RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
·
2024
·Vol. 60
·期 10
·1999-2003
·
IF 0.8
Li C. L.,Wang S. Y.,Zhan M. R.,Chen C. C.,Wang Z. X.
Chiral monosubstituted cyclohexanediamine catalyst, namely (1 R ,2 R )-2-(piperidin-1-yl)cyclohexan-1-amine ( Cat1 ) has been efficiently synthesized and used to catalyze the aldol reaction of cyclohexanone and 2-(trifluoromethyl)benzaldehyde to obtain ( R )-2-{( S )-hydroxy[2-(trifluoromethyl)phenyl]methyl}cyclohexan-1-one. The catalyst (20 mol %) provided high yield (up to 85%) and excellent enantioselectivity (95.6% ee ) in water solution in three parallel tests.
研究领域:
有机化学
·
催化化学
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ELECTROCHIMICA ACTA
·
2017
·
IF 4.798
Kang Ma,Qian Tang,Chun-rong Zhu,Jun-fei Long,Cheng-bin Gong,Xiang-kai Fu
This work reports novel dual-colored and fast switching electrochromic materials based on pyridinium salts , 1,1′,1″,1‴-tetrakis(4,4′,4″,4‴-tetrapyridyl)cyclobutane derivatives (TPCBDs). TPCBDs show outstanding electrochromic properties including fast electrochromic switching, dual color, reasonable contrast, low driving voltage, and good stability. TPCBDs are promising candidates for visible electrochromic displays because of their remarkable electrochromic behaviors.
研究领域:
材料科学
·
电化学
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ChemistrySelect
·
2023
·Vol. 8
·期 10
·e202203687
·
IF 2.1
Min Zhang,Shenyong Ren,Qiaoxia Guo,Baojian Shen
Graphical Sheet-like zeolite TS-1 was synthesized under hydrothermal conditions by adding seed and urea. Liquid seed and pre-crystallization could adjust thickness of sheet-like sample in b-axis direction. Epoxidation of 1-hexene with H 2 O 2 catalyzed by sheet-like TS-1 gave high selectivity of 1,2-epoxyhexane. In zeolite TS-1, the straight channel parallelled to the b-axis direction has larger pore size and thus is main diffusion channel for molecules. Shorter b-axis brings about shorter diffusion channel, which can leads to higher adsorption and diffusion rate. Therefore, with regard to the morphology modification of MFI zeolites, many studies touch on short b-axis zeolites have been reported. Unfortunately, most of the preparation processes require harsh synthesis conditions and complex organic templates, and they are not conducive to large-scale applications. In this work, cheap organic additive urea and seed crystals were added to synthesize sheet-like TS-1, which boasts short b-axis. At the same time a pre-crystallization was performed at the aging solution stage. In the b-axis direction, the zeolite TS-1 prepared in this way had a minimum thickness of about 50 nm. This is because urea can inhibit the growth of crystals in the b-axis direction, and the guiding effect of the seed liquid also plays the function of adjusting the b-axis thickness. In the epoxidation of 1-hexene with H 2 O 2 when catalyzed by sheet-like TS-1, the selectivity of the target product 1,2-epoxyhexane was significantly improved.
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Yangrui Wang,Mengtong Sun,Xiaoling Cui,Yongyue Gao,Xinran Lv,Jianrong Li,Fengling Bai,Xuepeng Li,Defu Zhang,Kai Zhou
Vibrio harveyi is one of the main pathogenic bacteria in the aquaculture industry, and quorum sensing (QS) plays key role in its pathogenicity. Previous studies have demonstrated that a metabolite with protein properties isolated from Lactococcus lactis LY3-1 showed anti-QS activity against V. harveyi . In this study, this metabolite of L. lactis LY3-1 was identified as peptide LQLY3-1, with a 1.09 kDa molecular mass, which was purified via ethyl acetate extraction followed by ultrafiltration, Sephadex G25 gel chromatography, and high-performance liquid chromatography. Its amino acid sequence was ALSLVKIHGR, as demonstrated by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Crude extracts of peptide LQLY3-1 at sub-minimum inhibitory concentrations inhibited V. harveyi biofilm formation and the production of virulence factors, including exopolysaccharide, proteolytic enzymes, hemolysin, gelatinase, and motility, albeit without inhibiting bacterial growth. Scanning electron microscopy images indicated that the crude extracts of peptide LQLY3-1 disrupted the integrity of the V. harveyi biofilm. Additionally, molecular docking analysis indicated that peptide LQLY3-1 could competitively bind to the LuxN receptor protein with its natural ligand N-octanoyl- l -homoserine lactone, thereby blocking the signal transmission of the QS system. These results suggested that peptide LQLY3-1 can be used as a promising QS inhibitor to control V. harveyi pathogenicity.
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JOURNAL OF HEADACHE AND PAIN
·
2022
·Vol. 23
·期 1
·1-14
·
IF 8.588
Pan Qi,Wang Yunfeng,Tian Ruimin,Wen Qianwen,Qin Guangcheng,Zhang Dunke,Chen Lixue,Zhang Yixin,Zhou Jiying
Background Central sensitization is an important pathophysiological mechanism of chronic migraine (CM), and microglia activation in trigeminocervical complex (TCC) contributes to the development of central sensitization. Emerging evidence implicates that blocking sphingosine-1-phosphate receptor 1 (S1PR1) can relieve the development of chronic pain and inhibit the activation of microglia. However, it is unclear whether S1PR1 is involved in the central sensitization of CM. Therefore, the purpose of this study is to explore the role of S1PR1 and its downstream signal transducers and activators of transcription 3 (STAT3) signaling pathway in the CM, mainly in inflammation.Methods Chronic intermittent intraperitoneal injection of nitroglycerin (NTG) established a mouse model of CM. First, we observed the changes and subcellular localization of S1PR1 in the trigeminocervical complex (TCC). Then, W146, a S1PR1 antagonist; SEW2871, a S1PR1 agonist; AG490, a STAT3 inhibitor were applied by intraperitoneal injection to investigate the related molecular mechanism. The changes in the number of microglia and the expression of calcitonin gene-related peptide (CGRP) and c-fos in the TCC site were explored by immunofluorescence. In addition, we studied the effect of S1PR1 inhibitors on STAT3 in lipopolysaccharide-treated BV-2 microglia.Results Our results showed that the expression of S1PR1 was increased after NTG injection and S1PR1 was colocalized with in neurons and glial cells in the TCC. The S1PR1 antagonist W146 alleviated NTG-induced hyperalgesia and suppressed the upregulation of CGRP, c-fos and pSTAT3 in the TCC. Importantly, blocking S1PR1 reduced activation of microglia. In addition, we found that inhibiting STAT3 signal also attenuated NTG-induced basal mechanical and thermal hyperalgesia.Conclusion sOur results indicate that inhibiting S1PR1 signal could alleviate central sensitization and inhibit microglia activity caused by chronic NTG administration via STAT3 signal pathway, which provide a new clue for the clinical treatment of CM.
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PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2018
·
IF 5.091
Qiang Wan,Huiyong Wang,Shuangyu Li,Jianji Wang
Liquid-phase exfoliation of graphite is a promising method to produce graphene in large quantities. Selection of the solvent is the most important factor in determining the productivity of liquid-phase exfoliation and stability of the graphene dispersion. However, only low concentrations of graphene dispersion have been achieved in most of the solvents, and the solvents usually employed are toxic up to now. To address the performance and environmental safety issues of solvent, renewable solvents water and 1, 1, 3, 3-tetramethylurea (TMU) are explored as a mixture to exfoliate graphite into graphene in the present work. It is found that water-TMU mixed solvent is a powerful solvent to obtain a few-layer graphene, and the yield at the water volume faction of 0.3 was 4.5 times that in neat N -methylpyrrolidinone (NMP). The solvent-cosolvent interactions (water-TMU heteroassociation) are a critical factor in the liquid-phase exfoliation of graphene. The results reported in this work may provide a guide to rational design of a sustainable solvent system and to improve the yield and stability of the exfoliated graphene.
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Xingxing Cui,Hongyang Lyu,Yongming Chai,Bin Liu,Dongfeng Zhao,Chenguang Liu
The strong acidity on the external surface of ZSM-5 is a primary factor resulting in the low BTX selectivity and catalyst deactivation during the olefin aromatization. In this study, a membrane-restricted Silicalite-1@ZSM-5 core–shell structured catalytic catalyst was designed and constructed for 1-hexene aromatization using a hydrothermal coating method. TEM and NMR results confirmed the complete coverage of Silicalite-1 on the surface of ZSM-5, with a shell thickness of 50 nm. The further reaction of the TIPB (1,3,5-triisopropylbenzene) molecular probe reactions demonstrated the passivation of the acid sites on ZSM-5 external surface. The inert shell layer passivated the acid sites on the external surface, thereby suppressing the isomerization of PX and the side-chain alkylation reaction of light aromatics. Compared to ZSM-5, the Silicalite-1@ZSM-5 catalyst exhibited a 37.15 % increase in BTX selectivity, a 58.65 % increase in PX selectivity, significantly reduced coke deposition, and demonstrated better stability. This strategy of in-situ epitaxial growth of inert shell layers holds significant promise for enhancing the selectivity of shape-selective catalysts and extending catalyst lifetime.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Wanting Zhang,Jiawei Ruan,Xinzi Wu,Qian Liu,Kunchi Xie,Lifang Chen,Zhiwen Qi
The transformation of captured CO 2 into highly-valued dimethyl carbonate (DMC) is a promising approach for CO 2 capture and utilization. However, the direct synthesis of DMC from CO 2 and methanol is limited by high activation barrier derived from inert CO 2 and thermodynamic equilibrium constraints. Herein, three 1-butyl-1-methylpyrrolidinium (BMP)-based ionic liquid (ILs) with polar pyrrole, pyrazole, and 1,2,4-triazole (Tz) azole anions were designed to integrate CO 2 absorption and transformation into DMC. [BMP][Tz] exhibits a relatively high CO 2 uptake capacity of 0.6 mol·mol IL −1 and DMC yield reaches 12.2 % under mild reaction conditions of atmospheric temperature and pressure in 12 h. The reaction equilibrium thermodynamic model reveals that the process involves a combination of 1:1 and 2:1 stoichiometric reaction between [BMP][Tz] and CO 2 . Density functional theory calculations verify that [BMP][Tz] with increased absorption efficiency of azole anions promotes critical bond activation (particular C − O and O − H bonds), thereby enhancing catalytic efficiency. Besides, the reaction mechanism is clarified by the calculation of intermediates and transition state, wherein [BMP][Tz] can efficiently decrease the energy barrier of the rate-controlled step, which involves the insertion of CH 3 O − into CH 3 OCOO − species. Furthermore, polarity-induced phase separation of DMC from the IL phase to solvent phase favors DMC generation by breaking through the reaction equilibrium. The integration of CO 2 absorption-reaction-extraction based on basic and polar ILs, provides a promising approach for CO 2 capture and utilization.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Maoqiao Xiang,Miao Song,Qingshan Zhu,Yafeng Yang,Chaoquan Hu,Zhiwei Liu,Hongdan Zhao,Yu Ge
Two-dimensional (2D) single crystal transition metal nitrides (TMNs) with exposed active crystal planes have great value for fundamental science and technological applications. However, it is still a great challenge to synthesize the non-layer crystal structured 2D single crystal TMNs, e.g. the face-centered cubic (FCC) 2D single crystal TiN, which would have distinct properties. Herein, for the first time, an induction-inhibition strategy was successfully developed to break through the intrinsic limitation and the weak anisotropic growth tendency of the FCC TiN. Single-crystalline TiN nanosheet (about 5.14 nm thickness) arrays with exposed {1 1 1} active facets were synthesized successfully on a large scale by the new strategy, where the layer arrays were induced by a layered TiNCl intermediate formed by the chemical vapor deposition reaction of a new titanium source (TiCl 3 ) with NH 3 and the exposed {1 1 1} facets was caused by the chemisorbed Cl inhibitor. The special 2D single crystal TiN arrays exhibited excellent catalytic activity and durability for hydrogen evolution reaction (HER) from water electrolysis.
研究领域:
材料科学
·
电催化
·
纳米材料
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化学气相沉积
·
能量转换
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2014
·
IF 6.007
Ze’ai Huang,Qiong Sun,Kangle Lv,Zehui Zhang,Mei Li,Bing Li
In this paper, effect of contact interfaces of high-energy TiO 2 , (1 0 1) and (0 0 1) facets, with g-C 3 N 4 on the photocatalytic activity of g-C 3 N 4 /TiO 2 hybrid was studied using TiO 2 hollow nanobox (TiO 2 -HNB) assembly from high-energy TiO 2 nanosheets (TiO 2 -NS) as model. The prepared photocatalyst was characterized by X-ray diffraction (XRD), transmission electron microscope (TEM), scanning electron microscopy (SEM), nitrogen sorption , Fourier transform infrared spectroscopy (FT-IR), diffuse reflectance spectroscopy (DRS) and X-ray photoelectron spectrometer (XPS). The photoreactivity of the photocatalyst was evaluated by measure the formation rate of photo-induced hydroxyl radicals ( OH) using coumarin as a probe molecule and photocatalytic degradation of Brilliant Red X3B (an anionic dye) under UV irradiation ( λ = 365 ± 10 nm). It was found that g-C 3 N 4 /TiO 2 -HNB forms direct Z-scheme photocatalytic system, which shows superior enhancement on the photocatalytic activity of TiO 2 than g-C 3 N 4 /TiO 2 -NS. It is by contacting g-C 3 N 4 with (1 0 1) facets, g-C 3 N 4 can efficient remove the photo-generated electrons accumulated on (1 0 1) facets of high-energy TiO 2 , which results in spatially isolated photo-generated electrons and holes, enhancing the photocatalytic activity.
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SYNTHESIS-STUTTGART
·
2019
·Vol. 51
·期 21
·4048-4065
·
IF 2.867
Rui-Xiang Wang,Zhuang Fang,Guanyinsheng Qiu,Wenlin Xie,Jin-Biao Liu
The copper-catalyzed synthesis of 3-vinylisocoumarin-1-imine is reported. The transformation proceeds smoothly with good yields in THF and the regioselectivity was determined by a O-nucleophilic 6-endo cyclization. Studies on the mechanism indicate that copper trifluoroacetate serves as a Lewis acid, and the use of vinyl-connected 2-alkynylbenzamide is important for this O-nucleophilic 6-endo cyclization.
研究领域:
有机化学
·
合成化学
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高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2025
·
IF 8.3
Yongliang Xu,Lei Xiang,Lanyun Wang,Zecheng lv,Yao Li,Hao Shao,Haidong Chen,Kun Zhang,Xiaodong Feng
Hydrate-based hydrogen storage technology enables the solid-state stabilization of hydrogen by encapsulating H 2 molecules within a clathrate lattice structure, representing a promising strategy for industrial-scale gas storage. This study focuses on enhancing the gas storage performance and stability of H 2 –CH 4 binary hydrate. Experiments on the formation and dissociation of H 2 –CH 4 hydrates were conducted under a pressure of 6.0 MPa. The study examines the effects of C 8 F 18 (6 wt%, 8 wt%, 10 wt%) and 1,3-DIOX (4mol%, 5mol%, 6mol%) on H 2 –CH 4 (with a ratio of 1:1) hydrate. The results indicate that in the composite systems containing 5mol%, 1,3-DIOX and 8 wt% C 8 F 18 , a synergistic promotion effect was observed. The nucleation temperature was further increased by 3.8 K compared to the single 1,3-DIOX system. The induction time was shortened by 146.9 min. Gas consumption improved to 0.14446 mol. Furthermore, In 4mol%1,3-DIOX and 6 wt% C 8 F 18 compound system prolonged the pre-dissociation 48.33min relative to the 1,3-DIOX system. C 8 F 18 enhances the self-preservation of the hydrate, an effect that is not present with only 1,3-DIOX. This effect becomes more pronounced as the concentration of C 8 F 18 increases. Generally, the 1,3-DIOX + C 8 F 18 can play a synergistic effect on enhancing the gas storage performance and stability of hydrates.
研究领域:
物理化学
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能源材料
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气体储存
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水合物化学
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工业催化
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高影响因子
危险品化学品经营许可证（带存储）