FOOD CHEMISTRY
·
2015
·
IF 3.391
Xueke Liu,Zhigang Shen,Peng Wang,Chang Liu,Guojun Yao,Jiayuan He,Donghui Liu,Zhiqiang Zhou
Isomerization of chiral pesticides in residue analysis has not drawn much attention which can cause wrong decisions on the enantioselective environmental behavior. A residue analysis method for α-cypermethrin and its three acid metabolites, cis/trans-3-(2,2-dichlorovinyl)-2,2-dimethyl cyclopropanecarboxylic acid (cis/trans-DCVA) and 3-phenoxybenzoic acid (3-PBA), in foods such as chicken, honey, milk and pork has been established, in which the isomerization of α-cypermethrin was minimized. The target compounds were determined by GC–ECD after a derivatization reaction with 1,1,1,3,3,3-hexafluoroisopropanol. The conditions of the method were optimized by Taguchi orthogonal experiment. Under the optimized conditions, good linearity was obtained with correlation coefficients ranging from 0.9964 to 0.9998. The limits of detection were 0.001–0.005 mg kg −1 . The recoveries were 70.9–114.9% with relative standard deviations of 0.6–15%. In addition, ratios of isomerization ranged only from 2.3% to 7.0%. This method was applied in commercial animal food products.
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CHINESE JOURNAL OF CHEMISTRY
·
2015
·Vol. 33
·期 4
·409-412
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IF 1.578
Dazhao Sun,Guofang Jiang,Zongbo Xie,Zhanggao Le
A novel methodology for the synthesis of bis(indolyl)methanes by the reaction of aromatic aldehydes and indole in water has been developed, and a series of desired products were obtained in moderate to excellent yields (from 65% to 97%) using 1.2 mg/mL α -chymotrypsin as biocatalyst.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2016
·Vol. 27
·期 7
·6829-6834
·
IF 1.798
Su Chang,Li Yu,Li Shouchun,Liu Li,Guo Xuexin,Lian Hongwei,Guan Xiulong
Pure and Pr-doped α-Fe 2 O 3 nanotubes are successfully synthesized via electrospinning and following calcined method. The crystal, morphologies structures and composed of the as-prepared samples are investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS), respectively. The researches of the gas sensing properties of the samples show that Pr-doped α-Fe 2 O 3 nanotubes possess excellent sensitive to ethanol, and the response value of Pr-doped α-Fe 2 O 3 nanotubes to 10 ppm ethanol is 21.3 at the operating temperature 240 °C, which is much higher than that of pure α-Fe 2 O 3 nanotubes (1.5). That is to say that the ethanol sensitive of α-Fe 2 O 3 nanotubes is improved remarkably by doping Pr. Moreover, Pr-doped α-Fe 2 O 3 nanotubes show good selectivity and long-term stability.
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DYES AND PIGMENTS
·
2024
·
IF 4.1
Weifeng Ma,Wei Jia,Yanjing Gao,Fang Sun
In this study, we designed and synthesized four α-ketone aryl thioesters photoinitiators ( PTEs ) with excellent cytocompatibility for LED photopolymerization using a simple one-step reaction. We investigated the potential photopolymerization initiation mechanisms of PTEs under 405 nm LED irradiation through ultraviolet–visible absorption spectroscopy, high-resolution mass spectroscopy, and electron spin resonance. Our findings revealed that PTEs can effectively initiate the photopolymerization of acrylate monomer tripropylene glycol diacrylate (TPGDA) under either 405 nm or 455 nm LED irradiation, achieving double bond conversions of approximately 80 % or higher after 180 s of irradiation. Remarkably, compared to the commercial photoinitiator 2,4,6-trimethylbenzoyl-diphenylphosphine oxide (TPO) and benzoyl methacrylate (MBF), PTEs exhibit certain advantage in initiating photopolymerization of triethylene glycol dimethacrylate (TEGDMA) widely used for dental materials under the irradiation of 405 nm. More importantly, MO-PTE has better cytocompatibility compared to TPO and exhibits a great potential in the fields of LED photopolymerization, biomaterials and food packaging.
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2025
·
IF 4.9
Yuanxin Pian,Yan Hao,Yuxin Guo,Shiqi Wu,Saijiao Tang,Jiaqi Li,Xinya Lu,Xiaoya Sun,Zhaowen Tan,Tianyu Zhu,Yuxiang Tang,Defeng Xu,Hang Hu
Facile and efficient drug loading and delivery strategies hold paramount importance in the development of advanced pharmaceutical formulations, enhancing both the efficacy and accessibility of treatments. In this study, we successfully prepared dimethylcurcumin (DMC)-loaded α-crocin nanoparticles with varying drug loadings (15.2 % and 21.7 %) using a solvent diffusion method, which exhibit excellent lyophilization stability, relatively small and uniform particle sizes. DMC is encapsulated in an amorphous state within α-crocin nanoparticles, forming strong π-π stacking interactions. Dissipative particle dynamics simulations and transmission electron microscope images confirm the core-shell structure, with DMC aggregates forming the cores and α-crocin coating the surfaces. The drug loading studies on various drugs with different structure and properties show that hydrophobic drugs with π-conjugated systems and planar structures can be efficiently encapsulated with α-crocin. The nanoparticles exhibit sustained drug release in pH 7.4 and pH 5.0 conditions and demonstrate enhanced antitumor activity in vitro compared to free drugs, with DMC@α-Crocin (15.2 %) nanoparticles showing superior performance due to higher cellular uptake. Pharmacokinetic study reveals prolonged blood half-life and increased area under curve for DMC@α-Crocin (15.2 %) nanoparticles, indicating improved drug delivery. This work validates the potential of α-crocin-based drug encapsulation for enhanced cellular uptake, antitumor activity, and prolonged blood circulation, providing new insights into the development of efficient drug delivery system.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Mengting Wang,Wenwen Guo,Zhijian Ke,Haiguang Mao,Jimin Lv,Lili Qi,Jinbo Wang
Theaflavins, oxidation product of tea polyphenols, have demonstrated significant inhibitory effects on α-glucosidase, which is beneficial in alleviating hyperglycemia. This study found that the inhibition of four monomers of theaflavins on α-glucosidase was related to the presence of the galloyl moiety (GM), with IC 50 values ranging from TFDG (0.26 mg/mL) < TF3′G (0.33 mg/mL) < TF3G (0.39 mg/mL) ≪ TF (3.26 mg/mL). The multi-spectroscopic analyses revealed that theaflavin monomers changed the microenvironment around aromatic amino acid residues and conformation of α-glucosidase, with the hierarchy being TFDG > TF3′G > TF3G > TF. The binding of theaflavins with α-glucosidase was confirmed by differential scanning calorimetry (DSC), isothermal titration calorimetry (ITC), molecular docking and molecular dynamics simulations analysis. It was confirmed that theaflavins can form stable complexes with α-glucosidase, and that hydrogen bonding and van der Waals forces play important roles in the binding of theaflavins to α-glucosidase. The strongest binding affinity was observed between TFDG and the enzyme's active site, which corresponded with its enzyme activity inhibition ability. The study suggests that GM substitution plays a crucial role in enhancing the binding of theaflavins to α-glucosidase, thereby inducing greater conformational changes and leading to a stronger inhibitory effect on α-glucosidase.
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JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
·
2018
·Vol. 29
·期 2
·404-411
·
IF 1.444
Song Jia-Xing,Fang Xiang,Guo Tao,Bei Feng-Li,Ding Wen,Zhang Xiao-Nan,Yao Miao,Yu Hong-Jun
In this work, thermal properties and kinetics of Al-nanoparticles/α-MnO2 nanorods thermite were reported. The α-MnO2 nanorods were synthesized using a hydrothermal method and were characterized by X-ray powder diffraction (XRD) and X-ray photoelectron spectra (XPS), then combined with Al nanoparticles based on the ultrasonic mixing method to prepare the nanostructure thermite. Besides, both pure components and mixture were characterized by field emission scanning electron microscopy (FE-SEM) to observe their morphologies and structures. Subsequently, the thermal properties of Al/α-MnO2 nanostructure thermite were studied on the basis of thermogravimetric-differential scanning calorimetry (TG-DSC). According to the TG-DSC tests, the calculation results of activation energy for kinetics of Al/α-MnO2 thermite were obtained using different isoconversional methods. It was found that Al/α-MnO2 nanostructure thermite has high heat release and low onset temperature, and the heat release of the nanostructure thermite was approximately 1146.6 J g -1.
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Energy Advances
·
2024
·Vol. 3
·期 7
·1571-1580
·
IF 3.2
Zhaocai Jiao,Mingzu Liu,Ningbo Yang,Fengli Yu,Congxia Xie,Shitao Yu,Bing Yuan
α-Pinene and isobutene/isobutane can undergo hybrid alkylation under acid catalysis, resulting in C14 and C20 product fractions with favorable bio-based high-energy-density fuel properties after hydrogenation. In this study, the catalytic performance of zeolite molecular sieves, such as Hβ, HY, HZSM-5, HZSM-35, HSAPO-11, was investigated for the alkylation of α-pinene and Isobut-5 (a mixture of isobutene/isobutane with a mass ratio of 1 : 5) given the acidic sites and specific pore structures with shape-selective abilities of zeolite catalysts. Various characterization techniques, including temperature-programmed desorption of ammonia (NH3-TPD), Fourier transform infrared spectroscopy with pyridine adsorption (Py-IR), N2 adsorption/desorption, X-ray fluorescence spectrum (XRF), and particle size analysis, were conducted to analyze the acidic properties, pore characteristics, silica–aluminum ratio, and grain size of the zeolites, and their influence on the alkylation of α-pinene and Isobut-5. Moreover, the recycling performance of the favorite Hβ-25n catalyst and an effective regeneration method were investigated using temperature-programmed oxidation (TPO) analysis. This study provides essential research data for the preparation of α-pinene-based high-energy-density fuels.
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Nature Communications
·
2024
·Vol. 15
·期 1
·1-10
·
IF 14.7
Wang Tianjiao,Xin Yu,Chen Bingfeng,Zhang Bin,Luan Sen,Dong Minghua,Wu Yuxuan,Cheng Xiaomeng,Liu Ye,Liu Huizhen,Han Buxing
Achieving selective hydrodeoxygenation of α, β-unsaturated carbonyl groups to alkenes poses a substantial challenge due to the presence of multiple functional groups. In this study, we develop a ZnNC-X catalyst (X represents the calcination temperature) that incorporates both Lewis acidic-basic sites and Zn-N x sites to address this challenge. Among the catalyst variants, ZnNC-900 catalyst exhibits impressive selectivity for alkenes in the hydrodeoxygenation of α, β-unsaturated carbonyl compounds, achieving up to 94.8% selectivity. Through comprehensive mechanism investigations and catalyst characterization, we identify the Lewis acidic-basic sites as responsible for the selective hydrogenation of C=O bonds, while the Zn-N x sites facilitate the subsequent selective hydrodeoxygenation step. Furthermore, ZnNC-900 catalyst displays broad applicability across a diverse range of unsaturated carbonyl compounds. These findings not only offer valuable insights into the design of effective catalysts for controlling alkene selectivity but also extend the scope of sustainable transformations in synthetic chemistry.
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LANGMUIR
·
2025
·
IF 3.9
Zhengquan Jiang,Chenglong Wang,Wenwei Ma,Ming Li,Laigui Yu,Shengmao Zhang,Weihua Li
Friction and wear remain formidable challenges for mechanical components in modern industrial applications. Traditional lubricants rely on a combination of additives that synergistically enhance performance but often undergo thermal degradation at increased temperatures, causing mechanical lubrication failure. Trinickel disulfide (Ni3S2) nanoparticles have emerged as promising candidates owing to their excellent tribological properties, chemical stability, and resilience at high temperatures. Compared with nonmagnetic nanoparticles, the magnetic properties of Ni3S2 nanoparticles can quickly form a protective film on the metal surface and reduce mechanical damage. Nevertheless, the conventional synthesis route of Ni3S2 requires high-temperature conditions and the release of toxic gases, resulting in environmental pollution. To address these limitations, we synthesized oleylamine-modified magnetic Ni3S2 nanoparticles (OA-Ni3S2 NPs) through a liquid-phase approach under mild conditions. Transmission electron microscopy (TEM) analysis indicated that OA-Ni3S2 NPs had an average particle size of ∼40 nm. Tribological evaluation in poly-α-olefin-6 (PAO6) base oil, conducted using a four-ball tribometer, revealed that OA-Ni3S2 NPs reduced the coefficient of friction (COF) by 31% and wear scar diameter (WSD) by 40% compared to pristine PAO6, underscoring their exceptional friction-reducing and antiwear performance, while mechanistic studies further clarified the sliding behavior of the nanoparticles at the friction interface. These findings underscore the potential of OA-Ni3S2 NPs as sustainable lubricant additives and provide a promising foundation for their deployment in high-temperature industrial systems.
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SENSORS
·
2024
·Vol. 24
·期 8
·2604
·
IF 3.4
Zhihua Zhao,Zhenli Lv,Zhuo Chen,Baocang Zhou,Zhigang Shao
Metal oxide semi-conductors are widely applied in various fields due to their low cost, easy processing, and good compatibility with microelectronic technology. In this study, ternary α-Fe2O3/TiO2/Ti3C2Txnanocomposites were prepared via simple hydrothermal and annealing treatments. The composition, morphology, and crystal structure of the samples were studied using XPS, SEM, EDS, XRD, and multiple other testing methods. The gas-sensing measurement results suggest that the response value (34.66) of the F/M-3 sensor is 3.5 times higher than the pure α-Fe2O3sensor (9.78) around 100 ppm acetone at 220°C, with a rapid response and recovery time (10/7 s). Furthermore, the sensors have an ultra-low detection limit (0.1 ppm acetone), excellent selectivity, and long-term stability. The improved sensitivity of the composites is mainly attributed to their excellent metal conductivity, the unique two-dimensional layered structure of Ti3C2Tx, and the heterojunction formed between the nanocomposite materials. This research paves a new route for the preparation of MXene derivatives and metal oxide nanocomposites.
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2018
·
IF 3.129
Fansheng Kong,Zhipeng Su,Lingzhong Zhang,Yaru Qin,Kai Zhang
The potential applications of grape seeds extracts (GSE) have been limited due to low bioavailability, poor water solubility and sensitivity to temperature, light and oxygen. The purpose of this study was to develop and optimize a preparation method to protect GSE with minimal loss of bioactivity when it reaches the target site. The inclusion rate of GSE reached 96.48% under optimized conditions (inclusion temperature of 40 °C, time of 120 min and mixing speed of 600 r/min). The formation of inclusion complexes with sulfobutyl ether-β-cyclodextrin (SBE-β-CD) not only increased the solubility and stability of GSE, but also retained the antidiabetic effect. The half maximal inhibitory concentration (IC 50 ) values of inclusion complex on α-glucosidase and α-amylase were 1.188 ± 0.12 mg/mL and 0.587 ± 0.04 mg/mL, respectively, which were very close to that of acarbose (1.035 ± 0.04 mg/mL and 0.513 ± 0.05 mg/mL, respectively). The results of the study revealed that the inclusion complex of GSE with SBE-β-CD has potential applications in the field of medicine and health products.
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