NANOTECHNOLOGY
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2020
·Vol. 31
·期 45
·455503
·
IF 3.551
Mingzhu Wang,Xue Wang,Shiya Feng,Daiping He,Ping Jiang
Ever-growing efforts have been devoted to developing cost-effective and earth-abundant electrocatalysts with high-performance in biosensing and energy energy conversion. In this work, amorphous nickel-phosphorus (Ni-P) nanoparticles anchoring on Ni foam (Ni-P/NF) were prepared through a facile electroless deposition approach. The morphology and composition were characterized by scanning electron microscopy, x-ray diffraction and x-ray photoelectron spectroscopy. As an integrated anode, Ni-P/NF exhibits high performance towards glucose electrochemical sensing, with a high sensitivity of 13.89 mA mM−1 cm−2, a low detection limit of 1 µM, a wide detection ranges from 2 µM to 0.54 mM, and a quick response (<10 s), as well as good selectivity and reliability for real sample analysis in human serum. In addition to electrocatalytic glucose oxidation, Ni-P/NF shows remarkable catalytic activity towards oxygen evolution reaction (OER) in alkaline solution and it only needs an overpotential of 360 mV to afford 50 mA cm−2. Moreover, Ni-P/NF shows excellent durability under alkaline OER condition. All these results demonstrate Ni-P/NF as highly efficient integrated anode in both biosensing and energy conversion.
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高影响因子
ACS Applied Nano Materials
·
2020
·
IF 0
Xuewen Huang,Sheng Xu,Wei Zhao,Mengyi Xu,Wei Wei,Jing Luo,Xiaojie Li,Xiaoya Liu
An enzymatic H2O2 biosensor with a facile fabrication method was developed based on a screen-printed carbon electrode (SPCE) modified by the assembled distinct 0D/1D nanocomposite polymeric nanoparticles/carbon nanotubes (PAKB NPs-CNTs). First, copolymer (PAKB) was synthesized with glycoprotein-affinity monomers of 3-(acrylamido)phenylboronic acid, electroactive monomers of 9-(4-vinylbenzyl)-9H-carbazole and hydrophobic monomers of butyl methacrylate, and the polymeric nanoparticles (PAKB NPs) were prepared via the self-assembly of PAKB in a selective solution. The PAKB NPs-CNTs with 0D/1D nanostructures were then prepared by mixing PAKB NPs and CNTs with the generation of π–π interactions between the carbazole groups and CNTs. The PAKB NPs-CNTs with high glycoprotein affinity and electroactivity displayed large specific surface area and could immobilize enzymes, retain horseradish peroxidase (HRP) activity, and accelerate electron transfer. Finally, the biosensor was constructed through a successive dropping of the PAKB NPs-CNTs dispersion, HRP solution, and Nafion solution on the working electrode of SPCE. This biosensor presented a wide linear range from 0.02 to 6.48 mM and a detection limit of 2.7 μM (S/N = 3), as well as high sensitivity, excellent selectivity, short response time, and good stability. More importantly, an outstanding detection performance of biosensor was demonstrated when tested in real samples and complex systems.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2020
·Vol. 18
·期 1
·1-13
·
IF 6.518
Wu Yiyong,Deng Peihong,Tian Yaling,Feng Jinxia,Xiao Jingyun,Li Junhua,Liu Jun,Li Guangli,He Quanguo
A method with high sensitivity, good accuracy and fast response is of ever increasing importance for the simultaneous detection of AA, DA and UA. In this paper, a simple and sensitive electrochemical sensor, which based on the polyvinylpyrrolidone (PVP)-graphene composite film modified glassy carbon electrode (PVP-GR/GCE), was presented for detecting ascorbic acid (AA), dopamine (DA) and uric acid (UA) simultaneously. The PVP-GR/GCE has excellent electrocatalytic activity for the oxidation of AA, DA and UA. The second-order derivative linear sweep voltammetry was used for the electrochemical measurements. The peak potential differences of DA-AA, DA-UA, and UA-AA (measured on the PVP-GR/GCE) were 212, 130 and 342 mV respectively. Besides, the over potential of AA, DA and UA reduced obviously, so did the peak current increase. Under the optimum conditions, the linear ranges of AA, DA and UA were 4.0 μM–1.0 mM, 0.02–100 μM, and 0.04–100 μM, respectively. The detection limits were 0.8 μM, 0.002 μM and 0.02 μM for AA, DA, and UA. The electrochemical sensor presented the advantages of high sensitivity and selectivity, excellent reproducibility and long-term stability. Furthermore, the sensor was successfully applied to the analysis of real samples.
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高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2020
·
IF 3.807
Taotao Fan,Li Chen,Shunguo Qiu,Chanyuan Yang,Lihua Hu,Xiong Peng,Jianwei Zhang,Zongcheng Yan
A hybrid nanocomposite of hierarchical porous zeolitic imidazolate framework-8 / three-dimensional carbon nanotubes (HP-ZIF-8/3DCNTs) has been successfully fabricated by constructing micelle by sodium dodecyl sulfate (SDS) and deep eutectic solvent (DES) aqueous solution to grow HP-ZIF-8 in situ on the 3DCNTs template. The electrochemical performance for detecting dopamine (DA) is greatly improved owing to the synergism of highly conductive CNTs and hierarchical porous ZIF-8. At the same time, the electrochemical reaction of DA on HP-ZIF-8/3DCNTs/GCE is an adsorption control process, and density function theory (DFT) calculation was performed to analysis the charge distribution and interaction force of DA and dopaminophenone in the material, forming a molecular complex with adsorption energy of −19.11 and − 25.21 kJ/mol −1 . In addition, the response current is linear when the DA content is 1.0 × 10 −7 to 1.0 × 10 −4 M, the LOD is 2.7 × 10 −8 M at S/N = 3. The electrode material has excellent selectivity, sterling reproducibility of 2.21% and satisfactory repeatability with a RSD of 1.96%, and splendid long-term stability with peak current maintained 96.03% of the initial value after 14 days. The results indicate that HP-ZIF-8/3DCNTs composite has broad application prospects in the field of electrochemical sensing, and its modification methods and theoretical concepts can potentially be applied to the research of other sensors.
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SENSORS AND ACTUATORS B-CHEMICAL
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2020
·
IF 7.1
Weilu Liu,Fan Cui,Haifeng Li,Shuang Wang,Beibei Zhuo,Shuang Wang
A novel hybrid networks of molecularly imprinted poly(9-carbazoleacetic acid) and multi-walled carbon nanotubes (MWCNTs) was developed applying the electro-polymerization technique for the simultaneous voltammetric determination of dopamine and epinephrine. A carbazole derivative, 9-carbazoleacetic acid, was synthesized and used as a monomer for the first time. Owing to the introduction of carboxyl group, as well as the π-conjugated rigid plane structure of 9-carbazoleacetic acid, the molecularly imprinted poly(9-carbazoleacetic acid) afforded sufficient non-covalent interactions with the templates, enabled a good selectivity of the sensor. The MWCNTs acted as the supportive material for the molecularly imprinted poly(9-carbazoleacetic acid), resulted in the high specific surface area and high conductivity of the sensing interface. The as-prepared hybrid networks exhibited enhanced sensitivity and selectivity in the simultaneous voltammetric determination of dopamine and epinephrine. Experimental parameters involved in the sensor fabrication process were evaluated. A wide linear range of 0.04 ∼ 70 μM were obtained for the simultaneous detection of dopamine and epinephrine. The developed sensor, that requires only 100 μL samples for analysis, was applied to detect dopamine and epinephrine simultaneously in rat plasma sample. The recoveries were found in the range from 97.15 % to 105.5 %, indicating a promising potential in medical care and biological applications.
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SURFACE & COATINGS TECHNOLOGY
·
2020
·
IF 3.784
Xia Zhao,Zanling Huang,Wanying Zhang,Yuting Ke,Fushen Lu,Rongsheng Chen,Kaifu Huo,Liangsheng Hu,Paul K. Chu
Core-shell titanium carbide/carbon (TiC@C) and titanium carbide/nitrogen-doped carbon (TiC@CNx) quasi-aligned nanofiber arrays (NFAs) are fabricated on biomedical Ti-6Al-4V by a simple thermal chemical process in the presence of benzene and pyridine at 800 °C, respectively. The morphology, structure, and composition of the TiC@C and TiC@CNx NFAs are characterized by X-ray diffraction, electron microscopy , energy-dispersive X-ray spectrometry, and Raman scattering spectroscopy. The TiC@C and TiC@CNx nanofibers consisting of highly conducting single-crystalline TiC cores and carbon shells or N-doped carbon shells have a large amount of defects and N doping endows the TiC@CNx NFAs with excellent electrochemical properties . The TiC@CNx NFAs electrode exhibits fast heterogeneous electron transfer (HET) kinetics in the Fe(CN) 6 3−/4− redox couple showing an ideal peak-to-peak potential separation (59 mV) at a high scan rate of 7000 mV s −1 . As a result, the TiC@CNx NFAs electrode has high activity in the simultaneous detection of dopamine (DA), ascorbic acid (AA), uric acid (UA), and serotonin (5-hydroxytryptamine, 5-HT) as well as high sensitivity and selectivity in the determination of DA in the presence of UA, AA, and 5-HT. The linear range for the determination of DA is 0.5–180 μM and detection limit is 8 nM (S/N = 3).
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TALANTA
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2020
·
IF 5.339
Lingli Xuan,Wenyan Liao,Meifang Wang,Huaxu Zhou,Yao Ding,Fei Yan,Jiyang Liu,Hongliang Tang,Fengna Xi
Vertically-ordered mesoporous silica-nanochannel films (VMSF) with highly ordered nanochannels, uniform and adjustable pore size, ultra-thin thickness, and high porosity, have attracted considerable attention in analysis, molecular separation, catalysis, and nanomaterial synthesis. However, their widespread applications in practical electrochemical sensing are largely limited by the poor adhesion to common electrode materials , especially the lack of highly active substrate electrode to equip mechanically stable VMSF. Herein, we report a facile strategy to fabricate VMSF on widely used sensing electrodes without the use of any chemical adhesive for developing superior VMSF based electrochemical sensors. We demonstrate that simple electrochemical polarization (anodic polarization and subsequent cathodic reduction) to activate glassy carbon electrode (GCE) can generate a suitable surface environment allowing direct growth of stable VMSF on such pre-activated GCE (p-GCE) via electrochemically assisted self-assembly (EASA). Compared to traditional VMSF electrodes with ITO or organosilane grafted GCE as substrate, the developed VMSF/p-GCE exhibits much higher electrochemical response to four redox biomarkers (norepinephrine, dopamine, tryptophan , and uric acid). In-depth insights on mechanisms of the high electrochemical activity and incorporation stability of VMSF/p-GCE are made. We further demonstrate the VMSF/p-GCE can be employed to detect dopamine in real serum samples with exceptional sensitivity, low detection potential, as well as superior anti-interference and anti-fouling performance. In addition, high selectivity is realized as the common co-existing interference substances (ascorbic acid-AA and uric acid-UA) do not interfere with the detection.
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高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2020
·
IF 3.807
Qixia Guan,Hao Guo,Rui Xue,Mingyue Wang,Xin Zhao,Tian Fan,Wenhu Yang,Mengni Xu,Wu Yang
An electrochemical sensing platform for simultaneous determination of dopamine (DA) and uric acid (UA) is constructed based on covalent organic framework materials (IL COF-1), aminofunctionalized carbon nanotubes (MWCNT-NH 2 ), and gold nanoparticles (AuNPs). The prepared sensor shows a good performance in detection of DA and UA due to porosity, large specific surface area, high conductivity and more active sites of the composite modified material. Under optimized experimental conditions, the constructed electrochemical sensor has sensitive response and good linearity to both DA and UA. Their wide linear ranges are 0.7–108 μM and 0.97–200 μM, and the detection limits are 0.21 μM and 0.29 μM (S/N = 3), respectively. The developed method has been successfully employed to determine the contents of DA and UA in dopamine injection and human urine samples. It has a satisfactory recovery rate, and the relative standard deviations (RSD) of three parallel determinations are all below 5.0%. In comparison, the constructed sensor platform has superior performance including low cost, simple structure, wide linear range and high sensitivity than some traditional methods, which is expected to be widely used in real sample analysis.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 56
·期 1
·442-456
·
IF 3.553
Ma Xiaoqing,Tang Kang-lai,Yang Mingyu,Shi Wenbing,Zhao Wenxi
Reliable determination of hydrogen peroxide (H 2 O 2 ) and glucose is vital in various fields, especially implicated in diagnosis of diabetes and oxidative stress-related diseases. Herein, yolk–shell hollow Ni/NiO@C microspheres were template-synthesized with well-defined Ni-MOF (metal–organic framework) and further worked as a bifunctional electrocatalyst for glucose oxidation in alkaline solution and H 2 O 2 reduction in neutral solution, of which the unique structure and rich pore openings provide large accessible surface areas, while the uniformly distributed Ni, NiO and C efficiently catalyze and facilitate the reaction of glucose and H 2 O 2 , thus achieving a wide linear range of 0.01 to 10 mM with a sensitivity of 1291 μA mM −1 cm −2 and a detection limit of 0.116 μM for glucose and offering a sensitivity of 32.09 μA mM −1 cm −2 , a detection limit of 0.9 μM and a linear range up to 80.7 mM for H 2 O 2 , as well as good selectivity, excellent reproducibility and long-term stability for two analytes. What’s more, the as-constructed sensors realize quantitative detection glucose in blood serum with satisfying results and can use to monitor H 2 O 2 in neutral situation. This work opens an avenue to design high-performance sensoring materials but also becomes a great candidate in practical application.
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高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 10
·1-9
·
IF 6.232
Liu Hui,Liu Bowen,Huang Pengcheng,Wu Yangyang,Wu Fang-Ying,Ma Lihua
Gold nanoparticles (AuNPs) catalyze the mild reaction between the weak reducing agent kojic acid (KA) and silver ions (Ag + ) to form Au@Ag bimetallic NPs by the combination of the intrinsic catalysis with plasmonic properties This is proposed as a novel optical assay to determine the tyrosinase (TYRase) concentration. The nanoparticles have been characterized by UV-vis spectroscopy, transmission electron microscope (TEM) images, and X-ray photoelectron spectroscopy (XPS). The sensing mechanism is based on the fact that KA binds to TYRase by chelating with dicopper active site of TYRase and the introduction of TYRase restrains the Au@Ag bimetallic NP formation by the precedent binding with KA. A clear color variation from yellow to pink and UV-vis spectral changes are observed at the optimal wavelength of 410 nm. The assay works in the range 0.13~0.73 U mL −1 with a detection limit (LOD) of 0.019 U mL −1 . The impact from matrix interfering substances including glucose, uric acid, common oxidases, and amino acids is negligible. The applicability is demonstrated by quantitative determination of TYRase in human serum samples with 74 to 89% recovery and RSD less than 4.0%, which accords with the level for bio-sample analysis.
Schematic presentation of colorimetric assay for tyrosinase (TYRase) based on the inhibition effect on silver deposition onto catalytically active gold nanoparticles (AuNPs) and its application with a smartphone. Tyrosinase (TYRase); silver ions (Ag + ); kojic acid (KA); gold nanoparticles (AuNPs); gold-silver core-shell nanoparticles (Au@Ag NPs)
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高影响因子
Micro & Nano Letters
·
2020
·Vol. 15
·期 15
·1071-1074
·
IF 0.975
Fan Zhang,Yihui Wang,Xiujuan Wu,Hao Zhang,Shan Huang,Ying Yang,Adi Xie,Mingyan Wang
An enzyme-free glucose electrochemical sensor with high sensitivity and selectivity is highly attractive. In this work, an enzyme-free glucose sensor with Cu 2 O hollow microspheres (Cu 2 O HMs) was prepared via hydrothermal method. The glucose sensor constructed by the prepared Cu 2 O HM structure exhibited a low detection limit of 0.13 μM, a high sensitivity of 277.1 μA/mM cm 2 , and the wide linear ranges of 0.05–1.5 and 1.5–6.0 mM. Furthermore, anti-interference tests indicated that the prepared sensor exhibited good selectivity for glucose and practical application in human serum. The Cu 2 O sensor has great application potential in the development of enzyme-free glucose sensor.
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ACS Applied Bio Materials
·
2020
·
IF 0
Chang Liu,Xinrui You,Dingkun Lu,Guoyue Shi,Jingjing Deng,Tianshu Zhou
Nowadays, the environmental risk factors for Alzheimer’s disease (AD) have received widespread attention. Two major amyloid-β peptide (Aβ) variants, Aβ42 and Aβ40, play a pivotal role in the etiology of AD and the concentration ratio of which (i.e., Aβ42%) has been suggested to be the superior biomarker for AD. In this study, an “aggregation-based colorimetric sensor array” for the simultaneous identification and detection of Aβ40 and Aβ42 with structural similarity was established based on gelsolin-modified silver nanotriangles (Ag NTs) and silver nanorods (Ag NRs). Different aggregation behaviors of gelsolin-modified Ag NTs and Ag NRs in the presence of Aβ42 and Aβ40 resulted in different color and spectral changes, which could be quantitatively analyzed in terms of unique spectral patterns by principal component analysis. With the colorimetric sensor array employed here, the fluctuation of Aβ42% in different brain regions of rats exposed to Cd2+ could be directly monitored. The downward trend of Aβ42% accompanied by variations of other biochemical indicators suggested that subchronic Cd2+ exposure possibly triggered the onset of AD through the intervention of lipid peroxidation pathway. Furthermore, in vivo monitoring the downtrend of Aβ42% in cerebrospinal fluid (CSF) could also be realized, which offers a great opportunity for early diagnosis and treatment of AD that may be induced by environmental factors with CSF Aβ42% as a reliable indicator.
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