MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Zhengfang Liang,Yunzhan Xie,Hongbing Zhou,Zilu Zhang,Yuanxun Gong,Jiayi Zhang,Yue Huang,Qianli Tang,Kai Zhang,Xianjiu Liao
MicroRNA-21 (miR-21) is a critical biomarker involved in various pathological processes, yet its low abundance in biological fluids poses challenges for accurate detection. Herein, we present a highly sensitive electrochemiluminescence (ECL) biosensor for miR-21 detection. The system integrates a multi-stage amplification cascade that begins with toehold-mediated strand displacement (TMSD) and continues through T7 RNA polymerase transcription and CRISPR/Cas13a-mediated collateral cleavage. The sensing interface was constructed by immobilizing ferrocene-labeled DNA probes onto a conductive AuNPs/Ti₃C₂Tx/Ru(II)-PEI nanohybrid-modified electrode. In the absence of miR-21, ferrocene effectively quenched the ECL signal. Upon target recognition, TMSD activates a split T7 promoter/template system, triggering RNA transcription. The resulting single-stranded RNAs activate Cas13a, which cleaves DNA probes and restores the ECL emission. Under optimized conditions, the biosensor exhibited a wide dynamic range from 10 aM to 500 fM and a detection limit as low as 5.23 aM. It also demonstrated excellent specificity, repeatability (RSD = 4.3 %), and recovery (99.93–106.20 %) in spiked serum samples. This work provides a versatile and modular ECL sensing platform for ultrasensitive miRNA detection, offering promising applications in clinical diagnostics and precision medicine.
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Chengkai Liu,Yuan Tian,Yongling An,Qinglin Yang,Shenglin Xiong,Jinkui Feng,Yitai Qian
Gel electrolytes are key components for flexible energy storage devices. However, disadvantages such as poor ionic conductivity and mechanical behavior limit the practical applications of gel electrolytes. Herein, two-dimensional TiO 2 nanosheets are fabricated from Ti 3 C 2 T x MXene by a one-step hydrothermal reaction . The structure and component of Ti 3 C 2 T x MXene can be easily controlled by modulating the synthesis conditions. Influences of TiO 2 nanosheets content in PVA-based gel electrolyte are explored, which brings higher ionic conductivity and better mechanical properties with suitable additive amount. As a consequence, with the hybrid gel electrolyte, highly stable Zn plating/stripping is achieved (over 3000 h at 0.5 mA cm −2 ). Full Zn||PVA-Zn(CF 3 SO 3 ) 2 -TiO 2 ||V 2 O 5 cell shows high capacity (216 mAh g −1 after 115 cycles) and excellent cycling performance. This work provides an alternative route to develop high performance hybrid gel electrolyte for flexible energy storage devices such as Li/Na/K/Zn and supercapacitors.
研究领域:
材料科学
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电化学
·
能源存储
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纳米材料
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高分子化学
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固态离子学
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先进电池技术
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DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2023
·Vol. 34
·期 4
·1-12
·
IF 2.8
Ni Wentao,Yang Hengyu,Liu Xiong,Liang Yongle,Wu Banghui,Zhang Huaijun,Xu Guobao,Wei Xiaolin,Yang Liwen
Although vanadium-based compounds are considered to be reliable zinc storage materials due to their high theoretical specific capacity, notorious poor conductivity and unstable structure hamper their practical applications. Herein, novel two-dimensional (2D) sandwich-like heterostructures of amorphous vanadium dioxide uniformly grown on two sides of ultrathin MXene nanosheets (A-VO x /M heterostructures) are constructed by ion adsorption method and following low-temperature annealing, which can be readily incorporated into carbon nanotube (CNT) network to obtain freestanding cathodes for aqueous zinc-ion batteries. The combination of 2D heterostructure, amorphous framework and conductive substrate endows A-VO x /M heterostructures with short ion diffusion pathway, high chemical stability, extra active sites and superior electrical conductivity. The freestanding A-VO x /M heterostructured cathodes for aqueous zinc-ion batteries exhibit a remarkable discharge capacity of 362 mAh g −1 at 0.2 A g −1 and high-rate capability of 202 mAh g −1 at 15 A g −1 as well as admirable cycling stability with a capacity decay of only 0.0043% per cycle over 3000 cycles. Besides, due to the outstanding conductivity and stability of freestanding A-VO x /M heterostructured cathodes, soft-package batteries are assembled with steady electrochemical performance, suggesting brilliant future in the field of energy storage.
研究领域:
材料科学
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电化学
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能源存储
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纳米材料
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固态物理
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应用化学
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Guannan Zhang,Ying Lu,Jianbo Song,Di Huang,Meiwen An,Weiyi Chen,Peide Han,Xiaohong Yao,Xiangyu Zhang
After resection of bone tumour, the risk of cancer recurrence and numerous bone defects continues to threaten the health of patients. To overcome the challenge, we developed a novel multifunctional scaffold material consisting mainly of nano-hydroxyapatite particles ( n -HA), MXene nanosheets and g-C 3 N 4 to prevent tumour recurrence and promote bone formation. N -HA has the potential to restrict the growth of osteosarcoma cells, and the combination of MXene and g-C 3 N 4 enables the scaffolds to produce photodynamic and photothermal effects simultaneously under near infrared (NIR) irradiation. Surprisingly, n -HA can further enhance the synergistic anti-tumour function of photodynamic and photothermal, and the scaffolds can eradicate osteosarcoma cells in only 10 min at a mild temperature of 45 ℃. Moreover, the scaffold exhibit exceptional cytocompatibility and possesses the capacity to induce osteogenic differentiation of bone marrow mesenchymal stem cells. Therefore, this multifunctional scaffold can not only inhibits the proliferation of bone tumour cells and rapidly eradicate bone tumour through NIR irradiation, but also enhances osteogenic activity. This promising measure can be used to treat tissue damage after bone tumour resection.
研究领域:
生物医学工程
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材料科学
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癌症治疗
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组织工程
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Yangcheng Liu,Baoli Xu,Shengxue Wang,Qilin Liu,Zheng Xiang,Wanwei Jiang,Yang Wang
The excessive accumulation of benzophenone (BP) endocrine disruptors highlights the need to develop novel materials capable of efficient removal and precise, simultaneous monitoring of multiple BPs. Based on the characteristics of BPs, an accordion-like NH 2 –MXene-based composite material with rice grain–like 1,3,5-tris(4-aminophenyl)-benzene-1,3,5-benzenetricarbaldehyde covalent organic frameworks (TB–COF) on its surface after modification (TB–COF@NH 2 –MXene) was developed. The obtained TB–COF@NH 2 –MXene exhibited rich functional groups, an appropriate pore structure and suitable surface properties. Moreover, it exhibited a high saturation adsorption capacity (292.47–316.23 mg g −1 ), rapid kinetics (25 min) and excellent dynamic adsorption ability (1359–2548 BV). It demonstrated good selectivity and an excellent ability to capture BPs at low concentrations. Notably, dispersive solid-phase extraction based on TB–COF@NH 2 –MXene in combination with high-performance liquid chromatography–diode array detector enabled the simultaneous detection of trace BPs in river water, cookies, vermicelli, milk, coffee, tea and infant formula samples. This study provided practical guidance on environmental and food safety solutions.
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产品关联
DOI
PubMed
高影响因子
Journal of Macromolecular Science Part B-Physics
·
2023
·
IF 1.4
Bo Zhang,Ruixin Wang
Compared with other types of sensors, capacitive flexible pressure sensors (CFPS), with low sensitivity, are more susceptible to environmental changes. It is still a considerable challenge to achieve high sensitivity, excellent mechanical properties and long-time structural stability simultaneously. Targeting the aforementioned issues, herein, Ti3C2 (MXene) with high dielectric constant was firstly chemically modified with a poly(ionic liquid) (PIL) via surface-initiated ATRP, and then combined with a porous polyurethane foam (PUF) 3D network structure via a one-step blending foaming method. Thanks to the organic-inorganic hybrid network based on the PU/MXene porous structures and the uniformly distributed micro-capacitor structure provided by MXene@PIL, the mechanical properties, structural stability, flame retardancy and dielectric properties of the composite foam were all significantly enhanced. When the content of MXene@PIL was 10%, the sensitivity of CFPS based on this dielectric were 17.1, 5.2, and 2.5/KPa in the pressure ranges of 0-1 KPa, 1-12 KPa and 12-100 KPa, respectively. In addition, the sensor showed the response and recovery times of 88 and 82 ms under a low pressure of 355 Pa. The light, flexible sensor prepared in this work is expected to be used in wearable devices to monitor physiological signals, and it should also be a good candidate for the next generation of man-machine interface characterization devices.
研究领域:
材料科学
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高分子科学
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纳米技术
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传感器技术
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化学工程
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Temitope Fausat Ajibade,Huali Tian,Kayode Hassan Lasisi,Qiang Xue,Weihao Yao,Kaisong Zhang
Despite advances in membrane technology, the separation of complex oily wastewater using membrane filtration remains a daunting challenge for the industry. Recent approaches including membrane modification with two-dimensional (2D) nanosheets, showed susceptibility to swelling, fouling, and instability during operation. As a game-changer approach, a polyacrylonitrile (PAN) UF membrane modified with 3D nanostructured composite of MXene and O-MWCNT was introduced for the first time to treat complex oily wastewater. The composite membrane showed high separation performance of soluble dye-oil-water emulsion while maintaining high water permeability. Moreover, during the operational period, the composite membrane exhibits excellent antifouling and anti-swelling properties due to the synergetic effects conferred by the 3D nanostructures. Furthermore, the composite membrane possesses remarkable chemical stability evidenced by its high corrosion resistance when exposed to a strong acid (3 M HCl) and oxidant (NaOCl) solution for a long-time period. Overall, the operational stability was maintained in terms of flux and high rejection of oil and dye over a 45 h long-term operation. Consequently, this work provides an innovative, stable, and highly facile process for fabricating scalable UF composite membrane for the treatment of complex oily wastewater in a harsh chemical environment.
研究领域:
环境工程
·
膜技术
·
废水处理
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DOI
高影响因子
Applied Materials Today
·
2020
·
IF 8.352
Xin Du,Tianyu Zhao,Ziyuan Xiu,Zipeng Xing,Zhenzi Li,Kai Pan,Shilin Yang,Wei Zhou
Novel BiVO 4 @ZnIn 2 S 4 /Ti 3 C 2 MXene quantum dots (QDs) assembly all-solid-state direct Z-scheme photocatalyst is fabricated via in-situ growth combined with two-step solvothermal strategy, which forms a hierarchical core-shell structure. The proper energy band structure of BiVO 4 and ZnIn 2 S 4 and the formation of a good solid-solid contact interface between them promote the construction of Z-scheme system, which achieves effective charge separation. It is surprisingly discovered that Ti 3 C 2 MXene QDs can be applied as cocatalysts for photocatalytic overall water splitting, which could accelerate the surface redox kinetics of the catalyst due to the unique properties of Ti 3 C 2 MXene QDs . In particular, due to its excellent metal conductivity, a Schottky barrier can be formed at the interface in contact with ZnIn 2 S 4 , further promoting charge separation. BiVO 4 @ZnIn 2 S 4 /Ti 3 C 2 MXene QDs achieves effective visible-light-driven pure water splitting into O 2 and H 2 evolution rates up to 50.83 and 102.67 μmol g −1 h −1 (~1:2). In addition, it also shows high photocatalytic degradation Bisphenol A efficiency of ~96.4 %. The high photocatalytic performance can be ascribed to the all-solid-state direct Z-scheme structure favoring spatial charge separation, Ti 3 C 2 MXene QDs as cocatalysts promoting proton reduction, and hierarchical core-shell structure offering more surface active sites. This work provides new insights to fabricate high-performance direct Z-scheme assembly system.
研究领域:
材料科学
·
光催化
·
能源化学
·
纳米材料
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环境科学
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半导体物理
·
表面科学
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Qingying Feng,Yingqing Zhan,Wei Yang,Hongyu Dong,Ao Sun,Lingli Li,Ximin Chen,Yiwen Chen
The membrane fouling from oils, soluble organic matters, and microorganism is inevitable in practical application of oil/water separation, which easily causes the decline in flux and service life of membrane. Therefore, developing the advanced separation membrane with high flux and anti-fouling feature is still a big challenge. Herein, we report a facile strategy to prepare the multifunctional [email protected] /PEN fibrous composite membrane by the self-assembly of [email protected] hybrid on electrospun poly (arylene ether nitrile) (PEN) porous support. In the hierarchical skin layer of fibrous composite membrane, the silver nanoparticles (AgNPs) were anchored onto the MXene surface via the self-reduction of silver nitrate, in which the MXene acted as reductant. Meanwhile, the [email protected] hybrid was stabilized and modified by the bio-inspired dopamine triggered crosslinking with polyethyleneimine. Because of regulated interlayer spacing, super-hydrophilic property, and porous supporting layer, the [email protected] /PEN fibrous composite membrane exhibited the ultra-high permeance (up to 11957.5 L·m −2 ·h −1 ·bar −1 ) for different oil–water emulsions while maintaining high-level rejection rate (99.13%), which was far beyond other MXene-based composite membranes reported before. Moreover, the fibrous composite membrane showed the satisfactory photocatalytic degradation rates for the methyl orange (15 ppm, 95.24%) and crystal violet (15 ppm, 95.61%) in 60 min, demonstrating the photocatalytic self-cleaning ability for organic pollutants. In addition, the fibrous composite membrane exhibited ∼ 99.99% E. coli growth inhibition, achieving the favorable antibacterial effect. Therefore, the low oil adhesion, photocatalytic self-cleaning, and antibacterial effect contributed to the synergistically enhanced anti-fouling, which enabled the membrane material to maintain high separation efficiency and long-term usage in complex multi-pollutant environments. The combination of high permeability and enhanced anti-fouling performance makes the fibrous composite membrane an ideal candidate for the fast purification of emulsified oily wastewater.
研究领域:
环境科学
·
材料科学
·
化学工程
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Yi Wang,Jun Cao,Jinghe Guo,Jianglei Zhang,Guangsen Liu,Dong Wang,Weimeng Si,Jia Song,Xiuxia Meng,Guangwu Wen
To meet the rapid development of flexible supercapacitors with both high energy density and power density, hybrid ion capacitors like lithium and sodium ion capacitors have attracted more and more attention. However, the hidden danger associated with the using of organic electrolytes limit their practical application. In this regard, a new configuration flexible zinc-ion hybrid supercapacitor (ZHSC) based on free-standing films of RGO-V 2 O 5 (RGV) battery-type cathode and RGO-MXene (RGM) capacitor-type anode in aqueous electrolyte has been designed. The RGM/RGV system consists of specific layered structure, short ion diffusion pathway, high electrical conductivity and exceptional structural stability. As a result, the ZHSC based on RGM/RGV exhibits excellent electrochemical performance, including a large specific capacity of 175 F g −1 at 0.5 mV s −1 , a maximum energy density up to 107.2 Wh kg −1 (321.6 W kg −1 ) and a high capacitance retention of 81% of its initial capacitance (10,000 cycles). Additionally, the ZHSC displays a high specific capacity of 125 F g −1 at 0.5 mV s −1 even in an aqueous gel electrolyte. More importantly, supercapacitors based on the composite films exhibit stable flexibility electrochemical performance. The investigation provides an essential strategy to synthesize composite films for application in high performance flexible hybrid supercapacitors.
研究领域:
材料科学
·
能源存储与转换
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DOI
高影响因子
IONICS
·
2023
·Vol. 30
·期 3
·1457-1467
·
IF 2.8
Xu Wengang,Zhang Xiaonan,Li Junhao,Chen Xiaobo,Lan Lin,Zhang Jun,Ling Francis Chi-Chung,Ru Qiang
The scaffolded hierarchical CeVO 4 /V 2 CT x -MXene composite is harvested to boost the performance of vanadium oxides in aqueous zinc-ion batteries. Benefiting from the high electronic-ion conductivity of V 2 CT x -MXene and the multilayered structure of the composite, CeVO 4 /V 2 CT x -Mxene cathode depicts the advantages of the acceptable zinc storage and ionic reaction kinetics. Compared with pure CeVO 4 , CeVO 4 /V 2 CT x -MXene cathode shows a reversible discharge capacity of 295.0 mAh g −1 at 1 A g −1 , capacity retention of 81.6% over 3000 cycles at 5 A g −1 , and good high-rate performance of 233.5 mAh g −1 at 8 A g −1 . The quasi-solid-state batteries of CeVO 4 /V 2 CT x -MXene demonstrate well mechanical deformability and good cycling performance. This work provides a reference for solving the problem of vanadium-based materials for aqueous zinc-ion batteries.
研究领域:
材料科学
·
能量存储
·
电化学
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Shiquan Li,Jianhua Zhu,Wei Lu,Zhaoxi Liu,Zhuosen Wang,Liu Wang,Yapeng Tian,Xinwei Cui
Sodium-selenium (Na-Se) batteries have gained attention due to their high energy density and power density, resulting from the liquid–liquid reaction at the interface in the dimethoxyethane electrolyte. Nevertheless, the pronounced shuttle effect of polyselenides causes low coulomb efficiency and inadequate cycling stability for Na-Se batteries. Herein, the iron nanoparticles surface modified accordion-like Ti 3 C 2 T x MXene (MXene/Fe) synthesized via the molten salt etching is utilized as the host of Se species for high-performance Na-Se battery cathode. Benefiting from the layered structure and chemical adsorption of accordion-like MXene, the shuttle effect of the cathode is effectively inhibited. Simultaneously, electrochemical kinetics is boosted due to the catalytic effect of Fe nanoparticles, which facilitate the transformation of polyselenide from long-chain to short-chain, contributing to pseudocapacitive capacity. Consequently, the Se-based cathode delivers a steady capacity of 575.0 mA h g −1 at 0.2 A/g, and even a high capacity of 500 mAh/g at 50 A/g based on the mass of Se@MXene/Fe electrode, indicating the ultrafast Na + ion storage. Most notably, this structure demonstrated remarkable long-term cycling stability for 5000 cycles with a high capacity retention of 97.4 %. The electrochemical energy storage mechanism is further revealed by in situ Raman. Herein, the confinement-catalysis structure shines light on inhibiting shuttling and facilitating ultrafast ion storage.
研究领域:
材料科学
·
电化学
·
能源存储
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DOI
高影响因子
危险品化学品经营许可证（带存储）