu,Ling Jiang
The use of a combination of several antibacterial agents for therapy holds great promise in reducing the dosage and side effects of these agents, improving their efficiency, and inducing potential synergistic therapeutic effects. Herein, this study provides an innovative antibacterial treatment strategy by synergistically combining R12-AgNPs with H 2 O 2 therapy. R12-AgNPs were simply produced with the supernatant of an ionizing radiation-tolerant bacterium Deinococcus wulumuqiensis R12 by one-step under room temperature. In comparison with chemically synthesized AgNPs, the biosynthesized AgNPs presented fascinating antibacterial activity and peroxidase-like properties, which endowed it with the capability to catalyze the decomposition of H 2 O 2 to generate hydroxyl radical. After the combination of R12-AgNPs and H 2 O 2 , an excellent synergistic bacteriostatic activity was observed for both Escherichia coli and Staphylococcus aureus , especially at low concentrations. In addition, in vitro cytotoxicity tests showed R12-AgNPs had good biocompatibility. Thus, this work presents a novel antibacterial agent that exhibits favorable synergistic antibacterial activity and low toxicity, without the use of antibiotics or a complicated synthesis process.
研究领域:
微生物学
·
纳米生物学
·
抗菌研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2022
·Vol. 20
·期 1
·1-15
·
IF 9.429
Zhang Ruiyi,Liu Teng,Li Wanzhen,Ma Zhiyuan,Pei Pei,Zhang Weiwei,Yang Kai,Tao Yugui
Tumor microenvironment (TME), characterized by high glutathione (GSH), high hydrogen peroxide (H2O2) and acidic pH levels, is favorable for the growth, invasion and metastasis of cancer cells. Taking advantage of the specific characteristics of tumors, TME-responsive GCBD NPs are designed to deliver nanoscale coordination polymers (NCPs, GA-Cu) and chemotherapy drugs (doxorubicin, DOX) based on bovine serum albumin (BSA) nanocarriers into cancer cells for combined chemodynamic therapy (CDT) and chemotherapy. In an acidic environment, GCBD NPs could release approximately 90% copper ions, which can not only consume overexpressed GSH to modulate the TME but can also react with endogenous H2O2 in a Fenton-like reaction to achieve the CDT effect. Meanwhile, the released DOX could enter the nucleus of tumor cells and affect their proliferation to achieve efficient chemotherapy. Both in vitro and in vivo experiments showed that GCBD NPs had good biosafety and could effectively inhibit the growth of cancer cells. GCBD NPs are promising as a biocompatible nanoplatform to exploit TME characteristics for combined chemo and chemodynamic therapy, providing a novel strategy to eradicate tumors with high efficiency and specificity.Graphical Abstract
研究领域:
肿瘤学
·
纳米医学
·
生物材料学
✓ 已验证
DOI
PubMed
高影响因子
ACS Omega
·
2018
·
IF 0
Qiangying Zhang,Man He,Beibei Chen,Bin Hu
In this paper, magnetic mesoporous carbon composites were prepared by calcination of the mixture of magnesium citrate and Fe3O4@SiO2 in an inert atmosphere. A high content of Fe3O4@SiO2 and MgO was in situ embedded in a carbon matrix. After removing the MgO template by diluted acid, the resulting material (Fe3O4@SiO2@mC) was subjected to further H2O2 oxidation treatment. The formed oxygen-containing functional groups on the products provided plenty of active sites for the adsorption of analytes of interest. The obtained composites (Fe3O4@SiO2@mC-H2O2) exhibited a mesoporous structure with a high specific surface area of 731 m2 g–1. The adsorption capacities of Fe3O4@SiO2@mC-H2O2 for Cu(II) and Pb(II) were calculated to be 86.5 and 156 mg g–1, respectively. Under optimal conditions, the adsorption isotherm of Cu(II) and Pb(II) onto Fe3O4@SiO2@mC-H2O2 fitted the Langmuir model and the adsorption kinetic was well-correlated with the pseudo-second-order model. Besides, Fe3O4@SiO2@mC-H2O2 exhibited fast removal dynamics (within less than 1 min) for Cu(II) and Pb(II), demonstrating great application potential in wastewater treatment.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
PubMed
JOURNAL OF HAZARDOUS MATERIALS
·
2015
·
IF 4.529
Shaopeng Rong,Yabing Sun
This work describes the application of plasma generated by water falling film dielectric barrier discharge for the degradation of triallyl isocyanurate (TAIC). The results indicated that TAIC solution of 1000 mg/L was effectively removed within 60 min treatment at 120 W output power. Six intermediates were identified and a possible evolution of the TAIC degradation process was continuously proposed basing on the results of mass spectrum analysis. The effects of metal ions and radical scavengers were investigated. Results showed that whatever hydrogen radical scavengers (carbon tetrachloride, perfluorooctane) or hydroxyl radical scavengers ( iso -propyl alcohol, tert -butyl alcohol) all could further enhance the degradation processes, and both kings of radical scavengers could promote the generation of H 2 O 2 . In the present study, we employed a novel method by introducing the mixed additives of Fe 2+ and radical scavengers into the plasma. It was found that the reaction rate constant and energy efficiency were improved by 309.2% and 387.8%, respectively. Among the mixed additives, Fe 2+ could promote the decomposition and increase the oxidizing power of H 2 O 2 , which is generated from the plasma discharge and greatly enhanced by the radical scavengers.
研究领域:
环境科学
·
化学工程
·
等离子体技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2021
·Vol. 38
·期 4
·985-990
·
IF 1.307
Shi Rui,Wei Shuxian,Cheng Shiqi,Zeng Jinmin,Wang Yilin,Shu Xin
In the present work, WO 3 nanosheets(WO 3 NSs) were prepared by a facile method at room temperature. The obtained WO 3 NSs showed peroxidase-like activity, which could catalyze 3,3’,5,5’-tetramethylbenzidine(TMB) to form a blue oxidation product(ox TMB) in the presence of H 2 O 2 . Based on this, convenient and sensitive colorimetric methods for the detection of H 2 O 2 and glucose were established. The linear ranges for detecting H 2 O 2 and glucose were 1–200 µmol/L and 1–100 µmol/L, respectively. The limits of the detection of H 2 O 2 and glucose were as low as 0.79 and 0.96 µmol/L, respectively. This method was also successfully applied to the detection of glucose in urine samples. The detection result was consistent with that of the value detected by the clinical method, indicating the potential in clinical diagnosis and biomedical detection.
研究领域:
生物化学
·
医学诊断
·
纳米材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）